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公开(公告)号：WO2020081353A1
公开(公告)日：2020-04-23
申请号：PCT/US2019/055580
申请日：2019-10-10
Applicant: INCOM, INC.
Inventor： WELKER, David
Abstract: A method of making a transverse Anderson localization (TAL) element includes mixing pellets together to make a mixture, the pellets being of two or more distinct materials having respective wave speeds effective to provide Anderson guiding. The mixture is fused to make a preform which has respective pellet-size areas of the distinct materials corresponding to the pellets in the mixture. One or more stretching operations is performed to stretch the preform into the TAL element.
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公开(公告)号：WO2017015216A1
公开(公告)日：2017-01-26
申请号：PCT/US2016/042815
申请日：2016-07-18
Applicant: INCOM, INC.
Inventor： WELKER, David James , DAVIDSON, Eric Robert , BAUR, Kristopher Alan , NELSEN, Stephan Patrick , DEBLANDER, Evan Franklin , WELKER, Zachary David
IPC: G02B6/10 , G02B6/255 , C03B37/023 , G01T1/20
CPC classification number: B29D11/00682 , B29K2025/04 , B29K2033/12 , G01T1/201 , G02B6/00 , G02B6/02
Abstract: A wave guide face plate for transmitting an image formed in a scintillating material included as part of a transmitting medium is disclosed. The transmitting medium includes a random distribution of different refractive index regions in two orthogonal dimensions, and an essentially consistent refractive index in a third orthogonal dimension. The third orthogonal direction is aligned with a transmission axis of the wave transmitter extending from an input location to a wave detector location. The transmission efficiency of the wave guide faceplate is improved in situations where the entry angle of the input radiation is different from the axis of the wave transmitter as compared to conventional faceplates.
Abstract translation: 公开了一种用于传输形成在作为传输介质的一部分的闪烁材料中形成的图像的波导面板。 发送介质包括两个正交尺寸的不同折射率区域的随机分布，以及在第三正交维度中基本一致的折射率。 第三正交方向与从输入位置延伸到波检测器位置的波发射器的透射轴对准。 与常规面板相比，输入辐射的入射角与波发射器的轴不同的情况下，波导面板的传输效率得到改善。
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公开(公告)号：WO1988010241A1
公开(公告)日：1988-12-29
申请号：PCT/US1987001557
申请日：1987-06-26
Applicant: INCOM, INC. , JESKEY, Richard, V. , PLOCHARCZYK, John, R.
Inventor： INCOM, INC.
IPC: C03B37/027
CPC classification number: C03B37/02718 , C03B37/028 , C03B37/029 , C03B2205/56 , C03B2205/63 , C03B2205/74 , C03B2205/80 , C03B2205/81 , C03B2205/91 , C03B2205/98 , Y02P40/57
Abstract: Control of speed and uniformity of the heating of the working zone of the preform in a glass drawing operation in which the softening heat is applied by forced convection (13), using a separate fluid heating zone to introduce temperature and velocity controlled fluid. The size of the working zone is further controlled by changing (18) the configuration of a movable exit sleeve. Uniformity and accuracy of temperature is enhanced by normalization (10) of the temperature of the preform close to a preselected value before the preform enters the furnace. A glass drawing apparatus embodies the preferred means to carry out the process, providing a two-chamber furnace having an air heating chamber (44) connected by air delivery channels (51) to a drawing chamber (43). The drawing chamber has preform inlet (41) and a drawn product outlet (56). Each of the latter preferably has an adjustable opening diameter. The inlet is provided with a pre-cooling collar (35). The outlet has an insulated, movable sleeve (62) controlling the effective distance from the inlet to the outlet by modifying the temperature gradient. The latter provides means for controlling the length and shape of the working zone (55).
Abstract translation: 在通过强制对流（13）施加软化热的玻璃拉拔操作中，使用单独的流体加热区引入温度和速度受控流体来控制预成型件的工作区域的加热速度和均匀性。 通过改变（18）可移动出口套筒的构造来进一步控制工作区域的尺寸。 温度的均匀性和准确性通过在预成型坯进入炉之前接近预定值的预成型件的温度归一化（10）来提高。 玻璃拉伸装置体现了实施该方法的优选方式，提供了一个具有通过空气输送通道（51）连接到拉伸室（43）连接的空气加热室（44）的双室炉。 拉伸室具有预成型件入口（41）和拉制产品出口（56）。 后者优选具有可调开口直径。 入口设有预冷套环（35）。 出口具有绝缘的可移动套管（62），通过改变温度梯度来控制从入口到出口的有效距离。 后者提供用于控制工作区（55）的长度和形状的装置。
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公开(公告)号：WO2007056490A3
公开(公告)日：2007-05-18
申请号：PCT/US2006/043571
申请日：2006-11-08
Applicant: INCOM, INC. , MINOT, Michael, J. , STOWE, David, W.
Inventor： MINOT, Michael, J. , STOWE, David, W.
Abstract: The present invention provides a substrate that overcomes the performance limitations of conventional microscope slides, microarrays, or microtiter plates when optically interrogated through the thickness of the substrate. With conventional microscope slides, image quality and resolution are degraded as a result of distortions introduced by imaging through the thickness of the glass. Fiber Optic Interrogated Microslides (FOI) consist of many fiber optics that have been fused together. When sliced and polished to form microscope slides, the fibers effectively transfer optical images from one surface of the microslide to the other. The finished microslide is the optical equivalent of a zero thickness window. The image of an object on the top surface is transferred to the bottom surface allowing it to be viewed without focusing through the thickness of the slide. In addition to providing improved image quality, FOI microslides allow objects to be directly imaged without complex and expensive focusing optics .
