公开(公告)号：CA2761801A1

公开(公告)日：2010-11-18

申请号：CA2761801

申请日：2010-05-13

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA

Inventor： RABINOW BARRETT ,  BAIRSTOW SHAWN F ,  CHAUBAL MAHESH V ,  LEE SARAH ,  WERLING JANE

IPC: A61K9/14 ,  A61K31/337 ,  A61K47/34 ,  A61P35/00

Abstract: The present disclosure is directed to surface-modified particles and to methods of making and using the same. The surface-modified particles comprise a particle core and a coating associated with the particle core, wherein the particle core comprises an active agent, the coating comprises a surfactant having formula (I) or a salt thereof, and the surface-modified particle has an average size from about 1 nm to about 2,000 nm: