公开(公告)号：WO1997023161A3

公开(公告)日：1997-07-03

申请号：PCT/IB1996001396

申请日：1996-12-09

Applicant: PHILIPS ELECTRONICS N.V. ,  PHILIPS NORDEN AB

Inventor： PHILIPS ELECTRONICS N.V. ,  PHILIPS NORDEN AB ,  PAPAIOANNOU, Dimitrios ,  'T HOOFT, Gert, Wim

IPC: A61B05/00

公开(公告)号：WO1997022292A1

公开(公告)日：1997-06-26

申请号：PCT/US1996019902

申请日：1996-12-12

Applicant: ABBOTT LABORATORIES

Inventor： ABBOTT LABORATORIES ,  HENNING, Timothy, P. ,  SHAIN, Eric, B. ,  ELSTROM, Tuan, A. ,  WARNKE, Kevin, C.

IPC: A61B05/00

CPC classification number: A61B5/441 ,  A61B5/14514 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/15134 ,  A61B5/157

Abstract: This disclosure relates to a device and method for the non-invasive or minimally invasive withdrawal of fluids from a patient by the use of a self-actuated pump (12) connected to an analyte sensing unit (16). The self-actuated pump (12) is preferably mounted in the patient's shoe (38).

Abstract translation: 本公开涉及一种用于通过使用连接到分析物感测单元（16）的自动泵（12）从患者非侵入性或最小程度地取出流体的装置和方法。 自动泵（12）优选安装在患者鞋（38）中。

公开(公告)号：WO1997018749A1

公开(公告)日：1997-05-29

申请号：PCT/US1996018607

申请日：1996-11-20

Applicant: UTAH MEDICAL PRODUCTS, INC. ,  BILLINGS, R., Gail ,  SMITH, Roger, E.

Inventor： UTAH MEDICAL PRODUCTS, INC.

IPC: A61B05/00

CPC classification number: A61B5/0084 ,  A61B5/035

Abstract: A system for intrauterine detection of one or more biological substances, such as meconium or blood, is disclosed. The presence in amniotic fluid of such biological substances indicates an abnormal condition which justifies intervention on the part of a medical practitioner supervising the labor and delivery. A flexible cable (14) which can be inserted into the uterus is provided which includes at least two lumens. The first lumen is used to draw amniotic fluid through a port (16) in the lumen and into an observation chamber outside of the uterus and at the end of the first lumen. The fluid is visually observed by a medical practitioner for the presence of a biological substance or the biological substance can be detected by any one of several described instruments. It is preferred that if an instrument is used to detect the biological substance that a transparent visual observation chamber also be included to allow visual detection also. The apparatus allows stained fluid to be withdrawn from, and clean fluid to be infused into, the uterus in order to reduce the concentration of, and the effect of, the undesirable biological substance in the uterus.

Abstract translation: 公开了一种用于子宫内检测一种或多种生物物质如胎粪或血液的系统。 这种生物物质在羊水中的存在表明这是一种异常情况，证明医务人员监督劳动和分娩方面的干预。 提供了可以插入到子宫中的柔性电缆（14），其包括至少两个流明。 第一个管腔用于通过内腔中的一个端口（16）吸收羊水，并进入到子宫外部和第一个管腔末端的观察室。 医疗人员目视观察流体是否存在生物物质，或者可以通过几种所述仪器中的任何一种来检测生物物质。 优选的是，如果使用仪器来检测生物物质，也可以包括透明目视观察室以允许视觉检测。 该装置允许将染色的流体从子宫中取出并清洗以输入到子宫中，以减少子宫中不良生物物质的浓度和影响。

公开(公告)号：WO1997017889A1

公开(公告)日：1997-05-22

申请号：PCT/US1996017598

申请日：1996-11-04

Applicant: APPLIED MEDICAL RESOURCES CORPORATION

Inventor： APPLIED MEDICAL RESOURCES CORPORATION ,  HART, Charles, C.

