公开(公告)号：EP3409777A1

公开(公告)日：2018-12-05

申请号：EP18171330.6

申请日：2011-11-28

Applicant: Life Technologies AS

Inventor： ELLIS, Darren James ,  HOFSLOKKEN KJUS, Nini ,  FONNUM, Geir

IPC: C12N15/10

CPC classification number: C12Q1/6806 ,  C12N15/1006 ,  C12N15/1013

Abstract: A method for processing a nucleic acid, in which the nucleic acid is exposed to an aqueous medium which includes a polyol in sufficient proportion for at least a portion of the nucleic acid to enter or remain in an extra-solution phase. Thus, a polyol may be used to bind a nucleic acid which is in solution to a solid support or to wash a nucleic acid on a solid support whilst maintaining it on the support.

公开(公告)号：EP2993232B1

公开(公告)日：2018-05-16

申请号：EP15179788.3

申请日：2011-11-28

Applicant: Life Technologies AS

Inventor： ELLIS, Darren James ,  HOFSLOKKEN KJUS, Nini ,  FONNUM, Geir

IPC: C12N15/10

CPC classification number: C12Q1/6806 ,  C12N15/1006 ,  C12N15/1013

Abstract: A method for processing a nucleic acid, in which the nucleic acid is exposed to an aqueous medium which includes a polyol in sufficient proportion for at least a portion of the nucleic acid to enter or remain in an extra-solution phase. Thus, a polyol may be used to bind a nucleic acid which is in solution to a solid support or to wash a nucleic acid on a solid support whilst maintaining it on the support.

公开(公告)号：EP3317314A1

公开(公告)日：2018-05-09

申请号：EP16741201.4

申请日：2016-07-01

Applicant: Life Technologies Corporation ,  Life Technologies AS

Inventor： FONNUM, Geir ,  MENCHEN, Steven, M. ,  GOKMEN, Talha, M. ,  LUNDBERG, Pontus ,  THWAR, Prasanna Krishnan ,  LUI, Alfred ,  LU, Lily ,  HINZ, Wolfgang ,  HUSABOE, Lene ,  BREIVOLD, Elisabeth ,  MOLTEBERG, Astrid, Evenroed ,  LARSEN, Synne

IPC: C08F220/58 ,  C08F8/12

Abstract: A polymer substrate, such as a polymer particle, is formed from a carboxyl functional monomer. In an example, the carboxyl functional monomer has a protection group in place of the OH of the carboxyl group. Once the monomer is polymerized, such a protection group can be removed, providing a polymer network with carboxyl functional sites. Such sites can be used to attach other functionality to the polymer substrate.

公开(公告)号：EP2424901B1

公开(公告)日：2017-05-31

申请号：EP10718956.5

申请日：2010-04-29

Applicant: Life Technologies AS

Inventor： MODAHL, Grete Irene ,  FONNUM, Geir ,  MOLTEBERG, Astrid ,  LIEN, Silje ,  KJUS, Nini Hofslokken

IPC: C08F2/22

CPC classification number: C08F2/22 ,  C08F8/30 ,  C08F12/08 ,  C08F212/36 ,  C08F257/02 ,  C08F2800/20 ,  C08J3/128 ,  C08J9/18 ,  C08J9/20 ,  C08J2325/08 ,  C12N11/08 ,  Y10T428/2982 ,  Y10T428/2991 ,  Y10T428/2998 ,  C08F212/08

Abstract: This invention relates to monodisperse cross-linked polymer particles, comprising particles with a substantially smooth outer surface and an average diameter of less than 1 μm, wherein the particles are solid or porous, and wherein the coefficient of variation (CV) % of the particles, when measured by CPS disk centrifugation analysis, is less than 15%. These monodisperse cross-linked polymer particles may comprise magnetic material and are useful in various application. This invention also relates to monodisperse polymer particles for use as seed particles in the Ugelstad process.

Abstract translation: 本发明涉及单分散交联聚合物颗粒，其包含具有基本光滑的外表面和平均直径小于1μm的颗粒，其中颗粒是固体或多孔的，并且其中颗粒的变异系数（CV）％ 当通过CPS盘式离心分析测量时，小于15％。 这些单分散交联聚合物颗粒可以包含磁性材料并且可用于各种应用。 本发明还涉及在Ugelstad方法中用作种子颗粒的单分散聚合物颗粒。

公开(公告)号：EP2038320B1

公开(公告)日：2014-03-12

申请号：EP07812526.7

申请日：2007-06-29

Applicant: Life Technologies AS

Inventor： FONNUM, Geir ,  LILJEROTH, Lise

IPC: C08F293/00 ,  C08F287/00 ,  C08L53/00 ,  C09D153/00

CPC classification number: C08F293/00 ,  C08F287/00 ,  C08F292/00 ,  C08F293/005 ,  C08F2438/01 ,  C08L53/005 ,  C09D153/005 ,  C08L2666/02

Abstract: Polymer particles having a multi-block vinylic polymer attached to their surface are disposed. The particles can be used in a variety of purification and detection methods.