Abstract:
본 발명은 악성종양에 의해 유발되는 저산소증에 의한 신생혈관생성유도를 억제하기 위한 하기 화학식(Ⅰ)의 6-(1-옥소프로필)-5,8-디메톡시-1,4-나프토퀴논 화합물(이하 옥소화합물이라고 칭함) 및 이를 유효성분으로 함유하는 악성종양에 의해 유발되는 저산소증에 의한 신생혈관생성유도를 억제하기 위한 의약조성물에 관한 것이다. (Ⅰ) Naphthazarin, HIF-1α, VEGF,bFGF, 신생혈관생성, 저산소증
Abstract:
본발명은리더서열이제외된봉독-PLA2(bee venom-phospholipase A2; BV-PLA2) 아미노산서열을포함하는폴리펩티드를유효성분으로포함하는이상조절 T 세포활성저하관련질환의치료또는예방용약학적조성물에관한것이다. 본발명의분비형봉독유래포스포리파아제 A2(bee venom-phospholipase A2; 분비형 BV-PLA2)는조절 T 세포를활성화하는한편, Th1/Th17 분화를억제할수 있다. 따라서, 본발명의폴리펩티드는이상인조절 T 세포활성저하관련질환즉, 자가면역성질환, 알레르기성질환또는신경퇴행성질환의예방또는치료를위한약학적조성물로유용하게사용될수 있다.
Abstract:
The present invention provides a composition for preventing and treating prostate-related diseases containing an extract of Crataegus pinnatifida. The extract of the present invention has an anti-androgen effect and a prostate specific antigen controlling effect, and is effective for the treatment and prevention of the prostate-related diseases including prostatitis, prostatism, and prostate cancer.
Abstract:
PURPOSE: A composition containing a Phaseolus angularis extract for anti-androgen activity and/or prostate specific antigen (PSA) suppression is provided to suppress androgen and PSA and to effectively treat, alleviate, or prevent one or more diseases selected among alopecia, acne, prostate cancer, benign prostatic hyperplasia, and prostatitis. CONSTITUTION: An anti-androgenic pharmaceutical composition contains a Phaseolus angularis extract as an active ingredient. The extract is prepared using one or more solvents selected among water and C1-C4 alcohols. The pharmaceutical composition is used for preventing, treating, or alleviating one or more diseases selected among alopecia, acne, prostate cancer, benign prostatic hyperplasia, and prostatitis. A food composition for anti-androgen activity contains the extract. A composition for suppressing PSA contains the extract as an active ingredient.
Abstract:
PURPOSE: A composition containing Pinus koraiensis SIEB needle extract is provided to effectively suppress lipid accumulation in adipocytes and to ensure anti-obesity effect. CONSTITUTION: A composition for suppressing obesity contains Pinus koraiensis SIEB needle extract. A pharmaceutical composition for preventing or treating obesity contains the extract. The extract is prepared by steam distillation extraction. The steam distillation extraction comprises: a step of distilling Pinus koraiensis SIEB needles and purified water in a distillation tank at 70-500 Deg. C. for one hour to several days once or several times to obtain distillate; and a step of cooling and condensing the distillate. A food composition for preventing or treating obesity contains the Pinus koraiensis SIEB needle extract. [Reference numerals] (AA) Absorbance; (BB) Insulin; (CC) Oil(ug/ml)
Abstract:
PURPOSE: A pharmaceutical composition containing methyl gallate or pharmaceutically acceptable salt thereof is provided to treat disease caused by abnormal regulatory T cell activation. CONSTITUTION: A pharmaceutical composition for treating or preventing abnormal regulatory T cell activation-associated diseases contains methyl gallate of chemical formula 1 or pharmaceutically acceptable salt thereof. Methyl gallate is isolated from Moutan Cortex Radicis. The diseases include viral hepatitis type B, viral hepatitis type C, helicobacter pylori infectious disease, or cancer. An anticancer aid for suppressing anticancer drug resistance contains methyl gallate of chemical formula 1 or pharmaceutically acceptable salt thereof. The anticancer drug is therapeutic cancer vaccine. An anticancer composition contains the anticancer aid and anticancer drug.
Abstract:
본 발명은 백두옹 추출물을 유효성분으로 포함하는 항암제 투여로 인한 신장 독성 억제용 조성물에 관한 것이다. 보다 구체적으로, 본 발명은 백두옹 추출물을 유효성분으로 포함하는 항암제 투여로 인한 신장독성 억제용 조성물, 기존 항암제와 병용 투여하여 항암활성을 상승시키는 항암활성 증강용 조성물에 관한 것이다 .
Abstract:
본 발명은 백두옹 추출물을 유효성분으로 포함하는 항암제 투여로 인한 신장 독성 억제용 조성물에 관한 것이다. 보다 구체적으로, 본 발명은 백두옹 추출물을 유효성분으로 포함하는 항암제 투여로 인한 신장독성 억제용 조성물, 기존 항암제와 병용 투여하여 항암활성을 상승시키는 항암활성 증강용 조성물에 관한 것이다 .
Abstract:
PURPOSE: An anticancer composition containing cisplatin and Bojungbangdocktang is provided to reduce cytotoxicity and apoptosis of normal breast epithelial cells and enhance cytotoxicity and apoptosis of the breast cancers. CONSTITUTION: An anticancer composition for treating breast cancer contains cisplatin and Bojungbangdocktang as an active ingredient. The composition reduces cytotoxicity and apoptosis of normal epithelial cells and enhances cytotoxicity and apoptosis of breast cancer cells.