公开(公告)号：US20150276599A1

公开(公告)日：2015-10-01

申请号：US14437964

申请日：2013-10-23

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Takuji Kataoka ,  Taira Ito ,  Natsumi Saito

IPC: G01N21/64 ,  G01N33/483

CPC classification number: G01N21/6428 ,  G01N33/4836 ,  G01N33/48728 ,  G01N33/5005 ,  G01N2201/022

Abstract: A cell observation system 1 is a cell observation system 1 for observing a cell held by a microplate 20 having a plurality of wells 21 arranged therein for holding a sample S including the cell and comprises a microplate holder 11 for mounting the microplate 20, an electrical stimulator 16 arranged with a plurality of electrode pairs 17 including positive and negative electrodes 17b, 17a, and a data analyzer 50 for controlling a position of the electrical stimulator 16 so as to place the electrode pairs 17 within the wells 21 of the microplate 20, while a leading end of the negative electrode 17a on the well 21 side extends longer than a leading end of the positive electrode 17b on the well 21 side.

Abstract translation: 细胞观察系统1是细胞观察系统1，用于观察由微孔板20保持的细胞，该微孔板20具有布置在其中的多个孔21，用于保持包括细胞的样品S，并且包括用于安装微板20的微孔板保持器11， 激励器16，其配置有包括正极和负极17b，17a的多个电极对17，以及用于控制电刺激器16的位置以将电极对17放置在微板20的孔21内的数据分析器50， 而在井21侧的负极17a的前端比阱21侧的正极17b的前端延伸。

公开(公告)号：US20150268163A1

公开(公告)日：2015-09-24

申请号：US14439046

申请日：2013-10-28

Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES ,  BIOMERIEUX

Inventor： Mathieu Dupoy ,  Mathieu Debourdeau ,  Frédéric Pinston

IPC: G01N21/47 ,  C12Q1/02

CPC classification number: G01N21/47 ,  C12M23/10 ,  C12M41/36 ,  C12Q1/02 ,  G01N21/4738 ,  G01N2201/022 ,  G01N2201/06113 ,  G01N2201/0633

Abstract: A method for observing biological species on a culture medium contained in a container having at least one translucent face, the method including the steps of: a) directing a light beam onto one portion of the translucent face, so as to define at least one illuminated region and at least one non-illuminated region of the face; and b) acquiring an image of a portion of the surface of the culture medium illuminated by the light beam, the acquisition being carried out through at least one of the non-illuminated regions of the translucent face and along an optical acquisition axis forming a non-zero angle (a) with the direction of propagation of the light beam.

Abstract translation: 一种用于观察包含在具有至少一个半透明面的容器中的培养基上的生物物种的方法，所述方法包括以下步骤：a）将光束引导到半透明面的一部分上，以限定至少一个照明 区域和面部的至少一个非照明区域; 以及b）获取由所述光束照射的所述培养基的表面的一部分的图像，所述获取通过所述半透明面的所述非照明区域中的至少一个并且沿着形成非光照的光学获取轴进行， （a）与光束的传播方向。

公开(公告)号：US20150226665A1

公开(公告)日：2015-08-13

申请号：US14422924

申请日：2013-08-09

Applicant: THE SCIENCE AND TECHNOLOGY FACILITIES COUNCIL

Inventor： Damien Weidmann ,  Richard Brownsword

IPC: G01N21/39 ,  G01N21/3504

CPC classification number: G01N21/39 ,  G01J3/42 ,  G01J2003/423 ,  G01N21/3504 ,  G01N2021/396 ,  G01N2201/022 ,  G01N2201/06113

Abstract: Method and apparatus for external cavity laser absorption spectroscopy There is disclosed an apparatus, and corresponding methods, for determining one or more characteristics of a sample in an absorption cell using laser absorption spectroscopy. For example, the characteristic may be concentration of a species in the sample. The apparatus comprises an external cavity semiconductor laser comprising a semiconductor gain medium within an optical resonator. The absorption cell is located within the optical resonator of the external cavity semiconductor laser so as to be optically coupled with the gain medium. A controller is arranged to provide a varied injection current to the semiconductor gain medium. A photodetector is arranged to detect laser light output by the external cavity semiconductor laser. An analyser is arranged to determine one or more characteristics of the sample from behaviour of the detected laser light output as a function of the varied injection current.

Abstract translation: 用于外腔激光吸收光谱的方法和装置公开了一种用于使用激光吸收光谱确定吸收单元中的样品的一个或多个特性的装置和相应的方法。 例如，特征可以是样品中物种的浓度。 该装置包括在光谐振器内包括半导体增益介质的外腔半导体激光器。 吸收单元位于外腔半导体激光器的光学谐振器内，以便与增益介质光耦合。 控制器被布置成向半导体增益介质提供变化的注入电流。 光检测器被布置成检测由外腔半导体激光器输出的激光。 分析器被布置成根据检测到的激光输出的行为来确定样品的一个或多个特性作为改变的注入电流的函数。

公开(公告)号：US08994947B2

公开(公告)日：2015-03-31

申请号：US13752320

申请日：2013-01-28

Applicant: Pranalytica, Inc.

