公开(公告)号：US20180178174A1

公开(公告)日：2018-06-28

申请号：US15886212

申请日：2018-02-01

Applicant: Raindance Technologies, Inc.

Inventor： Darren Roy Link ,  Michael Weiner ,  David Marran ,  Jonathan M. Rothberg

IPC: B01F3/08 ,  G01N35/08 ,  G01N27/327 ,  B01F13/00 ,  B01J19/00 ,  G01N21/05 ,  G01N21/64 ,  B01L3/00 ,  B03C5/00 ,  B03C5/02 ,  C12N15/10 ,  C12Q1/00 ,  C12Q1/6806 ,  C12Q1/6837 ,  C12Q1/6844 ,  C12Q1/6855 ,  C12Q1/6869 ,  C12Q1/6874 ,  G01N15/14 ,  B01L9/00 ,  B01L7/00 ,  G01N21/03 ,  G01N35/00

CPC classification number: B01F3/0807 ,  B01F13/0062 ,  B01J19/0093 ,  B01L3/502715 ,  B01L3/502746 ,  B01L3/502784 ,  B01L3/565 ,  B01L7/525 ,  B01L9/527 ,  B01L2200/027 ,  B01L2200/0636 ,  B01L2200/0647 ,  B01L2200/0673 ,  B01L2200/10 ,  B01L2300/0636 ,  B01L2300/0816 ,  B01L2300/0861 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/165 ,  B01L2400/0415 ,  B01L2400/0424 ,  B01L2400/0487 ,  B01L2400/086 ,  B03C5/005 ,  B03C5/026 ,  C12N15/1068 ,  C12N15/1086 ,  C12Q1/00 ,  C12Q1/6806 ,  C12Q1/6837 ,  C12Q1/6844 ,  C12Q1/6855 ,  C12Q1/6869 ,  C12Q1/6874 ,  C12Q2565/628 ,  C12Q2565/629 ,  G01N15/147 ,  G01N21/05 ,  G01N21/64 ,  G01N27/3275 ,  G01N35/08 ,  G01N2021/0346 ,  G01N2035/00237 ,  G01N2035/00326 ,  G01N2201/024 ,  Y10T137/87571 ,  Y10T137/87619 ,  Y10T137/87652 ,  C12Q2525/191 ,  C12Q2563/159 ,  C12Q2535/101 ,  C12Q2563/149 ,  C12Q2531/113

Abstract: The present invention provides novel microfluidic substrates and methods that are useful for performing biological, chemical and diagnostic assays. The substrates can include a plurality of electrically addressable, channel bearing fluidic modules integrally arranged such that a continuous channel is provided for flow of immiscible fluids.

公开(公告)号：US09981230B2

公开(公告)日：2018-05-29

申请号：US13779943

申请日：2013-02-28

Applicant: RainDance Technologies, Inc.

Inventor： Darren R. Link ,  Michael Weiner ,  David Marran ,  Jonathan M. Rothberg

IPC: C12Q1/68 ,  C12P19/34 ,  B01F3/08 ,  B01F13/00 ,  B01J19/00 ,  B01L3/00 ,  B03C5/00 ,  B03C5/02 ,  C12Q1/00 ,  G01N15/14 ,  G01N21/05 ,  G01N21/64 ,  G01N35/08 ,  G01N27/327 ,  C12N15/10 ,  B01L7/00 ,  B01L9/00 ,  G01N35/00 ,  G01N21/03

CPC classification number: B01F3/0807 ,  B01F13/0062 ,  B01J19/0093 ,  B01L3/502715 ,  B01L3/502746 ,  B01L3/502784 ,  B01L3/565 ,  B01L7/525 ,  B01L9/527 ,  B01L2200/027 ,  B01L2200/0636 ,  B01L2200/0647 ,  B01L2200/0673 ,  B01L2200/10 ,  B01L2300/0636 ,  B01L2300/0816 ,  B01L2300/0861 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/165 ,  B01L2400/0415 ,  B01L2400/0424 ,  B01L2400/0487 ,  B01L2400/086 ,  B03C5/005 ,  B03C5/026 ,  C12N15/1068 ,  C12N15/1086 ,  C12Q1/00 ,  C12Q1/6806 ,  C12Q1/6837 ,  C12Q1/6844 ,  C12Q1/6855 ,  C12Q1/6869 ,  C12Q1/6874 ,  C12Q2565/628 ,  C12Q2565/629 ,  G01N15/147 ,  G01N21/05 ,  G01N21/64 ,  G01N27/3275 ,  G01N35/08 ,  G01N2021/0346 ,  G01N2035/00237 ,  G01N2035/00326 ,  G01N2201/024 ,  Y10T137/87571 ,  Y10T137/87619 ,  Y10T137/87652 ,  C12Q2525/191 ,  C12Q2563/159 ,  C12Q2535/101 ,  C12Q2563/149 ,  C12Q2531/113

