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    MULTILAYER FILMS FOR DELIVERY OF FLAVOR
    21.
    发明公开
    MULTILAYER FILMS FOR DELIVERY OF FLAVOR 有权
    MEHRSCHICHTIGE FILME ZUR AROMASTOFFFREISETZUNG

    公开(公告)号：EP2588200A1

    公开(公告)日：2013-05-08

    申请号：EP10731877.6

    申请日：2010-06-30

    Applicant: Colgate-Palmolive Company

    Inventor： BOYD, Thomas ,  GU, Ben ,  LEIGH, Leonora

    IPC: A61Q11/00 ,  A61K8/02 ,  A61K8/73 ,  A61K8/81

    CPC classification number: A61K8/0233 ,  A61K8/02 ,  A61K8/731 ,  A61K8/8135 ,  A61K2800/242 ,  A61K2800/244 ,  A61Q11/00

    Abstract: An oral care composition having enhanced flavor release comprising an orally acceptable carrier containing a first flavor and a multilayer film for extended or delayed flavor release, the multilayer film including at least a center layer containing a second flavor, the center layer positioned between two outer surface layers, each surface layer including a release modulating agent, the first and second flavor being the same or different. The film is adapted to adhere to an oral cavity surface and the outer surface layers may comprise a mucoadhesive polymer, e.g. carboxy polymethylene, polycarbophil or polyvinyl pyrrolidone, and a film forming polymer, eg. hydroxypropylmethyl cellulose (HPMC). Suitable release modulating agents include HPMC and polyvinyl acetate. The carrier may be a toothpaste or mouthwash.

    Abstract translation: 一种具有增强的风味释放的口腔护理组合物，其包含含有第一香料的口腔可接受的载体和用于延长或延迟的风味释放的多层膜，所述多层膜至少包含含有第二香料的中心层，所述中心层位于两个外表面 层，每个表面层包括释放调节剂，第一和第二香料相同或不同。 该膜适于粘附到口腔表面，并且外表面层可以包括粘膜粘附性聚合物，例如粘膜。 羧基聚亚甲基，聚卡波非或聚乙烯吡咯烷酮，以及成膜聚合物，例如。 羟丙基甲基纤维素（HPMC）。 合适的释放调节剂包括HPMC和聚乙酸乙烯酯。 载体可以是牙膏或漱口水。

    ORAL COMPOSITIONS AND METHOD FOR PRODUCING THEREOF
    25.
    发明公开
    ORAL COMPOSITIONS AND METHOD FOR PRODUCING THEREOF 审中-公开
    口服组合物及其制备方法

    公开(公告)号：EP2651518A1

    公开(公告)日：2013-10-23

    申请号：EP10793407.7

    申请日：2010-12-13

    Applicant: Colgate-Palmolive Company

    Inventor： GU, Ben ,  HASSAN, Mahmoud

    IPC: A61Q11/00 ,  A61K8/73 ,  A61K8/92

    CPC classification number: A61K8/044 ,  A61K8/0216 ,  A61K8/731 ,  A61K8/922 ,  A61Q11/00

    Abstract: Methods of preparing a dentifrice comprising polymer matrix film with a low solubility flavorant therein are disclosed. The methods comprise combining a polymer matrix film that are free of a low solubility flavorant with a dentifrice base comprising a low solubility flavorant and maintaining the combined polymer matrix film with the dentifrice base comprising low solubility flavorant for an amount of time sufficient for an amount of a low solubility flavorant to transfer from the dentifrice base comprising low solubility flavorant to the polymer matrix film Products comprising low solubility flavorant-free polymer matrix film in a dentifrice base comprising low solubility flavorant are also disclosed.

    Abstract translation: 公开了制备包含其中具有低溶解度食用香料的聚合物基质膜的洁牙剂的方法。 所述方法包括将不含低溶解度食用香料的聚合物基质薄膜与包含低溶解度食用香料的洁齿剂基料组合并且将组合的聚合物基质薄膜与包含低溶解度食用香料的洁齿剂基料保持足够的时间量， 从含有低溶解度食用香料的洁齿剂基料转移到聚合物基质薄膜的低溶解度食用香料也公开在包含低溶解度食用香料的洁牙剂基料中的包含低溶解度食用香料聚合物基质薄膜的产品。

    FLAVOR RELEASE FROM MULTILAYER FILM DURING BRUSHING
    26.
    发明公开
    FLAVOR RELEASE FROM MULTILAYER FILM DURING BRUSHING 有权
    AROMASTOFFFREISETZUNG AUS EINEM MEHRSCHICHTIGEN FILMWÄHRENDDESBÜRSTENS

