公开(公告)号：US20180064851A1

公开(公告)日：2018-03-08

申请号：US15698429

申请日：2017-09-07

Applicant: Case Western Reserve University ,  Worcester Polytechnic Institute

Inventor： Eben Alsberg ,  Anna D. Dikina ,  Marsha W. Rolle ,  Hannah A. Strobel

IPC: A61L27/38 ,  A61K35/42 ,  A61L27/58 ,  A61K35/32

CPC classification number: A61L27/3817 ,  A61K35/28 ,  A61K35/32 ,  A61K35/42 ,  A61K35/44 ,  A61L27/3804 ,  A61L27/3839 ,  A61L27/3886 ,  A61L27/54 ,  A61L27/58 ,  A61L2300/414 ,  A61L2300/62 ,  A61L2400/12 ,  A61L2430/02 ,  C12M21/08 ,  C12M25/14 ,  C12N5/0655 ,  C12N5/0697 ,  C12N2533/30

Abstract: A modular engineered tissue construct includes a plurality of fused self-assembled, scaffold-free, high-density cell aggregates. At least one cell aggregate includes a plurality of cells and a plurality of biocompatible and biodegradable nanoparticles and/or microparticles that are incorporated within the cell aggregates. The nanoparticles and/or microparticles acting as a bulking agent within the cell aggregate to increase the cell aggregate size and/or thickness and improve the mechanical properties of the cell aggregate as well as to deliver bioactive agents.

公开(公告)号：US09846042B2

公开(公告)日：2017-12-19

申请号：US14940704

申请日：2015-11-13

Applicant: Worcester Polytechnic Institute

Inventor： Benzun Wisely Babu ,  David Cyganski ,  R. James Duckworth

IPC: G01C21/20 ,  G01C21/18 ,  G05D1/02 ,  G06T7/80 ,  G06T7/246

CPC classification number: G01C21/206 ,  G01C21/18 ,  G05D1/0251 ,  G05D1/027 ,  G05D1/0274 ,  G06T7/246 ,  G06T7/85 ,  G06T2207/10012 ,  G06T2207/30244

Abstract: An indoor localization system uses Visual Simultaneous Localization and Mapping (VSLAM) aided by gyroscope sensor information. Indoor environments pose several challenges which could cause a vision only system to fail due to tracking errors. Investigation revealed significant feature loss in a vision only system when traversing plain walls, windows and staircases. However, the addition of a gyroscope helps in handling such difficult conditions by providing additional rotational information. A portable system consisting of an Inertial Measurement Unit (IMU) and a stereo camera has been developed for indoor mapping. The images and gyroscope rates acquired by the system are stored and post-processed using Gyroscope Assisted Scalable Visual Simultaneous Localization and Mapping Algorithm.

公开(公告)号：US20170322629A1

公开(公告)日：2017-11-09

申请号：US15586684

申请日：2017-05-04

Applicant: Worcester Polytechnic Institute

Inventor： Saraj Pirasmepulkul ,  Alexander Caracappa ,  Peerapat Luxsuwong ,  Cagdas D. Onal ,  William Michalson ,  Tri Khuu ,  Ming Luo

IPC: G06F3/01 ,  G06F3/0484

CPC classification number: G06F3/016 ,  G06F3/011 ,  G06F3/014 ,  G06F3/017 ,  G06F3/0346 ,  G06F3/0484 ,  G06F2203/0383 ,  G10H2220/311 ,  G10H2220/321

Abstract: A toroidal actuator is responsive to a teleoperator for providing haptic feedback responsive to a curvature or articulated movement applied to a gripped object. The toroidal actuator surrounds an operator member such as a finger, and is responsive to pneumatic pressure for increasing telepresence force defined by resistance encounter against a teleoperated robotic claw. As the teleoperated claw grips an object, increased pneumatic pressure in the toroidal actuator tends to elongate the toroidal shape in a linear manner and oppose a curvature force applied by an inserted operator finger. Resistive force is based on soft sensing of the gripped object, thus the toroidal actuator applies an increasing resistive force to curvature as the robotic claw closes around a gripped object by solenoid regulated air pressure. A typical assembly includes at least 3 toroidal actuators for two digits and a thumb of an operator.