Abstract: The present invention provides novel microfluidic substrates and methods that are useful for performing biological, chemical and diagnostic assays. The substrates can include a plurality of electrically addressable, channel bearing fluidic modules integrally arranged such that a continuous channel is provided for flow of immiscible fluids.

公开(公告)号：US20180113068A1

公开(公告)日：2018-04-26

申请号：US15570958

申请日：2015-07-24

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Timothy L. Weber

IPC: G01N21/05 ,  G01N21/64 ,  G01N21/59 ,  G01N21/11

CPC classification number: G01N21/05 ,  B01L3/50273 ,  B01L2300/0816 ,  B01L2400/0442 ,  G01N21/11 ,  G01N21/59 ,  G01N21/6428 ,  G01N2021/0328 ,  G01N2021/0346 ,  G01N2021/6439 ,  G01N2021/7783 ,  G01N2021/7786 ,  G01N2201/0221 ,  G01N2201/024 ,  G01N2201/0873

Abstract: In one example, testing cells extend along a length of a slot. Each testing cell includes a microfluidic channel extending from the slot, a pump to move fluid from the slot into the channel, a discharge nozzle through which fluid exits the channel, a fluid discharger to discharge fluid from the channel through the nozzle and a photosensor. A light guide is provided to receive light from an external light source and is to serially transmit the light to the microfluidic channel of each of the plurality of testing cells.

公开(公告)号：US09903807B2

公开(公告)日：2018-02-27

申请号：US15211140

申请日：2016-07-15

Applicant: HON HAI PRECISION INDUSTRY CO., LTD.

Inventor： Jen-Tsorng Chang

IPC: G01J3/46 ,  G01N21/25 ,  A61B5/00 ,  G01N33/493 ,  G01N33/49

CPC classification number: G01N21/251 ,  A61B5/0002 ,  A61B5/0022 ,  G01N21/8483 ,  G01N33/49 ,  G01N33/493 ,  G01N2021/8488 ,  G01N2201/0221 ,  G01N2201/024

Abstract: A wearable device includes a testing portion, the testing portion includes receiving space, a bottom surface defining an opening, an opposite top surface, and a first side surface defining a slot. A white light source is received in the receiving space. A wearable portion of the device is secured to the testing portion and the wearable portion can be placed around a terminal device comprising a camera. The opening faces the camera when the wearable portion is around the terminal device, allowing the camera to capture a standard image of the white light, and capture a wet image of a test paper imbued with user bio-matter when the test paper is inserted into the slot. A biological information of the user, as an indicator of health, is calculated according to a color comparison between the wet image and the standard image.

公开(公告)号：US09891197B2

公开(公告)日：2018-02-13

申请号：US15259312

申请日：2016-09-08

Applicant: VUV Analytics, Inc.

Inventor： Dale A. Harrison ,  Anthony T. Hayes ,  Phillip Walsh

IPC: G01N21/00 ,  G01N30/78 ,  G01N21/05 ,  G01N21/33 ,  G01J3/02 ,  G01N30/02 ,  G01N30/74 ,  G01N33/00 ,  G01N21/15 ,  G01N21/03

CPC classification number: G01N30/78 ,  G01J3/02 ,  G01N21/0332 ,  G01N21/05 ,  G01N21/15 ,  G01N21/33 ,  G01N30/02 ,  G01N30/74 ,  G01N33/0004 ,  G01N33/0027 ,  G01N2021/0325 ,  G01N2021/151 ,  G01N2021/158 ,  G01N2021/335 ,  G01N2030/025 ,  G01N2030/027 ,  G01N2201/024 ,  G01N2201/0633 ,  G01N2201/12 ,  G01N30/7266

Abstract: An efficient absorption spectroscopy system is provided. The spectroscopy system may be configured to measure solid, liquid or gaseous samples. Vacuum ultra-violet wavelengths may be utilized. Some of the disclosed techniques can be used for detecting the presence of trace concentrations of gaseous species. A preferable gas flow cell is disclosed. Some of the disclosed techniques may be used with a gas chromatography system so as to detect and identify species eluted from the column. Some of the disclosed techniques may be used in conjunction with an electrospray interface and a liquid chromatography system so as to detect and identify gas phase ions of macromolecules produced from solution. Some of the disclosed techniques may be used to characterize chemical reactions. Some of the disclosed techniques may be used in conjunction with an ultra short-path length sample cell to measure liquids.

