公开(公告)号：WO2010134903A1

公开(公告)日：2010-11-25

申请号：PCT/US2009/044336

申请日：2009-05-18

Applicant: COLGATE-PALMOLIVE COMPANY ,  PILCH, Shira ,  WILLIAMS, Malcolm

Inventor： PILCH, Shira ,  WILLIAMS, Malcolm

IPC: A61K8/81 ,  A61Q11/00

CPC classification number: A61K8/8164 ,  A61K2800/57 ,  A61Q11/00

Abstract: The present invention provides an oral composition comprising a polymer, preferably a copolymer of methyl vinyl ether and maleic anhydride, attached to a sweetening agent via a cleavable linker, comprising a covalent bond, preferably an ester bond or an amide bond wherein the polymer is capable of attaching to a surface in an oral cavity, and the cleavable linker is cleavable in the oral cavity to release the sweetening agent.

Abstract translation: 本发明提供一种口服组合物，其包含聚合物，优选甲基乙烯基醚和马来酸酐的共聚物，其通过可切割接头连接到甜味剂上，所述可切割接头包含共价键，优选酯键或酰胺键，其中聚合物能够 附着到口腔中的表面，并且可切割接头在口腔中可切割以释放甜味剂。

公开(公告)号：WO2020081050A1

公开(公告)日：2020-04-23

申请号：PCT/US2018/055971

申请日：2018-10-16

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： NORTH, Michael ,  DONG, Rong ,  PIMENTA, Paloma ,  PILCH, Shira

IPC: A61Q11/00 ,  A61K8/73 ,  A61K8/81

Abstract: Film forming compositions and methods for preventing stains and increasing shine and gloss of teeth. The film forming compositions may include a polymer, such as a hydrophobic polymer, and an orally acceptable solvent. The hydrophobic polymer may include an acrylate component and a hydrophobic group coupled with one another. The hydrophobic group may include an alkyl chain, a polyethylene glycol, a polypropylene, a polyester, a polyorthoester, a phospholipid, a long chain fatty acid, a vinyl chloride, fluorethylene, a siloxane, a urethane, an octylacrylamide, a butylaminoethyl, a styrene, and combinations thereof.

公开(公告)号：WO2020081049A1

公开(公告)日：2020-04-23

申请号：PCT/US2018/055970

申请日：2018-10-16

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： DONG, Rong ,  WANG, Wei ,  PIMENTA, Paloma ,  SANTARPIA III, Ralph Peter ,  PILCH, Shira

IPC: A61Q11/00 ,  A61K8/73 ,  A61K8/81 ,  A61K8/97 ,  A61K8/21

Abstract: A film forming composition and methods for preventing acid erosion of teeth and preventing the formation of caries on teeth are disclosed. The film forming composition may include a hydrophobic copolymer, a fluoride compound, and an orally acceptable solvent. The film forming composition may also include a cellulose derivative, a rosin, a fluoride compound, and an orally acceptable solvent.

公开(公告)号：WO2014088534A1

公开(公告)日：2014-06-12

申请号：PCT/US2012/067541

申请日：2012-12-03

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： PAPPAS, Iraklis ,  NESTA, Jason ,  PILCH, Shira

IPC: C08B37/00 ,  C08J3/075 ,  C08J3/24 ,  C08L5/00 ,  A61Q11/00 ,  A61K8/73 ,  A61K8/04

CPC classification number: A61K8/73 ,  A61K8/042 ,  A61K8/20 ,  A61Q11/00 ,  C08B37/006 ,  C08J3/075 ,  C08J3/24 ,  C08J2305/00 ,  C08L5/00

Abstract: Disclosed is a method of manufacturing a fluid gel, the method comprising adding metal cations to the gellant dispersion while retaining the pH at no greater than 3; and adding a pH modifying agent to the gellant dispersion to increase the pH of the gellant dispersion to greater than 3.

Abstract translation: 公开了一种制造流体凝胶的方法，该方法包括将金属阳离子添加到凝胶分散体中，同时保持pH不大于3; 并将pH调节剂加入到胶凝剂分散体中以将胶凝剂分散体的pH增加至大于3。

公开(公告)号：WO2013089734A1

公开(公告)日：2013-06-20

申请号：PCT/US2011/065125

申请日：2011-12-15

Applicant: COLGATE-PALMOLIVE COMPANY ,  PIMENTA, Paloma ,  MIKSA, Davide ,  PILCH, Shira ,  REGE, Aarti ,  SULLIVAN, Richard

Inventor： PIMENTA, Paloma ,  MIKSA, Davide ,  PILCH, Shira ,  REGE, Aarti ,  SULLIVAN, Richard

IPC: A61K8/43 ,  A61K8/44 ,  A61K8/73 ,  A61K8/81 ,  A61Q11/00

CPC classification number: A61K8/8152 ,  A61K8/21 ,  A61K8/44 ,  A61K8/73 ,  A61K8/731 ,  A61K2800/594 ,  A61Q11/00

Abstract: Described herein are aqueous oral care compositions comprising (a) an effective amount of a basic amino acid in free or orally acceptable salt form; and (b) a polymer system comprising (i) a cellulosic polymer, (ii) a gum polymer, and (iii) a polyacrylate polymer or co-polymer; and methods of making and using the same.

