Abstract:
A system and method are disclosed for configuring an integrated computational element (ICE) to measure a property of a sample of interest. The system includes an illumination source to provide a sample light which is reflected from or transmitted through a sample. A dispersive element disperses the sample light into wavelength portions. An intensity modulation device having an array of electronically controllable modulation elements is disclosed that forms a pattern which modulates the dispersed sample light. Collection optics focuses the modulated sample light on a detector, which generates a signal that correlates to a property of the sample. The electronically controllable modulation elements can be readily altered to conform to a different measurable property of a sample of interest as desired.
Abstract:
Die Erfindung betrifft eine Vorrichtung zur Aufnahme eines Absorptionsspektrums eines Fluids mit einer ersten Strahlungsquelle (1), die entlang eines ersten Strahlengangs (11) eine Strahlung in einem ersten Spektralbereich emittiert, mit einer in dem ersten Strahlengang (11) angeordneten ersten Messstrecke (5), entlang derer die Strahlung durch das Fluid tritt, mit einem in dem ersten Strahlengang (11) angeordneten durchstimmbaren Fabry-Perot Interferometer (7), das als ein verschiebbarer Bandpassfilter Strahlung in dem ersten Spektralbereich transmittieren kann, und mit einem ersten Detektor (9; 35) zur Messung der Intensität der Strahlung in dem ersten Spektralbereich. Erfindungsgemäß ist vorgesehen, dass die Vorrichtung ein erstes Etalon (3) zur spektralen Modulation der Strahlung aufweist, das in dem ersten Strahlengang (11) angeordnet ist und das in dem ersten Spektralbereich eine Mehrzahl von Transmissionsmaxima (17) aufweist, und dass das Fabry- Perot (7) dazu eingerichtet ist, dass das von dem Fabry-Perot Interferometer (7) gebildete Bandpassfilter derart über den ersten Spektralbereich verschoben werden kann, dass die spektrale Modulation der Strahlung durch das erste Etalon (3) als eine zeitliche Modulation der Intensität der Strahlung von dem ersten Detektor (9, 35) gemessen werden kann.
Abstract:
A method is provided comprising, obtaining an infrared (IR) spectrum of a Peripheral Blood Mononuclear Cells (PBMC) sample by analyzing the sample by infrared spectroscopy; and based on the infrared spectrum, generating an output indicative of the presence of a solid tumor or a pre-malignant condition. Other embodiments are also provided.
Abstract:
A method and an apparatus for carrying out a chemical-physical analysis, such as a spectroscopic analysis, an absorption analysis, a scattering analysis, etc. on one or more regions of a sample (11 ), provides prearranging a source (1 ) of a first electromagnetic radiation comprising a plurality of components with respective wavelength, prearranging a plurality of sites (9) distributed on a determined surface to emit the first radiation, arranging such surface facing a corresponding region of a sample (11 ) such that the whole surface thereof is attained by the first radiation, emitting the first radiation on the sample (11) thus causing the emission of a second radiation by the sample (11 ), which is analysed to associate an intensity of the second radiation to each region and wavelength. For each of the wavelength of the first radiation, a wavelength code is selected by which respective components of the first radiation are coded; the coded components are joined together to form the first electromagnetic radiation which is distributed in a plurality of radiation beams. Such beams are conveyed to respective emission sites (9), for each of which an emission site (9) code is selected, a radiation beam being codified by said code. A decoding of the of the second radiation produces a plurality of fractions, each fraction associated to a wavelength of the first radiation such that for each emission site (9) it is possible to instantaneously compare each fraction associated to a respective wavelength with a component of the first radiation having the same wavelength, the components of the first electromagnetic radiation being emitted simultaneously. The steps of wavelength coding and of site coding, and possibly also other coding steps may be earned out subsequently with respect to one another, or at the same time. The method and the apparatus allow reducing the time required to carry out said analysis.
Abstract:
The present invention discloses a flow cell optical detection system comprising a light source, a flow cell and a light detector, wherein the light detector is arranged in a separate detector unit that is arranged to be releasably attached to a detector interface, the detector interface being in optical communication with the light source and comprises optical connectors for optically connecting the flow cell and the detector unit in the light path from the light source, and wherein the flow cell is an interchangeable unit arranged to be held in position by the detector unit when attached to the detector interface.
Abstract:
A system and method for spectroscopic detection of a loss in a resonator cavity. The system comprises: a tunable laser source for generating a laser beam; a frequency locking system for either locking the frequency of the laser beam to a resonance of the resonator cavity or locking the length of the cavity to the frequency of the laser beam; a first modulation element for modulating the laser beam at a first modulation frequency to generate a modulated laser beam; an input coupler adapted for directing the modulated laser beam into the resonator cavity; a first directing element for directing a first portion of light reflected from the input coupler to a first photodetector to generate a first detected signal; and a first demodulator capable of demodulating the first modulation signal from the first detected signal to generate a first error signal which is a function of the loss in the resonator cavity.
Abstract:
The invention relates to a measuring device for optically determining the concentration of blood sugar and/or lactate in biological systems, comprising at least one IR radiation source (3), that radiates IR light on a volume (1) that is to examined, and at least one measuring detector (10) that detects light coming from the volume (1) that is to be examined in order to determine the concentration of blood sugar and/or lactate, also by laymen in a simple manner and anywhere. According to the invention, the IR light radiated on the volume (1) that is to be examined is supplied, prior to entry into the volume (1), to a reference detector.
Abstract:
Um die Konzentration von Blutzucker und/oder Laktat auch von Laien Vorort einfach durchzuführen, wird eine Messeinrichtung zur optischen Konzentrationsbestimmung von Blutzucker und/oder Laktat in biologischen Systemen mit wenigstens einer IR-Strahlenquelle, die IR-Licht auf ein zu untersuchendes Volumen strahlt, sowie mit wenigstens einem Messdetektor, der von dem zu untersuchenden Volumen ausgehendes Licht aufnimmt, vorgeschlagen, bei welcher das auf das zu untersuchende Volumen gestrahlte ER-Licht vor Eintritt in das Volumen einem Referenzdetektor zugeführt wird.
Abstract:
An apparatus for performing real-time analysis of a subterranean formation fluid includes a light source configured to transmit at least a sample signal through a sample of the subterranean formation fluid and a reference signal, at least one photodetector configured to continuously detect the sample and reference signals, and an electronics assembly configured to compensate for drift in the detected sample signal in real-time based on the value of the detected reference signal.
Abstract:
A system for determining an analyte concentration in a fluid sample (e.g., glucose) comprises a light source, a detector, and a central processing unit. The detector is adapted to receive spectral information corresponding to light returned from the fluid sample being analyzed and to convert the received spectral information into an electrical signal indicative of the received spectral information. The central processing unit is adapted to compare the electrical signal to an algorithm built upon correlation with the analyte in body fluid. The algorithm is adapted to convert the received spectral information into the analyte concentration in body fluid. Spectral information is delivered from the central processing unit to the light source and used to vary the intensity and timing of the light to improve the accuracy of conversion into analyte concentration.