反射光測定装置
    311.
    发明申请
    反射光測定装置 审中-公开
    反射光测量装置

    公开(公告)号:WO2014157511A1

    公开(公告)日:2014-10-02

    申请号:PCT/JP2014/058840

    申请日:2014-03-27

    CPC classification number: G01N21/55 G01N2201/064

    Abstract:  窓の天面および底面での反射により生じる迷光の影響を除きつつ、簡単な構造で加工や組み立ての作業性が良い反射光測定装置を提供する。 測定対象面に向けて光を照射する光源21と、測定対象面からの反射光を受光する受光部24とを含む光学系を収容し、測定対象面の方向に開口を有する収容ケース25と、収容ケース25の開口を封じる窓26と、を備えた反射光測定装置の窓26の一部に、光源21から出射された光の光軸Yに対して所定角度傾斜した出射窓27を設け、光源21から出射された光が、出射窓27を介して測定対象面に向けて照射されるようにした。

    Abstract translation: 提供一种反射光测量装置,其具有简单的结构和良好的加工和组装的可加工性,同时消除了由反射引起的杂散光对窗的顶表面和底表面的影响。 在反射光测量装置的窗口(26)的一部分中,设置有:容纳壳体(25),其容纳包括用于将光照射到被测量表面的光源(21)的光学系统,以及光接收 用于接收来自待测表面的反射光的部分(24),并且具有朝向待测表面的开口; 和用于封闭外壳(25)的开口的窗(26),提供相对于从光源(21)发射的光的光轴(Y)以预定角度倾斜的发射窗(27) ,并且从光源(21)发射的光通过发射窗(27)施加到待测量的表面。

    CLAM-SHELL LUMINOMETER
    313.
    发明申请

    公开(公告)号:WO2014031327A2

    公开(公告)日:2014-02-27

    申请号:PCT/US2013053714

    申请日:2013-08-06

    Inventor: COHEN BERI

    Abstract: A clam-shell luminometer that, when closed, completely encloses an assay reaction mixture-containing reaction vessel and some portion of a reaction carousel or ring. The luminometer includes first and second portions that are coupled to each other, a photomultiplier tube, and plural fiber optic bundles that are optically coupled to the photomultiplier tube. First ends of the fiber optic bundles are disposed adjacent to the reaction vessel in the second portion so that the fiber optic bundles completely surround the perimeter or periphery of the reaction vessel.

    Abstract translation: 蛤壳式发光计在封闭时完全封闭含有测定反应混合物的反应容器和反应传送带或环的一部分。 发光计包括彼此耦合的第一和第二部分,光电倍增管以及光学耦合到光电倍增管的多个光纤束。 光纤束的第一端在第二部分中邻近反应容器设置,使得光纤束完全包围反应容器的周边或周边。

    ANNULAR OPTICAL DEVICE
    314.
    发明申请
    ANNULAR OPTICAL DEVICE 审中-公开
    环形光学器件

    公开(公告)号:WO2012018717A2

    公开(公告)日:2012-02-09

    申请号:PCT/US2011046105

    申请日:2011-08-01

    Inventor: PALUMBO PERRY A

    Abstract: An annular optical device (100) includes an annular meso-optic (1) including an annulus (11) centered about an axis of revolution (A) and a secondary optical structure (2) substantially coaxial within the annulus (11). The secondary optical structure (2) and the annular meso-optic (1) are separated by a media (12) including a media refractive index that is lower than the refractive index of the secondary optical structure. The secondary optical structure (2) holds a specimen to be radiated by impinging electromagnetic radiation. Scattered radiation from the secondary optical structure (2) and within the annulus (11) of the annular meso-optic (1) is allowed into the annular meso-optic (1) if an angle of incidence of the scattered radiation exceeds a predetermined incidence threshold. The annular meso-optic (1) re-directs the scattered radiation to comprise re-directed radiation that is substantially parallel to the axis of revolution (A).

    Abstract translation: 环形光学装置(100)包括环形介质光学器件(1),其包括以旋转轴线(A)为中心的环形空间(11)和在所述环形空间(11)内基本同轴的次级光学结构(2)。 二次光学结构(2)和环形中视镜(1)由介质折射率低于第二光学结构的折射率的介质(12)分开。 二次光学结构(2)通过撞击电磁辐射而保持待辐射的样本。 如果散射辐射的入射角超过预定的入射角,则允许来自环形介质光学器件(1)的二次光学结构(2)和环形空间(11)内的散射辐射进入环形中视镜(1) 阈。 环形介质光学器件(1)重新引导散射辐射,以包括基本上平行于旋转轴线(A)的重新定向的辐射。

    OPTICAL BACKGROUND SUPPRESSION SYSTEMS AND METHODS FOR FLUORESCENCE IMAGING
    315.
    发明申请
    OPTICAL BACKGROUND SUPPRESSION SYSTEMS AND METHODS FOR FLUORESCENCE IMAGING 审中-公开
    光学背景抑制系统和荧光成像方法