Abstract translation: 本文描述的是水性口腔护理组合物，其包含（a）有效量的游离或口服可接受的盐形式的碱性氨基酸; 和（b）聚合物体系，其包含（i）纤维素聚合物，（ii）胶聚合物，和（iii）聚丙烯酸酯聚合物或共聚物; 以及制作和使用它们的方法。

公开(公告)号：WO2013089721A1

公开(公告)日：2013-06-20

申请号：PCT/US2011/065024

申请日：2011-12-15

Applicant: COLGATE-PALMOLIVE COMPANY ,  HOURIGAN, Regina ,  GAFUR, Rehana ,  MATTAI, Jairajh ,  MASTERS, James ,  DU-THUMM, Laurence ,  PILCH, Shira

Inventor： HOURIGAN, Regina ,  GAFUR, Rehana ,  MATTAI, Jairajh ,  MASTERS, James ,  DU-THUMM, Laurence ,  PILCH, Shira

IPC: A01N31/08 ,  A61K8/34 ,  A61K31/05 ,  A01P1/00 ,  A61P31/04

CPC classification number: A01N31/08 ,  A61K8/34 ,  A61K8/347 ,  A61K31/05 ,  A61Q11/00 ,  A61Q17/005 ,  Y02A50/473 ,  A01N2300/00 ,  A61K2300/00

Abstract: An antibacterial composition comprising thymol and totarol. This combination provides synergistic effect against gram negative and gram positive bacteria.

Abstract translation: 包含百里酚和totarol的抗菌组合物。 这种组合对革兰氏阴性和革兰氏阳性细菌具有协同作用。

公开(公告)号：WO2012087325A1

公开(公告)日：2012-06-28

申请号：PCT/US2010/061959

申请日：2010-12-23

Applicant: COLGATE-PALMOLIVE COMPANY ,  PIMENTA, Paloma ,  JOZIAK, Marilou T. ,  PILCH, Shira

Inventor： PIMENTA, Paloma ,  JOZIAK, Marilou T. ,  PILCH, Shira

IPC: A61K8/73 ,  A61K8/81 ,  A61Q11/00

CPC classification number: A61K8/731 ,  A61K8/73 ,  A61K8/8147 ,  A61K2800/594 ,  A61Q11/00

Abstract: Described herein are aqueous compositions comprising polymers, which deliver a polymer film to surfaces of the oral cavity to relieve dry mouth; and methods of preparing and using the same.

Abstract translation: 本文描述的是包含聚合物的水性组合物，其将聚合物膜递送到口腔的表面以减轻口干; 以及制备和使用它们的方法。

公开(公告)号：WO2011088199A2

公开(公告)日：2011-07-21

申请号：PCT/US2011/021112

申请日：2011-01-13

Applicant: COLGATE-PALMOLIVE COMPANY ,  PIMENTA, Paloma ,  PILCH, Shira ,  MASTERS, James ,  WON, Betty

Inventor： PIMENTA, Paloma ,  PILCH, Shira ,  MASTERS, James ,  WON, Betty

CPC classification number: A61Q11/00 ,  A61K8/27 ,  A61K8/442 ,  A61K8/463 ,  A61K8/86

Abstract: An oral care composition and method are described in which the composition includes a film or a plurality of film fragments entrained in a carrier. The film or plurality of film fragments comprises zinc oxide. The composition and methods provide benefits including increased stability and shelf-life ensuring the delivery and bioavailability of zinc oxide.

Abstract translation: 描述了一种口腔护理组合物和方法，其中组合物包含夹带在载体中的膜或多个膜片段。 膜或多个膜片段包含氧化锌。 组合物和方法提供益处，包括提高稳定性和保质期，确保氧化锌的输送和生物利用度。

公开(公告)号：WO2011084676A2

公开(公告)日：2011-07-14

申请号：PCT/US2010/060975

申请日：2010-12-17

Applicant: COLGATE-PALMOLIVE COMPANY ,  PIMENTA, Paloma ,  PILCH, Shira ,  MASTERS, James

Inventor： PIMENTA, Paloma ,  PILCH, Shira ,  MASTERS, James

IPC: A61K8/25 ,  A61Q11/00

CPC classification number: A61K8/25 ,  A61K2800/28 ,  A61K2800/56 ,  A61Q11/00

Abstract: Described herein are compositions which modulate entrapment and release of flavorants and other actives in dental formulations.

Abstract translation: 本文描述的是调节牙科制剂中调味剂和其它活性物质的捕获和释放的组合物。

公开(公告)号：WO2011053273A1

公开(公告)日：2011-05-05

申请号：PCT/US2009/062017

申请日：2009-10-26

Applicant: COLGATE-PALMOLIVE COMPANY ,  PILCH, Shira ,  MASTERS, Jim ,  WON, Betty

Inventor： PILCH, Shira ,  MASTERS, Jim ,  WON, Betty

IPC: A61K8/27 ,  A61K8/41 ,  A61Q11/02

CPC classification number: A61Q11/00 ,  A61K8/22 ,  A61K8/27 ,  A61K8/365 ,  A61K8/44 ,  A61K8/4926 ,  A61K2800/51

Abstract: Disclosed are oral care compositions and the use of such oral care compositions for treating or preventing oral malodor. Also disclosed are methods for treatment or prevention of oral malodor. The oral care compositions include serine in an amount effective to reduce oral malodor caused by hydrogen sulfide and/or indole.

Abstract translation: 公开了口腔护理组合物和这种口腔护理组合物用于治疗或预防口腔恶臭的用途。 还公开了治疗或预防口腔恶臭的方法。 口腔护理组合物包括有效降低由硫化氢和/或吲哚引起的口腔恶臭的量的丝氨酸。