公开(公告)号：EP0176353A3

公开(公告)日：1988-11-30

申请号：EP85306795

申请日：1985-09-24

Applicant: SOUTHWEST RESEARCH INSTITUTE

Inventor： Rollwitz, William J.

IPC: A61B05/05 ,  G01N24/08

CPC classification number: G01R33/34053 ,  A61B8/0825 ,  A61B8/406 ,  G01R33/383 ,  G01R33/50

Abstract: A method and apparatus for testing for cancer cells in the human breast is set forth. In the preferred and illustrated embodiment, a pendulant breast exposed to a magnetic field is tested by nuclear magnetic resonant (NMR). The magnetic field is varied to provide the requisite field intensity in selected segmented sections of the pendulant breast within the field. The field intensity is varied to thereby observe all of the breast extending toward the thorax cavity, obtaining test data from section after section aggregating test data from the entire breast within the pole pieces of the magnet and sufficiently therebeyond to obtain full interrogation. The NMR response focuses on hydrogen nuclei in the water in the breast region, determines the voltage proportional to the density of hydrogen nuclei and the binding of the water described by the relaxation times T, and T 2 for each binding level for water. The data so obtained in sequence is examined. Difference values from sequentially obtained signals are evaluated, yielding a plot of different signals as a function of breast length, thereby yielding abnormalities. Such abnormalities are shown in the difference signal from NMR interrogation as a result the concentration and relaxation time (T, and T 2 ) changes in tumors.

公开(公告)号：EP0219206A3

公开(公告)日：1987-09-16

申请号：EP86306320

申请日：1986-08-15

Applicant: TECHNICARE CORPORATION

Inventor： Compton, Russell Allen ,  Keller, John Timothy ,  McBride, Thomas Robert ,  Kramer, David Moses

IPC: A61B05/05 ,  G01N24/00

CPC classification number: G01R33/583

Abstract: In a magnetic resonance imaging system, the same reference signal is used for both radio frequency transmission and phase sensitive detection. The use of the same reference signal for both transmission and reception prevents phase unlock between the two events. However, this technique results in variation in the demodulated, frequency encoded information, which is corrected by digitally filtering the received signal information as a function of the demodulation frequency used.

公开(公告)号：EP0156239A3

公开(公告)日：1986-10-15

申请号：EP85102818

申请日：1985-03-12

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Laskaris, Evangelos Trifon

IPC: F17C03/08 ,  F17C13/00 ,  A61B05/05 ,  G01N24/02

CPC classification number: F17C3/085 ,  F17C2203/0687 ,  F17C2270/0536 ,  Y10S505/892

Abstract: A plug for a horizontal cryostat penetration comprises a plurality of nested housings with thermal insulation disposed between the housings. Each housing has a tubular extension which is heat stationable to portions of the cryostat penetration, the more innerthe housing, the colder being the portion to which it is stationed. The innermost and outermost housings each possess pressure relief means for relieving internal pressure buildup which occurs as a result of magnet quench or vacuum loss. In operation the plug is disposed within the cryostat penetration and in particular, typically within a tubular conduit associated therewith. Thetubular extension ofthe outermost housing also has preferably disposed around its exterior, one or more string-shaped helically disposed lengths of sealing material. Accordingly, when the plug is placed within the penetration, a helical coolant vapor path is formed for plug cooling and exterior ventilation.

公开(公告)号：EP0136812A3

公开(公告)日：1986-08-20

申请号：EP84305829

申请日：1984-08-24

Applicant: TECHNICARE CORPORATION

Inventor： Yeung, Hong-Ning

IPC: G01N24/08 ,  A61B05/05 ,  A61K49/00

CPC classification number: G01R33/5601

Abstract: Reagents for enhancing the contrast of nuclear magnetic images of biological tissues. By contacting the tissues to be imaged with a complex comprising a macromolecule attached to a paramagnetic ion, wherein the macromolecule is tissue specific and the complex has a correlation time of reorientation or a correlation time of rotation of ligands comparable to the Larmor period, the target atom (proton) relaxation rates are altered and the contrast in the images produced by conventional nuclear magnetic resonance techniques is enhanced.

公开(公告)号：EP0091556A3

公开(公告)日：1986-07-23

申请号：EP83102170

申请日：1983-03-05

Applicant: Bruker Medizintechnik GmbH

Inventor： Post, Hans, Dr. ,  Ratzel, Dieter ,  Brunner, Peter, Dr. ,  Knüttel, Bertold

IPC: G01N24/08 ,  A61B05/05

CPC classification number: A61B5/055 ,  G01R33/50

公开(公告)号：EP0125339A3

公开(公告)日：1985-06-05

申请号：EP83108425

申请日：1983-08-26

Applicant: KABUSHIKI KAISHA TOSHIBA

Inventor： Sugimoto, Hiroshi

IPC: G01N24/08 ,  A61B05/05

CPC classification number: G01R33/4835 ,  A61B5/055 ,  G01R33/381

Abstract: In a apparatus for examining an object by nuclear magnetic resonance to produce images of cross-sectional slices (S1, S2, S3) of the object, it necessarily requires to have "a wait time" so as to repeat the applications of the RF pulses toward a plurality of such slices (S1, S2, S3) during one examination cycle. A plurality of coil pairs (8-1,8-2,8-3) is arranged along the longitudianal axis of the object, and each pair is selectively energized so as to apply to the plurality of slices (S1, S2, S3) one of a plurality of gradient fields (G z ) in conjunction with the steady magnetic field (H o ). A plurality of nuclear magnetic resonance signals may be obtained from a plurality of slices during one examination cycle.

