公开(公告)号：GB2356701B

公开(公告)日：2001-09-19

申请号：GB0105344

申请日：1998-03-04

Applicant: HOWARD FOUNDATION

Inventor： BONE RICHARD ANDREW ,  LANDRUM JOHN THOMAS ,  HUANG WENLUE ,  ORTA CARLOS MANUEL

IPC: A61B3/02 ,  A61B3/12

公开(公告)号：AU6631198A

公开(公告)日：1998-09-29

申请号：AU6631198

申请日：1998-03-04

Applicant: HOWARD FOUNDATION

Inventor： BONE RICHARD ANDREW ,  LANDRUM JOHN THOMAS ,  HUANG WENLUE ,  ORTA CARLOS MANUEL

IPC: A61B3/02 ,  A61B3/06 ,  G01J3/08

Abstract: A flicker photometer comprises generating means (1, 8, 4) for generating two beams of light of different colours. Both beams are directed to a viewing means (190), and a subject can vary the intensity of light from one beam relative to the other. The colour of the light seen by the subject is caused to alternate. The performance of the photometer is improved by screens which scatter light before it reaches the subject. A first of the screens (186, 188) reflects light from one beam, whilst a second screen (b) is translucent, and thus transmits light from the other. If light of wavelengths to which the eye is less sensitive is passed through the second screen, whilst light of a wavelength to which the eye is more sensitive passes through the first screen, the screens help to make it practicable for the generating means to use a single lamp (1) to produce the light for both beams.

公开(公告)号：CA2283778A1

公开(公告)日：1998-09-17

申请号：CA2283778

申请日：1998-03-04

Applicant: HOWARD FOUNDATION

Inventor： HUANG WENLUE ,  LANDRUM JOHN THOMAS ,  ORTA CARLOS MANUEL ,  BONE RICHARD ANDREW

IPC: A61B3/02 ,  A61B3/06 ,  G01J3/08

Abstract: A flicker photometer comprises generating means (1, 8, 4) for generating two beams of light of different colours. Both beams are directed to a viewing means (190), and a subject can vary the intensity of light from one beam relative to the other. The colour of the light seen by the subject is caused to alternate by a shutter (18) which is rotated about an axis by a motor, the shutter having a portion which extends non-perpendicularly relative to the axis to facilitate a compact construction of photometer. The performance of the photometer is improved by screens which scatter light before it reaches the subject. A first of the screens reflectes light from one beam, whilst a second screen transmits light from the other. If light of wavelengths to which the eye is less sensitive is passed through the second screen, whilst light of a wavelength to which the eye is more sensitive passes through the first screen, the screens help to make it practicable for the generating means to use a single lamp (1) to produce the light for both beams.

公开(公告)号：GB2323163A

公开(公告)日：1998-09-16

申请号：GB9804448

申请日：1998-03-04

Applicant: HOWARD FOUNDATION

Inventor： BONE RICHARD ANDREW ,  LANDRUM JOHN THOMAS ,  HUANG WENLUE ,  ORTA CARLOS MANUEL

IPC: A61B3/02 ,  A61B3/06 ,  G01J3/08

Abstract: In a flicker photometer to measure the level of macular pigment in the eye of a subject, a light source 1 produces two beams of light of different wavelengths that are alternately directed to the eyepiece 2 via a rotating chopper 18. The chopper either allows light of one wavelength to pass through it after attenuation by the wedge-shaped filter 20, or for light reflected from mirrors 10,12 and 14 to be reflected from its bevelled edges 186,188 and onto the eyepiece for viewing. This allows for a compact chopper arrangement. The subject adjusts the position of the attenuating filter 20 and hence the intensity of one of the beams until no or minimal flicker is observed by the subject. The chopper 18 alternately allows transmission 2 of attenuated light via window 6 to the eyepiece or reflects light via its bevelled edge (186,188,figure 18) to the eyepiece. Use of the bevelled edge of the chopper leads to a compact layout.

公开(公告)号：AU5907896A

公开(公告)日：1996-12-30

申请号：AU5907896

申请日：1996-06-07

Applicant: HOWARD FOUNDATION

Inventor： HOWARD ALAN NORMAN ,  LANDRUM JOHN THOMAS ,  BONE RICHARD ANDREW

IPC: A23L33/00 ,  A23L33/15 ,  A23L33/155 ,  A61K31/045 ,  A61K31/047 ,  A61K31/07 ,  A61K31/12 ,  A61K31/22 ,  A61K31/23 ,  A61K31/355 ,  A61K31/375 ,  A61K33/04 ,  A61K33/24 ,  A61K33/34

Abstract: The carotenoids lutein and zeaxanthin are used either separately or in combination to treat age-related macular degeneration (AMD). The carotenoids are administered in the form of a pharmaceutical preparation, e.g. a capsule or alternatively as a food e.g. a genetically engineered tomato producing enhanced levels of carotenoid. High dosages of lutein and zeaxanthin are needed to ensure high serum levels necessary for take up of the carotenoids by the macula.

公开(公告)号：GB2301775A

公开(公告)日：1996-12-18

申请号：GB9611967

申请日：1996-06-07

Applicant: HOWARD FOUNDATION

Inventor： HOWARD ALAN NORMAN ,  BONE RICHARD ANDREW ,  LANDRUM JOHN THOMAS

IPC: A23L33/00 ,  A23L33/15 ,  A23L33/155 ,  A61K31/045 ,  A61K31/047 ,  A61K31/07 ,  A61K31/12 ,  A61K31/22 ,  A61K31/23 ,  A61K31/355 ,  A61K31/375 ,  A61K33/04 ,  A61K33/24 ,  A61K33/34

Abstract: The carotenoids lutein and zeaxanthin are used either separately or in combination to treat age-related macular degeneration (AMD). The carotenoids are administered in the form of a pharmaceutical preparation, e.g. a capsule or alternatively as a food e.g. a genetically engineered tomato producing enhanced levels of carotenoid. High dosages of lutein and zeaxanthin are needed to ensure high serum levels necessary for take up of the carotenoids by the macula.