公开(公告)号：WO2011068350A2

公开(公告)日：2011-06-09

申请号：PCT/KR2010/008543

申请日：2010-12-01

Applicant: KOREA BASIC SCIENCE INSTITUTE ,  LEE, Byoung Seob ,  WON, Mi Sook ,  KIM, Jong Pil ,  YOON, Jang Hee ,  BAE, Jong Seong ,  LEE, Hyo Sang ,  PARK, Jin Yong ,  PARK, Gyu Jun ,  LIM, Jung Hwan

Inventor： LEE, Byoung Seob ,  WON, Mi Sook ,  KIM, Jong Pil ,  YOON, Jang Hee ,  BAE, Jong Seong ,  LEE, Hyo Sang ,  PARK, Jin Yong ,  PARK, Gyu Jun ,  LIM, Jung Hwan

IPC: H05G1/00 ,  H05H1/24

CPC classification number: H05G2/003

Abstract: An apparatus for generating X-ray may include: a plasma chamber; a magnet unit for applying a magnetic field to the plasma chamber, the magnet unit configured to allow the control of the magnitude of the minimum magnetic field in the plasma chamber without change in structure; a microwave generator for applying microwaves to the plasma chamber; a reaction gas injected into the plasma chamber for generating X-ray through electron cyclotron resonance by the magnetic field and the microwaves; a variable guide for focusing the generated X-ray; and a variable extractor for outputting the focused X-ray from the plasma chamber.

Abstract translation: 用于产生X射线的设备可以包括：等离子体室; 磁体单元，用于向所述等离子体腔室施加磁场，所述磁体单元被配置为允许控制所述等离子体腔室中的最小磁场的大小而不改变结构; 微波发生器，用于向等离子体室施加微波; 注入到等离子体室中用于通过磁场和微波通过电子回旋共振产生X射线的反应气体; 用于聚焦所产生的X射线的可变指导; 以及用于从等离子体室输出聚焦X射线的可变提取器。

公开(公告)号：WO2010144811A1

公开(公告)日：2010-12-16

申请号：PCT/US2010/038328

申请日：2010-06-11

Applicant: FLORIDA STATE UNIVERSITY ,  KOREA BASIC SCIENCE INSTITUTE ,  PAINTER, Andrew ,  CHOI, Yeon Suk ,  KIM, Dong Lak ,  BAI, Hongyu

Inventor： PAINTER, Andrew ,  CHOI, Yeon Suk ,  KIM, Dong Lak ,  BAI, Hongyu

IPC: F25B9/00 ,  F25B19/00

CPC classification number: F25D19/006

Abstract: An apparatus for transferring cryogenic refrigeration includes a cryocooler interface, a housing, a working fluid, a heat exchanger, a flexible thermal link, and a remote cartridge cold head. The cryocooler interface is thermally connected to a cryocooler providing a source of refrigeration. The refrigeration is passed from the crycooler into the heat exchanger via the cryocooler interface. The remote cartridge cold head is attached to a remote location. Heat is drawn from the remote location through the remote cartridge cold head and into the heat exchanger via the working fluid within the flexible thermal link and housing. Within the heat exchanger, heat is transferred from the working fluid to the refrigeration source, such as a cryocooler; accordingly, the remote location is cooled.

Abstract translation: 用于转移低温制冷的设备包括低温冷却器接口，壳体，工作流体，热交换器，柔性热连接器和远程冷库冷头。 低温冷却器界面热连接到提供冷冻源的低温冷却器。 制冷从冷冻机通过低温冷却器接口进入热交换器。 远程墨盒冷头连接到远程位置。 热量从远程位置通过远程墨盒冷头抽出，并通过柔性热连接件和外壳内的工作流体进入热交换器。 在热交换器内，热量从工作流体传递到制冷源，例如低温冷却器; 因此，远程位置被冷却。

公开(公告)号：WO2009110655A1

公开(公告)日：2009-09-11

申请号：PCT/KR2008/002379

申请日：2008-04-25

Applicant: SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION ,  INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY ,  KOREA BASIC SCIENCE INSTITUTE ,  FOOD SCIENCE CO., LTD. ,  RYU, Do Hyun ,  HWANG, Geum Sook ,  KIM, Kun Hong ,  PARK, Jin Hyun ,  KIM, Hwa Jin

Inventor： RYU, Do Hyun ,  HWANG, Geum Sook ,  KIM, Kun Hong ,  PARK, Jin Hyun ,  KIM, Hwa Jin

IPC: C07C69/52

CPC classification number: C07C67/31 ,  C07B2200/09 ,  C07C67/343 ,  C07C69/73 ,  C07C69/732 ,  C07C69/738 ,  C07C255/57 ,  C07C311/19 ,  C07F7/1852

Abstract: Provided are β-substituted Morita-Baylis-Hillman (MBH) derivatives, pharmaceutically acceptable salts, hydrates, solvates and stereoisomers thereof. The derivatives may be prepared by preparing β-iodo-MBH esters from a variety of carbonyl compounds such as aldehydes and ketones, or imines in the presence of a Lewis acid as a basic backbone, and substituting iodide on a vinyl position with a variety of substituents. In addition, the β-substituted MBH derivatives have an excellent pharmaceutical effect in preventing and treating cancer.

