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公开(公告)号：WO2014033574A3
公开(公告)日：2014-04-24
申请号：PCT/IB2013056532
申请日：2013-08-09
Applicant: KIMBERLY CLARK CO
Inventor： KOENIG DAVID W , SCHOLL NEIL T , TOPOLKARAEV VASILY A , VANDEN HEUVEL AMY L
CPC classification number: A61K35/744 , A61K9/0034 , A61K35/742 , A61K35/745 , A61K35/747 , A61K36/064 , A61K36/48 , A61K36/899 , A61K38/48 , A61K2300/00
Abstract: The present invention relates to a personal care product comprising a protein matrix wherein said protein matrix comprises at least one protein, at least one probiotic and a carrier fluid. The present invention also relates to the personal care product being a feminine care product particularly aimed at female urogenital health to treat or prevent vaginal infections. Oral and sinus infections, however, may also be benefited by the composition.
Abstract translation: 本发明涉及包含蛋白质基质的个人护理产品，其中所述蛋白质基质包含至少一种蛋白质，至少一种益生菌和载体流体。 本发明还涉及作为女性护理产品的个人护理产品，特别是针对女性泌尿生殖健康来治疗或预防阴道感染。 然而，口服和鼻窦感染也可能受益于组合物。
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公开(公告)号：WO2012077005A2
公开(公告)日：2012-06-14
申请号：PCT/IB2011054838
申请日：2011-10-31
Applicant: KIMBERLY CLARK CO , TOPOLKARAEV VASILY A , SCHOLL NEIL T
Inventor： TOPOLKARAEV VASILY A , SCHOLL NEIL T
CPC classification number: A61K47/42 , A01N25/28 , A61K8/0208 , A61K8/645 , A61Q17/005 , A61Q19/10 , C08K5/0016 , C08K5/0025 , C08K5/053 , C08K5/09 , C08K5/1515 , C08L89/00 , A01N25/10 , A01N65/00
Abstract: A melt-processed protein composition formed from a protein, plasticizer, and an electrophilic reagent is provided. The electrophilic reagent, for instance, may be selected to undergo a nucleophilic addition reaction with free sulfhydryl and/or thiyl radicals to help minimize the formation of disulfide crosslinking bonds that could otherwise lead to protein aggregation during melt processing. To enhance the degree to which the electrophilic reagent can limit crosslinking, a plasticizer is also employed that helps to mediate the adsorption of the electrophilic reagent into the internal structure of the protein, where it can be more stably retained. Furthermore, the temperature and shear rate employed during melt blending may also be selected to be relatively low to help limit polypeptide dissociation, thereby minimizing the impact of aggregation and embrittlement.
Abstract translation: 提供由蛋白质，增塑剂和亲电子试剂形成的熔融加工的蛋白质组合物。 例如，可以选择亲电子试剂以进行与游离巯基和/或硫酰基的亲核加成反应，以帮助最小化二硫化物交联键的形成，否则所述二硫键会在熔融加工期间导致蛋白质聚集。 为了提高亲电子试剂限制交联的程度，还使用增塑剂，其帮助介导亲电试剂吸附到蛋白质的内部结构中，在那里它可以更稳定地保留。 此外，熔融共混过程中使用的温度和剪切速率也可以选择为相对较低，以帮助限制多肽解离，从而使聚集和脆化的影响最小化。
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23.发明申请METHODS OF MAKING DISPOSABLE PRODUCTS HAVING MATERIALS HAVING SHAPE-MEMORY 审中-公开制造具有形状记忆材料的可处理产品的方法
公开(公告)号：WO0247595A9
公开(公告)日：2003-04-17
申请号：PCT/US0148073
申请日：2001-12-13
Applicant: KIMBERLY CLARK CO
Inventor： TOPOLKARAEV VASILY A , ODORZYNSKI THOMAS WALTER , SOERENS DAVE A , GARVEY MICHAEL J , UITENBROEK DUANE GIRARD
IPC: A61F13/15
CPC classification number: A61F13/15593
Abstract: The present invention relates to shape deformable materials, which are capable of (1) being deformed, (2) storing an amount of shape deformation, and (3) recovering at least a portion of the shape deformation when exposed to electromagnetic radiation (EMR) energy. The shape deformable materials can advantageously be in the form of films, fibers, filaments, strands, nonwovens, and pre-molded elements. The shape deformable materials of the present invention may be used to form products, which are both disposable and reusable. More specifically, the shape deformable materials of the present invention may be used to produce products such as disposable diapers, training pants, incontinence products, and feminine care products.