公开(公告)号：EP0073375A3

公开(公告)日：1984-09-12

申请号：EP82107332

申请日：1982-08-12

Applicant: Siemens Aktiengesellschaft

Inventor： Krause, Norbert, Dr.

IPC: G01N24/08 ,  A61B05/05

CPC classification number: A61B5/055 ,  G01R33/34046 ,  G01R33/422 ,  Y10S505/844

公开(公告)号：EP0042254A3

公开(公告)日：1982-06-23

申请号：EP81302586

申请日：1981-06-10

Applicant: KABUSHIKI KAISHA TOSHIBA

Inventor： Sugimoto, Hiroshi

IPC: G01N24/08 ,  A61B05/05

CPC classification number: G01R33/385 ,  G01R33/3873 ,  G01R33/54

Abstract: Nuclear magnetic resonance apparatus including magnet apparatus (13) for generating a homogeneous static magnetic field between its magnetic poles, shims (16) of a magnetic substance mounted on the magnetic poles to apply a first gradient magnetic field intensity distribution in a direction rectangular as to the direction of line of magnetic force of the static magnetic field, gradient magnetic field generating electromagnetic apparatus (17) for generating a second gradient magnetic field having a gradient magnetic field intensity distribution in superimposition with the static magnetic field and for changing the magnetic field gradient of the first gradient magnetic field. An oscillator generates an oscillating output having a frequency corresponding to the nuclear magnetic resonance condition of an atomic nucleus to be measured, and a coil (8) wound around a body to be examined is connected to the output of said oscillator. A receiver (7) detects the nuclear magnetic resonance signals received by the coil and a gradient magnetic field controller (20) provides a magnetic field line equivalent to the combined gradient magnetic fields and is arranged to rotate the line along the section of the body to be examined by controlling said gradient magnetic field generating electromagnetic apparatus. A recorder 10 records the nuclear magnetic resonance signals which are then applied to a reconstruction (11) to reconstruct the concentration distribution of the specific atomic nuclei in the section of the body and thence to a display unit for depicting the result of reconstruction.

公开(公告)号：EP0027151A3

公开(公告)日：1982-03-24

申请号：EP79104276

申请日：1979-11-02

Applicant: Rietz, Erhard

Inventor： Leupold, Karl-Heinz, Dr.h.c.

IPC: A61B05/05 ,  A61H39/00 ,  A61N01/18

CPC classification number: A61B5/05 ,  G01R27/02

Abstract: Bei der Schaltungsanordnung für eine Vorrichtung zum Messen des Leitwertes menschlicher Organismen und der Durchführung von Auf- und Abbautherapien unter Verwen dung von mit einem Meßgerät (7) oder einer regelbaren Spannungsquelle in Verbindung bringbaren Berührungselek troden (8, 9) sind die Berührungselektroden durch Schaltglie der wahlweise mit einer Stromquelle (1) und dem Strom meßgerät (7) in Reihe schaltbar oder mit einer Einrichtung zur Erzeugung einer niederfrequenten Kippschwingungsimpuls spannung regelbarer Größe und verschiedener Polarität ver bindbar.

Abstract translation: 在用于测量人体的电导的装置的电路装置中，以及使用可以与测量仪器（7）或可调电压源连接的接触电极（8,9）进行构造和击穿治疗的性能， 接触电极可以通过选择性地与电流源（1）和电流测量仪器（7）串联的开关元件来切换，或者可以与用于产生可调节幅度和不同极性的低频锯齿波振荡脉冲电压的装置连接。

公开(公告)号：EP0218838A3

公开(公告)日：1987-09-02

申请号：EP86111070

申请日：1986-08-11

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Glover, Gary Harold

IPC: A61B05/05 ,  G01N24/08

CPC classification number: G01R33/56509

Abstract: A method for reducing image artifacts due to signal variations in the course of examining a subject using nuclear magnetic resoance (NMR) techniques includes the acquisition of scan data for imaging the object. The scan data is composed of a number of views. The acquisition of each view includes the implementation of a pulse sequence to generate an NMR signal and application of a magnetic gradient along at least one dimensional axis of the object. The magnetic field gradient is characterized by a parameter (e.g., amplitude or direction) adjustable from view to view to encode spatial information into the NMR signal. The parameter value is selected just prior to implementation of the pulse sequence for that view and depends on the phase of the signal variation at that point in time. The final view order depends on the measured phase during the scan. In this manner, the view order can be continuously adjusted to obtain optimum artifact reduction. The method is applicable to various NMR imaging techniques. including Fourier transform and multiple angle projection reconstruction.