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公开(公告)号：US20160313342A1
公开(公告)日：2016-10-27
申请号：US15103539
申请日：2014-12-11
Inventor： Kenji Hamase , Yurika MIYOSHI , Masashi MITA
IPC: G01N33/68
CPC classification number: G01N33/6812 , G01N2800/347
Abstract: The present invention addresses the problem of identifying a biomarker of renal failure, said biomarker being available from urine or blood, and fluctuating from an early stage than glomerular filtration rate and serum creatinine level, and thus developing a technique for diagnosing early stage kidney failure. A method for analyzing the blood, plasma, serum or urine of a renal failure suspected subject comprises a step of measuring the concentration of a pair of D-form and L-form of at least one amino acid selected from the amino acid group consisting of [D-serine] and [L-serine], etc., contained in the blood, plasma, serum or urine of the subject, and calculating, as an pathological index of the subject, the ratio of the D-form concentration to the L-form concentration or the percentage of the D-form concentration relative to the total concentration of the D-form and L-form.
Abstract translation: 本发明解决了鉴定肾衰竭的生物标志物的问题，所述生物标志物可从尿液或血液中获得，并且从早期阶段比肾小球滤过率和血清肌酐水平波动，从而开发用于诊断早期肾衰竭的技术。 用于分析肾衰竭疑似受试者的血液，血浆，血清或尿液的方法包括测量一对D型和L型的至少一种氨基酸的浓度的步骤，所述氨基酸选自由以下组成的氨基酸组： [D-丝氨酸]和[L-丝氨酸]等，包含在受试者的血液，血浆，血清或尿液中，并计算作为受试者的病理学指标，D型浓度与 L型浓度或D-型浓度相对于D-型和L-型总浓度的百分比。
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公开(公告)号：US20160310403A1
公开(公告)日：2016-10-27
申请号：US15099737
申请日：2016-04-15
Applicant: SHISEIDO COMPANY, LTD.
Inventor： KAZUTAKA SASAKI
CPC classification number: A61K8/87 , A61K8/0216 , A61K8/022 , A61K8/85 , A61K2800/26 , A61Q19/00 , A61Q19/008
Abstract: An aqueous skin cosmetic product exerting a high irregularity correction effect, providing a non-greasy and light feeling when applied and having an excellent sebum suppressing effect is provided. The skin cosmetic product of the present invention is characterized by comprising (A) 15 to 50% by mass of a powder formed of an (adipic acid/neopentyl glycol) crosspolymer and (B) 0.5 to 3% by mass of a hydrophobically modified polyurethane. (PEG-240/Decyltetradeceth-20/HDI) copolymer is preferable as the hydrophobically modified polyurethane, It is preferable that the skin cosmetic product is a gel having a viscosity of 15,000 mPa·s or more and 200,000 mPa·s or less.
Abstract translation: 提供具有高不规则矫正效果的水性皮肤化妆品，在使用时提供非油腻感和具有优异的皮脂抑制作用。 本发明的皮肤化妆品的特征在于，包含（A）15质量％〜50质量％的由（己二酸/新戊二醇）交联聚合物形成的粉末，（B）0.5〜3质量％的疏水改性聚氨酯 。 （PEG-240 /癸基十四碳烯-20 / HDI）共聚物优选作为疏水改性聚氨酯。优选皮肤化妆品为粘度为15000mPa·s以上且200,000mPa·s以下的凝胶。
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公开(公告)号：US09364423B2
公开(公告)日：2016-06-14
申请号：US13954176
申请日：2013-07-30
Applicant: Shiseido Company, Ltd.
Inventor： Rikako Suzuki , Kiyotaka Hasegawa , Kiyoshi Sato , Tokiya Yokoi , Ken Kusakari
Abstract: The present invention is directed to an extrace of Psilotum spp., as a skin whitening agent. Whitening agents according to the invention exhibit superior effects, for example, by lightening and whitening skin pigmentation, lightening and whitening aging spots, freckles, chloasma, or the like after sunburn. The Psilotum spp. extract of the invention has a superior free radical scavenging ability permitting the extract to control skin aging and skin diseases caused by active oxygen (free radicals), while having a high level of safety.