公开(公告)号：US09804085B2

公开(公告)日：2017-10-31

申请号：US14670958

申请日：2015-03-27

Applicant: Fondarex S.A.

Inventor： Konrad Baumgartner ,  Yves Gerard Laurent Huguenin-Vuillemin

IPC: B22D2/00 ,  B22D17/14 ,  B22D17/20 ,  B22D17/32 ,  G01N21/3554 ,  G01N21/3504 ,  G01N21/85 ,  B22C9/06 ,  G01N21/15 ,  B29C45/34 ,  G01N21/359 ,  B29C45/76 ,  G01N21/84

CPC classification number: G01N21/3554 ,  B22C9/067 ,  B22D17/145 ,  B22D17/2007 ,  B22D17/32 ,  B29C45/34 ,  B29C45/76 ,  B29C2945/7614 ,  B29C2945/76254 ,  G01N21/15 ,  G01N21/3504 ,  G01N21/359 ,  G01N21/85 ,  G01N2021/151 ,  G01N2021/354 ,  G01N2021/8416 ,  G01N2021/8578 ,  G01N2201/024 ,  G01N2201/062 ,  G01N2201/0622 ,  G01N2201/0626 ,  G01N2201/064

Abstract: A device and a method are provided for measuring the moisture in die cast molds, the cavity of which is connected via an evacuation conduit to an evacuation device. The modular assembly of the device is connectable to the evacuation conduit and includes a sensor assembly to measure the moisture of gases evacuated from the mold cavity. The sensor assembly includes an emitter emitting electromagnetic radiation and a detector detecting electromagnetic radiation. On the basis of the measured values obtained during the evacuation action it can be determined whether the amount of a water/release agent mixture jetted into the mold cavity needs to be altered before the actual casting action.

公开(公告)号：US20170268992A1

公开(公告)日：2017-09-21

申请号：US15462021

申请日：2017-03-17

Applicant: Dräger Safety AG & Co. KGaA

Inventor： Patrick SCHMIDT-KAEDING

IPC: G01N21/3504

CPC classification number: G01N21/3504 ,  G01N21/09 ,  G01N2021/0314 ,  G01N2021/3513 ,  G01N2201/0227 ,  G01N2201/024 ,  G01N2201/086

Abstract: An in-situ gas-measuring system (1) includes an IR photon source (10) and an IR photon detector (11). The in-situ gas-measuring system (1) has an expansion chamber (12), at which an optical element (16, 16′, 16″) is arranged. A connection element (13) provides a detachable fluid-communicating connection of the expansion chamber (12) to a gas reaction chamber (2). The IR-photon source (10), the optical element (16, 16′, 16″) and the IR photon detector (11) define an optical measuring path, which extends through the expansion chamber (12). The installation and maintenance of the in-situ gas-measuring system (1) are reduced by the features of the in-situ gas-measuring system (1).

公开(公告)号：US20160377581A1

公开(公告)日：2016-12-29

申请号：US15259361

申请日：2016-09-08

Applicant: VUV Analytics, Inc.

Inventor： Dale A. Harrison ,  Anthony T. Hayes ,  Phillip Walsh, JR.

IPC: G01N30/74 ,  G01N21/33

CPC classification number: G01N30/78 ,  G01J3/02 ,  G01N21/0332 ,  G01N21/05 ,  G01N21/15 ,  G01N21/33 ,  G01N30/02 ,  G01N30/74 ,  G01N33/0004 ,  G01N33/0027 ,  G01N2021/0325 ,  G01N2021/151 ,  G01N2021/158 ,  G01N2021/335 ,  G01N2030/025 ,  G01N2030/027 ,  G01N2201/024 ,  G01N2201/0633 ,  G01N2201/12 ,  G01N30/7266

Abstract: An efficient absorption spectroscopy system is provided. The spectroscopy system may be configured to measure solid, liquid or gaseous samples. Vacuum ultra-violet wavelengths may be utilized. Some of the disclosed techniques can be used for detecting the presence of trace concentrations of gaseous species. A preferable gas flow cell is disclosed. Some of the disclosed techniques may be used with a gas chromatography system so as to detect and identify species eluted from the column. Some of the disclosed techniques may be used in conjunction with an electrospray interface and a liquid chromatography system so as to detect and identify gas phase ions of macromolecules produced from solution. Some of the disclosed techniques may be used to characterize chemical reactions. Some of the disclosed techniques may be used in conjunction with an ultra short-path length sample cell to measure liquids.

