公开(公告)号：WO2006018817A3

公开(公告)日：2006-06-15

申请号：PCT/IB2005052714

申请日：2005-08-17

Applicant: KONINKL PHILIPS ELECTRONICS NV ,  PHILIPS INTELLECTUAL PROPERTY ,  GRASS MICHAEL ,  RASCHE VOLKER

Inventor： GRASS MICHAEL ,  RASCHE VOLKER

IPC: A61B6/03

CPC classification number: A61B6/481 ,  A61B6/032 ,  A61B6/4035 ,  A61B6/405 ,  A61B6/4441 ,  A61B6/463 ,  A61B6/466 ,  A61B6/482 ,  A61B6/504

Abstract: The invention relates to a method and an examination apparatus for the evaluation of X-ray projections (31-33, 41-43) that were generated with a rotational X-ray device (10) from different directions and with an energy level varying periodically from projection to projection. Said variation may for example be achieved by a continuously modulated tube voltage (V). Two different 3D-images (35, 45) may be reconstructed from the X-ray projections (31-33, 41-43) which belong to the different energy levels, and said 3D-images may then be compared voxel by voxel in order to segment structures (50) of interest due to contrast differences.

Abstract translation: 本发明涉及一种用于评估X射线投影（31-33,41-43）的方法和检查装置，所述X射线投影由旋转X射线装置（10）从不同方向产生并且能量水平周期性变化 从投影到投影。 所述变化例如可以通过连续调制的管电压（V）来实现。 可以根据属于不同能级的X射线投影（31-33,41-43）重建两个不同的3D图像（35,45），并且然后可以按照体素的顺序将所述3D图像与体素进行比较 由于对比度差异来分割感兴趣的结构（50）。

公开(公告)号：WO2004072903A3

公开(公告)日：2004-11-25

申请号：PCT/IB2004000261

申请日：2004-02-03

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  RASCHE VOLKER ,  MOVASSAGHI BABAK

Inventor： RASCHE VOLKER ,  MOVASSAGHI BABAK

IPC: G06T7/00 ,  G06T11/00 ,  G06T17/10

CPC classification number: G06T11/008 ,  G06T17/10 ,  G06T2211/404 ,  G06T2211/412

Abstract: The invention relates to a method for the 3D modeling of a three-dimensional tubular structure of an examination object from a number of 2D projection images (D) of the tubular structure (H) taken from different projection directions. In order to be able to implement such a method with considerably less user interaction while retaining the same degree of accuracy, the following steps are proposed according to the invention: a) reconstruction of a 3D image (B) from the 2D projection images (D), b) selection of at least one 3D central line point (MO) in the 3D image (B), said 3D central line point being located in the tubular structure (H), c) segmentation of other 3D central line points (M) of the tubular structure (H) in the 3D image (B), d) forward projection of the 3D central line points (M), which have been segmented in the 3D image (B), into the 2D projection images (D'), e) determination of border points of the tubular structure (H) in the 2D projection images (D') on the basis of the 3D central line points (Z) that have been projected in, and f) back-projection of the border points from the 2D projection images (D') into the 3D image (B).

Abstract translation: 本发明涉及从不同投影方向拍摄的管状结构（H）的多个2D投影图像（D）对检查对象的三维管状结构进行3D建模的方法。 为了能够以相当少的用户交互实现这种方法，同时保持相同的准确度，根据本发明提出以下步骤：a）从2D投影图像（D）重建3D图像（B） ），b）在3D图像（B）中选择至少一个3D中心线点（MO），所述3D中心线点位于管状结构（H）中，c）其他3D中心线点（M ）的三维图像（B）中的管状结构（H），d）已经在3D图像（B）中分割的3D中心线点（M）向2D投影图像（D' ），e）基于投影到的3D中心线点（Z），确定2D投影图像（D'）中的管状结构（H）的边界点，以及f） 从2D投影图像（D'）到3D图像（B）的边界点。

公开(公告)号：WO2007138526A2

公开(公告)日：2007-12-06

申请号：PCT/IB2007051915

申请日：2007-05-21

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  SCHAEFER DIRK ,  ENGLER ANDREAS ,  MOVASSAGHI BABAK ,  RASCHE VOLKER ,  GRASS MICHAEL

Inventor： SCHAEFER DIRK ,  ENGLER ANDREAS ,  MOVASSAGHI BABAK ,  RASCHE VOLKER ,  GRASS MICHAEL

CPC classification number: A61B6/504 ,  A61B6/032 ,  A61B6/4085 ,  A61B6/481 ,  A61B6/5288 ,  A61B6/541 ,  G06T3/0037 ,  G06T7/20 ,  G06T2207/10081 ,  G06T2207/20016 ,  G06T2207/30101

Abstract: In three-dimensional rotational x-ray coronary imaging problems may arise when estimating the motion of small vessels. According to an exemplary embodiment of the present invention, an examination apparatus is provided which is adapted for performing a hierarchical motion estimation by global affine transformation for every heart phase, followed by vessel branch selective affine and non-affine transformations. This may provide for an improved image quality.

