公开(公告)号：EP2875339A1

公开(公告)日：2015-05-27

申请号：EP13756571.9

申请日：2013-07-18

Applicant: MSC&SGCC

Inventor： COLLE, Olivier ,  DROUET, Florence ,  LECONTE, Marc

IPC: G01N21/90 ,  G01N21/88

CPC classification number: G01N21/90 ,  G01N21/8851 ,  G01N21/958 ,  G01N2021/8832 ,  G01N2201/0484 ,  G01N2201/062

Abstract: The invention relates to an in-line optical method of inspecting transparent or translucent containers (3) travelling between a light source (7) and a system (9) for taking images of the containers and analysing the images taken. According to the invention, the method comprises the steps of: illuminating each container (3) using the light source (7) having a light intensity variation according to a periodic pattern (7
1 ) of period T
1 along at least one first direction of variation (D); for each container (3), taking a number of images N, greater than or equal to three, of the container passing in front of the light source and occupying respectively N different positions along the length of the path; between each image capture, creating a relative shift between the container and the periodic pattern according to a direction of variation (D) of the periodic pattern (7
1 ); determining and applying a geometric transformation in at least N-1 images of a single container for at least one set of points belonging to the container, in order to align the pixels belonging to the container in the N successive images of a single container; for each container (3), constructing a phase image from the N adjusted images of the container; and analysing the phase image in order to deduce therefrom at least the presence of a light-refracting defect or the distribution quality of the material forming the container.

公开(公告)号：EP2859325A2

公开(公告)日：2015-04-15

申请号：EP13736975.7

申请日：2013-06-06

Applicant: Bio-Rad Laboratories, Inc.

Inventor： URI, Yochanan ,  RAN, Boaz ,  NOTCOVICH, Ariel G. ,  NIMRI, Shay

IPC: G01N21/03 ,  G01N21/55

CPC classification number: G01N21/553 ,  G01N21/253 ,  G01N21/658 ,  G01N33/54373 ,  G01N2021/0328 ,  G01N2201/0407 ,  G01N2201/0484 ,  G01N2201/062

Abstract: A tip for use in an optical detection system to analyze an analyte in a fluid sample drawn into the tip, using light reflected from a detection surface inside the tip that the analyte binds to, comprising a first detection surface and a second detection surface located in a same flow path with no controllable valve separating them, wherein the first and second detection surfaces have different surface chemistries.

公开(公告)号：EP0154743A3

公开(公告)日：1987-01-14

申请号：EP84307922

申请日：1984-11-15

Applicant: Rock, Gail Ann ,  Gardell, Dietlind

Inventor： Rock, Gail Ann

IPC: G01N21/64 ,  G02B21/16 ,  G01N35/02

CPC classification number: G01N21/6428 ,  G01N21/6452 ,  G01N21/6458 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2201/0446 ,  G01N2201/0484 ,  Y10S435/963 ,  Y10S435/966 ,  Y10S435/973 ,  Y10S436/80 ,  Y10S436/805 ,  Y10S436/807 ,  Y10S436/808 ,  Y10S436/809 ,  Y10S436/821

Abstract: An automated system for rapid sequential photometric analysis of a collection of double fluorochrome stained lymphocyte specimens, useful for antibody screening or lymphocytotoxicity analysis. The specimens are sequentially alternately irradiated with light of two distinguishable wavelengths, producing fluorescence at two distinguishable wavelengths. The fluorescent emission light intensity for each irradiation of each specimen is measured using a photometer and computer. The computer controls the synchronization of the irradiation through alternately selected condenser sets with the sequential movement of specimens Into the optical path of the irradiating and detected light, and calculates the ratio of the light intensities emitted from each specimen at the two selected fluorescent light wavelengths. These ratios are compared against a control ratio (for lymphocytotoxicity analysis) to classify the specimen. Also described is a method of preparing specimens for such analysis, which requires that a complement be added to the first staining solution after the latter is applied to the specimens, then this combination agitated, and then the second staining solution added and the specimen incubated.

