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    Inline concentration measurement device
    21.
    发明授权
    Inline concentration measurement device 有权

    公开(公告)号：US10222323B2

    公开(公告)日：2019-03-05

    申请号：US15321398

    申请日：2015-07-23

    Applicant: TOKUSHIMA UNIVERSITY ,  FUJIKIN INCORPORATED

    Inventor： Yoshihiro Deguchi ,  Masaaki Nagase ,  Nobukazu Ikeda ,  Michio Yamaji ,  Tadayuki Yakushijin

    IPC: G01N21/27 ,  G01N21/05 ,  G01N21/15

    Abstract: An inline concentration measurement device comprises: a measurement cell main body with a gas flow path formed; a light incident part with a window member connected to the main body; and a light receiving part with a window member connected to the main body, wherein the gas flow path includes a gas flow path for an optical path extending straight between the window members of the light incident part and the light receiving part, a first communication part making a gas inlet formed in the main body communicate with the gas flow path part for the optical path, and a second communication part making a gas outlet formed in the main body communicate with the gas flow path part for the optical path, and the first communication part obliquely extends from the gas inlet towards the window member of the light incident part.

    NOVEL HIGH FUNCTIONAL ENZYME HAVING MODIFIED SUBSTRATE SPECIFICITY OF HUMAN ß-HEXOSAMINIDASE B AND EXHIBITING PROTEASE RESISTANCE
    23.
    发明申请
    NOVEL HIGH FUNCTIONAL ENZYME HAVING MODIFIED SUBSTRATE SPECIFICITY OF HUMAN ß-HEXOSAMINIDASE B AND EXHIBITING PROTEASE RESISTANCE 审中-公开
    具有人ß-HEXOSAMINIDASE B改性基质特性的新型高功能酶和抗菌素抗性

    公开(公告)号：US20160137994A1

    公开(公告)日：2016-05-19

    申请号：US14436833

    申请日：2013-10-17

    Applicant: TOKUSHIMA UNIVERSITY ,  MEIJI PHARMACEUTICAL UNIVERSITY

    Inventor： Koji ITO ,  Hitoshi SAKURABA ,  Daisuke TSUJI

    IPC: C12N9/24 ,  A61K38/47

    CPC classification number: C12N9/2402 ,  A61K38/00 ,  A61K38/47 ,  C12Y302/01052

    Abstract: Provided is a modified β-subunit of human β-hexosaminidase which has the activity derived from the α-subunit of wild-type human β-hexosaminidase and has the resistance to protease. A protein comprising an amino acid sequence having substitutions of the 312th to the 318th amino acids with glycine, serine, glutamic acid, proline, serine, glycine and threonine in order, respectively, in an amino acid sequence of a β-subunit of wild-type human β-hexosaminidase.

    Abstract translation: 提供了具有衍生自野生型人类 - 半胱胺糖苷酶的α-亚单位的活性的人类 - 半胱胺酶的修饰和亚基，并具有对蛋白酶的抗性。 包含具有312至318位氨基酸的氨基酸序列的氨基酸序列的氨基酸序列分别与甘氨酸，丝氨酸，谷氨酸，脯氨酸，丝氨酸，甘氨酸和苏氨酸的氨基酸序列分别在野生型 型人类和半乳糖胺酶。

    Raw Material Fluid Density Detector
    24.
    发明申请
    Raw Material Fluid Density Detector 有权
    原料流体密度检测器

    公开(公告)号：US20160061704A1

    公开(公告)日：2016-03-03

    申请号：US14888841

    申请日：2014-04-30

    Applicant: TOKUSHIMA UNIVERSITY ,  FUJIKIN INCORPORATED

    Inventor： Yoshihiro DEGUCHI ,  Masaaki NAGASE ,  Ryousuke DOHI ,  Nobukazu IKEDA ,  Kouji NISHINO ,  Michio YAMAJI ,  Tadayuki YAKUSHIJIN