Abstract translation: 提供的是取代的Morita-Baylis-Hillman（MBH）衍生物，其药学上可接受的盐，水合物，溶剂化物和立体异构体。 衍生物可以通过在路易斯酸作为碱性主链的存在下由各种羰基化合物如醛和酮或亚胺制备β-碘-MBH酯来制备，并且在乙烯基位置用各种各样的 取代。 此外，β取代的MBH衍生物在预防和治疗癌症中具有优异的药物作用。

公开(公告)号：WO2007018327A1

公开(公告)日：2007-02-15

申请号：PCT/KR2005/003037

申请日：2005-09-14

Applicant: KOREA BASIC SCIENCE INSTITUTE ,  AHN, Yeong Hee ,  KWON, Kyung-Hoon ,  YOO, Jong Shin

Inventor： AHN, Yeong Hee ,  KWON, Kyung-Hoon ,  YOO, Jong Shin

IPC: G01N33/68

CPC classification number: C07K14/4732

Abstract: The present invention relates to a method for analyzing modified polypeptide sequence and modified information thereof. More precisely, the invention relates to a method for identifying modified peptide in which fragment ion signals are obtained from target peptide precursor by using tandem mass spectrometry, candidate peptides and every possible peptide fragmentation patterns thereof are designed based on the mass data thereby, match scores corresponding to each fragmentation pattern of candidate peptides are given, and then by combining each matching scores derived from possible fragmentation patterns of a candidate peptide, modified target polypeptide is identified by tandem mass data based on the provided match score. The scoring method for modified polypeptide of the present invention can greatly contribute to increasing searching efficiency of modified peptides and reliability of the searching results by integrating all scored values obtained from different fragmentation patterns of a candidate peptide.

Abstract translation: 本发明涉及一种分析修饰多肽序列的方法及其修饰信息。 更准确地说，本发明涉及一种用于鉴定通过使用串联质谱法从靶肽前体获得片段离子信号的修饰肽的方法，并且基于质量数据设计候选肽和其每种可能的肽断裂模式，从而匹配得分 对应于候选肽的每个断裂模式，然后通过组合从候选肽的可能的断裂模式导出的每个匹配分数，基于所提供的匹配分数，通过串联质量数据鉴定修饰的目标多肽。 本发明的修饰多肽的评分方法可以通过整合从候选肽的不同片段化模式获得的所有得分值，大大有助于提高修饰肽的搜索效率和搜索结果的可靠性。

公开(公告)号：WO2009133981A1

公开(公告)日：2009-11-05

申请号：PCT/KR2008/002679

申请日：2008-05-14

Applicant: KOREA BASIC SCIENCE INSTITUTE ,  YOON, Jang Hee ,  WON, Mi Sook

Inventor： YOON, Jang Hee ,  WON, Mi Sook

IPC: G01N27/30

CPC classification number: G01N33/1893 ,  G01N27/308 ,  G01N33/1813

Abstract: Disclosed herein is an electrochemical measurement system for analyzing heavy metals in organic compound-containing samples, comprising: a lower plate; a flow channel plate; an upper plate; an organic compound-decomposing electrode and a heavy metal analysis electrode; and a flow changeover portion. The disclosed system can continuously perform a pretreatment process for organic compound decomposition and a process for heavy metal analysis, thus making it possible to achieve the selective analysis and separation of heavy metals in wastewater. Also, it can substitute for expensive spectrophotometric analysis equipment and makes it possible to monitor trace heavy metals on-line in situ. In addition, it may include a small-sized battery as a power source, such that it is easy to carry and use.

