公开(公告)号：US20070030488A1

公开(公告)日：2007-02-08

申请号：US11517894

申请日：2006-09-08

Applicant: Dale Harrison

Inventor： Dale Harrison

IPC: G01N21/55

CPC classification number: G01J3/2803 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0232 ,  G01J3/027 ,  G01J3/0286 ,  G01J3/0291 ,  G01J3/08 ,  G01J3/10 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/36 ,  G01J3/42 ,  G01J3/4531 ,  G01N21/211 ,  G01N21/274 ,  G01N21/33 ,  G01N21/47 ,  G01N21/55 ,  G01N21/9501 ,  G01N2021/335

Abstract: A spectroscopy system is provided which is optimized for operation in the VUV region and capable of performing well in the DUV-NIR region. Additionally, the system incorporates an optical module which presents selectable sources and detectors optimized for use in the VUV and DUV-NIR. As well, the optical module provides common delivery and collection optics to enable measurements in both spectral regions to be collected using similar spot properties. The module also provides a means of quickly referencing measured data so as to ensure that highly repeatable results are achieved. The module further provides a controlled environment between the VUV source, sample chamber and VUV detector which acts to limit in a repeatable manner the absorption of VUV photons. The use of broad band data sets which encompass VUV wavelengths, in addition to the DUV-NIR wavelengths enables a greater variety of materials to be meaningfully characterized. Array based detection instrumentation may be exploited to permit the simultaneous collection of larger wavelength regions.

Abstract translation: 提供了一种光谱系统，其被优化用于在VUV区域中的操作并且能够在DUV-NIR区域中表现良好。 此外，该系统还包含一个光学模块，该模块提供可用于VUV和DUV-NIR中优化的可选择的源和检测器。 同样，光学模块提供通用的传送和收集光学器件，以使得能够使用类似的光点特性来收集两个光谱区域中的测量。 该模块还提供了快速参考测量数据的方法，以确保实现高度可重复的结果。 该模块还在VUV源，样品室和VUV检测器之间提供受控的环境，其作用是以可重复的方式限制VUV光子的吸收。 除了DUV-NIR波长之外，使用包含VUV波长的宽带数据集使得可以有意义地表征更多种类的材料。 可以利用基于阵列的检测仪器来允许同时收集更大的波长区域。

公开(公告)号：US06839134B2

公开(公告)日：2005-01-04

申请号：US10255623

申请日：2002-09-27

Applicant: Michihiro Saito ,  Satoshi Takahashi ,  Koichi Matsumoto

Inventor： Michihiro Saito ,  Satoshi Takahashi ,  Koichi Matsumoto

IPC: G01J3/08 ,  G01J3/44 ,  G01N21/25 ,  G01N21/64

CPC classification number: G01N21/6452 ,  G01J3/08 ,  G01J3/4406

Abstract: At the time of analytical measurement of a sample by the fluorescence measuring device or the phosphorescence measuring device, both the optical path of exciting light emitted from the light source to the sample and the optical path of fluorescence or phosphorescence emitted from the sample to the detection unit are shut off. Both are shut off by one chopper.

公开(公告)号：US20040174524A1

公开(公告)日：2004-09-09

申请号：US10796322

申请日：2004-03-09

Inventor： Adam Norton ,  Abdurrahman Sezginer ,  Fred E. Stanke ,  Rodney Smedt

IPC: G01J003/28

CPC classification number: G01J3/02 ,  G01J3/0218 ,  G01J3/08 ,  G01J3/42 ,  G01N21/55

Abstract: The invention is a method and apparatus for determining characteristics of a sample. The system and method provide for detecting a monitor beam reflected off a mirror, where the monitor beam corresponds to the intensity of light incident upon the sample. The system and method also provide for detecting a measurement beam, where the measurement beam has been reflected off the sample being characterized. Both the monitor beam and the measurement beam are transmitted through the same transmission path, and detected by the same detector. Thus, potential sources of variations between the monitor beam and the measurement beam which are not due to the characteristics of the sample are minimized. Reflectivity information for the sample can be determined by comparing data corresponding to the measurement beam relative to data corresponding the monitor beam.

