公开(公告)号：KR1020110004961A

公开(公告)日：2011-01-17

申请号：KR1020090062406

申请日：2009-07-09

Applicant: 피씨엘 (주) ,  고려대학교 산학협력단

Inventor： 이광렬 ,  이명훈

IPC: G01N33/553 ,  B82B3/00 ,  G01N33/532

Abstract: PURPOSE: A method for labeling and detecting a target material using metal-coated superparamagnetic nanoparticles is provided to specifically detect environmental hormone and biomass without separate fluorescence microscope. CONSTITUTION: A method for labeling a target material using metal-coated superparamagnetic nanoparticles comprises: a step of conjugating a ferromagnetic substance particles to the target materials; a step of adding superparamagnetic nanoparticles to attach to the ferromagnetic substance. The diameter of the ferromagnetic substance is 5nm to 10 um. The metal is able to cause surface Plasmon resonance in case of irradiating light. The metal is Au or Ag. The superparamagnetic nanoparticles are iron-oxide, iron-cobalt, iron-nickel or transition metal.

Abstract translation: 目的：提供使用金属涂层超顺磁性纳米粒子标记和检测靶材料的方法，用于在不使用荧光显微镜的情况下，特异性地检测环境激素和生物质。 构成：使用金属涂覆的超顺磁性纳米颗粒标记靶材料的方法包括：将铁磁性物质颗粒与目标材料共轭的步骤; 添加超顺磁性纳米粒子附着于铁磁物质的步骤。 铁磁物质的直径为5nm至10μm。 在照射光时，金属能够引起表面等离子体共振。 金属是Au或Ag。 超顺磁性纳米颗粒是氧化铁，铁 - 钴，铁 - 镍或过渡金属。