公开(公告)号：WO2002076338A2

公开(公告)日：2002-10-03

申请号：PCT/US2002/008674

申请日：2002-03-21

Applicant: CALHOUN VISION ,  JETHMALANI, Jagdish, M. ,  CHANG, Shiao, H. ,  GRUBBS, Robert, H. ,  KORNFIELD, Julia, A. ,  SCHWARTZ, Daniel, M. ,  SANDSTEDT, Christian, A. ,  CHRIST, F., Richard

Inventor： JETHMALANI, Jagdish, M. ,  CHANG, Shiao, H. ,  GRUBBS, Robert, H. ,  KORNFIELD, Julia, A. ,  SCHWARTZ, Daniel, M. ,  SANDSTEDT, Christian, A. ,  CHRIST, F., Richard

IPC: A61F

CPC classification number: A61F2/16 ,  A61F2/1613 ,  A61F2/1616 ,  A61F2/1627 ,  A61F2/1635 ,  A61F2002/1699 ,  A61L27/14 ,  A61L27/50 ,  A61L2430/16 ,  B29D11/00009 ,  B29D11/00355 ,  B29D11/023 ,  G02C7/02 ,  G02C2202/14

Abstract: The present invention relates to a method for creating shaped implants, such as intraocular lenses in vivo , as well as the novel implants themselves. Utilizing the method of the invention, it is possible to create an implant in vivo and to adjust either the physical properties such as refractive index, viscosity, etc., mechanical properties such as modulus, tensile strength, tear, etc., or the shape of the implant by noninvasive means. For example, using the method of the patent it is possible to create an intraocular lens in vivo and then adjust the shape and power of the lens through no invasion means. The novel implants are also addressed in this application.

Abstract translation: 本发明（图1）涉及用于产生成形植入物的方法，例如体内的眼内透镜，以及新颖的植入物本身。 利用本发明的方法，可以在体内产生植入物，并且可以调节诸如折射率，粘度等的物理性质，模量，拉伸强度，撕裂等的机械性能或形状 的植入物通过无创手段。 例如，使用该专利的方法，可以在体内产生眼内透镜，然后通过无侵入手段来调整透镜的形状和功率。 本申请中还提到了新颖的植入物。

公开(公告)号：WO0041650B1

公开(公告)日：2000-10-19

申请号：PCT/US9923728

申请日：1999-10-13

Applicant: CALIFORNIA INST OF TECHN ,  UNIV CALIFORNIA SAN FRANCISCO ,  JETHMALANI JAGDISH M ,  GRUBBS ROBERT H ,  SANDSTEDT CHRISTIAN A ,  KORNFIELD JULIA A ,  SCHWARTZ DANIEL M

Inventor： JETHMALANI JAGDISH M ,  GRUBBS ROBERT H ,  SANDSTEDT CHRISTIAN A ,  KORNFIELD JULIA A ,  SCHWARTZ DANIEL M

IPC: G02C7/04 ,  A61F2/16 ,  A61L27/00 ,  A61L27/18 ,  G02B1/04 ,  G02B3/14 ,  G02C7/06

CPC classification number: G02B3/00 ,  A61F2/16 ,  A61F2/1627 ,  A61F2/1635 ,  A61L27/18 ,  A61L2430/16 ,  G02B1/043 ,  G02C7/04 ,  G02C2202/14 ,  C08L83/04

Abstract: The present invention relates to lenses that are capable of post-fabrication power modifications. In general, the inventive lenses comprise (i) a first polymer matrix and (ii) a refraction modulating composition that is capable of stimulus-induced polymerization dispersed therein. When at least a portion of the lens is exposed to an appropriate stimulus, the refraction modulating composition forms a second polymer matrix. The amount and location of the second polymer matrix may modify a lens characteristic such as lens power by changing its refractive index and/or by altering its shape. The inventive lenses have a number of applications in the electronics and medical fields as data storage means and as medical lenses, particularly intraocular lenses, respectively.

Abstract translation: 本发明涉及能够进行制造后功率修改的透镜。 通常，本发明的镜片包含（i）第一聚合物基质和（ii）能够刺激分散于其中的刺激聚合的折射调节组合物。 当透镜的至少一部分暴露于适当的刺激时，折射调制组合物形成第二聚合物基质。 第二聚合物基质的量和位置可以通过改变其折射率和/或通过改变其形状来改变透镜特性，例如透镜光焦度。 本发明的透镜在电子和医疗领域中作为数据存储装置和作为医用透镜，尤其是眼内透镜分别具有许多应用。

公开(公告)号：US2481952A

公开(公告)日：1949-09-13

申请号：US59829045

申请日：1945-06-08

Applicant: SCHWARTZ DANIEL M ,  MCLEAN WILLIAM B

Inventor： SCHWARTZ DANIEL M ,  MCLEAN WILLIAM B

IPC: B23K9/28

CPC classification number: B23K9/282 ,  Y10T24/44872

公开(公告)号：US2564376A

公开(公告)日：1951-08-14

申请号：US62926645

申请日：1945-11-17

Applicant: SCHWARTZ DANIEL M ,  HACKETT THEODORE N

Inventor： SCHWARTZ DANIEL M ,  HACKETT THEODORE N

IPC: G01B5/20

CPC classification number: G01B5/20