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    HEMOCOMPATIBILITY MODIFIERS FOR CROSS-LINKED POLYMERIC MATERIAL
    23.
    发明专利
    HEMOCOMPATIBILITY MODIFIERS FOR CROSS-LINKED POLYMERIC MATERIAL 未知

    公开(公告)号：CA2908202A1

    公开(公告)日：2014-10-09

    申请号：CA2908202

    申请日：2014-03-31

    Applicant: CYTOSORBENTS CORP

    Inventor： GOLOBISH THOMAS D ,  CAPPONI VINCENT J ,  CLAY DAVID R

    IPC: A61M1/34 ,  A61M1/36 ,  B01J20/26

    Abstract: The invention concerns methods of treating blood, blood product, or physiologic fluid to provide at least one of (i) increasing shelf life of the blood, blood product or physiologic fluid, (ii) maintaining freshness of new blood, blood product or physiologic fluid, and (iii) removing undesirable molecules from the blood, blood product or physiologic fluid; said method comprising contacting said blood, blood product or physiologic fluid with a sorbent, said sorbent being primarily in a plurality of solid forms and comprising a cross-linked polymeric material having a plurality of at least one of (1) zwitterionic moieties and (2) oligo(ethylene glycol) moieties attached to the surface of said cross-linked polymeric material.

    METHODS OF USING POLYMERS
    24.
    发明专利
    METHODS OF USING POLYMERS 未知

    公开(公告)号：CA2877536A1

    公开(公告)日：2014-01-03

    申请号：CA2877536

    申请日：2013-06-28

    Applicant: CYTOSORBENTS CORP

    Inventor： CHAN PHILLIP P ,  CAPPONI VINCENT J ,  GOLOBISH THOMAS D ,  ALI HUMAYRA BEGUM

    IPC: A61M1/34 ,  C09K23/38 ,  C09K23/48 ,  C09K23/52

    Abstract: Provided herein are materials and methods of reducing contamination in a biological substance or treating contamination in a subject by one or more toxins comprising contacting the biological substance with an effective amount of a sorbent capable of sorbing the toxin, wherein the sorbent comprises a plurality of pores ranging from 50Å to 40,000Å with a pore volume of 0.5 cc/g to 5.0 cc/g and a size of 0.05 mm to 2 cm and sorbing the toxin. Also provided are kits to reduce contamination by one or more toxins in a biological substance comprising a sorbent capable of sorbing a toxin, wherein the sorbent comprises a plurality of pores ranging from 50Å to 40,000Å with a pore volume of 0.5 cc/g to 5.0 cc/g and a size of 0.05 mm to 2 cm and a vessel to store said sorbent when not in use together with packaging for same.

    METHODS OF USING TOXIN ABSORBING POLYMERS
    28.
    发明专利
    METHODS OF USING TOXIN ABSORBING POLYMERS 未知

    公开(公告)号：CA2877536C

    公开(公告)日：2020-12-29

    申请号：CA2877536

    申请日：2013-06-28

    Applicant: CYTOSORBENTS CORP

    Inventor： CHAN PHILLIP P ,  CAPPONI VINCENT J ,  GOLOBISH THOMAS D ,  ALI HUMAYRA BEGUM

    IPC: A61K31/765 ,  A61K9/14 ,  A61P7/00 ,  A61P39/00 ,  A61P39/04 ,  C09K23/38 ,  C09K23/48 ,  C09K23/52

    Abstract: Provided herein are materials and methods of reducing contamination in a biological substance or treating contamination in a subject by one or more toxins comprising contacting the biological substance with an effective amount of a sorbent capable of sorbing the toxin, wherein the sorbent comprises a plurality of pores ranging from 50Å to 40,000Å with a pore volume of 0.5 cc/g to 5.0 cc/g and a size of 0.05 mm to 2 cm and sorbing the toxin. Also provided are kits to reduce contamination by one or more toxins in a biological substance comprising a sorbent capable of sorbing a toxin, wherein the sorbent comprises a plurality of pores ranging from 50Å to 40,000Å with a pore volume of 0.5 cc/g to 5.0 cc/g and a size of 0.05 mm to 2 cm and a vessel to store said sorbent when not in use together with packaging for same.

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