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公开(公告)号：KR1020080110943A
公开(公告)日：2008-12-22
申请号：KR1020050102895
申请日：2005-10-31
Applicant: (주)아모레퍼시픽
IPC: A61K31/335 , A61P19/02 , A61K8/49
Abstract: A composition for promoting the generation of hyaluronic acid containing Musk T is provided to realize the prevention and treatment of the degenerative arthritis. A composition for promoting the generation of hyaluronic acid contains Musk T with the concentration of 1.0 ~ 10 mug/ml as an active ingredient. The composition is for the oral or external use. The composition for treating degenerative arthritis contains a composition for promoting the generation of hyaluronic acid. A skin anti-aging composition contains a composition for promoting the generation of hyaluronic acid.
Abstract translation: 提供了用于促进含有Musk T的透明质酸的产生的组合物，以实现对退行性关节炎的预防和治疗。 用于促进透明质酸产生的组合物含有浓度为1.0〜10ug / ml的Musk T作为活性成分。 组合物用于口服或外用。 用于治疗退行性关节炎的组合物含有促进透明质酸产生的组合物。 皮肤抗衰老组合物含有促进透明质酸产生的组合物。
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公开(公告)号：KR100867596B1
公开(公告)日：2008-11-10
申请号：KR1020070034924
申请日：2007-04-10
Applicant: (주)아모레퍼시픽
IPC: G01N33/48 , G01N33/533
Abstract: 본 발명은 피부 각질 박리량을 정량할 수 있는 평가법으로서, 기존의 형광염색을 통해 육안적으로 각질 박리량을 평가하는 부분을 개선하여 이미지 분석 프로그램을 이용함으로써 각질박리량을 수치화하고, 객관적으로 각질 박리량을 검증할 수 있는 방법에 관한 것이다. 보다 상세하게는 피부 표면의 각질층을 형광염색시약으로 염색한 다음, 형광염색된 피부 표면에 각질 박리용 시료를 도포한 후 사진을 촬영하여 형광이미지를 얻음으로써 추적 관찰을 실시하고, 촬영한 사진의 형광이미지는 이미지 분석 프로그램을 이용함으로써 형광강도를 수치화하고, 형광이미지를 이용하여 3차원 이미지화 할 수 있다. 이를 통해 기존의 육안 판정에 의존하던 각질 박리 평가를 수치적으로 객관화 할 수 있으며, 3차원 이미지 변환을 통해 각질 박리 효과를 가시화 할 수 있다.
각질 박리, 형광염색, 댄실 클로라이드(Dansyl chloride), 디히드록시아세톤(Dihydroxyacetone), 이미지 분석, 형광강도, 흑백 전환-
公开(公告)号：KR1020080091901A
公开(公告)日：2008-10-15
申请号：KR1020070034924
申请日：2007-04-10
Applicant: (주)아모레퍼시픽
IPC: G01N33/48 , G01N33/533
Abstract: A method for measuring the amount of human stratum corneum exfoliation is provided to digitize the stratum corneum exfoliation amount using an image analysis program by improving a conventional technique of evaluating the stratum corneum exfoliation amount visually through fluorescence staining, thereby verifying the stratum corneum amount objectively. A method for measuring the amount of human stratum corneum exfoliation comprises the steps of: (a) coating a fluorescent staining sample such as Dansyl chloride and dihydroxyacetone on a stratum corneum of skin surface for fluorescence-staining; (b) coating a sample for exfoliation such as glycolic acid, lactic acid, malic acid, citric acid, tartaric acid, salicylic acid and papain enzyme on the fluorescent-stained stratum corneum for 4-14 days to perform exfoliation; (c) fluorescence-photographing the exfoliated stratum corneum to obtain a fluorescent image; and (d) setting up an analysis area of the fluorescent image and digitizing fluorescence strength of the analysis by using an image analysis program. Further, the step (a) of coating a fluorescent staining sample is performed for 6 hrs.
Abstract translation: 提供了用于测量人角质层脱落量的方法，通过改进通过荧光染色目视评估角质层剥离量的常规技术，通过图像分析程序对角质层去角质量进行数字化，从而客观地验证角质层数量。 用于测量人角质层剥离量的方法包括以下步骤：（a）将荧光染色样品如丹酰氯和二羟基丙酮涂覆在皮肤表面的角质层上用于荧光染色; （b）在荧光染色的角质层上涂覆乙醇酸，乳酸，苹果酸，柠檬酸，酒石酸，水杨酸和木瓜蛋白酶等剥离性样品4-14天，进行剥离; （c）荧光拍摄剥离的角质层以获得荧光图像; 和（d）通过使用图像分析程序设置荧光图像的分析区域和数字化分析的荧光强度。 此外，涂布荧光染色样品的步骤（a）进行6小时。
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公开(公告)号：KR1020080038812A
公开(公告)日：2008-05-07
申请号：KR1020060106237
申请日：2006-10-31
Applicant: (주)아모레퍼시픽
Abstract: A sheet-type cosmetic composition is provided to increase the effect of an insoluble material to skin by improving dispersion property of the insoluble material which is unable to be stabilized in a conventional low viscous formulation and immersing the insoluble material into a sheet. A sheet-type cosmetic composition is characterized in that it includes a sheet where a low-viscous nano-emulsion containing a liposomed insoluble material is immersed, wherein the insoluble material is at least one selected from the group consisting of retinol, a retinol derivative, tocopherol, tocopheryl acetate, tocopheryl linoleate, tocopheryl nicotinate, linoleic acid, coenzyme Q-10, resveratrol, a plant extract essential oil, ursolic acid, oleanolic acid, oil-soluble licorice root, and lipoic acid. Further, the 1 to 10 wt.% of insoluble liposome is comprised based on the 100 wt.% of cosmetic composition, and the low-viscous of the emulsion is 300 to 3000 CPS.
Abstract translation: 提供片状化妆品组合物，通过改善常规低粘度制剂中不能稳定的不溶性材料的分散性能并将不溶性材料浸入片材中来增加不溶物质对皮肤的影响。 片状化妆品组合物的特征在于，其包含浸渍含有脂质体不溶性物质的低粘度纳米乳液的片材，其中，所述不溶性物质为选自视黄醇，视黄醇衍生物， 生育酚，生育酚乙酸酯，生育酚亚油酸酯，生育酚烟酸酯，亚油酸，辅酶Q-10，白藜芦醇，植物提取物精油，熊果酸，齐墩果酸，油溶性甘草根和硫辛酸。 此外，基于100重量％的化妆品组合物包含1至10重量％的不溶性脂质体，并且乳液的低粘度为300至3000CPS。
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公开(公告)号：KR1020050099406A
公开(公告)日：2005-10-13
申请号：KR1020040024704
申请日：2004-04-10
Applicant: (주)아모레퍼시픽
IPC: C07C31/24
CPC classification number: C09K19/06 , A61K8/39 , A61Q19/00 , C07C67/08 , C07C69/708 , C11D3/2093 , C11D17/0026
Abstract: 본 발명은 피부에 적용되었을 때 각질층의 수분 유지 능력을 향상시키며, 특히 건조환경에서도 높은 보습력을 보이는, 하기 화학식 1로 표시되는 펜타에리스리톨 유도체 및 이의 제조방법, 그리고 이를 포함하는 액정베이스에 관한 것이다.
(상기 식에서, R은 서로 동일하거나 다른 수소 또는 히드록시기를 포함하거나 포함하지 않는 탄소수 1 내지 24개의 포화, 불포화 및 직쇄, 분지쇄를 포함하는 알킬기이고; m은 0 내지 10, n은 1 내지 10의 서로 동일하거나 다른 정수이다.)-
Patent Agency Ranking
公开(公告)号：KR1020040071963A
公开(公告)日：2004-08-16
申请号：KR1020030007885
申请日：2003-02-07
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/981 , A61K2800/75 , A61Q19/00 , Y10S514/857
Abstract: PURPOSE: A composition containing musk having effects of strengthening the formation and maintenance of a natural moisturizing factor present in the stratum corneum of the skin and naturally increasing synthesis of lipid between cells is provided. It can be used as a therapeutic agent for preventing skin diseases such as atopic contact dermatitis as well as xeroderma or improving its symptoms. CONSTITUTION: The composition for external for improving the drying of the skin is characterized in that it contains 0.0001 to 20% by weight of musk as an effective ingredient, based on the total weight of the composition. The musk is musk 781 or musk T. The improvement in drying of the skin contains inducing the cell growth of keratinocyte, recovering a skin barrier, promoting the expression of filaggrin, activating PPAR(Peroxisome Proliferator Activated Receptor)-α, increasing biosynthesis of ceramide, improving skin moisturization, preventing atopic, contact dermatitis or improving its symptoms.
