公开(公告)号：WO1990001896A1

公开(公告)日：1990-03-08

申请号：PCT/US1989003664

申请日：1989-08-24

Applicant: MOUNTPELIER INVESTMENTS S.A. ,  FIDDIAN-GREEN, Richard, G.

Inventor： MOUNTPELIER INVESTMENTS S.A.

IPC: A61B05/02

CPC classification number: A61B5/14542 ,  A61B5/14503 ,  A61B5/14539 ,  A61M25/10 ,  A61M25/1011 ,  A61M2025/0177 ,  A61M2025/1061

Abstract: Ischemia in a hollow internal organ can be detected in its incipient stages by obtaining a CO2 sample from within the organ of interest, measuring the partial pressure of CO2 sample, measuring the bicarbonate concentration of an arterial blood sample, and on the basis of these two measurements calculating the pH of the wall of the organ. The value of the pH is an indicator of the onset of ischemia in the organ. The CO2 sample is obtained by a novel catheter (10), multiple embodiments of which are disclosed. Also disclosed is a method for determining the vitality or adequacy of oxygenation of the whole body, or a solid internal organ, by the measurement of the pH of venous blood.

Abstract translation: 通过从感兴趣的器官内获得二氧化碳样本，测量二氧化碳样本的分压，测量动脉血样品的碳酸氢盐浓度，可以在初期阶段检测中空内脏器官缺血，并且基于这两个 测量器官壁的pH值。 pH值是器官缺血发作的指标。 通过新型导管（10）获得二氧化碳样品，其多个实施例被公开。 还公开了通过测量静脉血的pH来确定全身或固体内脏器官的氧合活力或充足性的方法。

公开(公告)号：WO1989010088A1

公开(公告)日：1989-11-02

申请号：PCT/US1989001591

申请日：1989-04-14

Applicant: TARGET THERAPEUTICS

Inventor： TARGET THERAPEUTICS ,  ENGELSON, Erik

IPC: A61B05/02

CPC classification number: A61M25/09 ,  A61M2025/09175

Abstract: A catheter guide wire (20) designed for use in guiding a catheter to a target site along a tortuous vessel path. The guide wire (20) has a relatively long, torqueable proximal wire section (26), a more flexible intermediate section (28), and a most flexible distal end section (30) designed to be advanced across sharp-bend vessel junctions. The intermediate section (28) has greater lubricity than the adjacent proximal and distal sections. The greater frictional coefficient in the distal end segment (30) acts to anchor the end of the wire in a branch vessel, when the guide wire has been advanced across the sharp-bend vessel junction, and the catheter (102) is threaded axially over the wire, while the more lubricious surface (46) of the intermediate section (28) gives reduced sliding friction within the catheter (102) during such advance. The invention also includes a catheter device (100) containing the guide wire and catheter.

公开(公告)号：WO1989008424A1

公开(公告)日：1989-09-21

申请号：PCT/DE1989000152

申请日：1989-03-09

Applicant: VECTRON GESELLSCHAFT FÜR TECHNOLOGIEENTWICKLUNG ... ,  GREUBEL, Waldemar ,  VON MÜLLER, Albrecht, A., C. ,  VON STEIN, Hubertus ,  WIECZOREK, Rudolf

Inventor： VECTRON GESELLSCHAFT FÜR TECHNOLOGIEENTWICKLUNG ...

IPC: A61B05/02

CPC classification number: A61B5/02125 ,  A61B5/02255 ,  A61B5/0285 ,  A61B5/6816 ,  A61B5/7214

Abstract: In a process for continuous measurement of blood pressure, the mean blood pressure is derived from the measured pulse wave duration. The other blood pressure parameters are obtained by combination with an optoelectrical determination of blood volume density in a typical manner at the ear lobes. An initial individual basic calibration of the blood pressure values is carried out by a conventional method. In addition, a continuous automatic optoelectronic post-calibration is carried out. The measuring sensor is preferably an ear clip (10) and ECG electrodes (16) or a photoelectric sensor. The method can be used to particular advantage in prevention and diagnosis.

