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    AN APPARATUS AND A METHOD FOR INVESTIGATION OF MICROTITER PLATES SUBJECTED TO ORBITAL SHAKING
    192.
    发明公开
    AN APPARATUS AND A METHOD FOR INVESTIGATION OF MICROTITER PLATES SUBJECTED TO ORBITAL SHAKING 有权
    DEVICE AND METHOD FOR微孔板的影响下轨道摇床调查

    公开(公告)号：EP2350613A1

    公开(公告)日：2011-08-03

    申请号：EP09783713.2

    申请日：2009-10-02

    Applicant: Enzyscreen B.V.

    Inventor： DUETZ, Wouter Adriaan

    IPC: G01N21/25 ,  B01F11/00 ,  B01F15/00

    CPC classification number: G01N21/253 ,  B01F11/0014 ,  B01F15/00253 ,  G01N2201/04 ,  G01N2201/10

    Abstract: The invention relates to an apparatus, a method and a computer program for investigation of microtiter plates subjected to orbital shaking. The apparatus 10 comprises a housing 7, microtiter plates Ia, Ib, Ic, Id comprising wells, which may be arranged under respective clamp elements 2a, 2b, 2c, 2d arranged to hold the microtiter plate down to the frame 5. The apparatus 10 further comprises a processor 8 conceived to interrupt the motor of the frame 5 for a suitable interrupt period and to trigger the flatbed scanner 3a, 3b for generating two-dimensional images of respective bottoms of the wells present in the microtiter plates 1a, 1b, 1c, 1d. The flatbed scanner 3a, 3b is preferably mounted on respective frames 6a, 6b for support. The frames 6a, 6b may be attached to the housing 7. The processor 8 may be operable using a computer program 8a. The processor may be arranged to store the acquired images in a suitable memory unit 9. Alternatively or additionally, the processor 8 may be arranged to carry-out on-line or off-line analysis of the scan data using calibration data 8b and to adapt shaking mode using a signal S.

    Analytical method and analytical apparatus using test strips
    195.
    发明公开
    Analytical method and analytical apparatus using test strips 失效
    Analyseverfahren und -vorrichtung unter Verwendung von Teststreifen。

    公开(公告)号：EP0538830A1

    公开(公告)日：1993-04-28

    申请号：EP92118011.3

    申请日：1992-10-21

    Applicant: HITACHI, LTD.

    Inventor： Yoshida, Kasumi ,  Shindo, Isao ,  Kai, Susumu ,  Kimura, Yutaka

    IPC: G01N35/00

    CPC classification number: G01N35/00029 ,  G01N2035/00108 ,  G01N2035/0441 ,  G01N2035/1025 ,  G01N2201/04 ,  Y10T436/112499 ,  Y10T436/113332 ,  Y10T436/114165

    Abstract: A sample container (20) containing a urine sample (22) is transferred by a sample positioning device to a liquid level sensing position. At this sensing position, the liquid level in the sample container is detected by a level sensor (39), followed by transfer of the sample container to a dipping position. A liquid level rising member (40) is then inserted to the sample container. While being held by a handling device, a test strip (23) is dipped into the sample in the sample container with the liquid level raised. Thereafter, the test strip (23) is lifted out of the sample container (20) and transferred to a measuring device. Color development in reagent sections on the test strip is measured by a photometer in terms of the reflected light strength. With the present invention, analysis using test strips can be implemented even when the sample volume sampled into the sample container is small.

    Abstract translation: 含有尿液样品（22）的样品容器（20）通过样品定位装置转移到液位检测位置。 在该检测位置，通过液位传感器（39）检测样品容器中的液位，然后将样品容器转移到浸渍位置。 然后将液位升高构件（40）插入到样品容器中。 当被处理装置保持时，将测试条（23）浸入样品容器中，液面升高。 此后，将测试条（23）从样品容器（20）中提出并转移到测量装置。 根据反射光强度，通过光度计测定试片上的试剂部分的显色性。 通过本发明，即使在取样到样品容器中的样品体积小的情况下，也可以实施使用测试条的分析。

    Imaging immunoassay detection system and method
    197.
    发明公开
    Imaging immunoassay detection system and method 失效
    Abbildendes Immunoprobe-Nachweissystem und Verfahren。

    公开(公告)号：EP0194132A2

    公开(公告)日：1986-09-10

    申请号：EP86301523.6

    申请日：1986-03-04

    Applicant: Murex Corporation

    Inventor： Leaback, David Herbert

    IPC: G01N21/76 ,  G01N33/53

    CPC classification number: G01N21/76 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00621 ,  B01J2219/0063 ,  B01J2219/00659 ,  B01J2219/00707 ,  G01N33/535 ,  G01N33/542 ,  G01N33/54373 ,  G01N2201/04

    Abstract: @ Light generated by one ormore chemical reactions in a discrete array is determined, both as to emissions per reaction and as to relative location of the reactions, e.g. using a system comprising:

    a sample carrier having spaced-apart discrete areas each containing a reactant capable of emitting light photons if a reaction takes place;
    a photon receiver, for receiving photons emitted from each reaction simultaneously; and
    a signal generator coupled to the photon receiver, for generating a signal representing the x-y location of each reaction.