Abstract translation: 本文公开了一种用于分析含有机化合物的样品中的重金属的电化学测量系统，包括：下板; 流道板; 上板 有机化合物分解电极和重金属分析电极; 和流动切换部。 所公开的系统可以连续进行有机化合物分解的预处理过程和重金属分析过程，从而可以实现废水中重金属的选择性分析和分离。 此外，它可以替代昂贵的分光光度分析设备，并可以在线原位监测痕量重金属。 此外，它可以包括作为电源的小尺寸电池，使得其容易携带和使用。

公开(公告)号：WO2008002089A1

公开(公告)日：2008-01-03

申请号：PCT/KR2007/003150

申请日：2007-06-28

Applicant: KOREA BASIC SCIENCE INSTITUTE ,  YOO, Suk-Jae ,  LEE, Bong-Ju

Inventor： YOO, Suk-Jae ,  LEE, Bong-Ju

IPC: H01L21/3065

CPC classification number: H01J37/3266 ,  H01J37/32009 ,  H01J37/32623 ,  H01J2237/31

Abstract: The present invention relates to an apparatus for generating neutral particle beam with enhanced neutral particle flux. The apparatus of the present invention comprises a plasma discharging space inside which processing gases are converted into plasma ions through a plasma discharge, a metal plate which converts the plasma ions into neutral particles through collisions with the plasma ions, a plasma limiter which prevents the plasma ions and electrons from passing through and allows the neutral particles produced by collisions of the plasma ions with the metal plate to pass through, and a magnetron unit which applies magnetic field to the plasma discharging space, wherein the plasma discharging space is sandwiched between the metal plate and the plasma limiter, and the magnetron unit applies the magnetic field across the metal plate to the plasma discharging space to control plasma distribution. Preferably, the magnetron unit comprises a central pole and a side pole having a race track arrangement. The magnetic field applied across the metal plate increases density of the plasma ions near the metal plate. This improves the conversion efficiency of the plasma ions into the neutral particles to increase neutral particle flux.

Abstract translation: 本发明涉及一种产生具有增强的中性粒子通量的中性粒子束的装置。 本发明的装置包括等离子体放电空间，其中处理气体通过等离子体放电转换成等离子体离子;金属板，其通过与等离子体离子的碰撞将等离子体离子转换成中性粒子;等离子体限制器，其阻止等离子体 离子和电子通过，并且允许通过等离子体离子与金属板的碰撞产生的中性粒子通过;以及向等离子体放电空间施加磁场的磁控管单元，其中等离子体放电空间夹在金属 板和等离子体限制器，并且磁控管单元将金属板上的磁场施加到等离子体放电空间以控制等离子体分布。 优选地，磁控管单元包括具有轨道装置的中心极和侧极。 金属板上施加的磁场增加了金属板附近的等离子体离子的密度。 这提高了等离子体离子进入中性粒子的转化效率，以增加中性粒子通量。

公开(公告)号：WO2008002046A1

公开(公告)日：2008-01-03

申请号：PCT/KR2007/003070

申请日：2007-06-25

Applicant: KOREA BASIC SCIENCE INSTITUTE ,  YOO, Suk-Jae ,  LEE, Bong-Ju

Inventor： YOO, Suk-Jae ,  LEE, Bong-Ju

IPC: H01L21/203

CPC classification number: H01J37/3266 ,  H01J37/32357 ,  H01J37/32422 ,  H01L21/02631

Abstract: There is provided an apparatus for generating solid element neutral particle beam. The apparatus comprises a) a plasma discharging space inside which a plasma discharge takes places to produce plasma, b) a solid element coating layer positioned at side of the plasma discharging space to which a first bias voltage is applied to drive plasma ions to the solid element coating layer, c) a first magnetron unit that applies magnetic field across the solid element coating layer, and d) a metal plate positioned at top of the of the plasma discharging space to which a second bias voltage is applied to drive solid element cations to the metal plate. Preferably, the apparatus further comprises a second magnetron unit that applies magnetic field across the metal plate. Par¬ ticularly preferable is that each of the first and second magnetron units comprises a central pole and a side pole having a race track arrangement. The apparatus is useful for surface treatment.

Abstract translation: 提供了一种用于产生固体元素中性粒子束的装置。 该装置包括：a）等离子体放电空间，等离子体放电发生在其中以产生等离子体; b）位于等离子体放电空间侧面的固体元件涂层，施加第一偏置电压以驱动等离子体离子到固体 元件涂层，c）在固体元件涂层上施加磁场的第一磁控管单元，以及d）位于等离子体放电空间顶部的金属板，施加第二偏置电压以驱动固体元素阳离子 到金属板。 优选地，该装置还包括在金属板上施加磁场的第二磁控管单元。 特别优选的是，第一和第二磁控管单元中的每一个包括具有轨道装置的中心极和侧极。 该设备可用于表面处理。

公开(公告)号：WO2007126165A1

公开(公告)日：2007-11-08

申请号：PCT/KR2006/001613

申请日：2006-04-28

Applicant: KOREA BASIC SCIENCE INSTITUTE ,  KIM, Young-min ,  JEONG, Jong-man ,  KIM, Youn-joong ,  LEE, Jeong-yong

Inventor： KIM, Young-min ,  JEONG, Jong-man ,  KIM, Youn-joong ,  LEE, Jeong-yong

IPC: G01N27/12

CPC classification number: G01N23/04

Abstract: Disclosed is a method for manufacturing an ultra-thin carbon support film. The method provid es the ultra-thin carbon support film used as a specimen for high resolution transmission electron microscope (HRTEM) analysis for analyzing atom structures of nano-particle specimens. The ultra-thin carbon support film is fabricated such that a large- sized holy region is formed in the ultra-thin carbon support film, so that it is possible to obtain images of particles lying on the holy region through the HRTEM analysis while minimizing the size of the support film in the images. The ultra-thin carbon support film has a thinner thickness while maintaining structural and thermal stabilities, so the ultra-thin carbon support film is advantageously used for the HRTEM analysis of specimens.

