Apparatus, System and Method for Purifying Nucleic Acids
    22.
    发明申请
    Apparatus, System and Method for Purifying Nucleic Acids 有权
    用于纯化核酸的装置,系统和方法

    公开(公告)号:US20100240882A1

    公开(公告)日:2010-09-23

    申请号:US12793218

    申请日:2010-06-03

    Abstract: Methods and devices for isolating nucleic acids from a mixture containing such nucleic acids and extraneous matter are provided. In one embodiment, the method of the invention comprises passing the mixture through a glass frit under conditions effective to separate the nucleic acids from the extraneous matter. In a more specific embodiment, the glass frit is a sintered glass fit.

    Abstract translation: 提供了从含有这种核酸和外来物质的混合物中分离核酸的方法和装置。 在一个实施方案中,本发明的方法包括在有效将核酸与外来物质分离的条件下使混合物通过玻璃料。 在更具体的实施例中,玻璃料是烧结玻璃。

    Advanced composite media
    23.
    发明授权
    Advanced composite media 失效
    高级复合介质

    公开(公告)号:US06524489B1

    公开(公告)日:2003-02-25

    申请号:US09110939

    申请日:1998-07-06

    Abstract: This invention relates to advanced composite filtration media comprising a functional filtration component and a matrix component, and methods for preparing and using same. More particularly, this invention pertains to advanced composite filtration media and advanced composite filtration media products comprised of a functional filtration component, such as a biogenic silica product (e.g., diatomite), a natural glass product (e.g., expanded perlite), or a natural or synthetic crystalline mineral (e.g., titanium dioxide), which is thermally sintered to a matrix component, such as an engineering polymer (e.g., glasses, natural or synthetic crystalline minerals, thermoplastics, and metals) or a suitable natural material (e.g., rice hull ash, sponge spicules) that has a softening temperature below that of the functional filtration component. This invention also relates to advanced composite media and advanced composite media products, generally, which are also useful in non-filtration applications.

    Abstract translation: 本发明涉及包含功能性过滤组分和基质组分的高级复合过滤介质及其制备和使用方法。 更具体地说,本发明涉及先进的复合过滤介质和由功能性过滤组分(例如生物二氧化硅产物(例如硅藻土)),天然玻璃制品(例如膨胀珍珠岩)或天然的二氧化硅 或热合烧结到基质组分的合成结晶矿物(例如二氧化钛),例如工程聚合物(例如玻璃,天然或合成结晶矿物,热塑性塑料和金属)或合适的天然材料(例如,米 软化温度低于功能性过滤组分的软化温度。 本发明还涉及高级复合介质和高级复合介质产品,通常也可用于非过滤应用。

    Devices and methods for the collection of a predetermined volume of
plasma or serum
    24.
    发明授权
    Devices and methods for the collection of a predetermined volume of plasma or serum 失效
    用于收集预定体积的血浆或血清的装置和方法

    公开(公告)号:US5064541A

    公开(公告)日:1991-11-12

    申请号:US499864

    申请日:1990-03-27

    Abstract: A device and method for permitting the separation of plasma or serum from whole blood. The device comprises a matrix of hydrophilic sintered porous material to which at least one red blood cell agglutinating agent has been applied. According to a first method of using the device, a sample of whole blood is applied to a first end of the matrix and the red blood cells within the sample come in contact with the agglutinating agents present in the matrix. The blood cells agglutinate, and are entrapped in the interstices of the matrix, while substantially blood-cell-free serum or plasma accumulates near the outlet of the device. A filter means in liquid receiving relationship with the matrix functions to wick the serum of plasma from the matrix.According to an alternative aspect of the invention, a filter means in liquid receiving relationship with the outlet of the matrix functions to retain any blood cells which pass through the matrix as the filter means wicks the plasma or serum from the matrix. Additional agglutinating agents may be incorporated within the filter means to facilitate retention of blood cells which pass through the matrix.Another aspect of the present invention involves a device for the measurement of a serum or plasma sample, utilizing a matrix of sintered porous material, such as sintered glass, sintered steel, sintered ceramics, sintered plastics, and equivalents thereof. The matrix is characterized by a reproducible fluid uptake capacity proportional to the fixed dimensions of said matrix, a minimal reactivity with plasma or serum components, and a hydrophilic internal surface which enables the matrix to collect and retain a predetermined volume of sample for analysis.

    Abstract translation: 允许血浆或血清从全血分离的装置和方法。 该装置包括已经施加至少一种红细胞凝集剂的亲水性烧结多孔材料的基质。 根据使用该装置的第一种方法,将全血样品施加到基质的第一端,并且样品内的红细胞与存在于基质中的凝集剂接触。 血细胞凝集,并被截留在基质的空隙中,而基本上无血细胞的血清或血浆聚集在装置的出口附近。 与基质液体接收关系的过滤装置用于从基质中吸收血浆的血清。 根据本发明的另一方面,与基质的出口液体接收关系的过滤器装置用于保持通过基质的任何血细胞,因为过滤器装置将血浆或血清从基质中吸出。 可以在过滤器装置内并入额外的凝集剂以促进通过基质的血细胞的保留。 本发明的另一方面涉及一种利用烧结多孔材料如烧结玻璃,烧结钢,烧结陶瓷,烧结塑料及其等同物的基质来测量血清或血浆样品的装置。 该基质的特征在于与所述基质的固定尺寸成比例的可再现的流体吸收能力,与血浆或血清组分的最小反应性,以及亲水性内表面,其使基质收集并保留预定体积的样品用于分析。

    Method of producing open-pore sintered glass filters and product
    25.
    发明授权
    Method of producing open-pore sintered glass filters and product 失效
    生产开孔烧结玻璃过滤器和产品的方法

    公开(公告)号:US4927442A

    公开(公告)日:1990-05-22

    申请号:US323088

    申请日:1989-03-14

    CPC classification number: B01D39/201 C03B19/06 Y10T428/24999

    Abstract: Filter bodies are made by mixing borosilicate glass powder, potassium sulphate and 30% aqueous polyethylene glycol solution per kilogram of mixture. The mixture is filtered and dried and glass particles of a different size are mixed into the dried granulate. The resulting mixture is compressed at a pressure of 1000 bar to form blanks and sintered at about 860.degree. C. After cooling, the potassium sulphate is washed out of the blanks.