    公开(公告)号:WO2011146900A1

    公开(公告)日:2011-11-24

    申请号:PCT/US2011/037456

    申请日:2011-05-20

    CPC classification number: G01N21/6456 G01N2201/064 G01N2201/0642

    Abstract: A fluorescence imaging system having an enclosure having an optical excitation and detection system and features designed to suppress or reduce background fluorescence. In certain aspects, all or a portion of the interior walls has a material finish and texture that provides a surface that absorbs at least a portion of any impinging excitation light and which has low auto-fluorescing properties. In certain aspects, a baffle structure is provided on the interior of the structure and is configured to mask portions of the interior and reduce the opening through which light impinges on the detector. In certain aspects, a platform having an optically transparent window is located in the interior of the housing structure for holding a sample for excitation by excitation light from an excitation source, wherein a light-trap structure is positioned or located on an opposite side of the platform relative to the excitation source and configured to receive and contain a substantial portion of any scattered or transmitted excitation light.

    Abstract translation: 一种荧光成像系统,其具有具有光学激发和检测系统的外壳和被设计为抑制或减少背景荧光的特征。 在某些方面,内壁的全部或一部分具有提供吸收至少一部分任何入射激发光并且具有低自发荧光特性的表面的材料表面和纹理。 在某些方面,挡板结构设置在结构的内部,并且构造成掩盖内部的一部分并且减小光照射在检测器上的开口。 在某些方面,具有光学透明窗口的平台位于壳体结构的内部,用于通过来自激发源的激发光来保持用于激发的样品,其中光阱结构被定位或位于 平台相对于激发源并且被配置为接收和容纳任何散射或透射的激发光的实质部分。

    MODIFIED CARTRIDGE WITH ADSORBENT POLYMER FOR SOLID-PHASE EXTRACTION ( SPE)
    316.
    发明申请
    MODIFIED CARTRIDGE WITH ADSORBENT POLYMER FOR SOLID-PHASE EXTRACTION ( SPE) 审中-公开
    用于固相萃取(SPE)的吸收聚合物的改性盒

    公开(公告)号:WO2009098522A1

    公开(公告)日:2009-08-13

    申请号:PCT/GB2009/050126

    申请日:2009-02-09

    Abstract: A solid phase extraction (SPE) cartridge for use in a fluorimetric assay comprises an elongate container (10) of a material permeable to fluorescent radiation, having an open inlet end and an open outlet end. For assay of a compound of interest, a solid adsorbent stationary phase (11) is provided in the container to adsorb the target compound from a mobile phase. To reduce background fluorescence that may interfere with the assay, at least one region (12,13) that is is at leastpartially impermeable to fluorescent radiation, for example by absorbence, scattering or refracting, is provided in or on the container wall, suitably on the outlet side and/or the inlet side of the anticipated location of a band or layer (14) of a compound of interest adsorbed in the stationary phase during an SPE procedure.

    Abstract translation: 用于荧光测定的固相萃取(SPE)筒包括具有可透过荧光辐射的材料的细长容器(10),其具有开放的入口端和敞开的出口端。 为了测定目的化合物,在容器中提供固体吸附剂固定相(11)以从流动相吸附目标化合物。 为了减少可能干扰测定的背景荧光,至少一个在荧光辐射上至少部分不透过的区域(例如通过吸光度,散射或折射)被设置在容器壁上或容器壁上,适当地在 在SPE程序期间吸附在固定相中的感兴趣的化合物的带或层(14)的预期位置的出口侧和/或入口侧。

    MICROELECTRONIC SENSOR DEVICE WITH A MODULATED LIGHT SOURCE
    317.
    发明申请
    MICROELECTRONIC SENSOR DEVICE WITH A MODULATED LIGHT SOURCE 审中-公开
    具有调制光源的微电子传感器装置

    公开(公告)号:WO2009016533A3

    公开(公告)日:2009-08-06

    申请号:PCT/IB2008052869

    申请日:2008-07-17

    Abstract: The invention relates to a microelectronic sensor device and a method for making optical examinations at a carrier (11), e.g. for the detection of magnetic particles (1) at a contact surface (12) of the carrier (11) by frustrated total internal reflection (FTIR). A light source (21), particularly a laser light source, with a laser modulator (22) are used for emitting an input light beam (L1) into the carrier (11) which is modulated such that optical interferences with reflections (L1') of the input light beam (L1) from the entrance window (14) or other components of the carrier (11) are reduced/minimized. This can for example be achieved by a pulsed on/off modulation in which the first relaxation minimum of a currently emitted pulse (PN) coincides in the light source (21) with the first relaxation maximum of a reflected pulse (PN-1'). By reducing the effect of interferences, the setup is less prone to disturbances from dimensional variations that are e.g. induced by thermal extension.