公开(公告)号：US20160265974A1

公开(公告)日：2016-09-15

申请号：US14641912

申请日：2015-03-09

Applicant: Corning Incorporated

Inventor： John Phillip Ertel ,  Jeffrey Stapleton King

IPC: G01J3/427 ,  G01J3/18 ,  G01J3/26

CPC classification number: G01J3/427 ,  G01J3/0205 ,  G01J3/0237 ,  G01J3/0256 ,  G01J3/0259 ,  G01J3/0264 ,  G01J3/0272 ,  G01J3/0291 ,  G01J3/18 ,  G01J3/1895 ,  G01J3/26 ,  G01N21/31 ,  G01N21/43 ,  G01N21/552 ,  G01N21/648 ,  G01N2201/0221 ,  G01N2201/024

Abstract: A spectrophotometer optics system is provided. The spectrophotometer optics system includes an optical sensing array and an optical waveguide including an input side and an output side. The input side of the optical waveguide receives input light and the optical sensing array is located at the output side of optical waveguide. The optical waveguide is configured to carry light to be analyzed by total internal reflection to the output side of the optical waveguide and to direct the light to be analyzed toward the optical sensing array. The spectrophotometer optics system includes an optical dispersive element configured to separate the light to be analyzed into separate wavelength components, and the optical dispersive element is supported by the optical waveguide.

Abstract translation: 提供分光光度计光学系统。 分光光度计光学系统包括光学感测阵列和包括输入侧和输出侧的光波导。 光波导的输入侧接收输入光，光感测阵列位于光波导的输出侧。 光波导被配置为将通过全内反射分析的光携带到光波导的输出侧，并将待分析的光引导到光学感测阵列。 分光光度计光学系统包括被配置为将要分析的光分离成分离的波长分量的光学色散元件，并且光学色散元件由光波导支撑。

公开(公告)号：US20160069921A1

公开(公告)日：2016-03-10

申请号：US14872995

申请日：2015-10-01

Applicant: Theranos, Inc.

Inventor： Elizabeth A. Holmes ,  Michael Chen

IPC: G01N35/10

CPC classification number: G01N35/0092 ,  B01L3/021 ,  B01L3/5082 ,  B01L7/52 ,  B01L9/06 ,  B01L9/52 ,  B01L9/543 ,  B01L2300/1827 ,  B01L2300/1855 ,  C12Q1/42 ,  C12Q1/52 ,  C12Q1/6883 ,  C12Q1/70 ,  G01N15/1475 ,  G01N21/25 ,  G01N21/27 ,  G01N33/5005 ,  G01N33/54306 ,  G01N33/54313 ,  G01N33/54366 ,  G01N33/56983 ,  G01N33/62 ,  G01N33/6827 ,  G01N33/80 ,  G01N33/92 ,  G01N35/00 ,  G01N35/00029 ,  G01N35/00069 ,  G01N35/00623 ,  G01N35/00871 ,  G01N35/026 ,  G01N35/04 ,  G01N35/10 ,  G01N35/1009 ,  G01N35/1011 ,  G01N35/1065 ,  G01N35/1072 ,  G01N2015/0073 ,  G01N2015/008 ,  G01N2015/1006 ,  G01N2015/1486 ,  G01N2035/00138 ,  G01N2035/00148 ,  G01N2035/00237 ,  G01N2035/00306 ,  G01N2035/00326 ,  G01N2035/00356 ,  G01N2035/00366 ,  G01N2035/00425 ,  G01N2035/00435 ,  G01N2035/00495 ,  G01N2035/00633 ,  G01N2035/0449 ,  G01N2035/0474 ,  G01N2035/0486 ,  G01N2035/0491 ,  G01N2035/0493 ,  G01N2035/0494 ,  G01N2201/024 ,  G01N2201/04 ,  G01N2201/12 ,  Y10T436/111666 ,  Y10T436/113332

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.