IPC: A61B05/00

CPC classification number: A61M25/10 ,  A61B17/22031 ,  A61B17/22032 ,  A61B17/320725 ,  A61B2017/22034 ,  A61M25/1002 ,  A61M25/1011 ,  A61M29/02 ,  A61M2025/1068 ,  A61M2025/1072 ,  A61M2025/109

Abstract: The expandable intraluminal catheter (10) is used for removing occlusive material from a body passage. The catheter includes a handle (12) having both a proximal handle end and a distal handle end. Attached to the distal handle end is an elongate tubular body (16) which includes a proximal elongate tubular body end and a distal elongate tubular body end (15). The elongate tubular body further includes a lumen (46) between the proximal elongate tubular body end and the distal elongate tubular body end. A number of radially expandable segments (17) are disposed on the elongate tubular body near the distal elongate tubular body end. These radially expandable segments can be mechanically activated by a user when the distal elongate tubular body end is within a blood vessel, to thereby contact and partition occlusive material within the blood vessel. The partitioned occlusive material within the blood vessel can then be removed.

Abstract translation: 可扩张的管腔内导管（10）用于从身体通道中去除闭塞性材料。 导管包括具有近端手柄端和远端手柄端的手柄（12）。 附接到远侧手柄端部的是细长的管状体（16），其包括近端细长管状体端部和远端细长管状体端部（15）。 细长管状体还包括在近端细长管状本体端和远端细长管状本体端之间的内腔（46）。 多个可径向扩张的区段（17）设置在远端细长管状体端部附近的细长管状体上。 当远端细长管状体端部位于血管内时，这些可径向扩张的区段可由使用者机械地启动，从而接触和分隔血管内的闭塞性材料。 然后可以移除血管内的分隔闭塞材料。

公开(公告)号：WO1997012544A1

公开(公告)日：1997-04-10

申请号：PCT/US1996016001

申请日：1996-10-04

Applicant: TEVITAL, INC.

Inventor： TEVITAL, INC. ,  BELLER, Alexander, S. ,  COLOMBO, Joseph ,  HRIBAR, Adrien, J. ,  WARNER, Ilene, K. ,  FABIAN, Frank ,  MOCENTER, Michael, E.

IPC: A61B05/00

CPC classification number: G06F19/3456 ,  G06F19/00 ,  G06F19/3418 ,  H04N7/147 ,  H04N7/15 ,  H04N2007/145 ,  Y10S128/904

Abstract: A teleconference system uses video conference between a nurse station (76) and a patient station (68) to deliver medical care. The patient station (68) is programmed to contain customized instructions concerning medications, procedures, or visitations that were placed there by the nurse. The customized audio, video, and text information transforms the patient station (68) into a highly personalized information source which can be reviewed by the patient when the unit is off line. Medical procedures and medications are also programmed into the patient station by the nurse to remind the patient of all scheduled events, including visitations. A record of medical compliance is stored in the patient station, which record is uploaded to the nurse station (76) and compared to the original event schedule. In such manner, the patient station (68) is an intelligent personal medical assistant, programmed by the nurse to provide customized reminders and information necessary for the efficient management of the patient's illness.

Abstract translation: 电话会议系统使用护士站（76）和病人站（68）之间的视频会议来提供医疗保健。 患者站（68）被编程为包含关于护士放置在那里的药物，程序或访问的定制说明。 定制的音频，视频和文本信息将患者站（68）变换成高度个性化的信息源，当单元离线时可以由患者来查看。 医疗程序和药物也由护士编入患者站，以提醒患者所有预定的事件，包括访问。 医疗合规记录存储在患者站中，该记录被上传到护士站（76）并与原始事件进度进行比较。 以这种方式，患者站（68）是智能个人医疗助理，由护士编程以提供定制的提示和有效管理患者疾病所需的信息。

公开(公告)号：WO1997006725A1

公开(公告)日：1997-02-27

申请号：PCT/US1996013264

申请日：1996-08-16

Applicant: DUKE UNIVERSITY

Inventor： DUKE UNIVERSITY ,  OHMAN, E., Magnus ,  CHRISTENSON, Robert, H. ,  CALIFF, Robert, M. ,  O'HANESIAN, Mary, Ann ,  SIGMON, Kristina, N.

