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211.发明授权Chemical-analysis device integrated with metallic-nanofinger device for chemical sensing 有权化学分析装置与金属纳米装置集成，用于化学传感公开(公告)号：US09279767B2
公开(公告)日：2016-03-08
申请号：US13879255
申请日：2010-10-20
Applicant: Zhiyong Li , R. Stanley Williams
Inventor： Zhiyong Li , R. Stanley Williams
CPC classification number: G01N21/6428 , G01N21/648 , G01N21/658 , G01N33/54373
Abstract: A chemical-analysis device integrated with a metallic-nanofinger device for chemical sensing. The chemical-analysis device includes a metallic-nanofinger device, and a platform. The metallic-nanofinger device includes a substrate, and a plurality of nanofingers coupled with the substrate. A nanofinger of the plurality includes a flexible column, and a metallic cap coupled to an apex of the flexible column. At least the nanofinger and a second nanofinger of the plurality of nanofingers are to self-arrange into a close-packed configuration with at least one analyte molecule. A morphology of the metallic cap is to generate a shifted plasmonic-resonance peak associated with amplified luminescence from the analyte molecule. A method for using, and a chemical-analysis apparatus including the chemical-analysis device are also provided.
Abstract translation: 与用于化学感测的金属纳米酮装置集成的化学分析装置。 化学分析装置包括金属纳米装置和平台。 金属纳米装置包括衬底和与衬底耦合的多个纳米器件。 多个纳米针板包括柔性柱和联接到柔性柱的顶点的金属帽。 至少纳米角蛋白和多个纳米针的第二纳米角键将与至少一个分析物分子自组织成紧密堆积的构型。 金属盖的形态是产生与来自分析物分子的放大发光相关的移位等离子体共振峰。 还提供了一种使用方法和包括该化学分析装置的化学分析装置。
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公开(公告)号：US09274058B2
公开(公告)日：2016-03-01
申请号：US13879245
申请日：2010-10-20
Applicant: Zhiyong Li , R. Stanley Williams
Inventor： Zhiyong Li , R. Stanley Williams
CPC classification number: G01N21/658 , G01N21/648
Abstract: A metallic-nanofinger device for chemical sensing. The device includes a substrate, and a plurality of nanofingers. A nanofinger includes a flexible column, and a metallic cap coupled to an apex of the flexible column. At least the nanofinger and a second nanofinger are to self-arrange into a close-packed configuration with at least one analyte molecule disposed between at least the metallic cap and a second metallic cap of respective nanofinger and second nanofinger. A morphology of the metallic cap is to generate a shifted plasmonic-resonance peak associated with amplified luminescence from the analyte molecule. A coating encapsulating the metallic cap to respond upon exposure to a liquid, and a chemical-sensing chip including the metallic-nanofinger device are also provided.
Abstract translation: 用于化学感应的金属纳米膜装置。 该装置包括基板和多个纳米装置。 纳米针框包括柔性柱和与柔性柱的顶点相连的金属帽。 至少纳米酮和第二纳米酮将自排列成紧密堆积的构型，其中至少一个分析物分子设置在至少金属盖和相应的纳芬酮和第二纳米酮之间的第二金属盖之间。 金属帽的形态是产生与来自分析物分子的放大发光相关的移位等离子体共振峰。 还提供了包封金属盖以在暴露于液体时响应的涂层，以及包括金属纳米酮装置的化学感测芯片。
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213.发明授权Self-arranging, luminescence-enhancement device for surface-enhanced luminescence 有权用于表面增强发光的自排列，发光增强器件公开(公告)号：US09244015B2
公开(公告)日：2016-01-26
申请号：US13636784
申请日：2010-04-20
Applicant: Zhiyong Li , Min Hu , Fung Suong Ou , Wei Wu
Inventor： Zhiyong Li , Min Hu , Fung Suong Ou , Wei Wu
CPC classification number: G01N21/658 , G01N21/648
Abstract: A self-arranging, luminescence-enhancement device 101 for surface-enhanced luminescence. The self-arranging, luminescence-enhancement device 101 for surface-enhanced luminescence includes a substrate 110, and a plurality 120 of flexible columnar structures. A flexible columnar structure 120-1 of the plurality 120 includes a flexible column 120-1A, and a metallic cap 120-1B coupled to the apex 120-1 C of the flexible column 120-1A. At least the flexible columnar structure 120-1 and a second flexible columnar structure 120-2 are configured to self-arrange into a close-packed configuration with at least one molecule 220-1 disposed between at least the metallic cap 120-1B and a second metallic cap 120-2B of respective flexible columnar structure 120-1 and second flexible columnar structure 120-2.