Abstract translation: 本发明是用于确定样品特性的方法和装置。 该系统和方法提供用于检测从反射镜反射的监视光束，其中监视光束对应于入射在样本上的光的强度。 该系统和方法还提供了用于检测测量光束，其中测量光束已经从被表征的样品反射出来。 监测光束和测量光束都通过相同的传输路径传输，并由相同的检测器检测。 因此，监测光束和测量光束之间不是由于样品特性引起的变化的潜在来源被最小化。 可以通过将与测量光束相对应的数据相对于监视光束对应的数据进行比较来确定样本的反射率信息。

公开(公告)号：US20040008346A1

公开(公告)日：2004-01-15

申请号：US10255940

申请日：2002-09-27

Applicant: National Inst. of Advanced Ind. Science and Tech.

Inventor： Etsuo Kawate

IPC: G01J003/42

CPC classification number: G01J3/02 ,  G01J3/0208 ,  G01J3/08 ,  G01N21/41 ,  G01N21/55 ,  G01N21/59 ,  G01N2021/558

Abstract: There is provided an optical system for measurement of optical constant capable of measuring the absolute reflectance and the absolute transmittance for determining the optical constant of a substance with excellent accuracy without replacing the optical system during the measurement by using a different system for measuring the absolute reflectance and the absolute transmittance of the sample, comprising an incoming side beam switching mirror for selectively switching the direction of the light from a light source to a first or second converged light reflecting means side, first and second converged light reflecting means for projecting the light from the beam switching mirror so as to be converged in an intersecting manner at the position of a sample holder, the sample bolder capable of selectively positioning a sample fitting hole or a through hole at the converging position by the converged light reflecting means by advancing/retracting the sample fitting hole or the through hole, first and second received light reflecting means which are disposed on the optical path of the light reflected by or transmitted through a sample set in the sample fitting hole on the sample holder or the through hole, and direct the light toward a single exiting side beam switching mirror, and the exiting side beam switching mirror capable of switching the direction of the light projected via the received light reflecting means toward a single detector, and the absolute reflectance and the absolute transmittance for the face side incidence and the back side incidence of the sample.

Abstract translation: 提供了一种用于测量绝对反射率和绝对透射率的光学常数的光学系统，其用于确定物质的光学常数，而不用在测量期间使用不同的系统来测量绝对反射率 以及样品的绝对透射率，包括用于选择性地将来自光源的光的方向切换到第一或第二会聚光反射装置侧的入射侧光束切换镜，第一和第二会聚光反射装置，用于将光从 所述光束切换镜以在所述样品保持器的位置处相交的方式会聚，所述样品检测器能够通过所述会聚光反射装置通过前进/后退选择性地定位在会聚位置的样品嵌合孔或通孔 样品安装孔或通孔， 第一和第二接收光反射装置，其设置在由样本保持器或通孔上的样本装配孔中反射或透过的样本的光路上，并将光引导到单个离开侧光束切换 反射镜和能够将经由接收的光反射装置投射的光的方向朝向单个检测器切换的出射侧光束切换镜，以及样品的正面入射和背面入射的绝对反射率和绝对透射率 。

公开(公告)号：US20030160961A1

公开(公告)日：2003-08-28

申请号：US10316707

申请日：2002-12-10

Applicant: Molecular Devices Corporation

Inventor： Dean Hafeman ,  Calvin Y. Chow

IPC: G01N021/59 ,  G01N021/00

CPC classification number: G01J3/08 ,  G01J3/1804 ,  G01N21/253 ,  G01N21/31 ,  G01N21/314 ,  G01N21/6452

Abstract: Disclosed are photometric methods and devices for determining optical pathlength of liquid samples containing analytes dissolved or suspended in a solvent. The methods and devices rely on determining a relationship between the light absorption properties of the solvent and the optical pathlength of liquid samples containing the solvent. This relationship is used to establish the optical pathlength for samples containing an unknown concentration of analyte but having similar solvent composition. Further disclosed are methods and devices for determining the concentration of analyte in such samples where both the optical pathlength and the concentration of analyte are unknown. The methods and devices rely on separately determining, at different wavelengths of light, light absorption by the solvent and light absorption by the analyte. Light absorption by the analyte, together with the optical pathlength so determined, is used to calculate the concentration of the analyte. Devices for carrying out the methods particularly advantageously include vertical-beam photometers containing samples disposed within the wells of multi-assay plates, wherein the photometer is able to monitor light absorption of each sample at multiple wavelengths, including in the visible or UV-visible region of the spectrum, as well as in the near-infrared region of the electromagnetic spectrum. Novel photometer devices are described which automatically determine the concentration of analytes in such multi-assay plates directly without employing a standard curve.