Inventor： C. Kumar Patel ,  L. Ravi Narasimhan

IPC: G01N21/59 ,  G01N21/39

CPC classification number: G01N21/39 ,  G01N21/1702 ,  G01N21/59 ,  G01N2021/1704 ,  G01N2201/022 ,  G01N2201/06113

Abstract: A method for detecting component concentrations in human gas emissions such as breath and gas emitted from skin. A gas sample containing a specified component is collected into a gas cell using a pump and a series of valves to draw the gas sample into the cell and control the gas pressure within the cell. A tunable optical radiation beam is passed through the gas cell and the amount of energy absorbed by the specified component may be measured indirectly by taking the difference between the incident and emerging beam energy or directly by optoacoustic methods. Concentrations of the specified component as small as 0.1 ppB may be determined. Additionally, the tunable optical radiation beam may be multiplexed for use with a plurality of systems utilizing the beam for medical purposes.

Abstract translation: 一种检测人体气体排放物中成分浓度的方法，如从皮肤发出的呼吸和气体。 使用泵和一系列阀将含有特定组分的气体样品收集到气室中，以将气体样品吸入电池并控制电池内的气体压力。 可调谐的光辐射束通过气室，并且可以通过考虑入射光束能量和出射光束能量之间的差异或直接通过光声法间接地测量由特定部件吸收的能量的量。 可以确定小于0.1ppB的指定组分的浓度。 此外，可调谐光辐射束可以被复用以与利用用于医疗目的的光束的多个系统一起使用。

公开(公告)号：US20140211208A1

公开(公告)日：2014-07-31

申请号：US13752320

申请日：2013-01-28

Applicant: C. Kumar N. Patel ,  L. Ravi Narasimhan

Inventor： C. Kumar N. Patel ,  L. Ravi Narasimhan

IPC: G01N21/59

CPC classification number: G01N21/39 ,  G01N21/1702 ,  G01N21/59 ,  G01N2021/1704 ,  G01N2201/022 ,  G01N2201/06113

Abstract: A method for detecting component concentrations in human gas emissions such as breath and gas emitted from skin. A gas sample containing a specified component is collected into a gas cell using a pump and a series of valves to draw the gas sample into the cell and control the gas pressure within the cell. A tunable optical radiation beam is passed through the gas cell and the amount of energy absorbed by the specified component may be measured indirectly by taking the difference between the incident and emerging beam energy or directly by optoacoustic methods. Concentrations of the specified component as small as 0.1 ppB may be determined. Additionally, the tunable optical radiation beam may be multiplexed for use with a plurality of systems utilizing the beam for medical purposes.

Abstract translation: 一种检测人体气体排放物中成分浓度的方法，如从皮肤发出的呼吸和气体。 使用泵和一系列阀将含有特定组分的气体样品收集到气室中，以将气体样品吸入电池并控制电池内的气体压力。 可调谐的光辐射束通过气室，并且可以通过考虑入射光束能量和出射光束能量之间的差异或直接通过光声法间接地测量由特定部件吸收的能量的量。 可以确定小于0.1ppB的指定组分的浓度。 此外，可调谐光辐射束可以被复用以与利用用于医疗目的的光束的多个系统一起使用。

公开(公告)号：US20140168647A1

公开(公告)日：2014-06-19

申请号：US13717849

申请日：2012-12-18

Applicant: EXCELITAS CANADA, INC.

Inventor： Jin Han Ju ,  Arthur John Barlow

IPC: G01N21/47

CPC classification number: G01N21/53 ,  G01N2201/022 ,  G08B17/107 ,  G08B17/113 ,  H05K3/325 ,  Y10T29/49002 ,  Y10T29/49826 ,  Y10T29/4998

Abstract: A device and method for manufacturing an integrated smoke cell are presented. The smoke cell includes an integral housing with a ceiling portion and a smoke permeable wall forming a chamber when mounted on a printed circuit board. An emitter and detector are mounted above apertures in the chamber ceiling so the emitter and detector are mounted substantially outside the chamber while detecting smoke present within the chamber without blocking ingress of smoke through the chamber wall.

Abstract translation: 提出了一种用于制造集成烟雾池的装置和方法。 烟室包括具有天花板部分的一体式外壳和安装在印刷电路板上时形成室的透烟壁。 发射器和检测器安装在腔室顶部的孔上方，因此发射器和检测器基本上安装在腔室外部，同时检测室内存在的烟雾，而不会阻止烟雾通过腔室壁进入。

公开(公告)号：US20120290208A1

公开(公告)日：2012-11-15

申请号：US13104388

申请日：2011-05-10

Applicant: Li Jiang ,  Terizhandur S. Ramakrishnan ,  Timothy G.J. Jones ,  Roy Koveleski ,  Albert Perez, JR.

