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    PARALLEL HAPTIC JOYSTICK SYSTEM
    273.
    发明申请
    PARALLEL HAPTIC JOYSTICK SYSTEM 审中-公开
    平行玩具系统

    公开(公告)号：WO2004104814A1

    公开(公告)日：2004-12-02

    申请号：PCT/KR2003/002047

    申请日：2003-10-02

    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  KIM, Munsang ,  RYU, Dongseok ,  CHO, Changhyun ,  HWANG, Chang-soon

    Inventor： KIM, Munsang ,  RYU, Dongseok ,  CHO, Changhyun ,  HWANG, Chang-soon

    IPC: G06F3/033

    CPC classification number: G06F3/016 ,  G05G7/02 ,  G05G9/04737 ,  G06F3/0338 ,  G06F3/0346

    Abstract: The present invention relates to a haptic joystick system that is used with a computer system. The system according to the present invention includes the mechanism comprising the first link work and the second link work that respectively conduct 3 degree-of-freedom independently and are serially connected to each other. Therefore the said mechanism conducts 6 degree-of-freedom. The said mechanism is provided at its base plane with sensors and actuators, whereby not being affected by the inertia of the sensors and the actuators. Also, in the system according to the present invention, the first link work conducts 3 degree-of-freedom among the overall 6 degree-of-freedom that are frequently used in its application, and the second link work conducts another 3 degree-of-freedom. Thereby, the system according to the present invention can achieve the enhanced performance related to the energy effectiveness and the controllability.

    Abstract translation: 本发明涉及一种与计算机系统一起使用的触觉操纵杆系统。 根据本发明的系统包括包括分别独立地并且彼此串联连接的3个独立自由度的第一链接工作和第二链接工作的机构。 所以这个机制是6度自由的。 所述机构在其基面设置有传感器和致动器，由此不受传感器和致动器的惯性的影响。 此外，在本发明的系统中，第一连接工​​作在其应用中经常使用的整体6自由度之间进行3自由度，第二连接工作传导另外3度 -自由。 因此，根据本发明的系统可以实现与能量效率和可控性相关的增强的性能。

    METHOD FOR DECREASING DEPRESSION BY INHIBITING THE ACTIVITY OF N-TYPE CALCIUM CHANNEL
    275.
    发明申请
    METHOD FOR DECREASING DEPRESSION BY INHIBITING THE ACTIVITY OF N-TYPE CALCIUM CHANNEL 审中-公开
    通过抑制N型钙通道的活性来减少呕吐的方法

    公开(公告)号：WO2004035087A1

    公开(公告)日：2004-04-29

    申请号：PCT/KR2003/002159

    申请日：2003-10-16

    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  SHIN, Hee-Sup ,  KIM, Chanki

    Inventor： SHIN, Hee-Sup ,  KIM, Chanki

    IPC: A61K39/395

    CPC classification number: C07K14/705

    Abstract: The present invention relates to the method for decreasing depression, more particularly to the method for decreasing depression by inhibiting the activity of N-type calcium channel. According to the present invention, inhibiting material of N-type calcium channel activity can effectively be used for the depression remedy. Also, anti-depression reagent can be screened using N-type calcium channel.

    Abstract translation: 本发明涉及减轻抑郁症的方法，更具体地说，涉及通过抑制N-型钙通道的活性来抑制抑郁症的方法。 根据本发明，抑制N型钙通道活性的材料可以有效地用于抑郁症。 此外，可以使用N型钙通道筛选抗抑郁药。

    MUCOADHESIVE COMPOSITION AND FORMULATION FOR SOLUBILIZATION OF INSOLUBLE DRUGS AND PREPARATION METHOD THEREOF
    276.
    发明申请
    MUCOADHESIVE COMPOSITION AND FORMULATION FOR SOLUBILIZATION OF INSOLUBLE DRUGS AND PREPARATION METHOD THEREOF 审中-公开
    用于溶解不溶性药物的组合物和制剂及其制备方法

    公开(公告)号：WO2004009122A1

    公开(公告)日：2004-01-29

    申请号：PCT/KR2003/001443

    申请日：2003-07-21

    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  CHUNG, Hesson ,  JEONG, Seo-Young ,  KWON, Ick-Chan ,  PARK, Yeong-Taek ,  LEE, In-Hyun

    Inventor： CHUNG, Hesson ,  JEONG, Seo-Young ,  KWON, Ick-Chan ,  PARK, Yeong-Taek ,  LEE, In-Hyun

    IPC: A61K47/44

    CPC classification number: A61K9/006 ,  A61K9/0019 ,  A61K9/1075 ,  A61K31/225 ,  A61K47/14 ,  A61K47/44

    Abstract: The present invention relates to a novel mucoadhesive composition for solubilization of insoluble drugs; its formulation including pharmaceutical compounds; and the preparation methods thereof wherein said solubilizing composition comprises 4~90% by weight of at least one selected from the monoglycerides and 0.01~90% by weight of at least one oil. The present invention relates to a novel mucoadhesive composition including pharmaceutical compounds; and the preparation methods thereof wherein said solubilizing composition including emulsifiers is composed of 4~90% by weight of at least one selected from the monoglycerides, 0.01~90% by weight, of at least one oil, and 0.01~90% by weight of at least one selected from the emulsifiers. The compositions of the present invention is suitable as drug delivery systems since they exist as mucoadhesive liquid at physiological temperatures even though they exist as liquid or semi-solid at room temperature.

