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221.发明授权公开(公告)号：US09443705B2
公开(公告)日：2016-09-13
申请号：US14851401
申请日：2015-09-11
Applicant: Korea Basic Science Institute
Inventor： Seung Yong Kim , Mo Yang , Hyun Sik Kim
CPC classification number: H01J49/0022 , H01J49/022 , H01J49/427 , H03F3/19 , H03F2200/451
Abstract: Provided is a multiple frequency Radio Frequency (RF) amplifier. The multiple frequency RF amplifier includes a waveform generation circuit configured to generate an RF signal by amplitude and frequency-modulating a reference waveform signal, a drive amplifier circuit configured to drive-amplify the RF signal, and a power amplifier circuit configured to generate a multiple frequency RF voltage signal through a power amplification of the drive-amplified RF signal and output the multiple frequency RF voltage signal to an ion trap for a mass spectrometry.
Abstract translation: 提供了一种多频射频（RF）放大器。 多频RF放大器包括：波形发生电路，被配置为通过幅度产生RF信号并对参考波形信号进行频率调制;驱动放大器电路，被配置为驱动放大RF信号;以及功率放大器电路，被配置为产生多个 通过驱动放大的RF信号的功率放大来输出频率RF电压信号，并将多频RF电压信号输出到用于质谱的离子阱。
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222.发明授权Bioinformatics platform for high-throughput identification and quantification of N—glycopeptide 有权用于高通量鉴定和定量的N-糖肽的生物信息学平台公开(公告)号：US09436797B2
公开(公告)日：2016-09-06
申请号：US13884233
申请日：2013-01-22
Applicant: Korea Basic Science Institute
Inventor： Gun Wook Park , Jong Shin Yoo , Jin Young Kim , Ju Yeon Lee , Hyun Kyoung Lee , Hyun Joo An , Jae-Han Kim
CPC classification number: G06F19/16 , C12Q1/37 , G01N30/86 , G01N33/6848 , G01N2030/8813 , G01N2030/8831 , G01N2400/00 , G01N2440/38 , G01N2560/00 , G01N2570/00 , H01J49/0027 , H01J49/0036 , H01J49/004
Abstract: The present invention relates to a more efficient and accurate method for the identification and quantification of comparatively low abundant glycopeptides, compared with general peptides, using mass spectrum obtained by using high resolution mass spectrometer. Therefore, the method of the present invention can be effectively used for the techniques for identification of biotherapeutics and diagnosis of cancer or disease by screening glycopeptide, the disease marker (Biomarker), from various samples.
Abstract translation: 本发明涉及使用通过使用高分辨率质谱仪获得的质谱，与一般肽相比，用于鉴定和定量相对低丰度糖肽的更有效和准确的方法。 因此，通过从各种样品中筛选糖肽（疾病标记物（Biomarker）），本发明的方法可以有效地用于识别生物治疗剂和癌症或疾病的诊断技术。
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223.发明申请METHOD OF PREPARING MONOATOMIC LAYER BLACK PHOSPHOROUS BY IRRADIATING ULTRASOUND 有权通过辐射超声波制备单层黑色磷光体的方法公开(公告)号：US20160126323A1
公开(公告)日：2016-05-05
申请号：US14879734
申请日：2015-10-09
Applicant: KOREA BASIC SCIENCE INSTITUTE
Inventor： Hyun-Uk LEE , Jou-Hahn LEE , Soon-Chang LEE
Abstract: A method of preparing monoatomic layer black phosphorous by irradiating an ultrasound includes: putting black phosphorus into a solvent and irradiating the ultrasound; recovering a solution from a solution to which the ultrasound is irradiated; and collecting black phosphorus remaining after the solution has been recovered, putting the black phosphorus into a solvent, irradiating the ultrasound, and recovering a solution.
Abstract translation: 通过照射超声波制备单原子黑色磷的方法包括：将黑磷放入溶剂中并照射超声波; 从超声波照射的溶液中回收溶液; 并收集溶液后残留的黑磷，将黑磷放入溶剂中，照射超声波，并回收溶液。
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公开(公告)号：US09322071B2
公开(公告)日：2016-04-26
申请号：US14499801
申请日：2014-09-29
Inventor： Joseph Kwon , Jong-Soon Choi , Duwoon Kim , Hee-Min Lee
CPC classification number: C12Q1/701 , C12N7/02 , C12N2770/16011 , C12N2770/32411 , C12Q1/706 , Y02A50/54
Abstract: Disclosed is an economic method for concentrating virus and detecting virus, such that virus in a sample solution having low virus concentration can be concentrated with high efficiency within a short time. Particularly, the method comprising the steps of: (A) adding Concanavalin A (Con A) to a sample solution containing a virus, and reacting the added Concanavalin A with the virus in the sample solution to form a virus-Concanavalin A conjugate; and (B) separating the virus-Concanavalin A conjugate from the sample solution.
