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公开(公告)号：ZA837517B
公开(公告)日：1984-10-31
申请号：ZA837517
申请日：1983-10-07
Applicant: CIBA GEIGY AG
Inventor： WENK PAUL , BREITENSTEIN WERNER , BAUMANN MARCUS
IPC: C07D307/81 , A61K20060101 , A61K31/395 , A61K31/40 , A61K31/4025 , A61K31/443 , A61K31/445 , A61K31/535 , A61P25/04 , A61P29/00 , C07D20060101 , C07D405/04 , C07D405/12 , C07D , A61K
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公开(公告)号：ZA8307517B
公开(公告)日：1984-10-31
申请号：ZA8307517
申请日：1983-10-07
Applicant: CIBA GEIGY AG
Inventor： WENK PAUL , BREITENSTEIN WERNER , BAUMANN MARCUS
IPC: C07D307/81 , A61K20060101 , A61K31/395 , A61K31/40 , A61K31/4025 , A61K31/443 , A61K31/445 , A61K31/535 , A61P25/04 , A61P29/00 , C07D20060101 , C07D405/04 , C07D405/12 , C07D , A61K
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公开(公告)号：NO841582A
公开(公告)日：1984-10-23
申请号：NO841582
申请日：1984-04-18
Applicant: CIBA GEIGY AG
Inventor： WENK PAUL , BAUMANN MARCUS , BREITENSTEIN WERNER
IPC: C07D307/83 , C07D405/04 , C07D
CPC classification number: C07D405/04 , C07D307/83
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公开(公告)号：DD212962A5
公开(公告)日：1984-08-29
申请号：DD25539883
申请日：1983-10-04
Applicant: CIBA GEIGY AG
Inventor： WENK PAUL , BREITENSTEIN WERNER , BAUMANN MARCUS
IPC: C07C45/46 , C07C205/37 , C07D295/096 , C07D295/112 , C07D295/155 , C07D295/194 , C07D307/79 , C07D307/83 , C07D405/04 , C07D307/82 , C07D307/78
Abstract: Benzofurans or 2,3-dihydrobenzofurans of the formula (I) in which R1 represents hydrogen or an aliphatic radical, R2 represents an amino group disubstituted by a bivalent aliphatic radical which is optionally interrupted by at least one hetero atom, and the aromatic ring may be additionally substituted, and the salts thereof, have anti-inflammatory and/or analgesic activities.
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公开(公告)号：DK470683A
公开(公告)日：1984-04-14
申请号：DK470683
申请日：1983-10-12
Applicant: CIBA GEIGY AG
Inventor： WENK PAUL , BREITENSTEIN WERNER , BAUMANN MARCUS
IPC: C07C69/157 , A61K31/05 , A61K31/085 , A61K31/11 , A61P25/04 , A61P29/00 , C07C27/00 , C07C39/02 , C07C41/00 , C07C43/178 , C07C45/00 , C07C45/46 , C07C47/27 , C07C59/76 , C07C67/00 , C07C213/00 , C07C215/76 , C07C219/34 , C07D207/32 , C07D207/325 , C07D295/096 , C07D295/112 , C07D295/155 , C07D307/83 , C07D405/04 , C07D471/04 , C07C , C07D
Abstract: Novel phenol derivatives, in particular those of the general formula in which R0 represents hydrogen or an acyl radical, R1 denotes hydroxymethyl, esterified or etherified hydroxymethyl, formyl or acetalised formyl, R2 represents hydrogen or an aliphatic radical, R3 represents an amino group which is disubstituted by two monovalent hydrocarbon radicals or by a divalent hydrocarbon radical which may be interrupted by at least one hetero atom and the aromatic ring A can additionally be substituted, and their salts and isomers, a process for their preparation and pharmaceutical preparations containing them and their use as active pharmaceutical compounds and/or in preparing pharmaceutical preparations.
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Patent Agency Ranking
公开(公告)号：NO833663L
公开(公告)日：1984-04-09
申请号：NO833663
申请日：1983-10-07
Applicant: CIBA GEIGY AG
Inventor： WENK PAUL , BREITENSTEIN WERNER , BAUMANN MARCUS
IPC: C07C45/46 , C07C205/37 , C07D295/096 , C07D295/112 , C07D295/155 , C07D295/194 , C07D307/79 , C07D307/83 , C07D405/04 , C07D
Abstract: Benzofurans or 2,3-dihydrobenzofurans of the formula (I) in which R1 represents hydrogen or an aliphatic radical, R2 represents an amino group disubstituted by a bivalent aliphatic radical which is optionally interrupted by at least one hetero atom, and the aromatic ring may be additionally substituted, and the salts thereof, have anti-inflammatory and/or analgesic activities.