    Abstract translation: 本发明涉及一种用于溶解不溶性药物的新型粘膜粘附组合物， 其制剂包括药物化合物; 及其制备方法，其中所述增溶组合物包含4〜90重量％的选自单酸甘油酯和0.01〜90重量％的至少一种油的至少一种。 本发明涉及包含药物化合物的新型粘膜粘附组合物; 及其制备方法，其中所述包含乳化剂的增溶组合物由4〜90重量％的选自单酸甘油酯，0.01〜90重量％，至少1种油和0.01〜90重量％ 选自乳化剂中的至少一种。 本发明的组合物适合作为药物递送系统，因为它们在生理温度下作为粘膜粘附液体存在，即使它们在室温下以液体或半固体形式存在。

    MEMBRANELESS AND MEDIATORLESS MICROBIAL FUEL CELL
    277.
    发明申请
    MEMBRANELESS AND MEDIATORLESS MICROBIAL FUEL CELL 审中-公开
    无菌和无介质微生物燃料电池

    公开(公告)号：WO2003096467A1

    公开(公告)日：2003-11-20

    申请号：PCT/KR2003/000950

    申请日：2003-05-14

    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  KIM, Byung Hong ,  CHANG, In Seop ,  JANG, Jae Kyung ,  GIL, Geun Cheol

    Inventor： KIM, Byung Hong ,  CHANG, In Seop ,  JANG, Jae Kyung ,  GIL, Geun Cheol

    IPC: H01M8/16

    CPC classification number: H01M8/16 ,  H01M4/86 ,  H01M4/92 ,  H01M4/926 ,  H01M8/0234 ,  H01M8/08 ,  Y02E60/527

    Abstract: Disclosed is a mediator-less microbial fuel cell comprising a cathode compartment, an anode compartment, with or without glass wool and glass bead for separating the two compartments, an element for feeding air to the cathode compartment, and an element for feeding wastewater to the anode compartment. The cell further comprises an element for controlling the distance between the cathode compartment and the anode compartment. Graphite felt or graphite felt coated with a metal such as platinum is used as an electrode of the cathode compartment, and a buffer solution is used in the anode compartment. A mediator-less microbial fuel cell according to the present invention can be operated without using an expensive cation-exchange membrane, of which efficiency is by no means inferior to prior wastewater treatment methods.

    Abstract translation: 公开了一种无中介的微生物燃料电池，其包括阴极室，具有或不具有玻璃棉的阳极室和用于分离两个室的玻璃珠，用于将空气供入阴极室的元件和用于将废水送入 阳极室。 电池还包括用于控制阴极室和阳极室之间的距离的元件。 用金属如铂的石墨毡或石墨毡用作阴极室的电极，在阳极室中使用缓冲溶液。 根据本发明的无介体的微生物燃料电池可以在不使用昂贵的阳离子交换膜的情况下操作，其效率绝不逊于现有的废水处理方法。

    HETERODIMERIC CONJUGATES OF NEOMYCIN-OXAZOLIDINONE, THEIR PREPARATION AND THEIR USE
    278.
    发明申请
    HETERODIMERIC CONJUGATES OF NEOMYCIN-OXAZOLIDINONE, THEIR PREPARATION AND THEIR USE 审中-公开
    神经毒素 - 奥昔洛芬的非球形连接，其制备及其使用

    公开(公告)号：WO2003066648A1

    公开(公告)日：2003-08-14

    申请号：PCT/KR2002/001268

    申请日：2002-07-04

    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  YU, Jaehoon ,  LEE, Jongkook ,  KWON, Miyun ,  PAE, Ae,Nim ,  KOH, Hun,Yeong

    Inventor： YU, Jaehoon ,  LEE, Jongkook ,  KWON, Miyun ,  PAE, Ae,Nim ,  KOH, Hun,Yeong

    IPC: C07H15/22

    CPC classification number: C07H15/232

    Abstract: The present invention relates to heterodimeric conjugates of neomycin-oxazolidinone of formula 1, their preparation and their use. Because of their heterodimeric structure, they can recognize both stems and loops of the RNA motif and show a strong binding force to certain RNAs. Accordingly, they can be effectively used as an antiviral agent or an antibacterial agent with enhanced pharmaceutical efficacy and reduced side effect. Formula (I) Wherein, Ac and n are as defined in the description.

    Abstract translation: 本发明涉及式1的新霉素 - 恶唑烷酮的异二聚体缀合物，其制备及其用途。 由于它们的异二聚体结构，它们可以识别RNA基序的茎和环，并且对某些RNA显示出强的结合力。 因此，它们可以有效地用作具有增强的药物功效和降低副作用的抗病毒剂或抗菌剂。 式（I）其中Ac和n如说明书中所定义。

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