公开(公告)号：AU2002323122B2

公开(公告)日：2006-09-14

申请号：AU2002323122

申请日：2002-08-13

Applicant: PHARMACIA CORP

Inventor： PHILLION DENNIS P

IPC: C07C211/24 ,  C07C17/16 ,  C07C17/18 ,  C07C19/01 ,  C07C23/08 ,  C07C51/56 ,  C07C53/40 ,  C07C53/42 ,  C07C63/10 ,  C07C65/03 ,  C07C65/05 ,  C07C201/14 ,  C07C205/57 ,  C07C209/00 ,  C07C209/74 ,  C07C211/27 ,  C07C211/29 ,  C07C269/06 ,  C07C271/22 ,  C07C303/02 ,  C07C303/38 ,  C07C309/86 ,  C07C311/16 ,  C07D207/34 ,  C07D207/416 ,  C07D233/90 ,  C07D307/68 ,  C07D309/10 ,  C07D403/14 ,  C07F7/12 ,  C07F7/18 ,  C07F9/12 ,  C07F9/14 ,  C07F9/40 ,  C07F9/42 ,  C07F9/44 ,  C08F8/30

Abstract: The present invention describes immobilized haloenamine reagents, immobilized tertiary amides, methods for their preparation, and methods of use.

公开(公告)号：BR0317430A

公开(公告)日：2005-10-25

申请号：BR0317430

申请日：2003-12-19

Applicant: PHARMACIA CORP

Inventor： ANDERSON DAVID R ,  MAHONEY MATTHEW W ,  PHILLION DENNIS P ,  ROGERS THOMAS E ,  MEYERS MARVIN J ,  PODA GENNADIY ,  HEDGE SHRIDHAR G ,  SINGH MEGH ,  REITZ DAVID B ,  WU KUN K ,  BUCHLER INGRID P ,  XIE JIN ,  VERNIER WILLIAM F

IPC: A61K31/415 ,  A61K31/4439 ,  A61K31/519 ,  C07D401/04 ,  C07D471/04 ,  C07D471/14 ,  C07D487/04 ,  C07D513/04 ,  C07D519/00 ,  C07D471/06

Abstract: Compounds are described which inhibit mitogen activated protein kinase-activated protein kinase-2 (MK-2). Methods of making such compounds are described, as well as a method of using them for the inhibition of MK-2, and for the prevention or treatment of a disease or disorder that is mediated by TNFalpha, where the method involves administering to the subject an MK-2 inhibiting compound of the present invention. Pharmaceutical compositions and kits which contain the present MK-2 inhibiting compounds are also described.

公开(公告)号：ZA200401586B

公开(公告)日：2005-03-10

申请号：ZA200401586

申请日：2004-02-26

Applicant: PHARMACIA CORP

Inventor： PHILLION DENNIS P

IPC: C07C20060101 ,  C07D20060101 ,  C07C

公开(公告)号：ZA200401588B

公开(公告)日：2005-02-25

申请号：ZA200401588

申请日：2002-08-30

Applicant: PHARMACIA CORP

Inventor： PHILLION DENNIS P

IPC: C07C20060101 ,  C07D20060101 ,  C07D

公开(公告)号：BR0212393A

公开(公告)日：2004-08-17

申请号：BR0212393

申请日：2002-08-30

Applicant: PHARMACIA CORP

Inventor： PHILLION DENNIS P

IPC: C07C17/16 ,  C07C17/18 ,  C07C19/01 ,  C07C23/08 ,  C07C51/56 ,  C07C53/40 ,  C07C53/42 ,  C07C63/10 ,  C07C65/03 ,  C07C65/05 ,  C07C201/14 ,  C07C205/57 ,  C07C209/00 ,  C07C209/74 ,  C07C211/24 ,  C07C211/29 ,  C07C269/06 ,  C07C271/22 ,  C07C303/02 ,  C07C303/38 ,  C07C309/86 ,  C07C311/16 ,  C07D207/34 ,  C07D207/416 ,  C07D233/90 ,  C07D307/68 ,  C07D309/10 ,  C07D403/14 ,  C07F7/12 ,  C07F7/18 ,  C07F9/12 ,  C07F9/14 ,  C07F9/40 ,  C07F9/42 ,  C07F9/44 ,  C08F8/30

Abstract: The present invention describes immobilized haloenamine reagents, immobilized tertiary amides, methods for their preparation, and methods of use.