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公开(公告)号:US20230174950A1
公开(公告)日:2023-06-08
申请号:US17995114
申请日:2020-11-24
Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION , POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION
Inventor: Yong Kyun KIM , Dong-Woo CHO , Sun Ah NAM , Jin Won KIM , Jae Yeon LEE , Jae Yun KIM
CPC classification number: C12N5/0697 , A61K35/22 , C12N5/0686 , C12N2506/45 , C12N2513/00 , C12N2533/54 , C12N2533/90
Abstract: The present invention relates to a kidney organoid having a nephron-like structure and a production method therefor. A kidney organoid culture system using kidney dECM hydrogels according to the present invention induced the vascularization of the kidney organoid and the expression of podocytes, tubular transporters, and cilium genes, and has an effect of forming a more mature nephron-like structure. Therefore, the kidney organoid produced by the method of the present invention is an option for treating nephron loss through transplantation into humans, and is expected to be utilized as a kidney on a chip, which is an in vitro kidney model.
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公开(公告)号:US20230164002A1
公开(公告)日:2023-05-25
申请号:US17925183
申请日:2021-05-14
Inventor: Namyoon LEE , Hyowon LEE
IPC: H04L25/02
CPC classification number: H04L25/021 , H04L25/0204
Abstract: Disclosed are a user detection technique, and a method and apparatus for channel estimation in a wireless communication system supporting massive multiple-input multiple-output. The method comprises the steps of: receiving a superimposed signal including a transmission signal of at least one user equipment (UE) from among a plurality of user equipments, wherein each transmission signal includes a pilot signal of a corresponding user equipment; calculating a sample covariance matrix from the received superimposed signal by using the number of antennas of a base station and a pilot signal matrix of the at least one user equipment; calculating a likelihood function indicating the likelihood probability of the received superimposed signal, on the basis of the number of antennas of the base station and the received superimposed signal; detecting a user index set indicating whether or not the plurality of user equipments have transmitted signals, by using the calculated likelihood function and sample covariance matrix; and performing channel estimation of the at least one user equipment that is transmitting the signal, on the basis of the detected user index set.
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203.
公开(公告)号:US20230162727A1
公开(公告)日:2023-05-25
申请号:US17954185
申请日:2022-09-27
Inventor: Geun Bae LEE , Won Jun LEE
CPC classification number: G10L15/16 , G10L15/02 , G10L15/22 , G10L15/005
Abstract: A method for automatic multilingual speech recognition may comprise: recognizing input audio data by a speech recognizer; classifying the audio data by a speech language classifier; activating, by an output layer selector coupled to the speech recognizer, any one projection output layer of a plurality projection output layers respectively connected to the speech recognizer according to language classification information received from the speech language classifier, an output unit of the activated projection output layer being configured as several bytes; and recombining outputs output in a unit of the several bytes by the activated projection output layer, and outputting the recombined output as an automatic speech recognition result for the audio data.
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公开(公告)号:US11642662B2
公开(公告)日:2023-05-09
申请号:US17228874
申请日:2021-04-13
Inventor: Wonyong Choi , Shinbi Lee
IPC: B01J23/89 , C01B32/198 , B01J21/06 , B01J37/34 , C02F1/32 , C01B32/192 , B01J37/06 , B01J37/04 , B01J37/03 , B01J21/18 , C01B21/04 , B01J35/00 , B01J35/02 , C02F1/72 , C02F101/16
CPC classification number: B01J23/8926 , B01J21/063 , B01J21/185 , B01J35/004 , B01J35/0006 , B01J35/023 , B01J37/038 , B01J37/04 , B01J37/06 , B01J37/345 , C01B21/0422 , C01B32/192 , C01B32/198 , C02F1/32 , C02F1/725 , C01B2204/02 , C01P2004/04 , C02F2101/163 , C02F2305/08 , C02F2305/10
Abstract: Proposed are a photocatalyst, including titanium dioxide particles including titanium dioxide (TiO2), a carbon material located on all or part of the surface of the titanium dioxide particles and including at least one selected from the group consisting of graphene, reduced graphene oxide (rGO), and carbon nanotubes (CNTs), and bimetallic nanoparticles supported on the carbon material and including first metal nanoparticles and second metal nanoparticles, and a water treatment method using the same. In the photocatalyst and the water treatment method using the same, the photocatalyst including bimetallic nanoparticles and graphene oxide is prepared, thereby exhibiting high reduction efficiency and high selectivity to nitrogen gas even without the use of an external electron donor.
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公开(公告)号:US20230111780A1
公开(公告)日:2023-04-13
申请号:US17936385
申请日:2022-09-29
Applicant: POSTECH Research and Business Development Foundation , Konkuk University Industrial Cooperation Corp
Inventor: Hyeon Ji KIM , Je Hwan JANG , Won Il HAN , Joon Young KIM , Jin Ah JANG , Dong Woo CHO
Abstract: An embodiment of the present disclosure provides an extracellular matrix-based bioadhesive as an adhesive in the form of a composition including an extracellular matrix-containing hydrogel and a gelatin curing agent, wherein the extracellular matrix-containing hydrogel is gelatinized. Since the extracellular matrix-based bioadhesive according to an embodiment of the present disclosure has the same or similar rheological properties as gelatin, the bioadhesive has flowability at a temperature of 30° C. or higher and may be evenly and easily applied to a lesion site in the body. In addition, the extracellular matrix-based bioadhesive according to an embodiment of the present disclosure may adhere well to the lesion site because of a level of adhesive strength that is about 2 to 6 times higher than that of fibrin glue used as a commercial tissue adhesive. In addition, the extracellular matrix-based bioadhesive according to an embodiment of the present disclosure is based on a tissue-derived extracellular matrix, and thus includes a tissue-derived wound healing component or a tissue regeneration component, and may be used for wound healing or tissue regeneration in addition to bioadhesive applications.
