형광염색과 이미지 분석을 통해 정량적 또는 3차원적으로표현할 수 있는 피부 각질 박리량의 평가법
    21.
    发明公开
    형광염색과 이미지 분석을 통해 정량적 또는 3차원적으로표현할 수 있는 피부 각질 박리량의 평가법 有权
    使用荧光染色和图像分析对人造棱镜进行定量分析或三维显示的量测量方法

    公开(公告)号:KR1020080091901A

    公开(公告)日:2008-10-15

    申请号:KR1020070034924

    申请日:2007-04-10

    Abstract: A method for measuring the amount of human stratum corneum exfoliation is provided to digitize the stratum corneum exfoliation amount using an image analysis program by improving a conventional technique of evaluating the stratum corneum exfoliation amount visually through fluorescence staining, thereby verifying the stratum corneum amount objectively. A method for measuring the amount of human stratum corneum exfoliation comprises the steps of: (a) coating a fluorescent staining sample such as Dansyl chloride and dihydroxyacetone on a stratum corneum of skin surface for fluorescence-staining; (b) coating a sample for exfoliation such as glycolic acid, lactic acid, malic acid, citric acid, tartaric acid, salicylic acid and papain enzyme on the fluorescent-stained stratum corneum for 4-14 days to perform exfoliation; (c) fluorescence-photographing the exfoliated stratum corneum to obtain a fluorescent image; and (d) setting up an analysis area of the fluorescent image and digitizing fluorescence strength of the analysis by using an image analysis program. Further, the step (a) of coating a fluorescent staining sample is performed for 6 hrs.

    Abstract translation: 提供了用于测量人角质层脱落量的方法,通过改进通过荧光染色目视评估角质层剥离量的常规技术,通过图像分析程序对角质层去角质量进行数字化,从而客观地验证角质层数量。 用于测量人角质层剥离量的方法包括以下步骤:(a)将荧光染色样品如丹酰氯和二羟基丙酮涂覆在皮肤表面的角质层上用于荧光染色; (b)在荧光染色的角质层上涂覆乙醇酸,乳酸,苹果酸,柠檬酸,酒石酸,水杨酸和木瓜蛋白酶等剥离性样品4-14天,进行剥离; (c)荧光拍摄剥离的角质层以获得荧光图像; 和(d)通过使用图像分析程序设置荧光图像的分析区域和数字化分析的荧光强度。 此外,涂布荧光染色样品的步骤(a)进行6小时。

    저점도상에서 난용성 물질을 안정하게 함유하는 시트형화장료
    22.
    发明公开
    저점도상에서 난용성 물질을 안정하게 함유하는 시트형화장료 无效
    低粘度水平状态下含有不溶性材料的薄片材料的化妆品

    公开(公告)号:KR1020080038812A

    公开(公告)日:2008-05-07

    申请号:KR1020060106237

    申请日:2006-10-31

    Abstract: A sheet-type cosmetic composition is provided to increase the effect of an insoluble material to skin by improving dispersion property of the insoluble material which is unable to be stabilized in a conventional low viscous formulation and immersing the insoluble material into a sheet. A sheet-type cosmetic composition is characterized in that it includes a sheet where a low-viscous nano-emulsion containing a liposomed insoluble material is immersed, wherein the insoluble material is at least one selected from the group consisting of retinol, a retinol derivative, tocopherol, tocopheryl acetate, tocopheryl linoleate, tocopheryl nicotinate, linoleic acid, coenzyme Q-10, resveratrol, a plant extract essential oil, ursolic acid, oleanolic acid, oil-soluble licorice root, and lipoic acid. Further, the 1 to 10 wt.% of insoluble liposome is comprised based on the 100 wt.% of cosmetic composition, and the low-viscous of the emulsion is 300 to 3000 CPS.