Abstract translation: 本发明涉及能够（1）变形的形状可变形材料，（2）存储一定量的形状变形，以及（3）当暴露于电磁辐射（EMR）时回收形状变形的至少一部分， 能源。 形状可变形材料可以有利地是薄膜，纤维，细丝，股线，无纺布和预成型元件的形式。 本发明的形状可变形材料可以用于形成既是一次性又可重复使用的产品。 更具体地，本发明的形状可变形材料可用于生产诸如一次性尿布，训练裤，失禁产品和女性护理产品的产品。
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24.发明申请METHODS OF MAKING BIODEGRADABLE FILMS HAVING ENHANCED DUCTILITY AND BREATHABILITY 审中-公开具有增强粘稠度和可穿透性的生物可降膜的方法
公开(公告)号：WO02085970A3
公开(公告)日：2003-03-13
申请号：PCT/US0212691
申请日：2002-04-18
Applicant: KIMBERLY CLARK CO
Inventor： TOPOLKARAEV VASILY A , SOERENS DAVE ALLEN
CPC classification number: C08L67/04 , A61L15/225 , A61L15/62 , C08J5/18 , C08J2300/16 , C08J2367/04 , C08L67/02 , C08L29/00 , C08L71/00
Abstract: The present invention is directed to methods of making biodegradable films and biodegradable precursor films having enhanced breathability and ductility. The method includes blending a water soluble polymer and a biodegradable polymer to form a blended polymer mixture. The biodegradable polymer is preferably a biodegradable aliphatic polyester, and the water-soluble polymer is preferably polyethylene oxide and/or polyethylene glycol. The blended polymer mixture is formed into a precursor film. The precursor film is further processed to form a breathable biodegradable film.
Abstract translation: 本发明涉及制造具有增强的透气性和延展性的可生物降解的薄膜和可生物降解的前体薄膜的方法。 该方法包括混合水溶性聚合物和可生物降解的聚合物以形成混合的聚合物混合物。 生物降解性聚合物优选为生物降解性脂肪族聚酯，优选水溶性聚合物为聚环氧乙烷和/或聚乙二醇。 混合的聚合物混合物形成前体膜。 进一步处理前体膜以形成透气的生物可降解膜。
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25.发明公开TECHNIQUE FOR SELECTIVELY CONTROLLING THE POROSITY OF A POLYMERIC MATERIAL 审中-公开VERFAHREN ZUR SELEKTIVEN STEUERUNG DERPOROSITÄTEINES POLYMERMATERIALS
公开(公告)号：EP3030607A4
公开(公告)日：2017-03-22
申请号：EP14835399
申请日：2014-06-06
Applicant: KIMBERLY CLARK CO
Inventor： TOPOLKARAEV VASILY A , MCENEANY RYAN J , SCHOLL NEIL T
CPC classification number: C08J9/0061 , B29C55/005 , B29K2105/04 , B29K2105/16 , C08J5/18 , C08J9/36 , C08J2300/22 , C08J2367/04 , C08J2423/08 , C08J2423/16
Abstract: A method for selectively controlling the degree of porosity in a polymeric material is provided. The material is formed from a thermoplastic composition containing a microinclusion additive and nanoinclusion additive that are dispersed within a continuous phase of a matrix polymer in the form of discrete domains. At least a portion of the polymeric material is strained so that a porous network is formed therein, Further, at least a portion of the strained polymeric material is heat treated so that it exhibits a Sower pore volume than the material prior to heat treatment, in this manner, the polymeric material can exhibit a high degree of initial flexibility, but this flexibility can be selectively reduced when desired.
