Abstract:
Methods and devices for isolating nucleic acids from a mixture containing such nucleic acids and extraneous matter are provided. In one embodiment, the method of the invention comprises passing the mixture through a glass frit under conditions effective to separate the nucleic acids from the extraneous matter. In a more specific embodiment, the glass frit is a sintered glass frit.
Abstract:
Methods and devices for isolating nucleic acids from a mixture containing such nucleic acids and extraneous matter are provided. In one embodiment, the method of the invention comprises passing the mixture through a glass frit under conditions effective to separate the nucleic acids from the extraneous matter. In a more specific embodiment, the glass frit is a sintered glass fit.
Abstract:
This invention relates to advanced composite filtration media comprising a functional filtration component and a matrix component, and methods for preparing and using same. More particularly, this invention pertains to advanced composite filtration media and advanced composite filtration media products comprised of a functional filtration component, such as a biogenic silica product (e.g., diatomite), a natural glass product (e.g., expanded perlite), or a natural or synthetic crystalline mineral (e.g., titanium dioxide), which is thermally sintered to a matrix component, such as an engineering polymer (e.g., glasses, natural or synthetic crystalline minerals, thermoplastics, and metals) or a suitable natural material (e.g., rice hull ash, sponge spicules) that has a softening temperature below that of the functional filtration component. This invention also relates to advanced composite media and advanced composite media products, generally, which are also useful in non-filtration applications.
Abstract:
A device and method for permitting the separation of plasma or serum from whole blood. The device comprises a matrix of hydrophilic sintered porous material to which at least one red blood cell agglutinating agent has been applied. According to a first method of using the device, a sample of whole blood is applied to a first end of the matrix and the red blood cells within the sample come in contact with the agglutinating agents present in the matrix. The blood cells agglutinate, and are entrapped in the interstices of the matrix, while substantially blood-cell-free serum or plasma accumulates near the outlet of the device. A filter means in liquid receiving relationship with the matrix functions to wick the serum of plasma from the matrix.According to an alternative aspect of the invention, a filter means in liquid receiving relationship with the outlet of the matrix functions to retain any blood cells which pass through the matrix as the filter means wicks the plasma or serum from the matrix. Additional agglutinating agents may be incorporated within the filter means to facilitate retention of blood cells which pass through the matrix.Another aspect of the present invention involves a device for the measurement of a serum or plasma sample, utilizing a matrix of sintered porous material, such as sintered glass, sintered steel, sintered ceramics, sintered plastics, and equivalents thereof. The matrix is characterized by a reproducible fluid uptake capacity proportional to the fixed dimensions of said matrix, a minimal reactivity with plasma or serum components, and a hydrophilic internal surface which enables the matrix to collect and retain a predetermined volume of sample for analysis.
Abstract:
Filter bodies are made by mixing borosilicate glass powder, potassium sulphate and 30% aqueous polyethylene glycol solution per kilogram of mixture. The mixture is filtered and dried and glass particles of a different size are mixed into the dried granulate. The resulting mixture is compressed at a pressure of 1000 bar to form blanks and sintered at about 860.degree. C. After cooling, the potassium sulphate is washed out of the blanks.
Abstract:
A filter membrane for filtering liquid food stuffs or hot gases and including at least one filter layer. The membrane is constituted by a sintered inorganic material comprising grains which are fixedly connected to one another and the average roughness of the surface of said filter layer over a distance along said surface equal to at least five times the average grain size is less than one fifth of the average grain size in the region in question.
Abstract:
A microbicidal filter system having superior drop pressure and low complexity is provided, as well as a method for producing the same. The system comprises a plurality of glass beads having pores formed therebetween for the flow of air therethrough. The sintered glass beads are coated in a transition metal oxide and water. An ultraviolet light source is used to cause a photocatalytic reaction between the transition metal oxide and water. Free hydroxyl radicals with microbicidal properties are produced. Urethane foam may be inserted between the glass beads before sintering in order to cause a bimodal pore size distribution, and particulates disposed on the glass beads may be added to alter surface activity.
Abstract:
A dimensionally stable permeable fluid treatment element, especially a filter element, suitable for the treatment of hot fluids, characterized by the following constituents: (a) inorganic solid particles with inner cavities, (b) a hardened water glass based binder, (c) whereby the solid particles forming the permeable fluid treatment element are held together by the binder.
Abstract:
Process for removing hydrocarbons from a body of water wherein the hydrocarbons are separated from the aqueous phase by selective permeation through a sintered porous filter surface-treated with at least one hydrophobic product, so as to collect the hydrocarbons and remove them from the water without using additional chemical products or products capable of absorbing the hydrocarbons. This allows the body of water to be remediated and at the same time recover the hydrocarbons spilled in a clean and substantially continuous manner. The filter preferably consists of a sintered inorganic material, such as for example a metallic material, a vitreous material, a ceramic material.
Abstract:
A composite structure includes a substrate with pores of a first mean pore size and a coating on at least one surface of that substrate. This coating has pores of a second mean pore size where the first mean pore size is equal to or greater than said second mean pore size. When the pore size of the coating is effective to capture particulate greater than 0.2 micron, the composite may be formed into a filter effective to remove microbes from a fluid medium. One method to form the porous coating on the substrate includes the steps of: (a) forming a suspension of sinterable particles in a carrier fluid and containing the suspension in a reservoir; (b) maintaining the suspension by agitation in the reservoir; (c) immersing the substrate in the reservoir; (c) applying a first coating of the suspension to the substrate; (d) removing the substrate with the applied first coating from the reservoir; and (e) sintering the sinterable particles to the substrate thereby forming a coated substrate.