Abstract translation: 本发明涉及Psilotum spp。作为皮肤增白剂。 根据本发明的美白剂显示出优异的效果，例如通过在晒伤后减轻和增白皮肤色素沉着，减轻和增白老化点，雀斑，黄褐斑等。 Psilotum属 本发明的提取物具有优异的自由基清除能力，其允许提取物控制皮肤老化和由活性氧（自由基）引起的皮肤疾病，同时具有高水平的安全性。
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274.发明申请公开(公告)号：US20160063312A1
公开(公告)日：2016-03-03
申请号：US14779722
申请日：2014-02-27
Applicant: SHISEIDO COMPANY, LTD.
Inventor： Yusuke HARA , Ichiro IWAI , Hiroyuki OHNISHI
CPC classification number: G06K9/00268 , A61B5/0077 , A61B5/1079 , A61B5/1128 , A61B5/442 , A61B5/7271 , A61B34/10 , A61B90/361 , G06K9/00315 , G06K9/46 , G06K2009/4666 , G06T7/20 , G06T7/248 , G06T2207/30088
Abstract: An image analysis apparatus that analyzes a skin condition from a video of the face of a subject captured with an imaging part includes a tracking part configured to track the amount of changes of multiple tracking points arranged in advance in an analysis region of the face based on a change in the expression of the face included in the video, and obtain the compression ratio of the skin in the analysis region based on the amount of changes, and a skin condition analysis part configured to analyze the skin condition of the subject based on the compression ratio obtained by the tracking part.
Abstract translation: 一种从成像部件拍摄的被摄体的脸部的视频中分析皮肤状况的图像分析装置包括跟踪部件，其被配置为基于在所述脸部的分析区域中预先设置的多个跟踪点的变化量，基于 包括在视频中的脸部表情的变化，并且基于变化量获得分析区域中的皮肤的压缩比，以及皮肤状况分析部件，被配置为基于所述皮肤状况分析对象的皮肤状况 由跟踪部获得的压缩比。
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公开(公告)号：US20160058679A1
公开(公告)日：2016-03-03
申请号：US14785880
申请日：2014-02-03
Applicant: SHISEIDO COMPANY LTD.
Inventor： TETSURO YONEZAWA
CPC classification number: A61K8/14 , A61K8/03 , A61K8/062 , A61K8/31 , A61K8/44 , A61K8/553 , A61K8/60 , A61K8/86 , A61K8/894 , A61K8/922 , A61K2800/592 , A61Q19/00
Abstract: The present invention provides an aqueous composition in which vesicles and oil drops are stably coexistent.The aqueous composition of the present invention is characterized by containing (a) an amphiphilic compound, (b) water, and (c) oil, wherein vesicles formed with component (a) and oil drops containing component (c) are present in component (b).
Abstract translation: 本发明提供一种其中囊泡和油滴稳定共存的水性组合物。 本发明的水性组合物的特征在于含有（a）两亲性化合物，（b）水和（c）油，其中由组分（a）形成的泡沫和含有组分（c）的油滴存在于组分（ b）。
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Patent Agency Ranking
276.发明申请公开(公告)号：US20160039743A1
公开(公告)日：2016-02-11
申请号：US14918743
申请日：2015-10-21
Inventor： Masashi MITA , Kenji HAMASE , Tsubasa OYAMA
IPC: C07C227/36
CPC classification number: C07C227/36 , C07C227/34 , C07D215/22 , C07D401/12 , C07C229/08
Abstract: Disclosed is a compound represented by chemical formula (1): or chemical formula (2):
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277.发明申请公开(公告)号：US20160035109A1
公开(公告)日：2016-02-04
申请号：US14783159
申请日：2014-03-24
Applicant: SHISEIDO COMPANY, LTD.
Inventor： Kumiko KIKUCHI , Yuji MASUDA
CPC classification number: G06T7/90 , A61B5/1032 , A61B5/107 , A61B5/441 , G06K9/4652 , G06K2009/4666 , G06T7/0012 , G06T2207/30088
Abstract: A skin dullness evaluation apparatus includes a frequency analyzing unit that decomposes a skin image into color heterogeneity of a predetermined size; a color heterogeneity index obtaining unit that obtains color data of skin from each of the color heterogeneity decomposed by the frequency analyzing unit, and obtains a color heterogeneity index of the color heterogeneity from the obtained color data of skin; and a dullness evaluation unit that evaluates skin dullness corresponding to the skin image based on the color heterogeneity index obtained by the color heterogeneity index obtaining unit.