Abstract translation: 提供了一种用于选择性地控制聚合物材料中孔隙率的方法。 该材料由含有微离子添加剂和纳米结合添加剂的热塑性组合物形成，其分散在离散区域形式的基质聚合物的连续相中。 聚合物材料的至少一部分被应变以便在其中形成多孔网状物。此外，将应变聚合物材料的至少一部分进行热处理，使得其在热处理之前显示出比材料更低的Sower孔体积， 以这种方式，聚合物材料可以表现出高度的初始柔性，但是当需要时可以选择性地降低该柔性。
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Patent Agency Ranking
公开(公告)号：EP3008119A4
公开(公告)日：2017-02-01
申请号：EP14811402
申请日：2014-06-06
Applicant: KIMBERLY CLARK CO
Inventor： TOPOLKARAEV VASILY A , MCENEANY RYAN J , TOWER THEODORE T , BIGGS DAVID G , SCHOLL NEIL T , EBY THOMAS A , CARRILLO ANTONIO J
CPC classification number: C08J9/0061 , C08J3/203 , C08J5/18 , C08J2323/12 , C08J2367/04 , C08J2423/08 , C08J2423/16 , C08J2467/04 , C08L23/12 , C08L67/04 , C08L23/0884
Abstract: A polymeric material having a multimodal pore size distribution is provided. The material is formed by applying a stress to a thermoplastic composition that contains first and second inclusion additives dispersed within a continuous phase that includes a matrix polymer. Through the use of particular types of inclusion additives and careful control over the manner in which such additives are dispersed within the polymer matrix, the present inventors have discovered that a unique, multimodal porous structure can be achieved.
Abstract translation: 提供具有多峰孔径分布的聚合物材料。 通过向包含分散在包括基质聚合物的连续相中的第一和第二夹杂物添加剂的热塑性组合物施加应力来形成材料。 通过使用特定类型的包合物添加剂并仔细控制这些添加剂分散在聚合物基体内的方式，本发明人已经发现可以实现独特的多峰多孔结构。
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公开(公告)号：EP2812395A4
公开(公告)日：2015-09-30
申请号：EP13746155
申请日：2013-01-28
Applicant: KIMBERLY CLARK CO
Inventor： SCHOLL NEIL T , MCENEANY RYAN J , EBY TOM , TOPOLKARAEV VASILY A
CPC classification number: C08L67/04 , C08L23/02 , C08L23/0815 , C08L23/10 , C08L33/00 , C08L63/00 , C08L67/00 , C08L71/00 , C08L2205/02 , C08L2205/03 , C08L2207/04 , C08L23/08 , C08L23/16
Abstract: A thermoplastic composition that contains a rigid renewable polyester and has a voided structure and low density is provided. To achieve such a structure, the renewable polyester is blended with a polymeric toughening additive to form a precursor material in which the toughening additive can be dispersed as discrete physical domains within a continuous matrix of the renewable polyester. The precursor material is thereafter stretched or drawn at a temperature below the glass transition temperature of the polyester (i.e., “cold drawn”). This creates a network of voids located adjacent to the discrete domains, which as a result of their proximal location, can form a bridge between the boundaries of the voids and act as internal structural “hinges” that help stabilize the network and increase its ability to dissipate energy. The present inventors have also discovered that the voids can be distributed in a substantially homogeneous fashion throughout the composition.
