WATER MISCIBLE SOLVENT BASED PROCESS FOR PURIFYING A BISPHOSPHATE
    23.
    发明公开
    WATER MISCIBLE SOLVENT BASED PROCESS FOR PURIFYING A BISPHOSPHATE 有权
    ON用于纯化的二磷酸酯与水混溶的溶剂基于过程

    公开(公告)号:EP2382222A1

    公开(公告)日:2011-11-02

    申请号:EP09796246.8

    申请日:2009-12-21

    CPC classification number: C07F9/12 C08K5/523 C09K21/12

    Abstract: There is provided herein a process for purifying bisphosphate comprising solvating a molten bisphosphate in a mixture of water and water miscible solvent; cooling the solution over a period and to a temperature that provides for crystallization of solid product; increasing the pH of the solution prior to, and/or during, and/or after the initiation of crystallization, and/or after crystallization, by the addition of a base; and after crystallization is complete, separating solid product from the solution; washing the separated solid product in the same and/or different mixture of water and water miscible solvent; and, washing the solid product which has been washed in the mixture with water.

Patent Agency Ranking