Abstract:
본명세서는중머리풀()을유효성분으로서포함하는조성물에관한것이다. 이러한본 명세서의조성물은산화적스트레스로부터신경세포를보호하고, 신경세포의사멸을억제하는효과를나타낸다. 또한, 세포내에서산화적스트레스의증가로인해발생하는세포사멸을억제하는항산화효소의발현을증가시킬수 있다. 따라서, 본명세서의조성물은산화적스트레스로부터신경세포의사멸로인하여발생될수 있는 2차적질병을예방, 개선또는치료하는효과를나타낼수 있어약학또는식품조성물로서사용될수 있다.
Abstract:
The present invention relates to a composition comprising an Amorpha fruticosa extract as an active ingredient for preventing or treating a renal disease. The composition according to the present invention has few side effects when applied to a human body and low possibility to generate resistance caused by long-term use by comprising natural products obtained from the nature as active ingredients. In particular, the composition of the present invention has superior efficacy for protecting kidney cells, thereby the composition can be valuably used for preventing or treating the renal disease. [Reference numerals] (AA) Cell survival rate; (BB) Concentration; (CC) Example (3-1) ug/ml; (DD) Example (4) uM; (EE) Example (3) uM
Abstract:
The present invention relates to a composition comprising an Amorpha fruticosa extract for PTP inhibition and PPAR activation. The composition of the present invention is capable of reducing blood glucose by increasing susceptibility to insulin as both of activation and expression of PTP1B are inhibited, and shows an outstanding activity for glucose uptake in muscle cells. [Reference numerals] (AA) Normal condition; (BB,FF,II,KK) Control group; (CC,GG) Example ; (DD,HH) Example ; (EE) Insulin resistance condition; (JJ,LL) Example
Abstract:
Provided is a composition for preventing, relieving or treating renal diseases, comprising Maillard browning reaction products as active ingredients wherein the products are acquired by reacting Ginsenoside Re, Panax genus plant extract including Ginsenoside Re, or glucose with an amino acid at 100-130 for 0.5-12 hours. [Reference numerals] (AA) Ginsenoside Re;(BB) Ginsenoside Rg_2;(CC) dehydration;(DD) Ginsenoside Rg_6;(EE) Ginsenoside F_4;(FF) Separated glucose + glycine;(GG) Maillard-type browning reaction