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公开(公告)号:KR1020160021987A
公开(公告)日:2016-02-29
申请号:KR1020140107440
申请日:2014-08-19
Applicant: 전북대학교산학협력단
CPC classification number: A61L27/26 , A61L27/222 , A61L27/227 , A61L27/24 , A61L27/3604 , A61L27/3808 , A61L27/48 , A61L2430/16 , C08L89/00 , C08L89/06 , C08L5/08 , C08L5/04 , C08L1/00 , C08L3/02 , A61L27/20 , A61L27/22 , A61L2300/00 , A61L2430/00
Abstract: 본발명은조직공학용초박막실크피브로인/콜라겐복합이식체및 이의제조방법에관한것이다. 본발명에따른초박막실크피브로인/콜라겐복합이식체는정제된실크피브로인수용액, 콜라겐및 다양한생체재료의혼합사용으로인해세포독성이없고, 세포성장에영향을최소화할수 있어이식용초박막이식체로널리이용될수 있다.
Abstract translation: 本发明涉及用于组织工程的超薄膜丝素蛋白/胶原复合植入物及其制备方法。 根据本发明的超薄膜丝素蛋白/胶原复合植入物不具有细胞毒性,并且通过使用精制的丝素蛋白水解溶液,胶原蛋白和各种生物材料的混合物来最小化对细胞生长的影响,从而被广泛用作 用于植入的超薄植入物。
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公开(公告)号:KR1020130072983A
公开(公告)日:2013-07-02
申请号:KR1020110140635
申请日:2011-12-22
Applicant: 전북대학교산학협력단
Abstract: PURPOSE: A composition for treating cartilage damage containing 97 %v/v of moisture is provided to absorb shock by injecting into body, and to prevent dissolution by inflammatory reaction or toxic materials without cytotoxicity. CONSTITUTION: A composition for treating cartilage damage contains demineralized bone particle (DBP) gel and a costal chondrocyte composition. The DBP is derived from mammalian bone. The particle size of the DBP is 10-300 micrometer. The weight ratio of the DBP is 5-20 wt%. The composition has pH 6-7.
Abstract translation: 目的:提供一种用于治疗含有97%v / v水分的软骨损伤的组合物,以通过注射到体内吸收冲击,并防止炎症反应或有毒物质溶解而无细胞毒性。 构成:用于治疗软骨损伤的组合物含有脱矿质骨颗粒(DBP)凝胶和软骨软骨细胞组成。 DBP衍生自哺乳动物骨骼。 DBP的粒径为10-300微米。 DBP的重量比为5-20重量%。 组合物的pH为6-7。
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公开(公告)号:KR1020130072982A
公开(公告)日:2013-07-02
申请号:KR1020110140634
申请日:2011-12-22
Applicant: 전북대학교산학협력단
CPC classification number: A61K35/32 , A61K9/06 , A61K38/1841 , A61K38/30 , A61K38/488
Abstract: PURPOSE: A Demineralized bone particle (DBP) gel is provided to simplify preparation, to maintain gel form, and to ensure easy storage and biocompatibility. CONSTITUTION: A gel for chondrogenesis contains demineralized bone particle (DBP), pepsin, and acetic acid. The DBP is mammalian bone. The particle size of the DBP is 10-300 micrometer. The weight ratio of the DBP is 5-20 wt%. A composition for treating cartilage damage has pH 6-7.
Abstract translation: 目的:提供脱矿质骨颗粒(DBP)凝胶,以简化制备,保持凝胶形式,并确保易于储存和生物相容性。 构成:用于软骨形成的凝胶含有脱矿质骨颗粒(DBP),胃蛋白酶和乙酸。 DBP是哺乳动物骨。 DBP的粒径为10-300微米。 DBP的重量比为5-20重量%。 用于治疗软骨损伤的组合物具有pH6-7。
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