公开(公告)号：EP2596329A1

公开(公告)日：2013-05-29

申请号：EP11746641.7

申请日：2011-07-19

Applicant: Commissariat à l'Énergie Atomique et aux Énergies Alternatives

Inventor： NICOLETTI, Sergio

IPC: G01N15/02 ,  G01N21/53

CPC classification number: G01N15/0211 ,  G01N15/06 ,  G01N15/1484 ,  G01N21/53 ,  G01N21/532 ,  G01N2015/0038 ,  G01N2021/4726 ,  G01N2201/06113 ,  G01N2201/0873

Abstract: The invention relates to a particle detector including a substrate (10, 30, 40) made of a semiconductor material, in which at least one through-cavity (11, 31, 41) is formed, defined by an input section (110) and an output section (111), wherein the input section thereof is to be connected to an airflow source, said substrate supporting: an optical means including at least one laser source (12, 32, 42), and at least one waveguide (13, 33, 43) connected to said at least one laser source and leading into the vicinity of the output section of said cavity; and photodetector means (14, 34, 44) located near the output section of said cavity and offset relative to the optical axis of the optical means.

公开(公告)号：EP1896833A2

公开(公告)日：2008-03-12

申请号：EP06765778.3

申请日：2006-06-19

Applicant: Philips Intellectual Property & Standards GmbH ,  Koninklijke Philips Electronics N.V. ,  Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.

Inventor： MOENCH, Holger, Philips IP &Standards GmbH ,  HEUSLER, Gero, Philips IP &Standards GmbH ,  WEICHMANN, Ulrich, Philips IP &Standards GmbH ,  GOTTMANN, Jens, Philips IP &Standards GmbH

IPC: G01N21/77 ,  G01N21/64 ,  H01S3/063 ,  H01S3/102

CPC classification number: G01N21/6428 ,  G01N21/552 ,  G01N21/6402 ,  G01N21/6452 ,  G01N21/648 ,  G01N21/7703 ,  G01N2021/392 ,  G01N2021/6441 ,  G01N2021/7786 ,  G01N2201/06113 ,  G01N2201/0873 ,  H01S3/0632 ,  H01S3/0637 ,  H01S3/094084 ,  H01S3/09415 ,  H01S3/1608 ,  H01S3/173 ,  H01S3/2383

Abstract: The present invention relates to a detection device for detecting target substances in samples. The device comprises a substrate (1) with at least one planar waveguide laser (2) in or on said substrate (1), said waveguide laser (2) having a gain medium (5) for up-conversion or for down-conversion. A top layer (3) of said waveguide laser (2) forms at least part of a surface of said substrate (1) and allows formation of an evanescent wave in a sample contacting said surface. A structure is applied on said top layer (3) to define an array of probe regions (4) on said top layer (3), said probe regions (4) consisting of a coating of probe materials for sensing said target substances to be detected. The present detection device allows a parallel detection of target substances with a highly integrated design.

公开(公告)号：EP0487992A2

公开(公告)日：1992-06-03

申请号：EP91119499.1

申请日：1991-11-15

Applicant: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.

Inventor： Brandenburg, Albrecht, Dr. ,  Hutter, Frank, Dr. ,  Edelhäuser, Rainer

IPC: G01N21/45

CPC classification number: G01N21/7703 ,  G01J2009/023 ,  G01N21/45 ,  G01N21/783 ,  G01N2021/7779 ,  G01N2201/0873

Abstract: Ein optischer Sensor (1) weist eine integriert optische Anordnung zur Messung des optischen Absorptionskoeffizienten und der Brechzahl flüssiger oder gasförmiger Medien auf. Dieser optische Sensor kann als Interferometer ausgebildet sein, wobei in einem Wellenleiter-Zweig (4b) ein sensitiver Bereich (6) vorgesehen ist. In diesem sensitiven Bereich ist der Wellenleiterabschnitt des Wellenleiter-Zweiges (4b) mit einer sensitiven Schicht (8) aus einem Heteropolysiloxan überdeckt. Die übrigen Wellenleiterabschnitte sind durch eine dielektrische Schicht (7) abgedeckt.
Durch die sensitive Schicht (8) aus einem Heteropolysiloxan ist in vorteilhafterweise eine selektive Wechselwirkung mit dem nachzuweisenden Stoff ermöglicht. Unter dem Einfluß des nachzuweisenden Stoffes ändert die sensitive Schicht (8) ihre optischen Eigenschaften, die entsprechend ausgewertet werden. Der optische Sensor kann insbesondee auch dort eingesetzt werden, wo elektrische Sensoren problematisch sind, insbesondere in der Umgebung von starken elektromagnetischen Impulsen oder HF-Strahlung oder auch in explosionsgefährdeter Umgebung.