Abstract translation: 用于表面增强发光的自配置发光增强装置101。 用于表面增强发光的自配置发光增强装置101包括基板110和多个120个柔性柱状结构。 多个120的柔性柱状结构120-1包括柔性柱120-1A以及耦合到柔性柱120-1A的顶点120-1C的金属盖120-1B。 至少柔性柱状结构120-1和第二柔性柱状结构120-2构造成自配置成紧密堆积构造，其中至少一个分子220-1设置在至少金属盖120-1B和 各个柔性柱状结构120-1的第二金属盖120-2B和第二柔性柱状结构120-2。
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公开(公告)号：US20150173656A1
公开(公告)日：2015-06-25
申请号：US14406601
申请日：2012-07-29
Applicant: Steven Barcelo , Zhiyong Li , Ansoon Kim , Gary Gibson
Inventor： Steven Barcelo , Zhiyong Li , Ansoon Kim , Gary Gibson
IPC: A61B5/1459 , A61B5/00
CPC classification number: A61B5/1459 , A61B5/0075 , A61B5/6862 , G01N21/658
Abstract: An implantable nanosensor includes a stent to be implanted inside a fluid conduit. The stent has a well in a surface of the stent. The implantable nanosensor further includes a nanoscale-patterned sensing substrate disposed in the well. The nanoscale-patterned sensing substrate is to produce an optical scattering response signal indicative of a presence of an analyte in a fluid carried by the fluid conduit when interrogated by an optical stimulus signal.
Abstract translation: 可植入纳米传感器包括待植入流体导管内的支架。 支架在支架表面有一个井。 可植入纳米传感器还包括设置在井中的纳米级图案感测基片。 纳米级图案化感测衬底将产生光学散射响应信号，该信号指示由光学刺激信号询问时由流体导管携带的流体中的分析物的存在。
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公开(公告)号：US20150116706A1
公开(公告)日：2015-04-30
申请号：US14394287
申请日：2012-04-24
Applicant: Steven Barcelo , Zhiyong Li , Alexandre M. Bratkovski , Ansoon Kim
Inventor： Steven Barcelo , Zhiyong Li , Alexandre M. Bratkovski , Ansoon Kim
IPC: G01N21/65
CPC classification number: G01N21/658 , B82Y15/00 , G01N2201/06113 , Y10S977/954
Abstract: An apparatus for performing a sensing application includes a reservoir to contain a solution, a dispenser to dispense the solution from the reservoir, and a substrate having a plurality of nano-fingers positioned to receive the dispensed solution, in which the plurality of nano-fingers are flexible, such that the plurality of nano-fingers are configurable with respect to each other. The apparatus also includes an illumination source to illuminate the received solution, an analyte introduced around the plurality of nano-fingers, and the plurality of nano-fingers, in which light is to be emitted from the analyte in response to being illuminated. The apparatus further includes a detector to detect the light emitted from the analyte.
Abstract translation: 用于执行感测应用的装置包括容纳溶液的储存器，用于从储存器分配溶液的分配器以及具有多个纳米手指的基板，该多个纳米手指定位成接收分配的溶液，其中多个纳米手指 是柔性的，使得多个纳米手指可相对于彼此配置。 所述装置还包括照亮所接收的溶液的照明源，围绕所述多个纳米手指引入的分析物和所述多个纳米手指，其中光将响应于被照亮从分析物发射。 该装置还包括检测器，用于检测从分析物发射的光。
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Patent Agency Ranking
公开(公告)号：US09019495B2
公开(公告)日：2015-04-28
申请号：US13563362
申请日：2012-07-31
Applicant: Ansoon Kim , Zhiyong Li , Steven J. Barcelo , Zhang-Lin Zhou , Gary Gibson
Inventor： Ansoon Kim , Zhiyong Li , Steven J. Barcelo , Zhang-Lin Zhou , Gary Gibson
CPC classification number: G01N21/658 , G01N2021/775 , Y10T29/49826
Abstract: According to an example, an apparatus for performing spectroscopy includes a structure having an opening. The apparatus also includes a plurality of surface-enhanced Raman spectroscopy (SERS) elements positioned within the structure and a porous membrane covering the opening and the plurality of SERS elements. The porous membrane is to allow a predetermined analyte to reach the SERS elements while substantially preventing other analytes from reaching the SERS elements.
Abstract translation: 根据示例，用于执行光谱的装置包括具有开口的结构。 该装置还包括位于结构内的多个表面增强拉曼光谱（SERS）元件和覆盖该开口的多孔膜和多个SERS元件。 多孔膜是允许预定的分析物到达SERS元素，同时基本上防止其它分析物到达SERS元件。
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公开(公告)号：US08842265B2
公开(公告)日：2014-09-23
申请号：US13090016
申请日：2011-04-19
Applicant: David A. Fattal , Raymond G. Beausoieil , Zhiyong Li
Inventor： David A. Fattal , Raymond G. Beausoieil , Zhiyong Li
CPC classification number: B82Y20/00 , B29D11/00346 , B29D11/0074 , G02B5/1809 , G02B5/1828
Abstract: A configurable grating based on collapsing nano-fingers includes a substrate; and a plurality of bendable nano-fingers supported on the substrate. The nano-fingers may be formed in a regular first array and the nano-fingers may be formed in a spacing that, upon closing at their tops, forms a second array to act as an optical grating or a diagnostic tool. A method of fabricating a configurable optical grating based on collapsing nano-fingers is also disclosed, as well as a method of determining an open or closed state for a plurality of nano-fingers.
