公开(公告)号：US20110168915A1

公开(公告)日：2011-07-14

申请号：US13119418

申请日：2008-09-18

Applicant: Atsushi Yajima ,  Ichiro Oda ,  Kentaro Hizume ,  Yoshio Tsunazawa

Inventor： Atsushi Yajima ,  Ichiro Oda ,  Kentaro Hizume ,  Yoshio Tsunazawa

IPC: G01N21/64

CPC classification number: G01N21/6458 ,  A61B5/0059 ,  G01J3/4406 ,  G01J2003/1226 ,  G01N21/6428 ,  G01N2021/6471 ,  G01N2201/0612 ,  G01N2201/064 ,  G02B5/285 ,  G02B21/0032 ,  G02B21/0076

Abstract: In order to reduce light leak influencing the detection capability of a fluorescence imaging apparatus, an interference filter and an absorption filter on an emission-side filter section are arranged serially in the traveling direction of the fluorescence. The interference filter and the absorption filter that are in use for such an arrangement block the waveband light equivalent to the excitation light irradiated onto a sample while fully transmitting the waveband light equivalent to the fluorescence.

Abstract translation: 为了减少影响荧光成像装置的检测能力的光泄漏，发射侧滤波器部分上的干涉滤光器和吸收滤光器在荧光的行进方向上串联布置。 用于这种布置的干涉滤光器和吸收滤光器在完全透射等效于荧光的波段光的同时，阻挡与照射到样品上的激发光相当的波段光。

公开(公告)号：US20090279093A1

公开(公告)日：2009-11-12

申请号：US12304288

申请日：2007-05-15

Applicant: Maarten Marinus Johannes Wilhelmus Van Herpen ,  Derk Jan Wilfred Klunder ,  Marcello Leonardo Mario Balistreri ,  Mark Thomas Johnson ,  Marc Wilhelmus Gijsbert Ponjee

Inventor： Maarten Marinus Johannes Wilhelmus Van Herpen ,  Derk Jan Wilfred Klunder ,  Marcello Leonardo Mario Balistreri ,  Mark Thomas Johnson ,  Marc Wilhelmus Gijsbert Ponjee

IPC: G01N21/25 ,  G01N21/64 ,  B23P11/00

CPC classification number: G01N21/6454 ,  B01J2219/00576 ,  B01J2219/00702 ,  B01L3/502707 ,  B01L3/502715 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/0819 ,  B01L2300/1827 ,  G01N21/6428 ,  G01N21/648 ,  G01N2021/0307 ,  G01N2021/7786 ,  G01N2201/0221 ,  G01N2201/0636 ,  G01N2201/064 ,  Y10T29/49826

Abstract: An integrated biosensing device detects emissions from a sample when illuminated. A photo detector (20) is adjacent a site for retaining the sample (40) or receiving excitation radiation for impingement on the sample (40). A reflector (10) deflects the illumination onto the sample site and substantially guides the excitation radiation away from the photo detector. By providing a reflector, a ratio of desired detection of emissions to unwanted detection of the illumination light can be improved. This can be achieved by a reduction in an amount of the illumination reaching the photo detector, and/or by an increase in the amount of illumination of the sample and thus in the amount of emissions reaching the detector. This can be achieved more cost effectively than by using a filter. The illumination can be from above or below if the substrate is transparent.

Abstract translation: 集成的生物传感装置在照明时检测样品的发射。 光检测器（20）邻近用于保持样品（40）的位置或接收用于冲击在样品（40）上的激发辐射。 反射器（10）将照明偏转到样品位置并且基本上将激发辐射引导离开光电检测器。 通过提供反射器，可以提高发射的期望检测与照明光的不期望的检测的比率。 这可以通过减少到达光电检测器的照射量的减少和/或通过增加样品的照射量以及因此到达检测器的排放量来实现。 这可以比通过使用过滤器更经济地实现。 如果基板是透明的，照明可以从上方或下方。