公开(公告)号：US20170308104A1

公开(公告)日：2017-10-26

申请号：US15492161

申请日：2017-04-20

Applicant: Worcester Polytechnic Institute

Inventor： Richard T. Eberheim ,  Nicholas F. Hassan ,  Joshua C. O'Connor

IPC: G05D1/10 ,  B64C39/02 ,  B64C31/02 ,  B64D45/04 ,  B64B1/46

Abstract: The airborne vehicle recovery method and apparatus enables radiosonde users to reliably recover launched radiosondes and provides new and unique opportunities for research and data acquisition with balloon launched radiosondes. Airborne vehicles such as radiosondes are disposed in a flight body adapted for propulsionless, gliding navigation for returning to one of several designated landing sites for recovery. Onboard electronics including a navigation computer, flight computer, and lightweight battery are employed for selecting a landing site, computing a heading and direction, and actuating flaps for pursuing a propulsionless, gliding path to the landing site. Gliding is directed only by right and left flaps responsive to respective actuators, such that the inclusion of only the actuators, navigation and flight electronics, and without active propulsion, enables sufficient gliding range from the lightweight construction and arrangement to reach one of several landing sites for effecting substantial recovery rates of the radiosondes.

公开(公告)号：US20170296159A1

公开(公告)日：2017-10-19

申请号：US15491107

申请日：2017-04-19

Applicant: Worcester Polytechnic Institute ,  University of Massachusetts

Inventor： Jacquelyne DiTroia ,  Caroline Mazzola ,  Andres Monterroso ,  Patricia Swierk ,  Kristen Billiar ,  Arriyan Samandar Dowlatshahi ,  Raymond M. Dunn

IPC: A61B17/02 ,  A61B17/32 ,  A61B17/00

CPC classification number: A61B17/0206 ,  A61B2017/00407 ,  A61B2017/00902 ,  A61B2017/00911 ,  A61B2017/0092 ,  A61B2017/320044

Abstract: A surgical appliance includes a pair of opposed prongs slideably disposed on an elongated locking track for retracting neurovascular and musculotendinous anatomical structures through an incision for affording access to deeper structures for inserting osteosynthesis hardware in the surgical treatment of a distal radius fracture or other surgical procedure. The prongs extend from retractors that traverse the locking track for opposed linear movement while recessed in a surgical working region accessible through an incision. The prongs terminate in curvatures defining a void that gather and engage the elongated anatomical structures on top of the skeletal members receiving the plate. The prongs draw back the tendons, blood vessels and nerve structures to allow unimpeded surgical access for manipulating and attaching skeletal and soft tissue members and/or appliances. The device retracts anatomical structures along a linear track for a fixed locking engagement maintaining a surgical gap without direct manual assistance.

公开(公告)号：US20170296139A1

公开(公告)日：2017-10-19

申请号：US15488364

申请日：2017-04-14

Applicant: Worcester Polytechnic Institute ,  University of Massachusetts

Inventor： Dennis Giaya ,  Rebecca Stolarczyk ,  Yitzhak Mendelson ,  Arriyan Samandar Dowlatshahi ,  Raymond Dunn

IPC: A61B8/06 ,  A61B8/00 ,  A61B5/026 ,  G01S15/89 ,  A61B5/055 ,  G01S7/52

CPC classification number: A61B8/06 ,  A61B5/0022 ,  A61B5/0084 ,  A61B5/01 ,  A61B5/02007 ,  A61B5/02055 ,  A61B5/022 ,  A61B5/02416 ,  A61B5/026 ,  A61B5/0261 ,  A61B5/055 ,  A61B5/4244 ,  A61B5/445 ,  A61B5/6847 ,  A61B8/0883 ,  A61B8/0891 ,  A61B8/12 ,  A61B8/4455 ,  A61B8/4494 ,  A61B8/461 ,  A61B8/463 ,  A61B8/488 ,  A61B8/5223 ,  G01S7/52023 ,  G01S15/8979 ,  G16H40/67

Abstract: The present invention relates to devices and methods for measuring vascular deficiency using Doppler ultrasound detection. Embodiments can be used to monitor the condition of surgical tissue flaps or other conditions in which obstruction in the vascular system can impact patient health. The systems can include a Doppler ultrasound probe, a color probe, a temperature probe, and/or other suitable probes to measure blood volume and perfusion status of a tissue region. The systems and methods can be used to monitor flaps after flap transplant surgeries. The systems and methods can automatedly assess tissue condition and alert the patient or medical staff if the condition has fallen below a threshold indicating occlusion of a blood vessel. One or more additional sensors can be integrated into a probe to measure vascular conditions and a metric can be computed based on sensed data.