    The signal generator may be a photomultiplier, charge-coupled device or vidicon tube. The invention is particularly suited to the determination of reactions and non-reactions, e.g. between an array of labelled antibodies and a specimen potentially containing one or more complementary antigens, in an immunoassay.

    Abstract translation: 确定在离散阵列中由一个或多个化学反应产生的光，关于每个反应的排放和反应的相对位置，例如， 使用的系统包括：样品载体，其具有间隔开的离散区域，每个区域包含如果发生反应则能够发射光子的反应物; 光子接收器，用于同时接收从每个反应发射的光子; 以及耦合到所述光子接收器的信号发生器，用于产生表示每个反应的x-y位置的信号。 信号发生器可以是光电倍增管，电荷耦合器件或摄像管。 本发明特别适用于测定反应和非反应，例如， 在标记抗体阵列和潜在地含有一种或多种互补抗原的样品之间进行免疫测定。

    A photometric light absorption measuring apparatus
    198.
    发明公开
    A photometric light absorption measuring apparatus 失效
    光学吸收测量装置

    公开(公告)号：EP0121404A3

    公开(公告)日：1985-11-06

    申请号：EP84302093

    申请日：1984-03-28

    Applicant: KABUSHIKI KAISHA TOSHIBA

    Inventor： Minekane, Tomiharu c/o Patent Division

    IPC: G01N21/25

    CPC classification number: G01J3/42 ,  G01J3/02 ,  G01J3/027 ,  G01J3/10 ,  G01J3/427 ,  G01N21/255 ,  G01N2201/04 ,  G01N2201/0696

    Abstract: A photometric light absorption measuring apparatus includes a central processing unit sending generator frequency data to a high power generator that pulses a light source intermittently to irradiate a liquid sample contained in a transparent receptacle. The intermittent light beams pass through optical guides, focusing lenses, light amplifiers and a slit aperture. A diffraction grating disperses the light beams and a light detector receives the spectral components and generates corresponding intensity signals which are passed through an amplifier and supplied to an arithmetical unit which receives frequency power generation signals from the central processing unit. A misfire detector sends signals to the arithmetical unit when the light source fails to flash. The arithmetical unit preselects two spectral components and calculates the concentration of a corresponding preselected constituent of the liquid sample from the average mean value of the intensity differences between the two preselected spectral components corrected to eliminate intensity data corresponding to non-flashes of the light source.

    Objektträger als Teil einer Photo- oder Fluorometereinrichtung
    199.
    发明公开
    Objektträger als Teil einer Photo- oder Fluorometereinrichtung 失效
    Objektträgerals Teil einer Photo-oder Fluorometereinrichtung。

    公开(公告)号：EP0067963A2

    公开(公告)日：1982-12-29

    申请号：EP82104298.3

    申请日：1982-05-17

    Applicant: Boehringer Ingelheim International GmbH

    Inventor： Lang, Kurt M.

    IPC: G01N21/25 ,  G01N21/64

    CPC classification number: G01N21/253 ,  G01N21/645 ,  G01N2201/04

    Abstract: Die Erfindung betrifft einen Objektträger als Teil einer Photo- oder Fluorometereinrichtung.
    In der Praxis werden die beiden Geräteeinrichtungen nebeneinander benötigt.
    Die Umrüstung von einem Photometer zu einem Fluorometer bzw. umgekehrt ist dabei aufwendig. Dies führte zu der Entwicklung einer Vielzahl lediglich objektgebundener Geräte beider Arten.
    Es ist deshalb Ziel der Erfindung, einen Objektträger zu nennen, der durch einfache Manipulation bzw. Umordnung praktisch jede der fallweise infrage stehenden Untersuchungen - unabhängig vom verwendeten Grundgerätetyp - zuläßt.
    Die erfindungsgemäße Lösung sieht einen als Blockeinheit 2 ausgebildeten Objektträger vor, der zur Aufnahme von Küvetten 6 oder Teststreifen 7 bestimmt ist, mit einschüben 5 für unterschiedliche Filter ausgerüstet ist und eine die Licht-oder Fluorescenzstrahlung 12, 12' zum Empfänger 10 führende Reflektionsumlenkeinrichtung 9 beinhaltet.
    Durch die einfache Umordnungsmoglichkeit an marktgängigen Geräten sind Veränderungen der eigentlichen Grundgerätespezifikationen durchführbar, so daß sich eine größere Bandbreite verschiedener Analysen im wesentlichen einheitlicher Grundgeräte durchführen läßt (siehe Fig. 1).

    Abstract translation: 实际上，这两个设备需要彼此相邻。 光度计的重新安装形成荧光计或反之亦然是复杂的。 这导致了两种类型的多个简单的对象绑定设备的开发。 因此，本发明的目的是指定一种物体保持器，其通过简单的操作或重新排列，在特定情况下实际上允许任何调查，与所使用的基本设备的类型无关。 根据本发明的解决方案设想一种构造为块单元2的物体保持器，其旨在接收灯泡6或测试条7，其配备有用于不同滤光器的插入件5，并且包含反射偏转装置9，该反射偏转装置9引导光学或荧光辐射 12,12'到接收机10.通过市售设备上的简单重新布置能力，可以对实际的基本设备规范进行改变，使得可以执行基本均匀的基本设备的不同分析的相对较大的带宽（ 参见图1）。

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