Abstract:
An Ecklonia stolonifera extract is provided to have aldose reductase and activity of inhibiting production of advanced glycation end product and diabetic complication and to be safe without toxicity and side effect. An Ecklonia stolonifera extract has aldose reductase and activation of inhibiting production of advanced glycation end product. The Ecklonia stolonifera extract is an Ecklonia stolonifera crude extract by extracting the Ecklonia stolonifera with lower alcohol of C1~C4. The Ecklonia stolonifera crude extract is Ecklonia stolonifera methanol extract.
Abstract:
PURPOSE: An aerial part extract of Aruncus dioicus and a novel compound isolated from the same are provided to treat leukemia or acute lymphatic leukemia including Jurkat T leukemia cells. CONSTITUTION: A pharmaceutical composition for treating leukemia contains a compound of structural formula I, II, III, IV, or V or a pharmaceutically acceptable salt thereof. The compound is isolated from an aerial part extract of Aruncus dioicus. The compound or the salt has antioxidation activity and/or cytotoxicity to Jurkat T cells.
Abstract:
본 발명은 불등가사리로부터 분리한 신규한 화학식 11의 화합물과 공지의 화합물 2 내지 18 및 이들을 유효성분으로 함유하여 항콜린에스테라아제 활성을 통한 알츠하이머 질환의 예방 또는 치료용 약제학적 조성물 및 알츠하이머 질환의 예방 또는 개선용 건강기능식품 조성물에 관한 것으로, 본 발명에 따른 상기 불등가사리 유래 화합물들은 적절한 아세틸콜린에스테라아제(AChE) 및 부틸콜린에스테라아제(BChE)에 대한 저해 활성을 통한 항콜린에스테라아제 활성을 나타냄으로써 알츠하이머 질환의 예방 및 치료를 잠재적 치료제로서 이용할 수 있는 효과가 있다.