公开(公告)号：US20090179159A1

公开(公告)日：2009-07-16

申请号：US12319924

申请日：2009-01-14

Applicant: Masayuki Yamada

Inventor： Masayuki Yamada

IPC: G01N21/64 ,  G01J1/58

CPC classification number: G01N21/474 ,  G01N21/01 ,  G01N21/6456 ,  G01N2021/6484 ,  G01N2201/064

Abstract: A fluorescence detecting apparatus includes: an excitation light emitter for emitting excitation light exciting a fluorescent material onto a measurement object; an illumination light emitter for emitting illumination light onto the measurement object; an image pickup device for sensing light from the measurement object; and a controller for controlling the image pickup device, the excitation light emitter, and the illumination light emitter. The excitation light is emitted from the excitation light emitter onto the measurement object to define an image pickup condition of the image pickup device, based on an image pickup result to be obtained by sensing light from the measurement object by the image pickup device. A light amount of the illumination light to be emitted from the illumination light emitter is set depending on the image pickup condition. The excitation light, and the illumination light of the set light amount are simultaneously emitted from the excitation light emitter and the illumination light emitter, to cause the image pickup device to sense light from the measurement object.

Abstract translation: 荧光检测装置包括：激发光发射器，用于将激发荧光材料的激发光发射到测量对象上; 照明光发射器，用于将照明光发射到所述测量对象上; 用于感测来自测量对象的光的图像拾取装置; 以及用于控制图像拾取装置，激发光发射器和照明光发射器的控制器。 基于通过由图像拾取装置感测来自测量对象的光而获得的图像拾取结果，激发光从激发光发射器发射到测量对象上以限定图像拾取装置的图像拾取条件。 根据摄像条件设定从照明光发射器发射的照明光的光量。 激发光和设定光量的照明光同时从激发光发射器和照明光发射器发射，以使摄像装置感测来自测量对象的光。

公开(公告)号：US20090009758A1

公开(公告)日：2009-01-08

申请号：US12043434

申请日：2008-03-06

Applicant: Anthony C. Gilby

Inventor： Anthony C. Gilby

IPC: G01N21/01

CPC classification number: G01N21/552 ,  G01N21/0303 ,  G01N21/05 ,  G01N30/74 ,  G01N2021/0346 ,  G01N2021/052 ,  G01N2201/064

Abstract: The present invention is directed to the use of a light absorbing wall material to eliminate stray light paths in light-guiding structures, such as those used for HPLC absorbance detection. More specifically, the present invention relates to the use of carbon-doped Teflon® AF, or “black Teflon® AF,” for all or part of the walls of a light-guiding flowcell adapted for use in HPLC absorbance detection.

Abstract translation: 本发明涉及使用光吸收壁材料来消除导光结构中的杂散光路径，例如用于HPLC吸光度检测的那些。 更具体地，本发明涉及适用于HPLC吸光度检测的导光流动池的全部或部分壁的碳掺杂特氟隆AF或“黑色特氟隆AF”的用途 。

公开(公告)号：US07405827B2

公开(公告)日：2008-07-29

申请号：US11661914

申请日：2005-09-08

Applicant: Reino Keränen

Inventor： Reino Keränen

IPC: G01N21/00

CPC classification number: G01N21/3504 ,  G01N21/09 ,  G01N2021/0396 ,  G01N2201/0636 ,  G01N2201/0638 ,  G01N2201/064

Abstract: This publication discloses an apparatus and method for measuring a gas content. The apparatus includes a light transmitter (1), by means of which coherent light can be sent to the measurement object (3), a receiver (2), by means of which light that has passed through the measurement object (3) can be detected, and optical means (4, 5, 6), by means of which the light intensity of the light transmitter (1) can be aimed at the receiver (2). According to the invention, the optical means include a lens element (4), the optical axis of which is arranged essentially obliquely relative to the longitudinal axis of the measurement object (3), so that the angles of the normals of the optical boundaries relative to the measuring signal are set obliquely. The lens element (4) is both a refracting and a reflecting element, and separates the measurement object (3) from the means (1, 2, 5).

