公开(公告)号：JP2010127816A

公开(公告)日：2010-06-10

申请号：JP2008304128

申请日：2008-11-28

Applicant: Panasonic Corp ,  パナソニック株式会社

Inventor： YAMADA RYOSUKE ,  AGAWA MASAHIRO ,  MIYOSHI KOJI ,  MURAKAMI KENJI ,  KUROKAWA HIDEYUKI ,  TANIDA TAKAHIKO

IPC: G01N21/27

Abstract: PROBLEM TO BE SOLVED: To perform correction in correspondence with a specimen concentration, in an analysis method and an analyzer for acquiring specimen concentration information by receiving light from the specimen by an image sensor through an optical system such as an optical filter.
SOLUTION: A brightness value of light from the specimen on a test piece is calculated beforehand, and a correction coefficient for allowing a brightness distribution in each concentration to agree with a brightness distribution of a reference concentration is calculated, and each correction coefficient is linearly approximated. A correction function for filter incident angle dependency is calculated based on the brightness distribution of the reference concentration. The brightness of the specimen which is a measuring object on the test piece is corrected by using the correction function, and concentration information is calculated therefrom, and a concentration correction coefficient is acquired on reference to a prior approximate straight line. The concentration correction coefficient α is integrated on the correction function gm(r) for the filter incident angle dependency corresponding to the reference concentration (b), and the brightness (a) of the specimen which is the measuring object is corrected thereby (c). The concentration information of the specimen which is the measuring object is acquired by using the corrected brightness.
COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 要解决的问题：根据样本浓度进行校正，在分析方法中和通过诸如滤光器的光学系统通过从图像传感器接收来自样本的光来获取样本浓度信息的分析器。 ＆lt; P＆gt;＆lt;解决方案＆gt;预先计算来自试样上的试样的光的亮度值，并计算使各浓度的亮度分布与参考浓度的亮度分布一致的校正系数，并且每个校正系数 线性近似。 基于参考浓度的亮度分布计算滤波器入射角依赖性的校正函数。 通过使用校正函数来校正作为测试件上的测量对象的样本的亮度，并且从其计算浓度信息，并且参考先前的近似直线获取浓度校正系数。 对于与基准浓度（b）相对应的滤波器入射角依赖性，将浓度校正系数α积分在校正函数gm（r）上，并且由此校正作为测量对象的样本的亮度（a） 。 通过使用校正亮度获取作为测量对象的样本的浓度信息。 版权所有（C）2010，JPO＆INPIT

公开(公告)号：JP2010107453A

公开(公告)日：2010-05-13

申请号：JP2008281854

申请日：2008-10-31

Applicant: Panasonic Corp ,  パナソニック株式会社

Inventor： AGAWA MASAHIRO ,  MIYOSHI KOJI ,  MURAKAMI KENJI ,  KUROKAWA HIDEYUKI ,  TANIDA TAKAHIKO ,  YAMADA RYOSUKE

IPC: G01N21/01 ,  G01N21/78

Abstract: PROBLEM TO BE SOLVED: To provide a measuring instrument that is unlikely to cause position gap or tilting of a biosensor.
SOLUTION: The measuring instrument 110 uses a biosensor to perform chromatography, with the biosensor being a testpiece administering chemical treatment on a measurement object specimen. A mounting section 119, having a space where the biosensor is inserted in the longitudinal direction thereof, includes a first positioning mechanism 155, which presses and positions the biosensor against the side surface of a groove 151 in the mounting section 119 along the lateral direction of the biosensor; and a second positioning mechanism 156, which presses and positions the biosensor against the back surface of the edge 152b of the mounting section 119, along the thickness direction of the biosensor.
COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 要解决的问题：提供不太可能导致生物传感器的位置间隙或倾斜的测量仪器。

解决方案：测量仪器110使用生物传感器进行色谱，其中生物传感器是对测量对象样品进行化学处理的试验片。 具有生物传感器沿其长度方向插入的空间的安装部119包括：第一定位机构155，其将生物传感器按压并定位在安装部119的槽151的侧面， 生物传感器 以及第二定位机构156，其沿生物传感器的厚度方向按压并定位生物传感器抵靠安装部119的边缘152b的背面。 版权所有（C）2010，JPO＆INPIT