    Abstract translation: 提供片状化妆品组合物,通过改善常规低粘度制剂中不能稳定的不溶性材料的分散性能并将不溶性材料浸入片材中来增加不溶物质对皮肤的影响。 片状化妆品组合物的特征在于,其包含浸渍含有脂质体不溶性物质的低粘度纳米乳液的片材,其中,所述不溶性物质为选自视黄醇,视黄醇衍生物, 生育酚,生育酚乙酸酯,生育酚亚油酸酯,生育酚烟酸酯,亚油酸,辅酶Q-10,白藜芦醇,植物提取物精油,熊果酸,齐墩果酸,油溶性甘草根和硫辛酸。 此外,基于100重量%的化妆品组合物包含1至10重量%的不溶性脂质体,并且乳液的低粘度为300至3000CPS。

    Musk를 함유하는 피부건조 개선용 피부외용제 조성물
    24.
    发明公开
    Musk를 함유하는 피부건조 개선용 피부외용제 조성물 有权
    用于改善包含皮肤的皮肤干燥的外用组合物

    公开(公告)号:KR1020040071963A

    公开(公告)日:2004-08-16

    申请号:KR1020030007885

    申请日:2003-02-07

    CPC classification number: A61K8/981 A61K2800/75 A61Q19/00 Y10S514/857

    Abstract: PURPOSE: A composition containing musk having effects of strengthening the formation and maintenance of a natural moisturizing factor present in the stratum corneum of the skin and naturally increasing synthesis of lipid between cells is provided. It can be used as a therapeutic agent for preventing skin diseases such as atopic contact dermatitis as well as xeroderma or improving its symptoms. CONSTITUTION: The composition for external for improving the drying of the skin is characterized in that it contains 0.0001 to 20% by weight of musk as an effective ingredient, based on the total weight of the composition. The musk is musk 781 or musk T. The improvement in drying of the skin contains inducing the cell growth of keratinocyte, recovering a skin barrier, promoting the expression of filaggrin, activating PPAR(Peroxisome Proliferator Activated Receptor)-α, increasing biosynthesis of ceramide, improving skin moisturization, preventing atopic, contact dermatitis or improving its symptoms.

    Abstract translation: 目的:提供一种含有麝香的组合物,其具有加强皮肤角质层中天然保湿因子的形成和维持的作用,并且天然增加细胞之间的脂质合成。 它可以用作预防皮肤疾病如特应性接触性皮炎以及干性皮炎或改善其症状的治疗剂。 构成:用于改善皮肤干燥的外用组合物的特征在于,基于组合物的总重量,其含有0.0001至20重量%的麝香作为有效成分。 麝香是麝香781或麝香T.皮肤干燥的改善包括诱导角质形成细胞的细胞生长,恢复皮肤屏障,促进丝聚蛋白的表达,激活PPAR(过氧化物酶体增殖物激活受体)-α,增加神经酰胺的生物合成 改善皮肤保湿,预防特应性,接触性皮炎或改善其症状。

    사삼 추출물을 함유한 피부외용제 조성물
    25.
    发明公开
    사삼 추출물을 함유한 피부외용제 조성물 无效
    组合物外用于含有亚硝酸盐提取物的皮肤

    公开(公告)号:KR1020040058848A

    公开(公告)日:2004-07-05

    申请号:KR1020020085361

    申请日:2002-12-27

    Abstract: PURPOSE: Provided is a composition of external application to the skin containing extract of Adenophorea radix, thereby preventing dryness of the skin, improving moisture retaining property of the skin, and preventing and treating atopic dermatitis and skin inflammation. CONSTITUTION: A composition of external application to the skin is characterized by containing, as an active ingredient, 0.0001-60 wt.% of extract of Adenophorea radix. The composition moisturizes the skin, improves atopic dermatitis or skin inflammation, facilitates the differentiation of keratinocyte and expression of filaggrin, promotes the generation of ceramide, and activates PPAR-alpha.

