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    One-step flow control for crossing channels
    21.
    发明申请
    One-step flow control for crossing channels 失效
    跨越通道的一步式流量控制

    公开(公告)号：US20100140517A1

    公开(公告)日：2010-06-10

    申请号：US12329550

    申请日：2008-12-06

    Applicant: Emmanuel Delamarche

    Inventor： Emmanuel Delamarche

    IPC: F16K31/08

    CPC classification number: F16K99/0001 ,  F16K31/086 ,  F16K99/0046 ,  F16K2099/0084 ,  Y10T137/2213

    Abstract: In one embodiment of the present invention, an apparatus for one-step flow control at a micro-channel crossing comprises a first micro-channel and a second micro-channel, a plurality of magnetic valves, and a guiding magnet. The guiding magnet produces a proximal magnetic field gradient at a location of each of the plurality of magnetic valves when an operator places the guiding magnet in a vicinity of the chip. The vicinity of the chip comprises a plurality of guiding magnet position ranges. The operator repositions guiding magnet in order to actuate the plurality of magnetic valves simultaneously. Depending on the position of the guiding magnet, the passages are blocked or unblocked to stop or let the fluid flow in a given crossing.

    Abstract translation: 在本发明的一个实施例中，用于微通道交叉的一步流量控制的装置包括第一微通道和第二微通道，多个电磁阀和引导磁体。 当操作者将引导磁体放置在芯片附近时，引导磁体在多个电磁阀的每一个的位置处产生近端磁场梯度。 芯片附近包括多个引导磁体位置范围。 操作者重新引导磁体以同时致动多个电磁阀。 取决于导向磁体的位置，通道被阻塞或不阻挡以停止或使流体在给定的横穿中流动。

    Magnetically actuated microfluidic mixers
    22.
    发明申请
    Magnetically actuated microfluidic mixers 失效
    磁致动微流体混合器

    公开(公告)号：US20100139797A1

    公开(公告)日：2010-06-10

    申请号：US12329549

    申请日：2008-12-06

    Applicant: Emmanuel Delamarche

    Inventor： Emmanuel Delamarche

    IPC: B81B7/02 ,  F15C3/06

    CPC classification number: B01F13/0059 ,  B01F5/0611 ,  B01F5/0647 ,  B01F5/0681 ,  B01L3/502738 ,  B01L2400/0633 ,  Y10T137/2076 ,  Y10T137/2093 ,  Y10T137/2191 ,  Y10T137/2202 ,  Y10T137/2213 ,  Y10T137/2218

    Abstract: In one embodiment as described in this section, an apparatus for mixing of microfluidic streams on a chip is presented, which comprises a micro-channel and a plurality of magnetic valves on the chip. A guiding magnet produces a proximal magnetic field gradient to exert a force on a bead in a cavity when placed at in a vicinity of the chip. The bead-cavity combination form a magnetic valve. In one embodiment, the mouth of the cavity is tapered so to prevent the magnetic bead from completely blocking the corresponding micro-channel section to enhance the mixing of microfluidic streams at the narrowed fluid path. In one embodiment, magnetically actuated valves direct the flow in a microfluidic system in one of several flow paths wherein the mixing characteristics of the paths are different.

    Abstract translation: 在本节所述的一个实施例中，提供了一种用于在芯片上混合微流体流的装置，其包括芯片上的微通道和多个电磁阀。 当放置在芯片附近时，导向磁体产生近端磁场梯度以在空腔中的珠上施加力。 珠 - 腔组合形成一个电磁阀。 在一个实施例中，空腔的口是锥形的，以防止磁珠完全阻挡相应的微通道部分，以增强微流体流在变窄流体路径处的混合。 在一个实施例中，磁力驱动的阀将微流体系统中的流引导到几个流动路径之一中，其中路径的混合特性不同。

    Method and device for flowing a liquid on a surface
    24.
    发明授权
    Method and device for flowing a liquid on a surface 有权
    用于在表面上流动液体的方法和装置

    公开(公告)号：US07329111B2

    公开(公告)日：2008-02-12

    申请号：US10537238

    申请日：2003-11-13

    Applicant: Emmanuel Delamarche ,  David Juncker ,  Bruno Michel ,  Heinz Schmid

    Inventor： Emmanuel Delamarche ,  David Juncker ,  Bruno Michel ,  Heinz Schmid

    IPC: B21C3/00

    CPC classification number: B01L3/0262 ,  B01J2219/00369 ,  B01J2219/0038 ,  B01J2219/0043 ,  B01L3/5027 ,  B01L2200/025 ,  B01L2300/0809 ,  B01L2300/089 ,  B01L2300/10 ,  B01L2400/022 ,  B01L2400/0403 ,  B01L2400/0406 ,  B01L2400/0415 ,  B01L2400/0487 ,  B05C5/02 ,  C40B60/14 ,  Y10T137/9682 ,  Y10T436/2575

    Abstract: A device for flowing a liquid on a surface comprises: a flow path. A first port supplies the liquid to one end of the flow path and applies a first port pressure for retaining the liquid when the flow path is remote from the surface. A second port receives the liquid from the other end of the flow path and applies a second port pressure such that the difference between the first and second negative port pressures is oriented to promote flow of the liquid from the first port to the second port via the flow path in response to the flow path being located proximal to the surface and the liquid in the device contacting the surface. The first and second port pressures are such that the liquid is drawn towards at least the second port in response to withdrawal of the flow path from the surface. Such devices may employ microfluidic technology and find application in surface patterning.