    IPC: G01N9/00 ,  G01N21/59 ,  G01N21/85

    CPC classification number: G01N9/00 ,  G01N9/24 ,  G01N21/05 ,  G01N21/33 ,  G01N21/59 ,  G01N21/85 ,  G01N2201/08

    Abstract: This invention is related to an optical-analysis-type raw material fluid density detector including a detector main body and a light oscillation unit and a light detection unit that are provided on the upper surface or the under surface of the detector main body, in which the detector main body has at least one recess formed in the upper surface and the under surface, a fluid flow path connecting a fluid inlet of the detector main body to the recess, a fluid flow path connecting the recesses to each other, and a fluid flow path connecting the recess to a fluid outlet of the detector main body; the light oscillation unit is disposed in the recess that is closest to the inlet; and light detection units are disposed in the remaining recesses.

    Abstract translation: 本发明涉及一种光学分析型原料流体密度检测器，其包括设在检测器主体的上表面或下表面上的检测器主体和光振荡单元以及光检测单元，其中 检测器主体具有形成在上表面和下表面中的至少一个凹部，将检测器主体的流体入口连接到凹部的流体流动路径，将凹部彼此连接的流体流路，以及流体 将所述凹部连接到所述检测器主体的流体出口的流路; 光振动单元设置在最靠近入口的凹部中; 并且光检测单元设置在剩余的凹部中。

    STOCK SOLUTION CONCENTRATING DEVICE, STOCK SOLUTION TREATMENT DEVICE, AND CIRCULATION-TYPE TREATMENT DEVICE
    25.
    发明申请
    STOCK SOLUTION CONCENTRATING DEVICE, STOCK SOLUTION TREATMENT DEVICE, AND CIRCULATION-TYPE TREATMENT DEVICE 审中-公开
    集中解决方案集中装置，储备解决方案处理装置和循环型处理装置

    公开(公告)号：US20160022895A1

    公开(公告)日：2016-01-28

    申请号：US14761226

    申请日：2014-01-14

    Applicant: TOKUSHIMA UNIVERSITY ,  Takatori Corporation

    Inventor： Toshiya OKAHISA ,  Yohsuke KINOUCHI ,  Tadahiko NAKAGAWA ,  Satoru YAMAJI ,  Zenji TANAKA

    IPC: A61M1/34 ,  B01D69/08

    CPC classification number: A61M1/3486 ,  A61M1/0281 ,  A61M1/3479 ,  A61M1/3482 ,  A61M2202/0401 ,  A61M2202/0415 ,  A61M2202/0492 ,  B01D63/02 ,  B01D65/08 ,  B01D69/08

    Abstract: Provided are a stock solution concentrating device, a stock solution treatment device and a circulation-type treatment device that can prevent the deposition of cells and the like on a filtration member and that can continuously filter and concentrate a stock solution such as pleural and ascitic fluid or blood plasma. The stock solution concentrating device concentrates a stock solution such as pleural and ascitic fluid or blood plasma to form a concentrated solution, and is equipped with: a filter (10) having a filtration member that filters the stock solution; a concentrator (20) to which the filtrate which has been filtered is supplied, and which concentrates the filtrate to form a concentrated solution; and a stock solution supply unit that supplies the stock solution to the filter (10). The stock solution supply unit has a supply amount adjustment function for adjusting the amount of the stock solution supplied to the filter.

    Abstract translation: 提供了能够防止细胞等沉积在过滤构件上的储液溶液浓缩装置，储备溶液处理装置和循环型处理装置，并且可以连续地过滤和浓缩诸如胸膜和腹水的储备溶液 或血浆。 储液集中装置将诸如胸膜和腹水或血浆之类的储液集中以形成浓缩溶液，并配备有：过滤器（10），其具有用于过滤储液的过滤构件; 浓缩器（20），向其中提供已经过滤的滤液，并浓缩滤液以形成浓缩溶液; 以及将储备溶液供给到过滤器（10）的储液供给单元。 储液供应单元具有用于调节供给到过滤器的储液的量的供给量调节功能。

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