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公开(公告)号：KR1020120010454A
公开(公告)日：2012-02-03
申请号：KR1020100072000
申请日：2010-07-26
Applicant: 건국대학교 산학협력단
Abstract: PURPOSE: A new porcine sapovirus VP1 and VP2 protein and a gene thereof are provided to produce a monoclonal antibody and to develop a vaccine. CONSTITUTION: A porcine sapovirus protein VP1 and VP2 are has a sequence of sequence number 1 or 3. A porcine sapovirus protein encoding the protein has a sequence of sequence number 2 or 4. A composition for diagnosing porcine sapovirus contains an antibody which is specific to VP1 and VP2. A gene vaccine to porcine sapovirus contains a gene encoding VP1 and VP2.
Abstract translation: 目的：提供新型猪皮肤病毒VP1和VP2蛋白及其基因以产生单克隆抗体并开发疫苗。 构成：猪皮病毒蛋白VP1和VP2具有序列号1或3的序列。编码该蛋白质的猪肝病毒蛋白具有序列号2或4的序列。用于诊断猪肝病毒的组合物含有抗体，其特异性为 VP1和VP2。 针对猪皮肤病毒的基因疫苗含有编码VP1和VP2的基因。
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公开(公告)号：KR101879936B1
公开(公告)日：2018-07-19
申请号：KR1020160075701
申请日：2016-06-17
Applicant: 건국대학교 산학협력단
IPC: C12N7/00 , A61K39/145 , A61K39/39 , G01N33/569
Abstract: 조류인플루엔자 H5N9 재조합바이러스및 이를포함하는백신에관한것이다. 본발명의재조합바이러스또는이를포함하는백신조성물은안정성이우수하고, 닭에서유의적으로높은항체역가를보이며, 조류인플루엔자바이러스에대한방어력이우수하다.
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公开(公告)号：KR101857863B1
公开(公告)日：2018-05-14
申请号：KR1020160075697
申请日：2016-06-17
Applicant: 건국대학교 산학협력단
IPC: C12N7/00 , A61K39/12 , A61K39/145 , A61K39/39 , G01N33/569
Abstract: 조류인플루엔자 H5N9 재조합바이러스및 이를포함하는백신에관한것이다. 본발명의재조합바이러스또는이를포함하는백신조성물은안정성이우수하고, 닭과오리에서유의적으로높은항체역가를보이며, 조류인플루엔자바이러스에대한방어력이우수하다.
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公开(公告)号：KR1020160036552A
公开(公告)日：2016-04-04
申请号：KR1020160034730
申请日：2016-03-23
Applicant: 건국대학교 산학협력단
IPC: C07K14/005 , C12N15/70 , A61K39/12
CPC classification number: A61K39/12 , A61K2039/523 , C12N2770/12034
Abstract: 본발명은백신으로사용할수 있는돼지생식기호흡기증후군바이러스의키메릭변이주에관한것이다. 본발명의키메릭바이러스변이주는돼지에서병원성이낮고안전성이높다. 강독성변이주의비구조단백질및 국내만연하는변이주의구조단백질을발현하여넓은방어범위를가지며, 어주번트없이사독백신단독으로만사용하여도높은항체가를얻을수 있는장점이있다. 따라서심각한경제적피해를유발하는양돈질병인돼지생식기호흡기증후군(PRRS)를효과적으로방어하는데이용할수 있다.
Abstract translation: 本发明涉及可用作疫苗的猪繁殖与呼吸综合征（PRRS）病毒的嵌合株。 嵌合病毒株在猪中致病性低，安全性高。 嵌合菌株通过表达高毒性菌株和常见家系菌株的结构蛋白的非结构蛋白质具有广泛的保护作用，并且即使嵌合菌株仅用作没有佐剂的杀死疫苗，也可获得高抗体滴度。 因此，本发明的嵌合菌株可以用于有效地防御PRRS，PRRS是引起严重经济损害的猪饲养疾病。
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Patent Agency Ranking
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公开(公告)号：KR101282990B1
公开(公告)日：2013-07-04
申请号：KR1020110051082
申请日：2011-05-30
Applicant: 건국대학교 산학협력단
IPC: C07H3/04 , C07H7/02 , A61K31/7016 , A61P31/16
Abstract: 본 발명은 녹차 및 녹차부산물로부터 추출ㆍ분획하여 얻어진 지용성 분획과 그 분획이 함유한 글리세롤 당지질 화합물을 유효성분으로 함유하는 인플루엔자질환의 예방 및 치료제에 관한 것이다.