公开(公告)号：JPWO2014156379A1

公开(公告)日：2017-02-16

申请号：JP2015508172

申请日：2014-02-19

Applicant: ソニー株式会社

Inventor： 直樹 森本 ,  森本　　直樹 ,  甲斐　慎一 ,  慎一 甲斐

IPC: G01N21/27

CPC classification number: G01N21/6428 ,  G01N21/01 ,  G01N21/27 ,  G01N21/274 ,  G01N21/6452 ,  G01N2021/0175 ,  G01N2021/1753 ,  G01N2021/178 ,  G01N2021/1789 ,  G01N2021/6419 ,  G01N2021/6439 ,  G01N2021/6441 ,  G01N2201/0446 ,  G01N2201/0453 ,  G01N2201/0484

Abstract: 一連の光強度データにおける試料の収容領域に対応する範囲の特定を精度高く行うことが可能なデータ処理装置の提供。第1の光源から検出領域に向けて出射された光に基づいて得られる第1の光強度分布データと第2の光源から前記検出領域に向けて出射された光に基づいて得られる第2の光強度分布データの各々について、検出対象が収容される収容領域に対応する解析対象範囲を特定するデータ判定部と、該データ判定部の動作モードを選択するモード選択部とを有し、前記モード選択部は、前記データ判定部が、前記第1の光強度分布データ及び前記第2の光強度分布データの各々から、前記解析対象範囲を特定する第1のモードと、前記データ判定部が、前記第1の光強度分布データの前記解析対象範囲に関する情報に基づき、前記第2の光強度分布データから前記解析対象範囲を特定する第2のモードの何れか一方を選択するデータ処理装置を提供する。

Abstract translation: 提供一组识别高精度能够执行对应于该光强度数据样本的容纳区域的范围的数据处理装置的。 第一首先基于从光源朝向所述检测区域发射的光强度分布数据的光和来自第二光源朝向所述检测区域发射的光的基础上获得的第二获得 对于每个光强度分布数据包括一数据确定单元，用于指定对应于接收区域，其中所述检测对象被容纳在分析的目标范围，以及用于选择的数据的操作模式判断单元的模式选择器，该模式 选择单元，所述数据判断部，从所述第一光强度分布数据和所述第二光强度分布的数据，用于指定分析对象范围内的第一模式中，数据判定部， 基于上的光强度分布数据的分析范围中的第一信息，用于选择所述第二模式中的一个用于指定所述第二光强度分布的数据的分析范围提供了一个数据处理装置 到。

公开(公告)号：JP2004170426A

公开(公告)日：2004-06-17

申请号：JP2003390267

申请日：2003-11-20

Applicant: Agilent Technol Inc ,  アジレント・テクノロジーズ・インクAgilent Technologies, Inc.

Inventor： SILLMAN DEBRA A ,  ZHOU XIANGYANG ,  JADHAW CHETAN D ,  CATTELL HERBERT F ,  GHOSH JAYATI

IPC: G01N21/64 ,  G01N33/52 ,  G01N33/58 ,  G01N33/68

CPC classification number: G01N21/6452 ,  G01N33/52 ,  G01N33/582 ,  G01N33/68 ,  G01N2201/0484

Abstract: PROBLEM TO BE SOLVED: To provide a program making method of an array scanner for scanning a plurality of biopolymeric arrays.
SOLUTION: This invention selects an individual scanning parameter on at least two different arrays from among a plurality of arrays of a scanning object, and inputs the scanning parameter to the array scanner before scanning the plurality of arrays. Then, the scanner for making the program scans the plurality of arrays according to a preselected scanning parameter, and also includes a scanner for not only making a computer program for making the program of the scanner according to this invention but also making the program according to this invention. The method and a composition of this invention are to detect uses for the various different applications including both applications of genomics (a genome analysis) and proteomics (protein analysis).
COPYRIGHT: (C)2004,JPO