公开(公告)号：US06611329B2

公开(公告)日：2003-08-26

申请号：US09437616

申请日：1999-11-10

Applicant: Glen W. Sachse

Inventor： Glen W. Sachse

IPC: G01J400

CPC classification number: G01J3/08 ,  G01N21/314 ,  G01N21/3518

Abstract: An optical path switch divides sample path radiation into a time series of alternating first polarized components and second polarized components. The first polarized components are transmitted along a first optical path and the second polarized components along a second optical path. A first gasless optical filter train filters the first polarized components to isolate at least a first wavelength band thereby generating first filtered radiation. A second gasless optical filter train filters the second polarized components to isolate at least a second wavelength band thereby generating second filtered radiation. A beam combiner combines the first and second filtered radiation to form a combined beam of radiation. A detector is disposed to monitor magnitude of at least a portion of the combined beam alternately at the first wavelength band and the second wavelength band as an indication of the concentration of the substance in the sample path.

Abstract translation: 光路开关将采样路径辐射分为交替的第一偏振分量和第二偏振分量的时间序列。 第一偏振分量沿着第一光路传播，第二偏振分量沿着第二光路传输。 第一无气体光学滤波器组对第一极化分量进行滤波以隔离至少第一波长带，从而产生第一滤波辐射。 第二无气体光学滤波器组对第二极化分量进行滤波以隔离至少第二波长带，从而产生第二滤波辐射。 光束组合器组合第一和第二滤波辐射以形成组合的辐射束。 检测器被设置为在第一波长带和第二波长带上交替地监测组合光束的至少一部分的大小作为样品路径中物质浓度的指示。

公开(公告)号：US20020030821A1

公开(公告)日：2002-03-14

申请号：US09948586

申请日：2001-09-10

Inventor： Kazumi Yokota

IPC: G01N021/59

CPC classification number: G01J3/08 ,  G01J3/28

Abstract: Time-divisionally-multiplexed light receiving signals are sampled at a predetermined time interval as they are, and then converted into digital data. Then, address is determined based on an index signal as a standard of the time-divisional multiplexing, and the data are sequentially stored in a data memory. When the data are sequentially read out, change of quantity of the data is obtained to determine a period having the smallest change in quantity as an effective period. Then, the data included in the effective period are selected and separated to a sample side beam, reference side beam and cutoff period. Thus, the multiplexed light receiving signals are accurately separated by the digital data.

Abstract translation: 时分多路复用光接收信号按预定时间间隔原样采样，然后转换为数字数据。 然后，基于作为时分复用的标准的索引信号来确定地址，并且数据被顺序地存储在数据存储器中。 当数据被顺序地读出时，获得数据量的改变以确定具有最小变化量的周期作为有效期。 然后，选择包含在有效期间的数据，并将其分离为样本侧波束，参考侧波束和截止周期。 因此，复用的光接收信号被数字数据精确地分离。

公开(公告)号：US06339472B1

公开(公告)日：2002-01-15

申请号：US09557750

申请日：2000-04-25

Applicant: Dean G. Hafeman ,  Calvin T. Chow

Inventor： Dean G. Hafeman ,  Calvin T. Chow

IPC: G01N2100

CPC classification number: G01J3/08 ,  G01J3/1804 ,  G01N21/253 ,  G01N21/31 ,  G01N21/314 ,  G01N21/6452