IPC: A61B05/00

CPC classification number: C12Q1/50 ,  G01N33/6887 ,  G06F19/00 ,  G16H15/00

Abstract: The present invention is a method of diagnosing the presence of a persistent occlusion in a myocardial infarct patient undergoing thrombolytic therapy. The method comprises detecting a series of five variables from the patient and then generating the probability of the presence of a persistent occlusion from those variables. The first variable comprises a serum creatine kinase MB (CK-MB) level (10) from a patient at the onset of thrombolytic therapy. The second variable comprises a second CK-MB level (20) in the patient at a predetermined time after the onset of thrombolytic therapy. The third variable comprises the presence or absence of chest pain (50) a predetermined time after the onset of thrombolytic therapy. The fourth variable comprises the serum myoglobin level (30) in the patient at a predetermined time after the onset of thrombolytic therapy. In a preferred embodiment of the present invention, the second, third and fourth variables are detected within 30 minutes of each other and within about 1 hour to 3 hours after the initial variable is detected. In an alternate embodiment a fifth variable reflecting the time from onset of chest pain to the beginning of thrombolytic therapy is included in the regression model.

Abstract translation: 本发明是诊断经历溶栓治疗的心肌梗死患者中持续性闭塞的存在的方法。 该方法包括从患者中检测一系列五个变量，然后从这些变量产生持续闭塞的存在概率。 第一个变量包括来自溶栓治疗开始时患者的血清肌酸激酶MB（CK-MB）水平（10）。 第二变量在溶栓治疗开始后的预定时间包括患者的第二CK-MB水平（20）。 第三个变量包括在溶栓治疗开始后的预定时间内存在或不存在胸痛（50）。 第四个变量包括在溶栓治疗开始后的预定时间内患者的血清肌红蛋白水平（30）。 在本发明的优选实施例中，第二，第三和第四变量在彼此之间的30分钟内检测到，并且在检测到初始变量之后的大约1小时至3小时之内。 在替代实施例中，回归模型中包括反映从胸痛发作到溶栓治疗开始的时间的第五变量。

公开(公告)号：WO1997005819A1

公开(公告)日：1997-02-20

申请号：PCT/US1996012486

申请日：1996-07-30

Applicant: RIO GRANDE MEDICAL TECHNOLOGIES, INC.

Inventor： RIO GRANDE MEDICAL TECHNOLOGIES, INC. ,  MESSERSCHMIDT, Robert, G.

IPC: A61B05/00

CPC classification number: A61B5/1455 ,  A61B5/14532 ,  A61B5/1495 ,  A61B2562/146 ,  Y10S514/937

Abstract: This invention is a method for non-invasive measuring of the concentration of an analyte, particularly blood analyte in blood. The method utilizes spectrographic techniques in conjunction with an improved optical interface between a sensor probe (11) and a skin surface (12) or tissue surface of the body containing the blood to be analyzed. An index matching medium (22) is disclosed to improve the interface between the sensor probe (11) and the skin surface (12) during spectrographic analysis. In a preferred embodiment, the blood analyte concentration in blood is quantified utilizing a partial square analysis relative to a model incorporating analysis of plural known blood samples.

Abstract translation: 本发明是用于非侵入性测量血液中分析物，特别是血液分析物浓度的方法。 该方法利用光谱技术结合传感器探针（11）和皮肤表面（12）之间的改进的光学界面或包含待分析血液的身体的组织表面。 公开了一种索引匹配介质（22），以在光谱分析期间改进传感器探针（11）和皮肤表面（12）之间的界面。 在一个优选实施方案中，使用相对于包含多个已知血液样品分析的模型的部分平方分析来定量血液中的血液分析物浓度。

公开(公告)号：WO1997000041A1

公开(公告)日：1997-01-03

申请号：PCT/US1996010296

申请日：1996-06-12

Applicant: NELLCOR PURITAN BENNETT INCORPORATED

Inventor： NELLCOR PURITAN BENNETT INCORPORATED ,  YORKEY, Thomas, J.

IPC: A61B05/00

CPC classification number: A61B5/14551 ,  A61B5/7207 ,  A61B5/7239

Abstract: Motion compensation is based on analysis of intensity signals received by detectors, without separately measuring a motion signal, without providing feedback to cancel the motion signal and without attempting to mathematically eliminate the motion signal. Instead, the present invention mathematically recognizes the presence of the motion signal and recognizes a few key characteristics of the motion signal and makes corresponding assumptions. First, it is recognized that the motion/noise in each wavelength signal is proportional. Second, it is assumed that the blood pulse signal is not affected by motion.

