Abstract:
Embodiments disclosed herein include a sensor device that monitors external activity and that includes functionality to detect tampering of the device itself. When monitoring for tampering, a power switch is disabled. Techniques include detecting relative movement of the sensor device, reporting tampering activity, and executing tamper detection responses. Responses can include tracking geographical movement and/or subsequent tampering activity to assist in recovery of a transported device. Responses can also include adjusting power consumption such as by modifying sensing functionality of the sensor device. Techniques include use of an accelerometer that can be positioned in the sensor device to detect relative movement. Once relative movement meets a predetermined threshold indicating device tampering, the sensor device transmits a notification of such tampering, via a network, or in response to a query from an authorized peer device.
Abstract:
A technology is described for a Photonic Integrated Circuit (PIC) radio frequency (RF) oscillator. The PIC RF oscillator can comprise an optical gain media coupled to a first mirror and configured to be coupled to the PIC. The PIC can comprise a first optical cavity located within the PIC, a tunable mirror to form a first optical path between the first mirror in the gain media and the first tunable mirror, and a frequency tunable intra-cavity dual tone resonator positioned within the first optical cavity to constrain the first optical cavity having a common optical path to produce tow primary laser tones with a tunable frequency spacing. A photo detector is optically coupled to the PIC and configured to mix the two primary laser tones to form an RF output signal with a frequency selected by the tunable frequency spacing of the two primary tones.
Abstract:
The present disclosure is drawn to loop-mediated isothermal amplification (LAMP) reaction assemblies including a substantially hygroscopic agent free LAMP reagent mixture in combination with a solid-phase reaction medium. The present disclosure also includes systems for a chromatic LAMP analysis including a substantially non-reactive solid phase reaction medium, and a non-interfering reagent mixture. The present disclosure also includes solid phase LAMP reaction mediums comprising a substrate, an adhesive layer disposed on the substrate, a reaction layer disposed on the adhesive layer, and a spreading layer disposed on the reaction layer. The present disclosure also includes methods of testing for a presence of a target nucleotide sequence including providing a biological sample, and dispensing the sample into a test environment having a solid phase reaction medium in combination with a LAMP reagent mixture and a pH sensitive dye.
Abstract:
The present disclosure is drawn to methods of preparing a saliva sample for loop-mediated isothermal amplification (LAMP) detection of a pathogen target. In some embodiments, such methods can include providing an amount of saliva from a test subject, and diluting the saliva in water to a degree that reduces a buffering capacity of the saliva while maintaining a sufficient concentration to allow for detection of the pathogen target.
Abstract:
A reservoir computer. In some embodiments, the reservoir computer includes a discrete element transmission line and a readout circuit. The discrete element transmission line may include a plurality of shunt-connected Josephson junctions (105) and a plurality of series- connected inductors (110) connected to the shunt-connected Josephson junctions. The readout circuit is connected to at least three nodes (117) of the discrete element transmission line.
Abstract:
According to an example, a method of analyzing an output of a sequencer is provided comprising identifying genetic targets, obtaining target signature snippets responsive thereto, each target signature snippet derived from a genetic sequence of the genetic targets, receiving portions of a test sequence output by a sequencer sequencing a sample in real time, determining, in real time or near-real time with the sequencer sequencing the sample, whether a target signature snippet of the target signature snippets is in at least one portion of the test sequence, determining, for each genetic target, a probability the genetic target is in the sample based on the determination of whether the target signature snippet is present in the at least one portion of the test sequence, and outputting an analysis of the sample indicating the respective probability that each genetic target is present in the sample.
Abstract:
In one aspect, a photonic device includes a substrate layer comprising magnesium fluoride and an optical guiding layer disposed on the substrate layer. The optical guide layer includes silicon dioxide. The substrate layer and the optical guide layer are transparent at an ultraviolet and visible wavelength range. In another aspect, a method includes oxidizing silicon to form a silicon dioxide layer, bonding the silicon dioxide layer to magnesium fluoride, removing the silicon and performing lithography and etching of the silicon dioxide to form a photonic device.
Abstract:
Optical sensing systems having improved vibration cancelation, and methods of achieving improved vibration cancelation. In one example, an optical sensing system (200) includes an optical sensor (210) configured to produce an unprocessed sensor output signal (215) representative of a response of the optical sensor to at least an optical signature of interest and a local vibration excitation, a reference sensor (220) configured to provide a reference signal responsive (225) to the local vibration excitation, and a controller (260), including an adaptive digital filter (230), coupled to the optical sensor and to the reference sensor, and configured to receive the reference signal and to adjust one or more coefficients of the adaptive digital filter to minimize coherence between a residual signal (255) and the reference signal, the residual signal being a difference between the sensor output signal and a filter output signal (235) from the adaptive digital filter.
Abstract:
An infrared bolometer. In one embodiment a waveguide configured to transmit infrared radiation is arranged to be adjacent a graphene sheet and configured so that evanescent waves from the waveguide overlap the graphene sheet. The graphene sheet has two contacts connected to an amplifier, and a power detector connected to the amplifier. Infrared electromagnetic power in the evanescent waves is absorbed in the graphene sheet, heating the graphene sheet. The power of Johnson noise generated at the contacts is proportional to the temperature of the graphene sheet. The Johnson noise is amplified and the power in the Johnson noise is used as a measure of the temperature of the graphene sheet, and of the amount of infrared power propagating in the waveguide.
Abstract:
A detector for detecting single photons of infrared radiation. A waveguide configured to transmit infrared radiation is arranged to be adjacent a graphene sheet and configured so that evanescent waves from the waveguide overlap the graphene sheet. An infrared photon absorbed by the graphene sheet from the evanescent waves heats the graphene sheet. The graphene sheet is coupled to the weak link of a Josephson junction, and a constant bias current is driven through the Josephson junction, so that an increase in the temperature of the graphene sheet results in a decrease in the critical current of the Josephson junction and a voltage pulse in the voltage across the Josephson junction. The voltage pulse is detected by the pulse detector.