Abstract translation: 在连续测量血压的过程中，平均血压是根据测得的脉搏波持续时间导出的。 其他血压参数通过与耳瓣的典型方式的血容量密度的光电测定结合获得。 通过常规方法进行血压值的初始个体基本校准。 此外，进行连续的自动光电后校准。 测量传感器优选为耳夹（10）和ECG电极（16）或光电传感器。 该方法可用于预防和诊断中的特别优势。

公开(公告)号：WO1988009642A1

公开(公告)日：1988-12-15

申请号：PCT/FR1988000297

申请日：1988-06-10

Applicant: BERTIN & CIE ,  CHIAFFI, Michel ,  SCHLEGEL, Raymond ,  WEBER, Jean-Luc, Michel ,  CELLIERE, Jean-Claude

Inventor： BERTIN & CIE

IPC: A61B05/02

CPC classification number: A61B5/02208 ,  A61B5/02233 ,  A61B5/0225

Abstract: An ambulatory apparatus for storing data concerning the functioning of the cardiovascular system comprises a casing (3) carried on the inflatable arm-band (1) itself which contains batteries, a miniaturized motocompressor, valves, a microprocessor and RAM memories. The data supplied by a pressure sensor and a microphone (4) are digitized and compressed so that they can be stored in one or more RAM memories whose contents are then transferred to a computer in a health care centre. Advantageously, the disappearance of the KOROTKOV noises at the end of the increase or decrease in pressure controls the beginning and end of memorization.

公开(公告)号：WO1988006425A1

公开(公告)日：1988-09-07

申请号：PCT/BE1988000005

申请日：1988-02-22

Applicant: VAN DEN BERGHE, René

IPC: A61B05/02

CPC classification number: A21B5/02 ,  A23L7/178

Abstract: Apparatus and method for producing shaped products from granular materials, in particular food products from cereals such as rice, corn, wheat or the like, which are pressure-baked and afterwards expanded in a heatable mold defined in a fixed upper mold and a movable lower mold (punch). Preferably the mold comprises a peripheral mold element which is individually movable. Driving means are provided for actuating the movable punch which are in the form of two aligned, separately controlled hydraulic cylinders of which one cylinder defines a precise expansion and the other cylinder controls the compression in combination with separate end switch means.

Abstract translation: 从颗粒状材料，特别是谷物如米，玉米，小麦等的食品中生产成形产品的装置和方法，其被压制烘烤并随后在限定在固定上模和可动下部的可加热模具中膨胀 模具（冲压）。 优选地，模具包括可单独移动的外围模具元件。 提供用于致动可动冲头的驱动装置，其为两个对准的单独控制的液压缸的形式，其中一个气缸限定精确的膨胀，另一个气缸结合独立的端部开关装置来控制压缩。

公开(公告)号：WO1988004910A1

公开(公告)日：1988-07-14

申请号：PCT/JP1987001033

申请日：1987-12-25

Applicant: NIPPON COLIN CO., LTD. ,  UEMURA, Masahiro ,  TSUDA, Hideichi ,  YOKOE, Hifumi

Inventor： NIPPON COLIN CO., LTD.

IPC: A61B05/02

CPC classification number: A61B5/022 ,  A61B5/02116 ,  A61B5/02225

Abstract: In a system of monitoring the blood pressure of a living body for an extended period of time, it is desired to alleviate the pain caused by pressure on the living body. The invention comprises a pulse wave detecting means for detecting pulse waves from the artery of a living body, a blood pressure measuring means for measuring the actual blood pressure of the living body, and a control means which finds a relationship between the pulse waves detected by said pulse wave detecting means and the actual blood pressure measured by the blood pressure measuring means, which determines the blood pressure based on the pulse waves and which continuously displays it on a display unit. From the relationship between the actual blood pressure found by the control means and the pulse waves, therefore, the blood pressure is determined on the basis of the pulse waves and is continuously displayed. Therefore, the blood pressure need not be continuously measured using a cuff, and the pain from which the living body suffers is greatly alleviated.

公开(公告)号：WO1987007128A1

公开(公告)日：1987-12-03

申请号：PCT/US1987001255

申请日：1987-05-29

Applicant: KDL TECHNOLOGIES, INC.