Abstract translation: 要解决的问题：提供用于扫描多个生物聚合物阵列的阵列扫描仪的程序制作方法。 解决方案：本发明在扫描对象的多个阵列中的至少两个不同的阵列上选择单独的扫描参数，并且在扫描多个阵列之前将扫描参数输入到阵列扫描器。 然后，用于制作程序的扫描仪根据预选的扫描参数扫描多个阵列，并且还包括扫描仪，用于不仅制作用于制作根据本发明的扫描仪的程序的计算机程序，而且还使根据 本发明。 本发明的方法和组合物用于检测各种不同应用的应用，包括基因组学（基因组分析）和蛋白质组学（蛋白质分析）两者的应用。 版权所有（C）2004，JPO

公开(公告)号：US20240210426A1

公开(公告)日：2024-06-27

申请号：US18087391

申请日：2022-12-22

Applicant: The United States of America, as represented by the Secretary of Agriculture ,  NATIONAL AGRICULTURAL PRODUCTS QUALITY MANAGEMENT SERVICE

Inventor： MOON S. KIM ,  JIANWEI QIN ,  JO ANN S. VAN KESSEL ,  JEEHWA HONG ,  HYUNJEONG CHO

IPC: G01N35/00 ,  C12Q1/04 ,  G01N21/27 ,  G01N21/65

CPC classification number: G01N35/00029 ,  C12Q1/04 ,  G01N21/27 ,  G01N21/65 ,  G01N2201/0484

Abstract: The portable multimodal optical sensing system is an integrated system/tool for intelligent food safety inspection. The system includes a pair of lasers and corresponding spectrometers working at different wavelengths to enable an operator to obtain high-quality Raman scattering data from both low- and high-fluorescence food samples. By utilizing machine vision and motion control techniques, the system can conduct fully automated spectral data acquisition for randomly scattered samples that are deposited in Petri dishes or placed in customized well plates.

公开(公告)号：US12007334B2

公开(公告)日：2024-06-11

申请号：US17510185

申请日：2021-10-25

Applicant: Applied Materials, Inc.

Inventor： Asaf Schlezinger

IPC: G01N21/90 ,  G01N35/04

CPC classification number: G01N21/9009 ,  G01N35/04 ,  G01N2035/0406 ,  G01N2035/0415 ,  G01N2201/0484 ,  G01N2201/0636

Abstract: Methods and apparatus of inspection tools for inspecting impurities in vials are provided herein. In some embodiments, an inspection tool for inspecting impurities in vials includes: a table for inspecting a plurality of vials; one or more carts configured to move about the table to place the one or more carts in an inspection position, wherein each of the one or more carts includes a vial holder configured to hold a plurality of vials, and wherein each vial holder is configured to spin the plurality of vials on their own respective axes; and a camera configured to take images of the plurality of vials when the plurality of vials are disposed in the inspection position.

公开(公告)号：US09551671B2

公开(公告)日：2017-01-24

申请号：US14416369

申请日：2013-07-18

Applicant: MSC & SGCC

Inventor： Olivier Colle ,  Florence Drouet ,  Marc Leconte

IPC: G01N21/00 ,  G01N21/90 ,  G01N21/958 ,  G01N21/88

CPC classification number: G01N21/90 ,  G01N21/8851 ,  G01N21/958 ,  G01N2021/8832 ,  G01N2201/0484 ,  G01N2201/062

Abstract: An in-line method for optically inspecting transparent or translucent containers (3) comprises illuminating each container with a light source that presents light intensity variation in a periodic pattern along at least a first variation direction. A number N greater than or equal to three of images of the container traveling in front of the light source and occupying N different respective positions along the travel path is taken. Between taking successive images, a relative shift between the container and the periodic pattern is created. A geometrical transformation is determined and applied in order to put the pixels belonging to the container in the N successive images of the same container into coincidence. A phase image for each container is constructed using the N registered images of the container. The phase image is analyzed in order to deduce therefrom at least the presence of defects or the quality of the container.

