Abstract:
An automatic focus control apparatus includes a light detector, which receives light reflected by a surface of a wafer and generates a light reception signal based on the received signal, a controller, which generates a driving signal, the driving signal being one of a first signal and a second signal, the driving signal indicating whether to perform automatic focus control based on the light reception signal, a focus error corrector, which generates a focus error correction signal based on the driving signal, and a stage driver, which displaces a wafer stage supporting the wafer by adjusting the z-axis position of the wafer stage based on the focus error correcting signal if the driving signal is the first signal, and maintains the z-axis position of the wafer stage based on the focus error correction signal if the driving signal is the second signal.
Abstract:
The present invention relates to a method for controlling a spectrometer for analyzing a product, the spectrometer including a light source including several light-emitting diodes having respective emission spectra covering in combination an analysis wavelength band, the method including steps of: supplying at least one of the light-emitting diodes with a supply current to switch it on, measuring a light intensity emitted by the light source by measuring a current at a terminal of at least another of the light-emitting diodes maintained off, determining, according to each light intensity measurement, a setpoint value of the supply current of each diode that is on, and regulating the supply current of each diode that is on so that it corresponds to the setpoint value.
Abstract:
A method and system for correcting the effect of intensity fluctuations of the transmitted light in an absorption spectroscopy system used for the detection or measurement of chemical species in a medium, whereby one or more modulation bursts are imposed onto a light beam that passes through the medium. This burst signal may be obtained by modulating the bias current of a tunable diode laser, and the modulation burst signal may be optimally at the second harmonic of the modulation frequency of a wavelength modulated beam to allow usage of the same signal path processing used for the spectroscopic detection of the measurand for a second harmonic detection system. The burst signal can be controlled using a smooth window function to minimise the effects of non-linear perturbations that are inherent in tunable diode laser wavelength modulation spectroscopy systems, of optical interference fringes (etalons) and of the residual light absorption by background chemical species or the measurand at the wavelength coinciding with the modulation burst.
Abstract:
Methods and apparatus are provided for determining weight percent of solids in a suspension using Raman spectroscopy. The methods can be utilized to acquire Raman spectral data from the suspension and to determine weight percent of solids in a process being carried out, for example, in a vessel, without the need to remove samples for analysis. The weight percent of the solids can be determined with a desired accuracy in a relatively short time, typically 10 minutes or less. The acquired Raman spectral data may be processed by chemometric software using, for example, a partial least squares algorithm and data pretreatment to provide a predicted value of weight percent solids. In some embodiments, the invention is used to determine the weight percent of microparticles of a diketopiperazine in an aqueous solution.
Abstract:
An image processing apparatus includes: an interface unit configured to input an image signal from an imaging apparatus that exposes a specimen dyed with a fluorescent dye to excitation light and images fluorescence by a color imaging element; and a color correction circuit configured to retain information on a percentage of each of a component of a second color and a component of a third color with respect to a component of a first color corresponding to the excitation light in the image signal, which is determined in advance based on color filter spectral characteristics of the color imaging element, and reduce each of an amount corresponding to the percentage of the component of the second color and an amount corresponding to the percentage of the component of the third color from the input image signal.
Abstract:
Interferometric focusing (IF), rather than conventional geometric focusing, of excitation light onto a guide-star that is embedded deeply in tissue, increases its fluorescence intensity. The method can extend the depth of wavefront measurement and improve correction inside of tissues because of its ability to suppress both scattering of diffuse light and aberration of ballistic light. The results showed more than two times improvement in SNR and RMS error of the wavefront measurement. Although only ballistic light in the excitation path is corrected, the intensity after wavefront correction increased by 1.5 times. When applying IF to a two-photon microscope with a near infra-red laser, this method would further extend the measurement depth and achieve high SNR for the wavefront sensor.
Abstract:
A made-to-order system for cosmetics (10) includes: color detection apparatus (12) for detecting a color of a detection object; input apparatus for inputting a color of a cosmetic to be prepared; blend ratio setting apparatus (14) for generating a blend ratio for preparing a cosmetic having the color that is input to the input apparatus, from a plurality of kinds of cosmetic compositions; and a cosmetic preparation apparatus (20) that prepares the cosmetic by discharging and mixing the plurality of kinds of cosmetic compositions by means of respective positive displacement pumps such that the blend ratio generated by the blend ratio setting apparatus (14) is achieved.
Abstract:
A light deflection detection module with a detection stage, a surface light source, at least two scanning cameras and a standard surface is provided. The detection stage is utilized for supporting an object. The surface light source is disposed above the detection stage, and emits a planar light to the detection stage. The at least two scanning cameras are disposed opposite the surface light source. The standard surface is disposed adjacent to the detection stage. When the surface light source emits the planar light to the detection stage, the planar light will be reflected by the surface of the object and the standard surface first, and then received by the at least two scanning cameras. A processor will perform a numerical analysis on the reflected planar light to obtain the detection data and to make the error correction.
Abstract:
Interferometric focusing (IF), rather than conventional geometric focusing, of excitation light onto a guide-star that is embedded deeply in tissue, increases its fluorescence intensity. The method can extend the depth of wavefront measurement and improve correction inside of tissues because of its ability to suppress both scattering of diffuse light and aberration of ballistic light. The results showed more than two times improvement in SNR and RMS error of the wavefront measurement. Although only ballistic light in the excitation path is corrected, the intensity after wavefront correction increased by 1.5 times. When applying IF to a two-photon microscope with a near infra-red laser, this method would further extend the measurement depth and achieve high SNR for the wavefront sensor.
Abstract:
Techniques are disclosed relating to analysis and reduction of crosstalk between signals. These techniques may be applicable in many fields, such as single-tube PCR or DNA melt analysis, PCR or melt data from neighboring wells of a multi-well plate, capillary electrophoresis data (e.g., DNA sequencing), gas chromatography, multispectral imaging, dual-color fluorescence correlation spectrometry, electrical crosstalk, etc. According to one embodiment, crosstalk between fluorescence signals from different species may be determined based on a correlation between the time derivatives of the fluorescence signals from the fluorescent species.