    公开(公告)号：EP2588063A1

    公开(公告)日：2013-05-08

    申请号：EP10730011.3

    申请日：2010-06-30

    Applicant: Colgate-Palmolive Company

    Inventor： BOYD, Thomas ,  GU, Ben ,  WANG, Wei ,  LIN, Nora

    IPC: A61K8/02 ,  A61K8/73 ,  A61Q11/00 ,  A61K8/81

    CPC classification number: A61K8/0204 ,  A61K8/02 ,  A61K8/731 ,  A61K8/8135 ,  A61K2800/242 ,  A61K2800/244 ,  A61Q11/00

    Abstract: Oral care compositions which provide enhanced flavour release, and which comprise a multilayer film and an orally acceptable carrier. The carrier contains a first flavour and the film has a centre layer containing a second flavour disposed between two outer surface layers. The first and second flavours may be identical or different. Each layer for the film may comprise a film forming polymer, e.g. hydroxypropylmethyl cellulose. The outer layers may comprise a release modulating agent, e.g. polyvinyl acetate or hydroxyethyl cellulose. The carrier may be a dentifrice or mouthwash.

    Abstract translation: 提供增强的风味释放的口腔护理组合物，并且其包含多层膜和口服可接受的载体。 载体含有第一种风味，并且膜具有包含设置在两个外表面层之间的第二香料的中心层。 第一和第二种口味可以相同或不同。 膜的每个层可以包括成膜聚合物，例如， 羟丙基甲基纤维素。 外层可以包含释放调节剂，例如。 聚乙酸乙烯酯或羟乙基纤维素。 载体可以是洁齿剂或漱口剂。

    MULTILAYER FILMS FOR DELIVERY OF FLAVOR
    27.
    发明授权
    MULTILAYER FILMS FOR DELIVERY OF FLAVOR 有权
    用于传递风味的多层膜

    公开(公告)号：EP2588200B1

    公开(公告)日：2018-02-28

    申请号：EP10731877.6

    申请日：2010-06-30

    Applicant: Colgate-Palmolive Company

    Inventor： BOYD, Thomas ,  GU, Ben ,  LEIGH, Leonora

    IPC: A61Q11/00 ,  A61K8/02 ,  A61K8/73 ,  A61K8/81

    CPC classification number: A61K8/0233 ,  A61K8/02 ,  A61K8/731 ,  A61K8/8135 ,  A61K2800/242 ,  A61K2800/244 ,  A61Q11/00

    Abstract: An oral care composition having enhanced flavor release comprising an orally acceptable carrier containing a first flavor and a multilayer film for extended or delayed flavor release, the multilayer film including at least a center layer containing a second flavor, the center layer positioned between two outer surface layers, each surface layer including a release modulating agent, the first and second flavor being the same or different. The film is adapted to adhere to an oral cavity surface and the outer surface layers may comprise a mucoadhesive polymer, e.g. carboxy polymethylene, polycarbophil or polyvinyl pyrrolidone, and a film forming polymer, eg. hydroxypropylmethyl cellulose (HPMC). Suitable release modulating agents include HPMC and polyvinyl acetate. The carrier may be a toothpaste or mouthwash.

    ORAL COMPOSITIONS AND METHOD FOR PRODUCING THEREOF
    29.
    发明公开
    ORAL COMPOSITIONS AND METHOD FOR PRODUCING THEREOF 审中-公开
    ORALE ZUSAMMENSETZUNGEN UND HERSTELLUNGSVERFAHRENDAFÜR

    公开(公告)号：EP2651517A1

    公开(公告)日：2013-10-23

    申请号：EP10793406.9

    申请日：2010-12-13

    Applicant: Colgate-Palmolive Company

    Inventor： GU, Ben ,  HASSAN, Mahmoud

    IPC: A61Q11/00 ,  A61K8/73 ,  A61K8/92

    CPC classification number: A61K8/0204 ,  A61K8/0216 ,  A61K8/27 ,  A61K8/731 ,  A61K8/922 ,  A61K2800/92 ,  A61Q11/00

    Abstract: Methods of preparing a dentifrice comprising polymer matrix film with a low solubility flavorant therein are disclosed. The methods comprise combining a polymer matrix film that are free of a low solubility flavorant with a dentifrice base comprising a low solubility flavorant and maintaining the combined polymer matrix film with the dentifrice base comprising low solubility flavorant for an amount of time sufficient for an amount of a low solubility flavorant to transfer from the dentifrice base comprising low solubility flavorant to the polymer matrix film Products comprising low solubility flavorant-free polymer matrix film in a dentifrice base comprising low solubility flavorant are also disclosed.

    Abstract translation: 公开了包含其中具有低溶解性食用香料的聚合物基质膜的洁齿剂的制备方法。 所述方法包括将不含低溶解度调味剂的聚合物基质膜与包含低溶解度调味剂的洁牙剂基质组合，并将包含低溶解度调味剂的洁牙剂底部的组合聚合物基质膜保持足够的量 还公开了一种从包含低溶解度调味剂的洁牙剂基质转移到聚合物基质膜的低溶解度食用香料。还公开了包含低溶解性食用香料的洁牙剂底物中含有低溶解度无味剂的聚合物基质膜的产品。

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