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公开(公告)号：NO833663A
公开(公告)日：1984-04-09
申请号：NO833663
申请日：1983-10-07
Applicant: CIBA GEIGY AG
Inventor： WENK PAUL , BREITENSTEIN WERNER , BAUMANN MARCUS
IPC: C07C45/46 , C07C205/37 , C07D295/096 , C07D295/112 , C07D295/155 , C07D295/194 , C07D307/79 , C07D307/83 , C07D405/04 , C07D
CPC classification number: C07D295/194 , C07C45/46 , C07C205/37 , C07D295/096 , C07D295/112 , C07D295/155 , C07D307/79 , C07D307/83 , C07D405/04 , C07C49/84
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公开(公告)号：ZA8207845B
公开(公告)日：1983-06-29
申请号：ZA8207845
申请日：1982-10-27
Applicant: CIBA GEIGY AG
Inventor： WENK PAUL , BREITENSTEIN WERNER , BAUMANN MARCUS
IPC: C07D295/14 , A61K8/00 , A61K8/40 , A61K8/41 , A61K8/42 , A61K8/46 , A61K8/49 , A61P25/04 , A61P29/00 , A61P43/00 , A61Q17/04 , C07C67/00 , C07C227/00 , C07C227/18 , C07C229/42 , C07C233/00 , C07C235/34 , C07C313/00 , C07C317/46 , C07C323/20 , C07C323/56 , C07C323/60 , C07D207/08 , C07D207/32 , C07D207/333 , C07D209/08 , C07D295/096 , C07D295/112 , C07D295/155 , C07D295/185 , C07D307/83 , C07D405/04 , C07D471/04 , C07D , A61K
CPC classification number: A61K8/42 , A61K8/49 , A61K8/4913 , A61Q17/04 , C07D207/32 , C07D209/08 , C07D295/096 , C07D295/112 , C07D295/155 , C07D295/185 , C07D307/83 , C07D405/04
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公开(公告)号：AU8983682A
公开(公告)日：1983-05-05
申请号：AU8983682
申请日：1982-10-27
Applicant: CIBA GEIGY AG
Inventor： BREITENSTEIN WERNER , BAUMANN MARCUS , BOSSHARD HANS
IPC: C07D307/60 , C07C51/54 , C07C57/03 , C07C59/76 , C07C59/80 , C07D207/44 , C07D207/452 , C07D307/34 , C07D307/83 , C07D307/92 , C07D401/04 , C07D471/04 , A61K31/335
Abstract: Compounds of the formula I (I) in which R, R1 and R2 are as defined in patent claim 1, can be prepared by a novel process, for example by treating a salt of imidazo[1,2-a]pyridin-2(3H)-one with fumaric acid, maleic acid or maleic anhydride, in the presence of a base, and converting the product to a salt of 3-(1,2-dicarboxyethyl)-imidazo[1,2-a]pyridin-2(3H)-one, in the presence of a strong acid, reacting the latter salt with a compound CH2=C(R1)(R2) and treating the intermediate obtained with glacial acetic acid and sodium acetate. The compounds (I) can be converted, in a manner known per se, to corresponding imides having functional groups suitable for polymerization reactions of polycondensation reactions. These imides can be used to prepare photocrosslinkable polymers. The anhydrides (I) can also be used, in some cases, to prepare pharmaceutically active benzofuranones and homosalicylic acids by reaction with salts of suitable amines.
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公开(公告)号：NO823587A
公开(公告)日：1983-04-29
申请号：NO823587
申请日：1982-10-27
Applicant: CIBA GEIGY AG
Inventor： WENK PAUL , BREITENSTEIN WERNER , BAUMANN MARCUS
IPC: A61K31/34 , A61K31/343 , A61P25/04 , A61P29/00 , C07C59/76 , C07D307/83 , C07D471/04 , C07D
CPC classification number: C07D471/04 , C07C59/76 , C07D307/83
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