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公开(公告)号：KR1020120132757A
公开(公告)日：2012-12-10
申请号：KR1020110051082
申请日：2011-05-30
Applicant: 건국대학교 산학협력단
IPC: C07H3/04 , C07H7/02 , A61K31/7016 , A61P31/16
CPC classification number: C07H15/04 , A01N43/02 , A23K20/163
Abstract: PURPOSE: An agent containing glycerol glycolipid compounds for preventing and treating influenza diseases is provided to ensure excellent antiviral effect in vivo and in vitro and to be used in a veterinary composition, feed additives, and anti-viral disinfection composition for preventing and treating animal diseases caused by viral infection. CONSTITUTION: A glycerol glycolipid compound is denoted by chemical formula 1 or 2. A pharmaceutical composition for preventing and treating influenza diseases contains the glycerol glycolipid compounds and a pharmaceutically acceptable carrier. The influenza diseases are caused by influenza virus A. A composition for preventing and treating influenza virus diseases contains a fat-soluble extract of green tea as an active ingredient. The fat soluble extract is prepared by hexane or dichloromethane. A veterinary composition for preventing and treating the influenza diseases contains the glycerol glycolipid compounds. A feed additive composition contains the glycerol glycolipid compounds.
Abstract translation: 目的：提供含有用于预防和治疗流感病毒的甘油糖脂化合物的药剂，以确保体内和体外优异的抗病毒作用，并用于兽医组合物，饲料添加剂和用于预防和治疗动物疾病的抗病毒消毒组合物 由病毒感染引起。 构成：甘油糖脂化合物由化学式1或2表示。用于预防和治疗流感病毒的药物组合物含有甘油糖脂化合物和药学上可接受的载体。 流感病毒是由流感病毒A引起的。用于预防和治疗流感病毒疾病的组合物含有绿茶的脂溶性提取物作为活性成分。 脂溶性提取物通过己烷或二氯甲烷制备。 用于预防和治疗流感病毒的兽用组合物含有甘油糖脂化合物。 饲料添加剂组合物含有甘油糖脂化合物。
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29.发明公开ＳＴＦ２-ＧｎＲＨ 융합 재조합 단백질을 포함하는 면역 거세용 백신 조성물 및 이를 이용한 동물의 면역 거세 방법 有权用于包含STF2-GNRH融合重组蛋白的免疫组化的疫苗组合物及其使用的动物免疫调节方法
公开(公告)号：KR1020120095167A
公开(公告)日：2012-08-28
申请号：KR1020110014670
申请日：2011-02-18
Applicant: 주식회사 고려비엔피 , 건국대학교 산학협력단
CPC classification number: A61K38/164 , C07K14/255 , C12N15/62 , Y10S514/885
Abstract: PURPOSE: A vaccine composition for immunity emasculating including STF2-GnRH fusion recombinant protein and an immunity emasculating method of animals are provided to enhance antigenicity, antibody formation effects, and sexual maturity inhibition effects of animals. CONSTITUTION: A vaccine composition for immunity emasculating includes a fusion recombinant protein in which STF2(Salmonella typhimurium flagellin fljB2) and GnRH(gonadotropin-releasing hormone) are fused. The STF2 has the amino acid sequence described in the sequence number 2. The GnRH has the amino acid sequence described in the sequence number 4. The STF2 and the GnRH are integrated through linkers. 1-20 GnRH are connected through linkers. The fusion recombinant protein has the amino acid sequence described in the sequence number 6. The vaccine composition additionally includes an adjuvant. The immunity emasculating method of the animal includes a step of dosing the vaccine composition to animals except for the human.
Abstract translation: 目的：提供包含STF2-GnRH融合重组蛋白的免疫前体灭活疫苗组合物和动物免疫去激活方法，以增强动物的抗原性，抗体形成效果和性成熟抑制作用。 构成：用于免疫去激素的疫苗组合物包括融合重组蛋白，其中STF2（鼠伤寒沙门氏菌鞭毛蛋白fljB2）和GnRH（促性腺激素释放激素）融合。 STF2具有序列号2中描述的氨基酸序列.GnRH具有序列号4中描述的氨基酸序列.STF2和GnRH通过接头整合。 1-20 GnRH通过连接器连接。 融合重组蛋白具有序列号6中描述的氨基酸序列。疫苗组合物另外包括佐剂。 动物的免疫去除方法包括将疫苗组合物给予除人之外的动物的步骤。
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