公开(公告)号：US20170266474A1

公开(公告)日：2017-09-21

申请号：US15475684

申请日：2017-03-31

Applicant: Worcester Polytechnic Institute

Inventor： Brian E. Elias ,  Robert G. Zalosh ,  Ali S. Rangwala ,  Samim Safaei Boroojeny

IPC: A62C3/06

CPC classification number: A62C3/065 ,  A62C4/00

Abstract: A volatile liquid storage container has combustion resistance properties from a flexible sock or tube constructed of fire resistant fibers coupled to a neck of the storage container to prevent flame flash-back into the storage container. The storage container defines an enclosed volume having an orifice in the container material leading to a neck for pouring and filling the enclosed volume for exchanging the contents therein. The tube is elongated and surrounds a circumference of the orifice for engaging any ignition source entering through the orifice. The flexible nature of the tube or sock allows it to extend to an opposed interior surface of the enclosed volume, and ensures that the tube or sock is immersed in the fluid for encircling any ignition path to the volatile liquid without interfering with an ability to pour or refill the container.

公开(公告)号：US20170180382A1

公开(公告)日：2017-06-22

申请号：US15381712

申请日：2016-12-16

Applicant: Worcester Polytechnic Institute

Inventor： Curtis R. Taylor ,  Craig A. Shue

IPC: H04L29/06

CPC classification number: H04L63/0272 ,  H04L12/2803 ,  H04L63/0281 ,  H04L63/101

Abstract: A service provider device includes a controller having a memory and a processor. The controller is configured to receive a device access request from the client device via a residential network, the server provider device being located external to the residential network and detect a communication type identifier associated with the device access request. The controller is configured to establish a secure communication channel between the client device and a middlebox associated with the detected communication type identifier and provide communication between the client device and the server device via the secure communication channel between the client device.

公开(公告)号：US20170103671A1

公开(公告)日：2017-04-13

申请号：US15388295

申请日：2016-12-22

Applicant: Worcester Polytechnic Institute

Inventor： Janice D. Gobert ,  Michael A. Sao Pedro ,  Cameron Guerra Betts ,  Ryan S. Baker

IPC: G09B19/00 ,  G09B7/02 ,  G06N5/02 ,  G09B5/02

CPC classification number: G09B19/00 ,  G06N5/022 ,  G06N5/025 ,  G06Q10/06398 ,  G09B5/00 ,  G09B5/02 ,  G09B7/02

Abstract: An assessment engine includes a definition of inquiry skills being assessed. Assessment models are used to infer skill demonstration as one or more students engage in inquiry within computerized simulations and/or microworlds. A pedagogical agent and/or help system provides real-time feedback to one or more students based on the assessment model outputs, and/or based on additional models that track one or more students developing proficiency across inquiry tasks over time. A pedagogical agent and/or help system for science inquiry tutoring responds in real-time on the basis of knowledge-engineered and data-mined assessment and/or tracking models.

公开(公告)号：US20170092831A1

公开(公告)日：2017-03-30

申请号：US15278201

申请日：2016-09-28

Applicant: Worcester Polytechnic Institute

Inventor： Steven Van Dessel

IPC: H01L35/24 ,  H01L35/32

CPC classification number: H01L35/24 ,  H01L35/32

Abstract: A molecular thermoelectric (M-TE) lipid layer includes a lipid bilayer or monolayer and a dopant, and in particular, the dopant can be an n-type dopant, a p-type dopant, or a hybrid thereof. The dopant can be selected from modified biological molecules, such as lipid, transmembrane protein and oligonucleotides. A molecular thermoelectric (M-TE) lipid device can incorporate the molecular thermoelectric (M-TE) lipid layer.