Abstract translation: 皮肤暗淡评估装置包括频率分析单元，其将皮肤图像分解成具有预定尺寸的颜色异质性; 从所述频率分析单元分解的每个颜色异质性中获得皮肤的颜色数据的颜色异质性指标获取单元，并从所获得的皮肤颜色数据中获得颜色异质性的颜色异质性指数; 以及基于由所述颜色异质性指标获取单元获得的颜色异质性指数来评估与所述皮肤图像相对应的皮肤暗淡的浊度评估单元。
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278.发明申请METHOD FOR EVALUATING STATE OF HORNY LAYER AND METHOD FOR EVALUATING HORNY LAYER IMPROVEMENT EFFECT OF COSMETIC PREPARATION 有权用于评价嗅层状态的方法和评估胭脂红层的改进方法化妆品制备的影响公开(公告)号：US20150362412A1
公开(公告)日：2015-12-17
申请号：US14761386
申请日：2014-01-21
Applicant: SHISEIDO COMPANY, LTD.
Inventor： Eiichiro YAGI , Ichiro IWAI
CPC classification number: G01N1/30 , A61B5/442 , A61B5/443 , A61B5/4848 , A61K8/498 , A61K2800/434 , A61Q19/00 , G01N33/5088 , G01N33/52 , G01N2001/302
Abstract: The invention relates to providing a method for more conveniently evaluating stratum corneum condition. A stratum corneum sheet is contacted with a solution of a water-soluble dye, and the staining intensity or fluorescence intensity is measured to allow convenient evaluation of the stratum corneum condition. There is further provided a method for evaluating the ameliorating effect of a cosmetic or cosmetic treatment on the stratum corneum, by implementing the method for evaluating stratum corneum condition using a water-soluble dye according to the invention.
Abstract translation: 本发明涉及提供一种更方便地评价角质层状况的方法。 将角质层与水溶性染料的溶液接触，测定染色强度或荧光强度，以方便评价角质层状况。 还提供了一种通过实施根据本发明的水溶性染料来评估角质层状况的方法来评价化妆品或美容处理对角质层的改善效果的方法。
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279.发明授权Compound, optical resolution method, and derivative of an optical isomer of an amino acid 有权化合物，光学拆分方法和氨基酸的光学异构体的衍生物公开(公告)号：US09193684B2
公开(公告)日：2015-11-24
申请号：US14472920
申请日：2014-08-29
Inventor： Masashi Mita , Kenji Hamase , Tsubasa Oyama
IPC: C07D215/22 , C07D401/12 , C07C227/34
CPC classification number: C07C227/36 , C07C227/34 , C07D215/22 , C07D401/12 , C07C229/08
Abstract: Disclosed is a compound represented by chemical formula (1): or chemical formula (2):
Abstract translation: 公开了由化学式（1）表示的化合物：或化学式（2）：
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公开(公告)号：US20150328124A1
公开(公告)日：2015-11-19
申请号：US14650769
申请日：2013-07-01
Applicant: SHISEIDO COMPANY, LTD.
Inventor： Takayuki OMURA , Daisuke SUZUKI
CPC classification number: A61K8/37 , A61K8/062 , A61K8/34 , A61K8/345 , A61K8/735 , A61K8/8152 , A61K8/8158 , A61K8/86 , A61K8/891 , A61K2800/59 , A61Q19/00 , A61Q19/007 , A61Q19/08
Abstract: The present invention provides an oil-in-water emulsion composition that is high in the moisturizing effect and the skin smoothing effect, excellent in the improving effect on wrinkles and elasticity, good in spreadability during application, and without an oily feeling and sticky feeling.The oil-in-water emulsion composition of the present invention is characterized by comprising the below-described components (a) hyaluronic acid or a salt thereof, (b) ammonium acryloyldimethyltaurate/beheneth-25 methacrylate crosspolymer, (c) water-holding oil, (d) glycerin, and (e) ethanol.
Abstract translation: 本发明提供一种油包水乳液组合物，其具有高的保湿效果和皮肤光滑效果，对皱纹和弹性的改善效果优异，涂布时的铺展性好，无油感和粘稠感。 本发明的水包油型乳液组合物的特征在于，含有下述成分（a）透明质酸或其盐，（b）丙烯酰基二甲基牛磺酸铵/山梨醇-25甲基丙烯酸酯交联聚合物，（c）保水油 ，（d）甘油和（e）乙醇。
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