Abstract: Disclosed are photometric methods and devices for determining optical pathlength of liquid samples containing analytes dissolved or suspended in a solvent. The methods and devices rely on determining a relationship between the light absorption properties of the solvent and the optical pathlength of liquid samples containing the solvent. This relationship is used to establish the optical pathlength for samples containing an unknown concentration of analyte but having similar solvent composition. Further disclosed are methods and devices for determining the concentration of analyte in such samples where both the optical pathlength and the concentration of analyte are unknown. The methods and devices rely on separately determining, at different wavelengths of light, light absorption by the solvent and light absorption by the analyte. Light absorption by the analyte, together with the optical pathlength so determined, is used to calculate the concentration of the analyte. Devices for carrying out the methods particularly advantageously include vertical-beam photometers containing samples disposed within the wells of multi-assay plates, wherein the photometer is able to monitor light absorption of each sample at multiple wavelengths, including in the visible or UV-visible region of the spectrum, as well as in the near-infrared region of the electromagnetic spectrum. Novel photometer devices are described which automatically determine the concentration of analytes in such multi-assay plates directly without employing a standard curve.

Abstract translation: 公开了用于确定含有溶解或悬浮在溶剂中的分析物的液体样品的光程长度的光度测定方法和装置。 所述方法和装置依赖于确定溶剂的光吸收性质和含有溶剂的液体样品的光程长度之间的关系。 该关系用于建立含有未知浓度的分析物但具有相似溶剂组成的样品的光程。 进一步公开了用于确定样品中分析物浓度的方法和装置，其中光程长和分析物浓度都是未知的。 方法和装置依赖于在不同波长的光下分别确定溶剂的光吸收和被分析物的光吸收。 被分析物的光吸收以及如此确定的光程长度被用于计算分析物的浓度。 用于实施方法的装置特别有利地包括垂直光束光度计，其包含设置在多测定板的孔内的样品，其中光度计能够监测包括在可见光或可见光区域中的多个波长的每个样品的光吸收 的光谱，以及在电磁光谱的近红外区域。 描述了新的光度计装置，其直接在不使用标准曲线的情况下自动确定这种多测定板中的分析物的浓度。

公开(公告)号：US5815263A

公开(公告)日：1998-09-29

申请号：US865868

申请日：1997-05-30

Applicant: Masumi Sakai

Inventor： Masumi Sakai

IPC: G01J3/08 ,  G01J3/42

CPC classification number: G01J3/08 ,  G01J3/42

Abstract: A double-beam spectrophotometer of the invention is provided with a sector mirror used at a luminous flux separating portion or at a luminous flux combining portion, and a DC brushless motor is used for actuating the sector mirror to rotate. Since the DC brushless motor is used, the sector mirror can be rotated at high speed with few noise. Also, the double-beam spectrophotometer can measure the change in the short period of time.

Abstract translation: 本发明的双光束分光光度计具有在光束分离部分或光束组合部分处使用的扇形镜，并且DC无刷电动机用于致动扇形镜转动。 由于使用了直流无刷电动机，扇形镜可以高速旋转，噪音小。 此外，双光束分光光度计可以测量短时间内的变化。

公开(公告)号：US5652654A

公开(公告)日：1997-07-29

申请号：US689391

申请日：1996-08-12

Applicant: George Asimopoulos

Inventor： George Asimopoulos

IPC: G01J3/08 ,  G01J3/28 ,  G01J3/42 ,  G01J3/18

CPC classification number: G01J3/2889 ,  G01J3/08 ,  G01J3/42 ,  G01J2003/2866

Abstract: A dual beam spectophotometer is described in which a beamsplitter is at least partially surrounded by a chopper, the combination of which provide sample and reference beams. An oscillating grating produces a monochromatic light beam scans a selected spectral range of wavelengths. The movement of a second chopper and of the oscillating grating is controlled to alternately pass sample and reference spectrums for detection by a detector and to block all radiation. Detected signals are processed for storage by suitable electronics and a computer. The electronics also control the motion of the oscillating grating and chopper. A set of beamsplitters with distinctly different sample-to-reference beam ratios are provided to add versatility to the spectrophotometer.

Abstract translation: 描述了一种双光束光谱仪，其中分束器至少部分地由斩波器包围，其组合提供了采样和参考光束。 振荡光栅产生单色光束扫描所选择的波长范围。 控制第二斩波器和振荡光栅的移动以交替地通过采样和参考光谱，以便由检测器检测并阻止所有辐射。 检测到的信号由适当的电子设备和计算机进行处理。 电子设备还可以控制振荡光栅和斩波器的运动。 提供了一组具有明显不同的样品与参比光束比的分光镜，以增加分光光度计的多功能性。