Abstract translation: 目的：提供一种含有麝香的组合物，其具有加强皮肤角质层中天然保湿因子的形成和维持的作用，并且天然增加细胞之间的脂质合成。 它可以用作预防皮肤疾病如特应性接触性皮炎以及干性皮炎或改善其症状的治疗剂。 构成：用于改善皮肤干燥的外用组合物的特征在于，基于组合物的总重量，其含有0.0001至20重量％的麝香作为有效成分。 麝香是麝香781或麝香T.皮肤干燥的改善包括诱导角质形成细胞的细胞生长，恢复皮肤屏障，促进丝聚蛋白的表达，激活PPAR（过氧化物酶体增殖物激活受体）-α，增加神经酰胺的生物合成 改善皮肤保湿，预防特应性，接触性皮炎或改善其症状。
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公开(公告)号：KR1020040058848A
公开(公告)日：2004-07-05
申请号：KR1020020085361
申请日：2002-12-27
Applicant: (주)아모레퍼시픽
CPC classification number: A61K36/342 , A61K9/0014 , A61K2236/331 , A61K2236/51 , Y10S514/857
Abstract: PURPOSE: Provided is a composition of external application to the skin containing extract of Adenophorea radix, thereby preventing dryness of the skin, improving moisture retaining property of the skin, and preventing and treating atopic dermatitis and skin inflammation. CONSTITUTION: A composition of external application to the skin is characterized by containing, as an active ingredient, 0.0001-60 wt.% of extract of Adenophorea radix. The composition moisturizes the skin, improves atopic dermatitis or skin inflammation, facilitates the differentiation of keratinocyte and expression of filaggrin, promotes the generation of ceramide, and activates PPAR-alpha.
Abstract translation: 目的：提供外用于含有Adenophorea根的提取物的皮肤的组合物，从而防止皮肤干燥，改善皮肤的保湿性，以及预防和治疗特应性皮炎和皮肤炎症。 构成：外用于皮肤的组合物的特征在于含有0.0001-60重量％的Adenophorea根的提取物作为活性成分。 组合物润湿皮肤，改善特应性皮炎或皮肤炎症，促进角质形成细胞的分化和丝聚蛋白的表达，促进神经酰胺的产生，并激活PPAR-α。
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公开(公告)号：KR101856976B1
公开(公告)日：2018-05-15
申请号：KR1020110125746
申请日：2011-11-29
Applicant: (주)아모레퍼시픽
Abstract: 본발명은피부표면반사광을측정하여제형에의한피부번들거림평가방법에관한것으로서, 보다구체적으로는제형시료를상기피부에도포하는단계; 상기도포된피부의표면반사광이미지를촬영하는단계; 상기이미지로부터광도를분석하는단계; 상기분석결과에서광량영역(intensity range)에서의광량합(intensity sum)을구하는단계; 및상기광량합을통해제형시료에의한피부번들거림(gloss) 정도를판정하는단계;를포함하는제형에의한피부번들거림평가방법에관한것으로, 서로다른제형들의피부번들거림에미치는영향을간소화된절차에의해육안으로보이는결과와가깝게객관적으로비교할수 있는제형간 비교에최적화된번들거림평가방법을제공할수 있다.
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公开(公告)号：KR101790163B1
公开(公告)日：2017-10-26
申请号：KR1020110046586
申请日：2011-05-18
Applicant: (주)아모레퍼시픽
Abstract: 본발명은피부의탄력정도및 제품사용에의한피부주름효능을평가할수 있는방법에관한것으로서, 보다구체적으로는, 눈가피부에인위적으로주름을유발한후 원상태로돌아오는회복력을측정함으로써피부탄력정도를간접적으로평가할수 있는방법에관한것이다.
Abstract translation: 本发明涉及一种能够评估由弹性皱纹效果和产品的对皮肤的程度，并且更具体地，通过测量弹性皮肤弹性程度而使人工的皱纹在眼睛周围的皮肤之后返回到原始状态的方法 间接评估系统性能的方法。
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公开(公告)号：KR1020170091567A
公开(公告)日：2017-08-09
申请号：KR1020170097086
申请日：2017-07-31
Applicant: (주)아모레퍼시픽
CPC classification number: A61K36/75 , A61K8/97 , A61Q19/005 , A61Q19/007
Abstract: 본발명은무라야패니쿨라타추출물을유효성분으로포함하는피부가려움증완화및 억제, 피부보습, 피부염증완화및 억제, 피부면역성강화, 피부과민반응개선또는아토피피부개선및 치료용조성물을개시한다.
Abstract translation: 本发明公开了一种村的同伴库拉其他皮肤瘙痒缓解包括提取物作为活性成分和抑制，皮肤保湿剂，皮肤炎症和抑制，皮肤免疫增强，皮肤致敏改善或特应性皮肤改善和治疗组合物。
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