Inventor： Li Jiang ,  Terizhandur S. Ramakrishnan ,  Timothy G.J. Jones ,  Roy Koveleski ,  Albert Perez, JR.

IPC: G01V5/04 ,  G01J5/02 ,  G06F19/00

CPC classification number: G01N21/552 ,  G01N21/3504 ,  G01N2201/0218 ,  G01N2201/022

Abstract: A sensing apparatus (and corresponding method) for monitoring carbon dioxide dissolved in a liquid solution employs a crystal surrounded in part by a sample chamber such that, in use, the liquid solution is in direct contact with the crystal.

Abstract translation: 用于监测溶解在液体溶液中的二氧化碳的感测装置（和相应的方法）采用部分由样品室包围的晶体，使得在使用中，液体溶液与晶体直接接触。

公开(公告)号：US08223325B2

公开(公告)日：2012-07-17

申请号：US12563396

申请日：2009-09-21

Applicant: Arthur E Colvin, Jr. ,  Casey J. O'Connor ,  Daniel C. Ferraro

Inventor： Arthur E Colvin, Jr. ,  Casey J. O'Connor ,  Daniel C. Ferraro

IPC: G01J3/00

CPC classification number: G01J3/02 ,  G01J3/0256 ,  G01J3/0264 ,  G01J3/0272 ,  G01J3/4406 ,  G01N21/55 ,  G01N21/6428 ,  G01N21/645 ,  G01N21/77 ,  G01N2021/6421 ,  G01N2021/6441 ,  G01N2021/7786 ,  G01N2201/022 ,  G01N2201/062

Abstract: The present invention provides systems and methods for measuring an analyte in a medium without exposing the medium to contamination. The systems and methods employ a novel combination of a small sensor device embedded in a Luer cap and capable of wirelessly transmitting data to a reading device.

Abstract translation: 本发明提供用于测量介质中的分析物而不将介质暴露于污染物的系统和方法。 该系统和方法采用嵌入鲁尔盖中的小型传感器装置的新颖组合，并能够将数据无线传输到读取装置。

公开(公告)号：US08154728B2

公开(公告)日：2012-04-10

申请号：US12347368

申请日：2008-12-31

Applicant: Xuejiao Hu ,  Alfred Feitisch

Inventor： Xuejiao Hu ,  Alfred Feitisch

IPC: G01N21/00 ,  H01S3/04

CPC classification number: G01N21/39 ,  G01N2201/022 ,  G01N2201/023 ,  G01N2201/0231

Abstract: Thermally controlled enclosures that can be used with gas analyzers are described. The enclosures incorporate one or more phase changing materials that buffer ambient and internal heat loads to reduce the power consumption demand of mechanical or electronic heating apparatus. Maintenance of gas analyzer equipment at a consistent temperature can be important to achieving stable and reproducible results. Related systems, apparatus, methods, and/or articles are also described.

Abstract translation: 描述了可用于气体分析仪的热控制外壳。 外壳采用缓冲环境和内部热负荷的一种或多种相变材料，以减少机械或电子加热设备的功耗需求。 在一致的温度下维护气体分析仪设备对于获得稳定和可重现的结果是重要的。 还描述了相关系统，装置，方法和/或制品。

公开(公告)号：US08119067B2

公开(公告)日：2012-02-21

申请号：US12651773

申请日：2010-01-04

Applicant: Tsung-Kai Chuang ,  Chien-Ho Chuang ,  Jiann-Hua Wang

Inventor： Tsung-Kai Chuang ,  Chien-Ho Chuang ,  Jiann-Hua Wang

IPC: G01N21/00

CPC classification number: G01N21/01 ,  G01N21/8483 ,  G01N2201/022

Abstract: An automatic physiological assay device analyzes light reflected by an assay device and prevents ambient light from interfering with the assay device. The automatic physiological assay device in accordance with the present invention comprises a chassis, an assay device connector assembly, an assay device and a light detecting device. The chassis comprises closed bottom, multiple sidewalls, an inner cavity, an open top and a removable top cover. The assay device connector assembly is mounted slidably through a sidewall and comprises an outer end, two sides and a cover. The cover is mounted on the outer end, seals the sidewall and keeps ambient light away from the assay device. The light detecting device is mounted in the inner cavity and on top edges of guides adjacent the assay device connector assembly.

Abstract translation: 自动生理测定装置分析由测定装置反射的光，并防止环境光干扰测定装置。 根据本发明的自动生理测定装置包括底盘，测定装置连接器组件，测定装置和光检测装置。 底盘包括封闭的底部，多个侧壁，内腔，敞开的顶部和可移除的顶盖。 测定装置连接器组件可滑动地安装在侧壁上并且包括外端，两侧和盖。 盖子安装在外端，密封侧壁并保持环境光远离测定装置。 光检测装置安装在内腔中并且在与测定装置连接器组件相邻的引导件的顶部边缘上。