Abstract translation: 公开了一种用于浓缩病毒和检测病毒的经济方法，使得可以在短时间内以高效率浓缩具有低病毒浓度的样品溶液中的病毒。 特别地，该方法包括以下步骤：（A）将伴刀豆球蛋白A（Con A）加入到含有病毒的样品溶液中，并将加入的伴刀豆球蛋白A与病毒在样品溶液中反应，形成病毒 - 伴刀豆球蛋白A缀合物; 和（B）从样品溶液中分离病毒 - 伴刀豆球蛋白A缀合物。
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225.发明授权Lens for electron capture dissociation, Fourier transform ion cyclotron resonance mass spectrometer comprising the same and method for improving signal of Fourier transform ion cyclotron resonance mass spectrometer 有权用于电子捕获离解的透镜，包含相同的傅里叶变换离子回旋共振质谱仪和用于改进傅里叶变换离子回旋共振质谱仪的信号的方法公开(公告)号：US09129788B2
公开(公告)日：2015-09-08
申请号：US14351524
申请日：2012-10-10
Applicant: KOREA BASIC SCIENCE INSTITUTE
Inventor： Myoung Choul Choi , Sang Hwan Choi , Se Gyu Lee , Jeong Min Lee
CPC classification number: H01J49/067 , H01J49/0027 , H01J49/0054 , H01J49/062 , H01J49/38
Abstract: A lens for electron capture dissociation may include: a first electrode and a second electrode spaced apart from each other and arranged along a first direction; and a third electrode and a fourth electrode spaced apart from each other and arranged along a second direction perpendicular to the first direction. The first electrode and the second electrode may be disposed in a space in which a magnetic field is formed in the first direction and trap electrons. The third electrode and the fourth electrode may be in the form of a flat plate and may apply an electric field to the trapped electrons in the second direction.
Abstract translation: 用于电子捕获解离的透镜可以包括：第一电极和彼此间隔开并沿着第一方向布置的第二电极; 以及与第一方向垂直的第二方向配置的第三电极和第四电极。 第一电极和第二电极可以设置在其中在第一方向上形成磁场并捕获电子的空间中。 第三电极和第四电极可以是平板的形式，并且可以在第二方向上对捕获的电子施加电场。
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Patent Agency Ranking
公开(公告)号：US20150187543A1
公开(公告)日：2015-07-02
申请号：US14409357
申请日：2013-12-06
Applicant: KOREA BASIC SCIENCE INSTITUTE
Inventor： Dong Chan Seok , Yong Ho Jung , Hyun Young Jeong
IPC: H01J37/32
CPC classification number: H01J37/32568 , B01J19/088 , B01J2219/0835 , B01J2219/0879 , H01J37/32348 , H05H1/48 , H05H2001/2412
Abstract: A powder plasma processing apparatus is disclosed. The powder plasma processing apparatus includes: a chamber configured to perform plasma processing on a powder; a powder supply unit disposed in an upper portion of the chamber; and a plurality of plate-like surface discharge plasma modules disposed below the powder supply unit and positioned within the chamber, wherein surfaces of the surface discharge plasma modules are spaced apart from each other. According to the powder plasma processing apparatus, the powder can be uniformly processed, and the time that the powder spends in contact with the plasma can be controlled, thereby allowing efficient powder processing to be performed.
Abstract translation: 公开了一种粉末等离子体处理装置。 粉末等离子体处理装置包括：室，被配置为对粉末进行等离子体处理; 设置在所述室的上部的粉末供给单元; 以及多个板状表面放电等离子体模块，其设置在所述粉末供给单元的下方并且位于所述室内，其中所述表面放电等离子体模块的表面彼此间隔开。 根据粉末等离子体处理装置，可以均匀地加工粉末，并且可以控制粉末与等离子体接触的时间，从而实现有效的粉末处理。
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227.发明申请Bioinformatics Platform for High-Throughput Identification and Quantification of N--Glycopeptide 有权用于高通量鉴定和定量的N-糖肽的生物信息学平台公开(公告)号：US20150186595A1
公开(公告)日：2015-07-02
申请号：US13884233
申请日：2013-01-22
Applicant: Korea Basic Science Institute
Inventor： Gun Wook Park , Jong Shin Yoo , Jin Young Kim , Ju Yeon Lee , Hyun Kyoung Lee , Hyun Joo An , Jae-Han Kim
CPC classification number: G06F19/16 , C12Q1/37 , G01N30/86 , G01N33/6848 , G01N2030/8813 , G01N2030/8831 , G01N2400/00 , G01N2440/38 , G01N2560/00 , G01N2570/00 , H01J49/0027 , H01J49/0036 , H01J49/004
Abstract: The present invention relates to a more efficient and accurate method for the identification and quantification of comparatively low abundant glycopeptides, compared with general peptides, using mass spectrum obtained by using high resolution mass spectrometer. Therefore, the method of the present invention can be effectively used for the techniques for identification of biotherapeutics and diagnosis of cancer or disease by screening glycopeptide, the disease marker (Biomarker), from various samples.