公开(公告)号：JP2009175017A

公开(公告)日：2009-08-06

申请号：JP2008014328

申请日：2008-01-25

Applicant: Panasonic Corp ,  パナソニック株式会社

Inventor： YAMADA RYOSUKE ,  AGAWA MASAHIRO

IPC: G01N21/27

Abstract: PROBLEM TO BE SOLVED: To provide an analytical method and an analyzer capable of reducing measurement errors due to the dependency of optical filters on the angle of incidence.
SOLUTION: Light from a specimen 2 carried by a test strip 3 is passed through an optical system having an optical filter 6 and received by an image sensor 7 provided with a plurality of pixels to acquire concentration information of the specimen in the analytical method. The angle θ of the filter incidence incident onto the optical filter 6 of the light which forms an image in the pixels A is computed. The amount of shift of the filter band of the optical filter 6 corresponding to the angle θ of the filter incidence is acquired to acquire a correction coefficient corresponding to the amount of shift. The correction coefficient is used to correct luminance. Concentration information of the specimen 2 is acquired on the basis of this corrected luminance value. Since it is possible to reduce measurement errors due to the dependency of the optical filter 6 on the angle of incidence by this analytical method, measurement accuracy and reliability at the time of analyzing the specimen 2 are improved.
COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供一种能够减少由于滤光器对入射角的依赖性引起的测量误差的分析方法和分析仪。 解决方案：由试片3承载的样本2的光通过具有滤光器6的光学系统，并由具有多个像素的图像传感器7接收，以获得分析中的样本的浓度信息 方法。 计算入射到形成像素A中的图像的光的滤光器6上的滤光器入射角度θ。 获取与滤波器入射角度θ对应的滤光器6的滤波器带的偏移量，以获得与偏移量相对应的校正系数。 校正系数用于校正亮度。 基于该修正后的亮度值，取得样本2的浓度信息。 由于可以通过该分析方法减少由于滤光器6的依赖性导致的测量误差，因此提高了分析试样2时的测量精度和可靠性。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2009098080A

公开(公告)日：2009-05-07

申请号：JP2007271881

申请日：2007-10-19

Applicant: Panasonic Corp ,  パナソニック株式会社

Inventor： KUROKAWA HIDEYUKI ,  AGAWA MASAHIRO ,  TANIDA TAKAHIKO ,  MATSUDA YOKO ,  YAMADA RYOSUKE

IPC: G01N33/543 ,  G01N21/78

Abstract: PROBLEM TO BE SOLVED: To provide an immunochromatographic measurement apparatus for accurately obtaining the degree of coloration, and determining a concentration of to-be-measured component if dust other than the to-be-measured component and a residual marker material remain in an immobilized reagent provided on a chromatographic specimen.
SOLUTION: The immunochromatographic measurement apparatus includes: a coloration reading means 1 for optically reading a plurality of immobilized reagent sections on the chromatographic specimen at a predetermined sampling interval, and generating reading data; a degree-of-coloration calculating means 2 for calculating the degree of coloration in each immobilized reagent section from the reading data; a degree-of-coloration storing means 3 for storing a temporal change in the degree of coloration in each immobilized reagent section as a degree-of-coloration data sequence; a stationary value detecting means 4 for obtaining the stationary degree of coloration from the degree-of-coloration data sequence of each immobilized reagent section; and a concentration determining means 5 for determining the concentration of the to-be-measured component within a to-be-inspected liquid by using a combination of the stationary degree of coloration in the immobilized reagent sections.
COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供用于准确获得着色程度的免疫色谱测量装置，以及如果除了被测量组分之外的灰尘和剩余标记物质残留，则确定待测量组分的浓度 在提供在色谱样品上的固定化试剂中。 解决方案：免疫色谱测量装置包括：着色读取装置1，用于以预定的采样间隔光学读取色谱试样上的多个固定化试剂部分，并产生读数据; 着色度计算装置2，用于根据读取数据计算每个固定化试剂部分中的着色程度; 着色度存储装置3，用于将每个固定化试剂部分中的着色程度的时间变化存储为着色度数据序列; 稳定值检测装置4，用于根据每个固定化试剂部分的着色数据序列获得稳定的着色度; 以及浓度确定装置5，用于通过使用固定化试剂部分中的稳定着色程度的组合来确定待检查液体中被测量部件的浓度。 版权所有（C）2009，JPO＆INPIT