Abstract translation: 该出版物公开了一种用于测量气体含量的装置和方法。 该装置包括光发射器（1），通过该光发射器可以将相干光发射到测量对象（3），接收器（2）借助于该光发射器（2），已经通过测量对象（3）的光可以是 检测和光学装置（4,5,6），借助于该装置，光发射器（1）的光强度可以瞄准接收器（2）。 根据本发明，光学装置包括透镜元件（4），其光轴相对于测量对象（3）的纵向轴线基本上倾斜地布置，使得光学边界的法线的角度相对 测量信号倾斜设定。 透镜元件（4）同时是折射和反射元件，并且将测量对象（3）与装置（1,2,5）分离。

公开(公告)号：US07391516B2

公开(公告)日：2008-06-24

申请号：US10547670

申请日：2005-03-28

Applicant: Masahiko Shioi ,  Shinji Uchida ,  Kiyoko Oshima

Inventor： Masahiko Shioi ,  Shinji Uchida ,  Kiyoko Oshima

IPC: G01N21/00 ,  G01N33/48

CPC classification number: G01N21/31 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B2562/146 ,  G01N21/01 ,  G01N21/8507 ,  G01N2021/8535 ,  G01N2201/064

Abstract: The present invention provides an optical element for measuring information of living body for noninvasively measuring a body fluid component in a test sample of living body with high accuracy, stability, and ease. The optical element includes a light incident surface, a contact surface contacting living body and having a groove to protrude living body and a light emission surface, in which a light incident from the light incident surface is applied to living body, and the light absorbed and scattered by living body is received and emitted from the light emission surface, a light transmittance controlling means is formed from the bottom part of the valley part of the groove, on at least a part of a wall surface of the light incident surface side and/or on a wall surface of the light emission surface side of the groove.

Abstract translation: 本发明提供了一种用于测量生物体的信息的光学元件，用于以高精度，稳定性和容易度非机械地测量生物体的测试样品中的体液成分。 光学元件包括光入射表面，接触表面接触生物体并具有突出的生物体的凹槽和发光表面，其中从入射表面入射的光被施加到生物体，并且光吸收和 由发光体散射的发光表面的光入射面侧的壁面的至少一部分上形成有从该凹部的谷部的底部形成的透光率控制装置和/ 或在凹槽的发光表面侧的壁表面上。

公开(公告)号：US07365849B2

公开(公告)日：2008-04-29

申请号：US11249965

申请日：2005-10-12

Applicant: Wen Fa Yao ,  Chih Ming Wang ,  Yung Chuan Liu ,  Shih Yang Lo ,  Roger Lai ,  Kuang Pin Hsiung

Inventor： Wen Fa Yao ,  Chih Ming Wang ,  Yung Chuan Liu ,  Shih Yang Lo ,  Roger Lai ,  Kuang Pin Hsiung

IPC: G01J3/46

CPC classification number: G01N21/8483 ,  G01N21/274 ,  G01N21/78 ,  G01N2021/6419 ,  G01N2021/6441 ,  G01N2021/8645 ,  G01N2021/8654 ,  G01N2201/0221 ,  G01N2201/0626 ,  G01N2201/0627 ,  G01N2201/064 ,  G01N2201/0833

Abstract: A portable, scanning and analyzing apparatus that uses an integrated scan probe for the scanning operation is described. The integrated scanning probe is formed with a light emitting diode array light source and a photodiode detector array. After a test sample finishes the reaction in test strip paper, a scanner device scans the test paper to collect the optical signals at variable, consecutive intervals along the scanning path to obtain the test signal accordingly. Then, the scanner device outputs the test signal for amplification. The amplified test signals are sent to an analog/digital converter such that the amplified test signals are converted into digital signals, which are then output to a computing unit for analyzing for subjective analytical results. The computing unit couples with the controller device, wherein the controller device controls a driver device that drives the scanner device to perform the scanning operation on the test paper.