    Abstract translation: 过滤体通过每千克混合物混合硼硅酸盐玻璃粉末,硫酸钾和30%聚乙二醇水溶液制成。 将混合物过滤并干燥,将不同大小的玻璃颗粒混入干燥的颗粒中。 将所得混合物在1000巴的压力下压缩以形成坯料并在约860℃下烧结。冷却后,将硫酸钾从坯料中冲洗掉。

    Filter membrane and method of manufacturing it
    26.
    发明授权
    Filter membrane and method of manufacturing it 失效
    过滤膜及其制造方法

    公开(公告)号:US4698157A

    公开(公告)日:1987-10-06

    申请号:US763305

    申请日:1985-08-05

    Applicant: Jacques Gillot

    Inventor: Jacques Gillot

    Abstract: A filter membrane for filtering liquid food stuffs or hot gases and including at least one filter layer. The membrane is constituted by a sintered inorganic material comprising grains which are fixedly connected to one another and the average roughness of the surface of said filter layer over a distance along said surface equal to at least five times the average grain size is less than one fifth of the average grain size in the region in question.

    Abstract translation: 一种用于过滤液体食物或热气体并包括至少一个过滤层的过滤膜。 该膜是由烧结的无机材料构成的,该无机材料包括彼此固定连接的颗粒,并且所述过滤层的表面沿着所述表面的距离的平均粗糙度等于平均晶粒尺寸的至少五倍小于五分之一 在该地区的平均粒度。

    SINTERED GLASS BEAD FILTER WITH ACTIVE MICROBIAL DESTRUCTION
    27.
    发明申请
    SINTERED GLASS BEAD FILTER WITH ACTIVE MICROBIAL DESTRUCTION 审中-公开
    活性微生物破坏的烧结玻璃珠过滤器

    公开(公告)号:WO2004030808A2

    公开(公告)日:2004-04-15

    申请号:PCT/US2003/026619

    申请日:2003-08-26

    Abstract: A microbicidal filter system having superior drop pressure and low complexity is provided, as well as a method for producing the same. The system comprises a plurality of glass beads having pores formed therebetween for the flow of air therethrough. The sintered glass beads are coated in a transition metal oxide and water. An ultraviolet light source is used to cause a photocatalytic reaction between the transition metal oxide and water. Free hydroxyl radicals with microbicidal properties are produced. Urethane foam may be inserted between the glass beads before sintering in order to cause a bimodal pore size distribution, and particulates disposed on the glass beads may be added to alter surface activity.

    Abstract translation: 本发明提供了一种具有优良的压降和低复杂性的杀菌过滤系统及其生产方法。 该系统包括多个玻璃珠,其间形成有用于空气流动的孔隙。 烧结的玻璃珠涂覆在过渡金属氧化物和水中。 紫外光源用于引起过渡金属氧化物和水之间的光催化反应。 产生具有杀微生物特性的游离羟基自由基。 聚氨酯泡沫可以在烧结之前插入玻璃珠之间以引起双峰孔尺寸分布,并且可以添加设置在玻璃珠上的颗粒以改变表面活性。

    Sinter Bonded Porous Metallic Coatings
    30.
    发明申请
    Sinter Bonded Porous Metallic Coatings 审中-公开
    烧结多孔金属涂层

    公开(公告)号:US20140193661A1

    公开(公告)日:2014-07-10

    申请号:US14149196

    申请日:2014-01-07

    Abstract: A composite structure includes a substrate with pores of a first mean pore size and a coating on at least one surface of that substrate. This coating has pores of a second mean pore size where the first mean pore size is equal to or greater than said second mean pore size. When the pore size of the coating is effective to capture particulate greater than 0.2 micron, the composite may be formed into a filter effective to remove microbes from a fluid medium. One method to form the porous coating on the substrate includes the steps of: (a) forming a suspension of sinterable particles in a carrier fluid and containing the suspension in a reservoir; (b) maintaining the suspension by agitation in the reservoir; (c) immersing the substrate in the reservoir; (c) applying a first coating of the suspension to the substrate; (d) removing the substrate with the applied first coating from the reservoir; and (e) sintering the sinterable particles to the substrate thereby forming a coated substrate.

    Abstract translation: 复合结构包括具有第一平均孔径的孔和在该基底的至少一个表面上的涂层的基底。 该涂层具有第二平均孔径的孔,其中第一平均孔径等于或大于所述第二平均孔径。 当涂层的孔径有效捕获大于0.2微米的颗粒时,复合材料可形成有效去除流体介质中微生物的过滤器。 在基材上形成多孔涂层的一种方法包括以下步骤:(a)在载体流体中形成可烧结颗粒的悬浮液并将其悬浮液储存在容器中; (b)通过搅拌将储存器中的悬浮液维持在储存器中; (c)将基材浸入储存器中; (c)将所述悬浮液的第一涂层施加到所述基底上; (d)从所述储存器用所施加的第一涂层去除所述基材; 和(e)将可烧结颗粒烧结到基底上,从而形成涂覆的基底。

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