Abstract translation: 运动补偿基于对检测器接收的强度信号的分析，而不需要单独测量运动信号，而不提供反馈以消除运动信号，而不尝试以数学方式消除运动信号。 相反，本发明在数学上识别运动信号的存在并识别运动信号的几个关键特征并作出相应的假设。 首先，认识到每个波长信号中的运动/噪声是成比例的。 其次，假设脉搏信号不受运动影响。

公开(公告)号：WO1996039073A1

公开(公告)日：1996-12-12

申请号：PCT/US1996010116

申请日：1996-06-06

Applicant: CAMPBELL SOUP COMPANY ,  CHAIT, Alan ,  HATTON, Dan ,  HAYNES, R., Brian ,  KHOO, Chor, San, Heng ,  KRIS-ETHERTON, Penny ,  MACNAIR, R., David, C. ,  MCCARRON, David ,  METZ, Jill ,  OPARIL, Suzanne ,  PI-SUNYER, Xavier ,  RESNICK, Larry ,  STERN, Judith, S. ,  ZIEGLER, Paula, J.

Inventor： CAMPBELL SOUP COMPANY

IPC: A61B05/00

CPC classification number: A61B5/14507 ,  A23L33/30 ,  A61B5/00 ,  A61B5/20

Abstract: The invention is a method for determining the effectiveness of a diet program for administration to a patient having at least one diet-responsive condition. The method includes the steps of selecting a plurality of patients, each having at least one diet-responsive condition; identifiying at least one quantifiable indicator of each of the diet-responsive conditions and measuring the at least one indicator for each of the patients during a four week baseline period; and monitoring each of the patients during the baseline period to determine a baseline quality of life. The plurality of patients is divided randomly between a first group and a second group. The diet program is administered to each of the patients in the first group during a ten week intervention period and each of the patients in the second group is maintained on a control diet with known beneficial effects on the at least one diet-responsive condition during the intervention period. The at least one indicator of each of the conditions is monitored for each of the patients after the intervention period.

Abstract translation: 本发明是一种用于确定用于给予具有至少一种饮食反应状况的患者的饮食程序的有效性的方法。 该方法包括以下步骤：选择多个患者，每个患者具有至少一种饮食反应状态; 识别每个饮食反应性条件的至少一个可量化指标，并在四周的基准期内测量每个患者的至少一个指标; 并在基线期间监测每个患者以确定基线生活质量。 多个患者在第一组和第二组之间随机分配。 在10周的干预期间，对第一组的每个患者进行饮食计划，并且将第二组中的每个患者维持在具有已知的有益作用的对照饮食中，以在至少一种饮食反应状态期间 干预期 在干预期后，对每个患者监测每个病症的至少一个指标。

公开(公告)号：WO1996038080A2

公开(公告)日：1996-12-05

申请号：PCT/FR1996000832

申请日：1996-06-03

Applicant: BITTON, Paul, Elie ,  UZAN, David, Claude

IPC: A61B05/00

CPC classification number: A61B5/0002 ,  A61B5/02455

Abstract: The system provides for the remote and permanent monitoring by radiofrequency with alarm of an infant, a child or an adult. A miniature sensor-emitter, attached to the wrist of the patient, comprises a sensor (1) which detects the beats of the pulse, a circuit (2) intended to shape and code the information concerning the "rate of heart beat" and "presence of cardiac pauses", if any, and an emitter (3) sends the radiofrequency signal S. A receiver-display unit provides for the remote monitoring of the patient and comprises a radiofrequency receiver (7) intended to pick up the signal S, a circuit (8) providing for the decoding of the signal S, and the display of the rate of heart beat R by means of a digital display (9). The circuit (8) further compares permanently R with minimum and maximum values, and sets off alarms (10, 11 and 21) if said extreme values are exceeded, or if cardiac pauses are detected.

Abstract translation: 该系统通过射频与婴儿，儿童或成年人的闹钟进行远程和永久性监测。 附着在患者手腕上的微型传感器 - 发射器包括检测脉搏节拍的传感器（1），用于形成和编码关于“心率”的信息的电路（2）和“ 心脏停顿的存在“，发射器（3）发射射频信号S.接收器显示单元提供对患者的远程监视，并且包括用于接收信号S的射频接收器（7） 提供信号S的解码的电路（8），以及通过数字显示器（9）显示心率R的速率。 电路（8）还进一步将R与最小值和最大值进行比较，并且如果超过了所述极值，则停止警报（10,11和21），或者如果检测到心跳停顿。