Abstract translation: 描述了使用集成扫描探针进行扫描操作的便携式扫描和分析装置。 集成扫描探针由发光二极管阵列光源和光电二极管检测器阵列形成。 测试样品在测试条纸中完成反应后，扫描仪器将扫描测试纸，沿着扫描路径以可变的连续间隔收集光信号，从而获得相应的测试信号。 然后，扫描仪装置输出用于放大的测试信号。 放大的测试信号被发送到模拟/数字转换器，使得放大的测试信号被转换成数字信号，然后输出到计算单元以分析主观分析结果。 所述计算单元与所述控制器装置耦合，其中所述控制器装置控制驱动所述扫描仪装置以对所述测试纸进行扫描操作的驱动装置。

公开(公告)号：US20060183982A1

公开(公告)日：2006-08-17

申请号：US10547670

申请日：2005-03-28

Applicant: Masahiko Shioi

Inventor： Masahiko Shioi

IPC: A61B5/00

CPC classification number: G01N21/31 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B2562/146 ,  G01N21/01 ,  G01N21/8507 ,  G01N2021/8535 ,  G01N2201/064

Abstract: The present invention provides an optical element for measuring information of living body for noninvasively measuring a body fluid component in a test sample of living body with high accuracy, stability, and ease. The optical element includes a light incident surface, a contact surface contacting living body and having a groove to protrude living body and a light emission surface, in which a light incident from the light incident surface is applied to living body, and the light absorbed and scattered by living body is received and emitted from the light emission surface, a light transmittance controlling means is formed from the bottom part of the valley part of the groove, on at least a part of a wall surface of the light incident surface side and/or on a wall surface of the light emission surface side of the groove.

Abstract translation: 本发明提供了一种用于测量生物体的信息的光学元件，用于以高精度，稳定性和容易度非机械地测量生物体的测试样品中的体液成分。 光学元件包括光入射表面，接触表面接触生物体并具有突出的生物体的凹槽和发光表面，其中从入射表面入射的光被施加到生物体，并且光吸收和 由发光体散射的发光表面的光入射面侧的壁面的至少一部分上形成有从该凹部的谷部的底部形成的透光率控制装置和/ 或在凹槽的发光表面侧的壁表面上。

公开(公告)号：US20050078308A1

公开(公告)日：2005-04-14

申请号：US10911126

申请日：2004-08-04

Applicant: Anthony Gilby

Inventor： Anthony Gilby

IPC: G01N21/64 ,  G01N21/03 ,  G01N21/05 ,  G01N21/17 ,  G01N21/65 ,  G01N27/447 ,  G01N30/74

CPC classification number: G01N21/552 ,  G01N21/0303 ,  G01N21/05 ,  G01N30/74 ,  G01N2021/0346 ,  G01N2021/052 ,  G01N2201/064

Abstract: The present invention is directed to the use of a light absorbing wall material to eliminate stray light paths in light-guiding structures, such as those used for HPLC absorbance detection. More specifically, the present invention relates to the use of carbon-doped Teflon® AF, or “black Teflon® AF,” for all or part of the walls of a light-guiding flowcell adapted for use in HPLC absorbance detection.

Abstract translation: 本发明涉及使用光吸收壁材料来消除导光结构中的杂散光路径，例如用于HPLC吸光度检测的那些。 更具体地，本发明涉及适用于HPLC吸光度检测的导光流动池的全部或部分壁的碳掺杂特氟隆AF或“黑色特氟隆AF”的用途 。

公开(公告)号：US06809324B1

公开(公告)日：2004-10-26

申请号：US09979382

申请日：2001-11-19

Applicant: Stefan Schmidt

Inventor： Stefan Schmidt

IPC: G01N2164

CPC classification number: G01N21/6456 ,  G01N21/6458 ,  G01N2201/064 ,  G01Q60/20 ,  G02B21/16

Abstract: Optical arrangement for the suppression of stray light originating from an illuminated specimen detected via an objective, with blocking out or reflecting out in part of the beam path in order to generate a shadow area for stray light in the image plane.

Abstract translation: 用于抑制源自通过物镜检测到的照明样本的杂散光的光学布置，其阻挡或反射出部分光束路径，以便在图像平面中产生杂散光的阴影区域。