Abstract translation: 本发明涉及使用通过使用高分辨率质谱仪获得的质谱，与一般肽相比，用于鉴定和定量相对低丰度糖肽的更有效和准确的方法。 因此，通过从各种样品中筛选糖肽（疾病标记物（Biomarker）），本发明的方法可以有效地用于识别生物治疗剂和癌症或疾病的诊断技术。
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公开(公告)号：US20150168359A1
公开(公告)日：2015-06-18
申请号：US14132108
申请日：2013-12-18
Applicant: Korea Basic Science Institute
Inventor： Sanggoo KIM , Sung-Min LIM
IPC: G01N30/60
CPC classification number: G01N30/6095 , G01N30/06 , G01N2030/067
Abstract: Provided is a derivatization reaction gas chromatographic chip including: an analysis solution inlet allowing an analysis solution containing an analysis target to be introduced therethrough; a derivative inlet allowing a reaction solution containing a derivative chemically reacting with the analysis target to be introduced therethrough; a guide channel connecting one end of a first micro-channel to each of the analysis solution inlet and the derivative inlet; the first micro-channel in which a fluid flows and the analysis target in the fluid is vaporized; a first outlet connected to the other end of the first micro-channel; a gas phase inlet communicating with the first outlet; a second micro-channel having one end connected to the gas phase inlet and having a stationary phase formed therein; and a second outlet connected to the other end of the second micro-channel.
Abstract translation: 提供了一种衍生化反应气相色谱芯片，其包括：允许通过其分析引入含有分析对象的分析溶液的分析溶液入口; 允许将含有与分析对象化学反应的衍生物的反应溶液引入其中的导入入口; 引导通道，其将第一微通道的一端连接到分析溶液入口和衍生入口中的每一个; 流体流动的第一微通道和流体中的分析目标被蒸发; 第一出口，连接到第一微通道的另一端; 与第一出口连通的气相入口; 第二微通道，其一端连接到气相入口并且具有形成在其中的固定相; 以及连接到第二微通道另一端的第二出口。
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229.发明申请PREPARING METHOD OF AG NANO-PARTICLE AND HYDROPHOBIC SPHERICAL AG NANO-PARTICLE PREPARED USING THE SAME 有权使用其制备的AG纳米颗粒和疏水性球形AG纳米颗粒的制备方法公开(公告)号：US20150132595A1
公开(公告)日：2015-05-14
申请号：US14176357
申请日：2014-02-10
Applicant: Korea Basic Science Institute
Inventor： Gaehang LEE , Yeon Suk CHOI , Doo Ri BAE
IPC: C07F1/00
CPC classification number: C07F1/10 , B22F1/0044 , B22F1/0048 , B22F9/24 , Y10T428/12
Abstract: Provided is a preparing method of an Ag nano-particle for mass-producing Ag nano-particles, the method including: performing a first reaction of a reaction solution containing an Ag precursor and oleylamine at a set first temperature T1; performing a second reaction of the reaction solution at a second temperature T2 set so as to be higher than the first temperature; and obtaining a reactant from the reaction solution, wherein at least one of the first and second reactions is performed in a state in which the reaction solution is not stirred.
Abstract translation: 本发明提供一种用于大量生产Ag纳米颗粒的Ag纳米颗粒的制备方法，该方法包括：在设定的第一温度T1下进行含有Ag前体和油胺的反应溶液的第一次反应; 在设定为高于第一温度的第二温度T2下进行反应溶液的第二反应; 从所述反应溶液中获得反应物，其中所述第一反应和所述第二反应中的至少一个在所述反应溶液不被搅拌的状态下进行。
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230.发明申请CRYOPROBE USING CLOSED GAS LOOP FOR NUCLEAR MAGNETIC RESONANCE APPARATUS 有权用于核磁共振装置的封闭气体循环的CRYOPROBE公开(公告)号：US20150111751A1
公开(公告)日：2015-04-23
申请号：US14107164
申请日：2013-12-16
Applicant: KOREA BASIC SCIENCE INSTITUTE
Inventor： Yeon Suk Choi , Seung Young Park , Sang Gap Lee
IPC: G01R33/34 , G01R33/3815
CPC classification number: G01R33/3403 , G01R33/307 , G01R33/31
Abstract: Provided is a cryoprobe using a closed gas loop for a nuclear magnetic resonance apparatus, including: superconducting magnets providing a magnetic field; a rotor rotatably disposed between the superconducting magnets in the state of a sample being put therein, the rotor being rotated by a driving gas; a coil configured to generate a nuclear magnetic resonance spectrum according to a resonance phenomenon of the sample by applying a radio frequency to the rotor; and a gas loop configured to cool the driving gas in a cryogenic condition while circulating it in a closed-loop condition and to supply the driving gas to the rotor, wherein the gas loop supplies the driving gas to the rotor while cooling it in a cryogenic condition, thereby rotating the rotor.
Abstract translation: 提供了一种使用用于核磁共振设备的封闭气体回路的冷冻探头，包括：提供磁场的超导磁体; 可转动地设置在超导磁体之间的转子，其中放置有样品的状态，转子由驱动气体旋转; 构造成通过向转子施加射频而根据样品的共振现象生成核磁共振谱的线圈; 以及气体回路，其构造成在低温条件下冷却驱动气体，同时在闭环状态下循环驱动气体并将驱动气体供应到转子，其中气体回路将驱动气体供应到转子，同时在低温 从而使转子旋转。
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