Inventor： KDL TECHNOLOGIES, INC. ,  KRON, Reuben, E. ,  LITT, Mitchell

IPC: A61B05/02

CPC classification number: G01N11/00

Abstract: A clinical whole blood viscometer and a method for obtaining instantaneous whole blood viscosity measurements over a wide range of shear rates with a single blood sample. A conventionally acquired sample of fresh blood (inside 11) is drawn from a patient and directed under pressure in viscous flow so as to deflect a compliant diaphragm (20, 26), then allowing the diaphragm to relax and concurrently measuring the relaxation of said compliant diaphragm continuously so as to determine a profile of viscosity versus shear rate of said sample.

Abstract translation: 一种临床全血粘度计和用单次血液样品在宽范围的剪切速率下获得瞬时全血粘度测量的方法。 常规采集的新鲜血液样本（内部11）从患者抽出并在粘性流动下被压力导向，以使柔顺膜片（20,26）偏转，然后允许隔膜松弛并同时测量所述顺应性 连续地隔膜以便确定所述样品的粘度对剪切速率的曲线。

公开(公告)号：WO1986003956A1

公开(公告)日：1986-07-17

申请号：PCT/SE1986000005

申请日：1986-01-09

Applicant: HÖK, Bertil

IPC: A61B05/02

CPC classification number: G01L9/0077 ,  A61B5/02154 ,  A61B5/02156

Abstract: A device for physiological pressure recordal comprises a miniaturized pressure sensor element (1) which is located near the tip (2) of a guide (3), which in turn is inserted into a catheter (4). The guide (3) and the catheter (4) have sealing surfaces (5, 6; 15, 16) which can be brought into contact with each other by axial or rotary motion of the guide (3) in relation to the catheter (4), whereby the sensor element (1) becomes available for calibration from a pressure generator (7) connected to the catheter (4).

Abstract translation: 用于生理压力记录的装置包括位于引导件（3）的尖端（2）附近的小型化压力传感器元件（1），其又插入导管（4）中。 引导件（3）和导管（4）具有通过引导件（3）相对于导管（4）的轴向或旋转运动而能够彼此接触的密封表面（5,6; 15,16） ），由此传感器元件（1）可用于从连接到导管（4）的压力发生器（7）进行校准。

公开(公告)号：WO1985004087A1

公开(公告)日：1985-09-26

申请号：PCT/GB1985000106

申请日：1985-03-19

Applicant: CARDIAC RECORDERS LIMITED ,  SPENCER, Maria

Inventor： CARDIAC RECORDERS LIMITED

IPC: A61B05/02

CPC classification number: A61B5/0464 ,  A61B5/024 ,  A61B5/04012

Abstract: A cardiac monitor includes a heartbeat rate meter (4), an alarm such as a loudspeaker (11), and a comparator (8) which operates the alarm when the heart rate is abnormal, in particular on cardiac arrest. To enable the staff to know how long the cardiac arrest has lasted, the alarm comparator also triggers a timer (10). The timer can be reset manually, or automatically after normal heart rhythm has been re-established. A delay device (12) is provided so that the timer can be reset only after a delay following resuscitation of the patient. Consequently, if the patient relapses soon after resuscitation the timer will measure the total time spent in cardiac arrest.

公开(公告)号：WO1985003211A1

公开(公告)日：1985-08-01

申请号：PCT/GB1985000030

申请日：1985-01-21

Applicant: JOHNSON MATTHEY PUBLIC LIMITED COMPANY ,  HAWKINS, Peter

Inventor： JOHNSON MATTHEY PUBLIC LIMITED COMPANY

IPC: A61B05/02

CPC classification number: A61B5/02125 ,  A61B5/022 ,  A61B5/0245 ,  A61B5/0285 ,  A61B5/0456

Abstract: A method of and apparatus for determination of blood pressure continuously and non-invasively. The method comprises sensing the heart beat, preferably via ECG, sensing the associated arterial pulse and measuring the time interval between them. Photoplethysmography is conveniently used for sensing the arterial pulse.

Abstract translation: 一种连续不间断地测定血压的方法和装置。 该方法包括感测心搏，优选通过ECG，感测相关的动脉脉搏并测量它们之间的时间间隔。 Photoplethysmography方便地用于感测动脉脉冲。