Abstract translation: 用于光学检查透明或半透明容器（3）的在线方法包括用沿着至少第一变化方向呈现周期性图案的光强度变化的光源照亮每个容器。 采取大于或等于在光源前面行进并且沿着行进路径占据N个不同位置的容器的图像的三个数量N。 在拍摄连续图像之间，创建容器和周期性图案之间的相对位移。 确定并应用几何变换以将属于容器的像素放入同一容器的N个连续图像中。 使用容器的N个记录图像来构建每个容器的相位图像。 分析相位图像以便至少从其中推导出缺陷的存在或容器的质量。

公开(公告)号：US20160282268A1

公开(公告)日：2016-09-29

申请号：US14778120

申请日：2014-02-19

Applicant: Sony Corporation

Inventor： Naoki Morimoto ,  Shinichi Kai

IPC: G01N21/64 ,  G01N21/27 ,  G01N21/01

CPC classification number: G01N21/6428 ,  G01N21/01 ,  G01N21/27 ,  G01N21/274 ,  G01N21/6452 ,  G01N2021/0175 ,  G01N2021/1753 ,  G01N2021/178 ,  G01N2021/1789 ,  G01N2021/6419 ,  G01N2021/6439 ,  G01N2021/6441 ,  G01N2201/0446 ,  G01N2201/0453 ,  G01N2201/0484

Abstract: There is provided a data processing apparatus including: a data determination portion that specifies, in each of first and second light intensity distribution data, an analysis range corresponding to a storage area for storing a detection target, the first and second light intensity distribution data being acquired on the basis of light emitted from first and light sources to a detection area; and a mode selection portion that selects an operation mode of the data determination portion. The mode selection portion selects one of a first mode in which the data determination portion specifies the analysis range in each of the first light intensity distribution data and the second light intensity distribution data, and a second mode in which the data determination portion specifies the analysis range in the second light intensity distribution data on the basis of information on the analysis range of the first light intensity distribution data.

Abstract translation: 提供了一种数据处理装置，包括：数据确定部，其在第一和第二光强分布数据中的每一个中指定与用于存储检测对象的存储区域对应的分析范围，第一和第二光强度分布数据为 基于从第一和光源发射的光到检测区域获取; 以及选择数据确定部分的操作模式的模式选择部分。 模式选择部分选择第一模式，其中数据确定部分指定第一光强分布数据和第二光强分布数据中的每一个中的分析范围，第二模式中数据确定部分指定分析 基于关于第一光强度分布数据的分析范围的信息，在第二光强分布数据的范围内。

公开(公告)号：US20130330230A1

公开(公告)日：2013-12-12

申请号：US13911115

申请日：2013-06-06

Applicant: Bio-Rad Laboratories Inc.

Inventor： Yochanan URI ,  Boaz Ran ,  Ariel G. Notcovich ,  Shay Nimri

IPC: G01N21/65

CPC classification number: G01N21/553 ,  G01N21/253 ,  G01N21/658 ,  G01N33/54373 ,  G01N2021/0328 ,  G01N2201/0407 ,  G01N2201/0484 ,  G01N2201/062

Abstract: A tip for use in an optical detection system to analyze an analyte in a fluid sample drawn into the tip, using light reflected from a detection surface inside the tip that the analyte binds to, comprising a first detection surface and a second detection surface located in a same flow path with no controllable valve separating them, wherein the first and second detection surfaces have different surface chemistries.

Abstract translation: 一种用于光学检测系统的尖端，用于使用从分析物结合到所述尖端内部的检测表面反射的光来分析吸入所述尖端的流体样品中的分析物，所述检测表面包括第一检测表面和位于 相同的流动路径，没有可分离它们的可控阀，其中第一和第二检测表面具有不同的表面化学性质。