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公开(公告)号:US20230110331A1
公开(公告)日:2023-04-13
申请号:US17958209
申请日:2022-09-30
Inventor: Dong-Pyo KIM , Gwang-Noh AHN
IPC: B01J19/00 , B01F35/221 , B01F33/301 , B01F23/40 , C07D239/95
Abstract: Proposed are an automated microreactor for effective optimization of a high-speed chemical reaction, and a method of optimizing a high-speed chemical reaction using the same. The automated microreactor includes a raw material supply unit including a plurality of flow rate controllers that supply a plurality of raw materials and control flow rates of the plurality of raw materials, an intermediate reaction unit including a plurality of micromixers for intermediate that generate a first mixture and a plurality of tubular reactors for intermediate that generate an intermediate product, an intermediate reaction control unit including a valve member, and a product reaction unit including a product micromixer that produces a second mixture and producing a product, through which optimal synthesis conditions (optimal temperature, flow rate, reaction volume and organolithium reagent type) can be achieved to obtain the highest yield in a short time.
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公开(公告)号:US20230102003A1
公开(公告)日:2023-03-30
申请号:US17842930
申请日:2022-06-17
Applicant: POSTECH Research and Business Development Foundation , RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY
Inventor: Gi-Ra YI , Pil Jin Yoo , Tae Hui Kang , Seung-Jea Lee , Jeong Hoon Yoon , Jun Hyuk Lee , Won Jang Cho
IPC: H01M10/0565 , H01M10/052
Abstract: Proposed are a non-aqueous freestanding ion conductive gel for application to an electrolyte of a lithium secondary battery and a preparation method thereof. The non-aqueous freestanding ion conductive gel including: a matrix including a hydrophobic polymer famed through polymerization of monomers having an unsaturated double-bond; a domain dispersed in the matrix and including a hydrophilic ionic liquid; and a surface active layer including an ionic liquid having surface activity, in which a portion of a hydrophobic segment in a chain of the ionic liquid having surface activity is positioned in the matrix, and a portion of a hydrophilic segment in the chain is positioned in the domain. The gel has high ionic conductivity, high lithium ion transference number, and excellent mechanical strength. The gel can be used as an electrolyte of a lithium
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208.
公开(公告)号:US20230089322A1
公开(公告)日:2023-03-23
申请号:US17751992
申请日:2022-05-24
Inventor: Dong-Pyo KIM , Gwang-Noh AHN
Abstract: Provided is a method of manufacturing a module structure for photomicro-reactors. The method of manufacturing a module structure for photomicro-reactors according to an aspect of the present invention, which is a method of manufacturing the module structure for photomicro-reactors inside which a reactant and a photocatalyst flow and photochemically react, includes mixing a polymer and a photoinitiator to prepare a photocurable resin, exposing one region of a surface of the photocurable resin to ultraviolet light to form a unit layer having a predetermined thickness, placing the photocurable resin on an upper side of the unit layer, and forming and stacking a plurality of the unit layers by repeatedly performing the forming of the unit layer and the placing of the photocurable resin to form the module structure.
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公开(公告)号:US11600911B2
公开(公告)日:2023-03-07
申请号:US17012863
申请日:2020-09-04
Inventor: Jong Min Kim , Dong Pil Park , Yun Seok Oh , Won Bin Hong
Abstract: An antenna device according to an embodiment of the present invention includes a dielectric layer, an upper electrode layer disposed on the dielectric layer and including a radiation pattern, a lower electrode layer disposed on the dielectric layer, and a bending connection portion integrally connected to the upper electrode layer and the lower electrode layer on the dielectric layer. An interconnection of a ground layer is implemented with high reliability by the bending connection portion.
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公开(公告)号:US20230061770A1
公开(公告)日:2023-03-02
申请号:US17833691
申请日:2022-06-06
Inventor: Banerjee WRTIAM , Hyun Sang HWANG , Seung Woo LEE
IPC: H01L45/00
Abstract: A two-terminal atom-based switching device having a fast operating speed and high durability and a manufacturing method thereof are disclosed. It is possible to reduce a forming voltage during positive voltage forming by forming an oxygen vacancy percolation path through negative voltage forming, which is first forming, and forming high binding energy and low formation energy between oxygen vacancies and metal ions implanted through positive voltage forming which is second forming after the negative voltage forming. Further, since a significant amount of metal ions implanted into the insulating layer through negative voltage application switching after the positive voltage forming is removed, the volatility of the two-terminal atom-based switching device may be improved, and a stuck-on failure phenomenon in the durability may be prevented.
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