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公开(公告)号：EP2794837A4
公开(公告)日：2015-05-27
申请号：EP12860698
申请日：2012-11-08
Applicant: KIMBERLY CLARK CO
Inventor： TOPOLKARAEV VASILY A , SCHOLL NEIL T , KIM YOUNGSOOK , KOENIG DAVID W , LEE JAEHONG
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29.发明授权
公开(公告)号：EP2648523B1
公开(公告)日：2017-06-21
申请号：EP11846697
申请日：2011-10-31
Applicant: KIMBERLY CLARK CO
Inventor： WANG JAMES H , SHI BO , LEE JAEHONG , TOPOLKARAEV VASILY A , SCHOLL NEIL T , KIM YOUNGSOOK
CPC classification number: A01N31/08 , A01N65/00 , B29B7/10 , B29B7/38 , B29B9/06 , B29B9/12 , B29B9/16 , B29C47/00 , B29C47/6087 , A01N25/10 , A01N25/12 , A01N25/28 , A01N25/34 , A01N2300/00 , A01N65/08 , A01N65/20 , A01N65/24 , A01N65/28 , A01N65/38
Abstract: A method for forming a composition that includes mixing an antimicrobially active botanical oil (e.g., thymol, carvacrol, etc.) and a modified starch polymer within a melt blending device (e.g., extruder) is provided. Unlike the problems associated with proteins, the use of starch polymers allows for a greater degree of flexibility in the processing conditions and is still able to achieve good properties in the resulting composition. The present inventors have also discovered that a plasticizer may be employed to facilitate melt processing of the starch, as well as to enhance the ability of the botanical oil to flow into the internal structure of the starch where it can be retained in a stable manner. The composition is also typically generally free of solvents. In this manner, the starch will not generally disperse before use and prematurely release the botanical oil. Due to the water sensitivity of the modified starch, however, it may be subsequently dispersed by moisture when it is desired to release the botanical oil.
Abstract translation: 提供了一种形成组合物的方法，该组合物包括在熔体共混装置（例如挤出机）内混合抗微生物活性植物油（例如百里酚，香芹酚等）和改性淀粉聚合物。 与蛋白质相关的问题不同，淀粉聚合物的使用允许在加工条件下具有更大程度的灵活性并且仍然能够在所得组合物中实现良好的性质。 本发明人还发现，可以使用增塑剂来促进淀粉的熔融加工，以及增强植物油流入淀粉的内部结构的能力，在淀粉的内部结构中可以以稳定的方式保留淀粉。 该组合物通常也通常不含溶剂。 以这种方式，淀粉在使用前通常不会分散并过早释放植物油。 然而，由于改性淀粉对水的敏感性，当需要释放植物油时，它可能随后通过水分散。
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公开(公告)号：EP3030606A4
公开(公告)日：2017-03-22
申请号：EP14834572
申请日：2014-06-06
Applicant: KIMBERLY CLARK CO
Inventor： TOPOLKARAEV VASILY A , MCENEANY RYAN J , SCHOLL NEIL T , MLEZIVA MARK M
CPC classification number: C08J9/35 , B29C44/04 , B29C44/22 , B29C44/3415 , B29K2067/046 , B29K2105/16 , B29K2105/256 , B29K2423/08 , B29K2423/14 , B29L2007/002 , B29L2007/008 , B32B27/12 , C08J3/201 , C08J3/226 , C08J5/18 , C08J2367/04 , C08J2423/12 , C08J2423/14 , C08J2433/14 , C08K9/08 , C08L23/0884 , C08L23/10 , C08L23/16 , C08L67/04
Abstract: A polymeric material having anisotropic properties, such as mechanical properties (e.g., modulus of elasticity), thermal properties, barrier properties (e.g., breathability), and so forth, is provided. The anisotropic properties can be achieved for a single, monolithic polymeric material through selective control over the manner in which the material is formed. For example, one or more zones of the polymeric material can be strained to create a unique network of pores within the strained zone(s). However, zones of the polymeric material that are not subjected to the same degree of deformational strain will not have the same pore volume, and in some cases, may even lack a porous network altogether.
Abstract translation: 提供具有各向异性特性的聚合材料，例如机械性能（例如弹性模量），热性能，阻隔性能（例如透气性）等。 通过选择性地控制形成材料的方式，可以为单一的整体聚合材料实现各向异性特性。 例如，聚合物材料的一个或多个区域可以被应变以在应变区域内形成独特的孔网。 然而，未经受相同程度的变形应变的聚合物材料的区域将不具有相同的孔体积，并且在一些情况下，甚至可能完全缺少多孔网络。
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