Abstract translation: 光学传感器（1）具有用于测量液体或气体介质的光学吸收系数和折射率的集成光学装置。 所述光学传感器可以被设计为干涉仪，敏感区域（6）设置在波导分支（4b）中。 在所述敏感区域中，波导管（4b）的波导部分被由异质聚硅氧烷制成的敏感层（8）覆盖。 剩余的波导段由电介质层（7）屏蔽。 由杂多硅氧烷组成的敏感层（8）有利地使得与待检测物质的选择性相互作用成为可能。 敏感层（8）的光学性质在受检物质的影响下发生变化，适当评价。 特别是，即使在电传感器存在问题的地方，特别是在强电磁脉冲或HF辐射附近，甚至在爆炸环境中也可以使用光学传感器。

公开(公告)号：US20230324288A1

公开(公告)日：2023-10-12

申请号：US18011570

申请日：2021-06-24

Applicant: Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNO

Inventor： Arjen BOERSMA ,  Javier NUNEZ VILLANUEVA ,  Evert Jonathan VAN DEN HAM

IPC: G01N21/3504 ,  C03C25/106

CPC classification number: G01N21/3504 ,  C03C25/1061 ,  G01N2201/0873 ,  G01N2201/061

Abstract: A sensor system, the manufacturing of such system, and the use of such system for optical detection of a target analyte in a gaseous medium are described. The sensor system includes a hollow waveguide that is provided with a reflective mirror layer along its inner wall and a concentrating coating of an inorganic sorption material. The mirror layer defines a light path for guiding light between a light inlet and a light outlet that are provided on opposing terminal ends of the hollow waveguide. The concentrating coating increases an effective concentration of target analytes, if present, and allows optical, preferably spectroscopic, analysis of the medium by recording transmission of light, preferably infrared light, guided through the hollow waveguide.

公开(公告)号：US20230160823A1

公开(公告)日：2023-05-25

申请号：US17423941

申请日：2021-03-12

Applicant: BOE TECHNOLOGY GROUP CO., LTD.

Inventor： Mengjun HOU ,  Qiong WU ,  Youxue WANG ,  Kai GENG ,  Zhukai LIU ,  Jing Yu

IPC: G01N21/64 ,  G01N21/17

CPC classification number: G01N21/6428 ,  G01N21/1717 ,  G01N2201/0873

Abstract: The present disclosure provides an analysis device for a detection chip, an analysis system and a method of operating the analysis device. The analysis device includes a loading part, a temperature control part and a signal detection part. The loading part is configured to receive and hold the detection chip in use and is capable of moving the detection chip. The temperature control part includes a heater and a cooler, the heater is configured to heat the detection chip and the cooler is configured to cool the detection chip. The signal detection part includes an optical sensor. The optical sensor is configured to receive light from the detection chip and perform detection according to the light.

公开(公告)号：US20180258917A1

公开(公告)日：2018-09-13

申请号：US15913277

申请日：2018-03-06

Applicant: Hitachi, Ltd.

Inventor： Ryo UETA ,  Mitsuru SAEKI

IPC: F03D17/00 ,  F03D1/06 ,  G02B6/44 ,  G02B6/02 ,  G01L1/24 ,  G01N21/95

CPC classification number: F03D17/00 ,  F03D1/0675 ,  F05B2240/2211 ,  F05B2240/912 ,  F05B2270/804 ,  F05B2270/808 ,  F05B2280/6003 ,  G01B11/18 ,  G01L1/242 ,  G01L1/246 ,  G01L1/26 ,  G01M5/0016 ,  G01N21/95 ,  G01N2201/0873 ,  G01N2201/088 ,  G02B6/02076 ,  G02B6/4432 ,  Y02E10/721 ,  Y02E10/726 ,  Y02E10/728

Abstract: To provide a wind turbine blade or a wind power generation device provided with a strain detecting system having a high level of soundness. The blade includes a structural material constituting the blade, plural optical fibers 15A and 15B arranged within or on a surface of the structural material, and an optical cable 16A that connects adjacent ones of the optical fiber sensors, and a length of the optical cable 16A is longer than the shortest distance between the adjacent optical fiber sensors.

公开(公告)号：US20180239087A1

公开(公告)日：2018-08-23

申请号：US15953792

申请日：2018-04-16

Applicant: Pacific Biosciences of California, Inc.