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25.发明申请
公开(公告)号：WO2007056490A2
公开(公告)日：2007-05-18
申请号：PCT/US2006043571
申请日：2006-11-08
Applicant: INCOM INC , MINOT MICHAEL J , STOWE DAVID W
Inventor： MINOT MICHAEL J , STOWE DAVID W
IPC: C12M3/00
Abstract: The present invention provides a substrate that overcomes the performance limitations of conventional microscope slides, microarrays, or microtiter plates when optically interrogated through the thickness of the substrate. With conventional microscope slides, image quality and resolution are degraded as a result of distortions introduced by imaging through the thickness of the glass. Fiber Optic Interrogated Microslides (FOI) consist of many fiber optics that have been fused together. When sliced and polished to form microscope slides, the fibers effectively transfer optical images from one surface of the microslide to the other. The finished microslide is the optical equivalent of a zero thickness window. The image of an object on the top surface is transferred to the bottom surface allowing it to be viewed without focusing through the thickness of the slide. In addition to providing improved image quality, FOI microslides allow objects to be directly imaged without complex and expensive focusing optics .
Abstract translation: 本发明提供了当通过基底的厚度进行光学询问时克服了常规显微镜载玻片，微阵列或微量滴定板的性能限制的基底。 使用传统的显微镜载玻片，由于通过玻璃的厚度成像引入的失真，图像质量和分辨率降低。 光纤询问微滑石（FOI）由许多融合在一起的光纤组成。 当切片和抛光以形成显微镜载玻片时，纤维有效地将光学图像从微滑块的一个表面传递到另一个表面。 完成的微滑坡是零厚度窗口的光学等效物。 上表面上的物体的图像被转移到底部表面，使得它能够被观察而不聚焦穿过滑块的厚度。 除了提供改进的图像质量之外，FOI微滑镜允许物体直接成像，而无需复杂且昂贵的聚焦光学元件。
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Patent Agency Ranking
公开(公告)号：WO2005069971A2
公开(公告)日：2005-08-04
申请号：PCT/US2005002087
申请日：2005-01-24
Applicant: INCOM INC , MINOT MICHAEL J , DETARANDO MICHAEL A , KASS JASON
Inventor： MINOT MICHAEL J , DETARANDO MICHAEL A , KASS JASON
CPC classification number: G02B6/08 , B01L3/502707 , B01L3/502715 , B01L3/5085 , B01L2200/12 , B01L2300/02 , B01L2300/0636 , B01L2300/0654 , B01L2300/0819 , G01N21/03 , G01N21/253 , G01N2021/0346 , G01N2201/0833
Abstract: The present invention provides a microfluidic device that can be used for fiber optic interrogation of multiple samples. The device comprises a substrate integrally comprising a plurality of optic fibers. A layer formed on a surface of the substrate defines at least one topological feature that communicates with at least one optic fiber for interrogation of a sample. The device preferably comprises a plurality of topological features that may include a patterned array of wells, channels or any combinations thereof. The plurality of optic fibers of a device of the invention are capable of interrogating thousands of samples simultaneously. These samples may include, without limitation, molecular, cellular, proteomic, genomic or gaseous materials or assays. The present invention also discloses a method for fabricating a microfluidic device. The invention also comprises a method for interrogating multiple samples in parallel via the microfluidic devices provided herein.
Abstract translation: 本发明提供了可用于多个样品的光纤询问的微流体装置。 该装置包括整体地包括多个光纤的基板。 形成在衬底的表面上的层限定了与至少一个光纤通信的至少一个拓扑特征，用于询问样品。 该装置优选地包括多个拓扑特征，其可以包括井的图案化阵列，通道或其任何组合。 本发明的装置的多个光纤能够同时询问数千个样品。 这些样品可以包括但不限于分子，细胞，蛋白质组学，基因组或气体材料或测定。 本发明还公开了一种用于制造微流体装置的方法。 本发明还包括通过本文提供的微流体装置并行询问多个样品的方法。
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公开(公告)号：DE3787380T2
公开(公告)日：1994-03-10
申请号：DE3787380
申请日：1987-06-26
Applicant: INCOM INC
Inventor： JESKEY RICHARD , PLOCHARCZYK JOHN
IPC: C03B37/027 , C03B37/028
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公开(公告)号：AT94158T
公开(公告)日：1993-09-15
申请号：AT87905325
申请日：1987-06-26
Applicant: INCOM INC
Inventor： JESKEY RICHARD V , PLOCHARCZYK JOHN R
IPC: C03B37/027 , C03B37/028
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公开(公告)号：AU3150684A
公开(公告)日：1984-12-18
申请号：AU3150684
申请日：1984-05-11
Applicant: INCOM INC
Inventor： JESKEY RICHARD V
IPC: G02B6/42 , C03B23/207 , C03B37/012 , G02B5/00 , G02B5/22 , G02B6/00 , G02B6/02 , G02B6/06 , C03B37/025 , G01J1/04 , G02B5/17 , G02B5/20
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公开(公告)号：EP3867687A1
公开(公告)日：2021-08-25
申请号：EP19873967.4
申请日：2019-10-10
Applicant: INCOM, INC.
Inventor： WELKER, David
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