Abstract translation: 公开了一种制造超薄碳载体膜的方法。 该方法提供了用于分析纳米颗粒样品原子结构的高分辨率透射电子显微镜（HRTEM）分析的超薄碳支撑膜。 制造超薄碳载体膜，使得在超薄碳载体膜中形成大尺寸的圣地区，使得可以通过HRTEM分析获得位于圣地区的颗粒的图像，同时最小化 图像中支持胶片的尺寸。 超薄碳载体膜具有更薄的厚度，同时保持结构和热稳定性，因此超薄碳载体膜有利地用于样品的HRTEM分析。

公开(公告)号：WO2007102706A1

公开(公告)日：2007-09-13

申请号：PCT/KR2007/001129

申请日：2007-03-07

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY ,  KOREA BASIC SCIENCE INSTITUTE ,  KONG, Hong Jin ,  LEE, Bong Ju

Inventor： KONG, Hong Jin ,  LEE, Bong Ju

IPC: G02B6/26

CPC classification number: H01S3/2383 ,  H01S3/10023 ,  H01S3/10076 ,  H01S3/1301 ,  H01S3/1307

Abstract: The object of this invention is to provide a phase stabilization device for stimulated brillouin scattering-phase conjugate mirrors and a light amplification apparatus using the phase stabilization device. A light amplification apparatus of the present invention includes a polarizer (70) for polarizing light beams reflected from a plurality of stimulated brillouin scattering-phase conjugate mirrors and causing the light beams to interfere with each other. A detector (80) acquires an interfering beam resulting from interference of the polarizer (70), and outputs the interfering beam. A phase controller (90) controls phase using the interfering beam acquired by the detector. Therefore, the apparatus of the present invention can stably lock the phase for a long period of time, and can be used in various industries and for scientific research in cases where a high repetition rate and high power are required.

Abstract translation: 本发明的目的是提供一种用于受激布里渊散射相位共轭反射镜的相位稳定装置和使用该相位稳定装置的光放大装置。 本发明的光放大装置包括用于偏振从多个受激布里渊散射相位共轭反射镜反射的光束并使光束彼此干涉的偏振器（70）。 检测器（80）获取由偏振器（70）的干涉产生的干涉光束，并输出干涉光束。 相位控制器（90）使用由检测器获取的干涉光束来控制相位。 因此，本发明的装置可以长期稳定地锁定相位，并且可以在需要高重复率和高功率的情况下用于各种行业和科学研究。

公开(公告)号：WO2013085181A1

公开(公告)日：2013-06-13

申请号：PCT/KR2012/009912

申请日：2012-11-22

Applicant: KOREA BASIC SCIENCE INSTITUTE

Inventor： CHOI, Yeon Suk ,  KIM, Dong Lak ,  KIM, Myung Su

IPC: H01F6/04

CPC classification number: H01F6/04 ,  F25D19/00

Abstract: A cooling system for superconductive magnets according to the present disclosure includes a vacuous container, a superconductive magnet forming a magnetic field, a superconductive magnet bobbin surrounding the superconductive magnet and made of thermally conductive material, a freezer for exchanging heat with the superconductive magnet bobbin to cool the superconductive magnet, a vibration-type heat pipe contacting the superconductive magnet bobbin to induce heat exchange with the freezer, and a radiation shield for blocking heat radiation introduced to the superconductive magnet. Therefore, it is possible to implement a stable cyrogenic cooling system, which may eliminate the generation of a temperature gradient between the freezer and the superconductive magnet so that the superconductive magnet may be efficiently cooled and may recover a superconducting status within a short time.

Abstract translation: 根据本公开的超导磁体的冷却系统包括真空容器，形成磁场的超导磁体，围绕超导磁体并由导热材料制成的超导磁体线圈，用于与超导磁体线轴交换热量的冷冻器 冷却超导磁体，与超导磁体线轴接触的振动型热管引起与冷冻机的热交换，以及用于阻挡引入超导磁体的热辐射的辐射屏蔽。 因此，可以实现稳定的循环冷却系统，其可以消除冷冻器和超导磁体之间的温度梯度的产生，使得超导磁体可以被有效地冷却并且可以在短时间内恢复超导状态。