    Abstract translation: 目的:提供外用于含有Adenophorea根的提取物的皮肤的组合物,从而防止皮肤干燥,改善皮肤的保湿性,以及预防和治疗特应性皮炎和皮肤炎症。 构成:外用于皮肤的组合物的特征在于含有0.0001-60重量%的Adenophorea根的提取物作为活性成分。 组合物润湿皮肤,改善特应性皮炎或皮肤炎症,促进角质形成细胞的分化和丝聚蛋白的表达,促进神经酰胺的产生,并激活PPAR-α。

    피부 번들거림 평가법
    27.
    发明授权

    公开(公告)号:KR101856976B1

    公开(公告)日:2018-05-15

    申请号:KR1020110125746

    申请日:2011-11-29

    Abstract: 본발명은피부표면반사광을측정하여제형에의한피부번들거림평가방법에관한것으로서, 보다구체적으로는제형시료를상기피부에도포하는단계; 상기도포된피부의표면반사광이미지를촬영하는단계; 상기이미지로부터광도를분석하는단계; 상기분석결과에서광량영역(intensity range)에서의광량합(intensity sum)을구하는단계; 및상기광량합을통해제형시료에의한피부번들거림(gloss) 정도를판정하는단계;를포함하는제형에의한피부번들거림평가방법에관한것으로, 서로다른제형들의피부번들거림에미치는영향을간소화된절차에의해육안으로보이는결과와가깝게객관적으로비교할수 있는제형간 비교에최적화된번들거림평가방법을제공할수 있다.

    피부 탄력 유지 및 개선 효과의 측정 방법
    28.
    发明授权
    피부 탄력 유지 및 개선 효과의 측정 방법 有权
    如何保持和改善皮肤弹性

    公开(公告)号:KR101790163B1

    公开(公告)日:2017-10-26

    申请号:KR1020110046586

    申请日:2011-05-18

    Abstract: 본발명은피부의탄력정도및 제품사용에의한피부주름효능을평가할수 있는방법에관한것으로서, 보다구체적으로는, 눈가피부에인위적으로주름을유발한후 원상태로돌아오는회복력을측정함으로써피부탄력정도를간접적으로평가할수 있는방법에관한것이다.

    Abstract translation: 本发明涉及一种能够评估由弹性皱纹效果和产品的对皮肤的程度,并且更具体地,通过测量弹性皮肤弹性程度而使人工的皱纹在眼睛周围的皮肤之后返回到原始状态的方法 间接评估系统性能的方法。

    피부 구조 측정 장치
    30.
    发明授权
    피부 구조 측정 장치 有权
    皮肤结构测量装置

    公开(公告)号:KR101710152B1

    公开(公告)日:2017-02-28

    申请号:KR1020100070850

    申请日:2010-07-22

    Abstract: 피부구조측정장치는, 측정대상피부에대해서로상이한방향에배열되며, 피부에순차적으로광을조사하도록구성된복수개의광원; 및피부를촬영하여상기복수개의광원각각에대응되는복수개의이미지를생성하는촬영부를포함할수 있다. 상기피부구조측정장치를이용하면, 피부에존재하는주름이나모공등과같은미세구조에대응되는노말맵을생성하고, 생성된노말맵을이미지로표시할수 있다. 이와같이생성된이미지를통하여특정화장품제품사용전후의피부구조개선효과등을알기쉽게가시적으로확인할수 있다.

    Abstract translation: 该皮肤构造测量装置具有:多个光源,其相对于测量对象皮肤以不同的方向排列,构成为依次照射光; 拍摄单元,用于拍摄皮肤并生成对应于多个光源的多个图像。 使用该皮肤构造测量装置,能够生成与存在于皮肤中的褶皱,毛孔等微细构造对应的法线图,能够将生成的法线图作为图像进行显示。 通过这样产生的图像,可以在视觉上确认在使用特定化妆品之前和之后改善皮肤结构的效果。

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