Inventor： Ravi SAXENA ,  Michael Tzu RU ,  Takashi Whitney ORIMOTO ,  Annette GROT ,  Mathieu FOQUET ,  Hou-Pu CHOU

IPC: G02B6/12 ,  G02B6/124 ,  B29D11/00 ,  G01N21/64 ,  B29D17/00 ,  G02B5/18 ,  G02B6/136 ,  C12Q1/6869 ,  G02B6/02 ,  B29L11/00

CPC classification number: G02B6/12004 ,  B29D11/0073 ,  B29D17/007 ,  B29L2011/005 ,  B29L2011/0066 ,  B29L2011/0075 ,  C12Q1/6869 ,  G01N21/6454 ,  G01N21/648 ,  G01N2021/6478 ,  G01N2201/0873 ,  G02B5/189 ,  G02B6/02123 ,  G02B6/124 ,  G02B6/136 ,  G02B2006/12038 ,  G02B2006/12109

Abstract: Arrays of integrated analytical devices and their methods for production are provided. The arrays are useful in the analysis of highly multiplexed optical reactions in large numbers at high densities, including biochemical reactions, such as nucleic acid sequencing reactions. The integrated devices allow the highly sensitive discrimination of optical signals using features such as spectra, amplitude, and time resolution, or combinations thereof. The arrays and methods of the invention make use of silicon chip fabrication and manufacturing techniques developed for the electronics industry and highly suited for miniaturization and high throughput.

公开(公告)号：US20180113068A1

公开(公告)日：2018-04-26

申请号：US15570958

申请日：2015-07-24

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Timothy L. Weber

IPC: G01N21/05 ,  G01N21/64 ,  G01N21/59 ,  G01N21/11

CPC classification number: G01N21/05 ,  B01L3/50273 ,  B01L2300/0816 ,  B01L2400/0442 ,  G01N21/11 ,  G01N21/59 ,  G01N21/6428 ,  G01N2021/0328 ,  G01N2021/0346 ,  G01N2021/6439 ,  G01N2021/7783 ,  G01N2021/7786 ,  G01N2201/0221 ,  G01N2201/024 ,  G01N2201/0873

Abstract: In one example, testing cells extend along a length of a slot. Each testing cell includes a microfluidic channel extending from the slot, a pump to move fluid from the slot into the channel, a discharge nozzle through which fluid exits the channel, a fluid discharger to discharge fluid from the channel through the nozzle and a photosensor. A light guide is provided to receive light from an external light source and is to serially transmit the light to the microfluidic channel of each of the plurality of testing cells.

公开(公告)号：US09929292B2

公开(公告)日：2018-03-27

申请号：US15423836

申请日：2017-02-03

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Tatsuo Dougakiuchi ,  Akio Ito ,  Tadataka Edamura ,  Kazuue Fujita

IPC: G01N21/3504 ,  H01L31/0352 ,  H01L31/0304 ,  H01L31/109 ,  H01L31/0216 ,  H01L31/0232

CPC classification number: H01L31/035236 ,  G01N21/3504 ,  G01N2201/068 ,  G01N2201/0873 ,  H01L31/02161 ,  H01L31/02327 ,  H01L31/03042 ,  H01L31/03046 ,  H01L31/035281 ,  H01L31/109

Abstract: A quantum cascade detector includes a semiconductor substrate; an active layer having a cascade structure; a lower cladding layer provided between the active layer and the substrate and having a lower refractive index than the active layer; a lower metal layer provided between the lower cladding layer and the substrate; an upper cladding layer provided on an opposite side to the substrate with respect to the active layer and having a lower refractive index than the active layer; and an upper metal layer provided on an opposite side to the active layer with respect to the upper cladding layer. A first end face being in a waveguide direction in a waveguide structure with the active layer, lower cladding layer, and upper cladding layer is an entrance surface for light to be detected.

公开(公告)号：US09857299B2

公开(公告)日：2018-01-02

申请号：US15478982

申请日：2017-04-04

Applicant: Colorado State University Research Foundation

Inventor： Kevin Lear ,  Timothy Erickson

IPC: G02B6/00 ,  G01N21/41 ,  G01N33/18 ,  G01M11/00 ,  G02B6/122 ,  G02B6/12

CPC classification number: G01N21/4133 ,  G01M11/33 ,  G01N33/1833 ,  G01N2021/4166 ,  G01N2201/0873 ,  G02B6/028 ,  G02B6/12004 ,  G02B6/1221 ,  G02B6/4291 ,  G02B27/56 ,  G02B2006/12123 ,  G02B2006/12138 ,  Y02A20/206

Abstract: A chip-scale, reusable sensor can detect aromatic hydrocarbons, such as benzene, toluene, ethylbenzene, and xylenes (BTEX), rapidly in water without sample preparation. The device is capable of real-time, continuous monitoring for BTEX solutes, which diffuse into a film, such as a polymer, on the sensors surface. In operation, BTEX analytes concentrate in the film, causing an increase in refractive index, which modulates evanescent coupling into the chips integrated photodetector array. Integration of the photodetector array simplifies system instrumentation and permits incorporation of an on-chip photocurrent reference region in the immediate vicinity of the sensing region, reducing drift due to temperature fluctuations. In some examples, the chip responds linearly for BTEX concentrations between 1 ppm and 30 ppm, with a limit of detection of 359 ppb, 249 ppb, and 103 ppb for benzene, toluene, and xylene in water, respectively.