Abstract translation: 基于塌陷纳米指的可配置光栅包括基底; 以及支撑在基板上的多个可弯曲的纳米手指。 纳米指可以形成为规则的第一阵列，并且纳米指可以以间隔形成，在其顶部关闭时，形成第二阵列以用作光栅或诊断工具。 还公开了一种基于塌陷纳米手指制造可配置光栅的方法，以及确定多个纳米手指的打开或关闭状态的方法。
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公开(公告)号：US08665432B2
公开(公告)日：2014-03-04
申请号：US12915148
申请日：2010-10-29
Applicant: Min Hu , Michael Josef Stuke , Zhiyong Li , Wei Wu , Fung Suong Ou , Shih-Yuan Wang , Lars Helge Thylen
Inventor： Min Hu , Michael Josef Stuke , Zhiyong Li , Wei Wu , Fung Suong Ou , Shih-Yuan Wang , Lars Helge Thylen
IPC: G01N21/65
CPC classification number: G01J3/44 , G01N21/658
Abstract: An apparatus for performing surface enhanced Raman spectroscopy (SERS) includes a substrate and a plurality of nano-pillars, each of the plurality of nano-pillars having a first end attached to the substrate, a second end located distally from the substrate, and a body portion extending between the first end and the second end, in which the plurality of nano-pillars are arranged in an array on the substrate, and in which each of the plurality of nano-pillars is formed of a polymer material that is functionalized to expand in the presence of a fluid to cause gaps between the plurality of nano-pillars to shrink when the fluid is supplied onto the nano-pillars.
Abstract translation: 用于进行表面增强拉曼光谱（SERS）的设备包括基底和多个纳米柱，多个纳米柱中的每一个具有连接到基底的第一端，位于远离基底的第二端，以及 主体部分在所述第一端和所述第二端之间延伸，其中所述多个纳米柱以阵列布置在所述基底上，并且所述多个纳米柱中的每一个由聚合物材料形成，所述聚合物材料被官能化为 在存在流体的情况下膨胀，以便当将流体供应到纳米支柱上时，使多个纳米柱之间的间隙收缩。
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公开(公告)号：US20140036263A1
公开(公告)日：2014-02-06
申请号：US13563362
申请日：2012-07-31
Applicant: Ansoon KIM , Zhiyong Li , Steven J. Barcelo , Zhang-Lin Zhou , Gary Gibson
Inventor： Ansoon KIM , Zhiyong Li , Steven J. Barcelo , Zhang-Lin Zhou , Gary Gibson
CPC classification number: G01N21/658 , G01N2021/775 , Y10T29/49826
Abstract: According to an example, an apparatus for performing spectroscopy includes a structure having an opening. The apparatus also includes a plurality of surface-enhanced Raman spectroscopy (SERS) elements positioned within the structure and a porous membrane covering the opening and the plurality of SERS elements. The porous membrane is to allow a predetermined analyte to reach the SERS elements while substantially preventing other analytes from reaching the SERS elements.
Abstract translation: 根据示例，用于执行光谱的装置包括具有开口的结构。 该装置还包括位于结构内的多个表面增强拉曼光谱（SERS）元件和覆盖该开口的多孔膜和多个SERS元件。 多孔膜是允许预定的分析物到达SERS元素，同时基本上防止其它分析物到达SERS元件。
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220.发明申请ELECTRONIC AND PLASMONIC ENHANCEMENT FOR SURFACE ENHANCED RAMAN SPECTROSCOPY 审中-公开表面增强拉曼光谱的电子和等离子体增强公开(公告)号：US20140036262A1
公开(公告)日：2014-02-06
申请号：US13562567
申请日：2012-07-31
Applicant: Shih-Yuan Wang , Gary Gibson , Zhiyong Li , Alexandre M. Bratkovski , Huei Pei Kuo , Zhang-Lin Zhou , R Stanley Williams
Inventor： Shih-Yuan Wang , Gary Gibson , Zhiyong Li , Alexandre M. Bratkovski , Huei Pei Kuo , Zhang-Lin Zhou , R Stanley Williams
IPC: G01J3/44
CPC classification number: G01N21/658
Abstract: An apparatus for surface enhanced Raman spectroscopy includes a substrate, a nanostructure and a plasmonic material. The nanostructure and the plasmonic material are integrated together to provide electronic and plasmonic enhancement to a Raman signal produced by electromagnetic radiation scattering from an analyte.
Abstract translation: 用于表面增强拉曼光谱的装置包括底物，纳米结构和等离子体激元材料。 将纳米结构和等离子体激元材料集成在一起，以对由分析物的电磁辐射散射产生的拉曼信号提供电子和等离子体增强。
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