    Abstract translation: 用于在表面上流动液体的装置包括：流动路径。 第一端口将液体供应到流路的一端，并且当流动路径远离表面时施加用于保持液体的第一端口压力。 第二端口从流动路径的另一端接收液体并施加第二端口压力，使得第一和第二负压力压力之间的差定向为促进液体从第一端口流经第二端口经由 响应于流动路径位于表面附近的流动路径以及与表面接触的装置中的液体。 第一和第二端口压力使得响应于流动路径从表面的撤回而将液体吸向至少第二端口。 这样的装置可以采用微流控技术并在表面图案化中找到应用。

    Surface treatment
    25.
    发明申请
    Surface treatment 有权
    表面处理

    公开(公告)号：US20070015153A1

    公开(公告)日：2007-01-18

    申请号：US10539726

    申请日：2003-11-13

    Applicant: Sergey Amontov ,  Emmanuel Delamarche ,  Bruno Michel

    Inventor： Sergey Amontov ,  Emmanuel Delamarche ,  Bruno Michel

    IPC: C12Q1/68 ,  C12P19/34 ,  H01L21/00 ,  H01L51/30

    CPC classification number: G01N33/54366

    Abstract: A method for producing a monolayer of molecules on a surface comprises: loading a stamp with seed molecules; transferring seed molecules from the stamp to the surface; and, amplifying the seed molecules via an amplifying reaction to produce the monolayer. The method permit generation of complete monolayers from incomplete or sparse monolayers initially printed on the surface.

    Abstract translation: 在表面上产生单层分子的方法包括：用种子分子装载印模; 将种子分子从印模转移到表面; 并通过扩增反应扩增种子分子以产生单层。 该方法允许从最初印刷在表面上的不完全或稀疏单层产生完整的单层。

    Method and device for flowing a liquid on a surface
    26.
    发明申请
    Method and device for flowing a liquid on a surface 有权
    用于在表面上流动液体的方法和装置

    公开(公告)号：US20060093697A1

    公开(公告)日：2006-05-04

    申请号：US10537238

    申请日：2003-11-13

    Applicant: Emmanuel Delamarche ,  David Juncker ,  Bruno Michel ,  Heinz Schmid

    Inventor： Emmanuel Delamarche ,  David Juncker ,  Bruno Michel ,  Heinz Schmid

    IPC: B29C67/00

    CPC classification number: B01L3/0262 ,  B01J2219/00369 ,  B01J2219/0038 ,  B01J2219/0043 ,  B01L3/5027 ,  B01L2200/025 ,  B01L2300/0809 ,  B01L2300/089 ,  B01L2300/10 ,  B01L2400/022 ,  B01L2400/0403 ,  B01L2400/0406 ,  B01L2400/0415 ,  B01L2400/0487 ,  B05C5/02 ,  C40B60/14 ,  Y10T137/9682 ,  Y10T436/2575

    Abstract: A device for flowing a liquid on a surface comprises: a flow path. A first port supplies the liquid to one end of the flow path and applies a first port pressure for retaining the liquid when the flow path is remote from the surface. A second port receives the liquid from the other end of the flow path and applies a second port pressure such that the difference between the first and second negative port pressures is oriented to promote flow of the liquid from the first port to the second port via the flow path in response to the flow path being located proximal to the surface and the liquid in the device contacting the surface. The first and second port pressures are such that the liquid is drawn towards at least the second port in response to withdrawal of the flow path from the surface. Such devices may employ microfluidic technology and find application in surface patterning.

    Abstract translation: 用于在表面上流动液体的装置包括：流动路径。 第一端口将液体供应到流路的一端，并且当流动路径远离表面时施加用于保持液体的第一端口压力。 第二端口从流动路径的另一端接收液体并施加第二端口压力，使得第一和第二负压力压力之间的差定向为促进液体从第一端口流经第二端口经由 响应于流动路径位于表面附近的流动路径以及与表面接触的装置中的液体。 第一和第二端口压力使得响应于流动路径从表面的撤回而将液体吸向至少第二端口。 这样的装置可以采用微流控技术并在表面图案化中找到应用。

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