Abstract translation: 在估计小血管运动时可能出现三维旋转X射线冠状动脉成像问题。 根据本发明的示例性实施例，提供了一种检查装置，其适用于通过用于每个心脏相的全局仿射变换执行分层运动估计，随后是血管分支选择仿射和非仿射变换。 这可以提供改进的图像质量。

公开(公告)号：WO2005020155A8

公开(公告)日：2006-06-01

申请号：PCT/IB2004051428

申请日：2004-08-09

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  MOVASSAGHI BABAK ,  RASCHE VOLKER

Inventor： MOVASSAGHI BABAK ,  RASCHE VOLKER

IPC: G06T7/00 ,  G06T11/00

CPC classification number: G06K9/20 ,  G06K2009/00932 ,  G06K2209/05 ,  G06T7/55 ,  G06T2207/30101

Abstract: The invention relates to a method for the reconstruction of a three-dimensional model of a vascular tree from two-dimensional X-ray projection images (A, B, C) that are taken from different spatial directions. On a first projection image (A) at least one reference point (C A ) is specified. The gray-value profiles along the epipolar lines (E B , E C ) for said reference point (C A ) in other projection images (B, C) are then projected on the projection line (L) of the reference point (C A ) and added there punctiformly to form a sum profile (S). The sum profile (S) has an extreme, for example, a gray-value minimum, at the position of the space point (C 3D ) belonging to the reference point (C A ). In this way, it is possible to reconstruct semiautomatically a vascular tree from X-ray projections.

Abstract translation: 本发明涉及从不同空间方向拍摄的二维X射线投影图像（A，B，C）重建血管树的三维模型的方法。 在第一投影图像（A）上指定至少一个参考点（C SUB> A ）。 在其他投影图像中的用于所述参考点（C SUB）的沿着线极线（E SUB B，E C C）的灰度值分布（ B，C）然后投影在参考点（C SUB）上的投影线（L）上，并且以点一点的形式加到其上，形成总和曲线（S）。 总和简档（S）在属于参考点的空间点（C 3D 3D）的位置处具有极端的例如灰度值最小值（C A ）。 以这种方式，可以从X射线投影半自动重建血管树。

公开(公告)号：WO2004093684A8

公开(公告)日：2006-03-02

申请号：PCT/IB2004050476

申请日：2004-04-21

Applicant: PHILIPS INTELLECTUAL PROPERTY ,  KONINKL PHILIPS ELECTRONICS NV ,  SCHMITT HOLGER ,  GRASS MICHAEL ,  RASCHE VOLKER

Inventor： SCHMITT HOLGER ,  GRASS MICHAEL ,  RASCHE VOLKER

IPC: A61B6/00

CPC classification number: A61B6/481 ,  A61B6/4441 ,  A61B6/504

Abstract: The invention relates to an X-ray photographic apparatus for imaging the blood flow in the coronary vessel tree of a patient. According to the invention, a first series (1) of X-ray projection images of the coronary tree in various phases of the heart cycle is recorded, at the same time as the ECG (2) of the patient is taken. The three-dimensional structure of the vessel tree in the various phases of the heart cycle is then reconstructed by means of suitable programming means of the computerised portion (17) of the claimed apparatus. A second series (6) of X-ray projection images is recorded while a contrast agent is administered, again at the same time as the ECG (7) is taken. In order to determine the time-dependent contrast agent concentration within the reconstructed three-dimensional structure of the vessel tree, the invention proposes locating local image regions which correspond to individual vessel segments (5, 8) within the X-ray projection images in the second series (6), according to the positions in space of the vessel segments (5, 8) in the relevant phase of the heart cycle. The contrast agent concentration in the area of the vessel segments (5, 8) is then determined by evaluation of X-ray absorption in the thus located local image regions.

Abstract translation: 本发明涉及一种X射线成像装置用于在患者的冠状血管树中的血液流动的可视化。 它是按照本发明采取的，在心动周期的不同阶段的血管树的X射线投影图像中的第一组（1）用ECG的同时记录（2）病人的。 然后，通过计算机的合适的程序的控制手段根据本发明的血管树的三维结构在心动周期的不同阶段的重构装置的装置（17）。 X射线投影图像的第二组（6）的造影剂的给药过程中被记录时，再次记录ECG（7）。 本发明提出以确定所述血管树中，每个容器的段的重构的三维结构内依赖于时间的造影剂浓度（5,8）与（6）对应于所述血管段的在相应的空间位置（8 5），第二组的x射线投影图像中的局部图像区域相关联的 发现心动周期的相位。 然后造影剂浓度的血管段的区域中的确定（5,8）由所述发现局部图像区域内评估Röntgenabsorbtion。