    Abstract translation: 本发明涉及一种微电子传感器装置和一种用于在载体(11)上进行光学检查的方法。 用于通过沮丧的全内反射(FTIR)检测载体(11)的接触表面(12)处的磁性颗粒(1)。 使用具有激光调制器(22)的光源(21),特别是具有激光光源的光源(21)将输入光束(L1)发射到被调制的载波(11)中,使得与反射(L1')的光学干涉 (14)的输入光束(L1)或载体(11)的其他部件的距离减小/最小化。 这可以例如通过脉冲开/关调制实现,其中当前发射的脉冲(PN)的第一弛豫最小值与光源(21)中的第一弛豫最小值与反射脉冲(PN-1')的第一弛豫最大值一致, 。 通过减少干扰的影响,该装置不容易受到尺寸变化的干扰。 由热延伸引起。

    GAS CONTENT MEASURING APPARATUS AND METHOD
    318.
    发明申请
    GAS CONTENT MEASURING APPARATUS AND METHOD 审中-公开
    气体含量测量装置和方法

    公开(公告)号:WO2006030059A1

    公开(公告)日:2006-03-23

    申请号:PCT/FI2005/000387

    申请日:2005-09-08

    Inventor: KERÄNEN, Reino

    Abstract: This publication discloses an apparatus and method for measuring a gas content. The apparatus includes a light transmitter (1), by means of which coherent light can be sent to the measurement object (3), a receiver (2), by means of which light that has passed through the measurement object (3) can be detected, and optical means (4, 5, 6), by means of which the light intensity of the light transmitter (1) can be aimed at the receiver (2). According to the invention, the optical means include a lens element (4), the optical axis of which is arranged essentially obliquely relative to the longitudinal axis of the measurement object (3), so that the angles of the normals of the optical boundaries relative to the measuring signal are set obliquely. The lens element (4) is both a refracting and a reflecting element, and separates the measurement object (3) from the means (1, 2, 5)

    Abstract translation: 该出版物公开了一种用于测量气体含量的装置和方法。 该装置包括光发射器(1),通过该光发射器可以将相干光发射到测量对象(3),接收器(2)借助于该光发射器(2),已经通过测量对象(3)的光可以是 检测和光学装置(4,5,6),借助于该装置,光发射器(1)的光强度可以瞄准接收器(2)。 根据本发明,光学装置包括透镜元件(4),其光轴相对于测量对象(3)的纵向轴线基本上倾斜地布置,使得光学边界的法线的角度相对于 测量信号倾斜设定。 透镜元件(4)同时是折射和反射元件,并且将测量对象(3)与装置(1,2,5)分离,

    生体情報測定用光学素子およびそれを用いた生体情報測定装置
    319.
    发明申请
    生体情報測定用光学素子およびそれを用いた生体情報測定装置 审中-公开
    用于测量生物信息的光学元件和使用其的生物信息测量仪器

    公开(公告)号:WO2005092192A1

    公开(公告)日:2005-10-06

    申请号:PCT/JP2005/005708

    申请日:2005-03-28

    Abstract:  高精度で安定的かつ容易に、生体などの被検試料中の体液成分を非侵襲的に測定することができる生体情報測定用光学素子を提供する。光入射面と、生体に接し前記生体を隆起させる溝部を有する接触面と、光出射面とを有し、前記光入射面から入射した光を前記生体に照射し、前記生体により吸収・散乱された光を受光するとともに前記光出射面から外部に出射し、前記生体の情報を光学的に測定するための光学素子において、溝部に光透過制御手段を設け、前記光透過制御手段は、前記溝部の谷部の底部から、前記溝部の前記光入射面側および/または前記光出射面側の壁面の少なくとも一部に形成する。  

    Abstract translation: 用于测量要检查的样品中的幽默成分的生物学信息的光学元件,例如, 一个活体,可以非常方便,稳定地测量,高精度。 在具有光入射面的光学元件中,接触生物体的接触面设置有用于使生物体突出的凹槽和光出射面,并且通过照射生物体来光学地测量生物体的信息 利用来自光入射面的入射光,接收由生物体吸收/散射的光并从光出射面输出光,光传输控制装置设置在凹槽部分处并形成在壁的至少一部分 在槽部的光入射面侧和/或光出射面侧面与其底部面对。

    FLOW CELLS UTILIZING PHOTOMETRIC TECHNIQUES
    320.
    发明申请
    FLOW CELLS UTILIZING PHOTOMETRIC TECHNIQUES 审中-公开
    流动细胞利用光学技术

    公开(公告)号:WO2004099757A1

    公开(公告)日:2004-11-18

    申请号:PCT/US2003/011281

    申请日:2003-04-07

    Applicant: SYSTEC, INC.

    Abstract: A flow cell (10) for transporting fluid in a radiant energy field includes a cell body (12) having a tube (20) extending therethrough including a radiant energy blocking portion integral therewith. In a particular embodiment, the cell body (12) includes one or more end caps (14, 16) having a protrusion (40) may be inserted into the tube (20) to create a fluid seal, the end caps (14, 16) including open channels for transporting fluid (28, 32) and radiant energy (26, 30) therethrough, and the tube (20) in the cell body (12) includes an efficient radiant energy transmission lining that is spaced from the end cap protrusions (40), thereby forming a gap volume in the flow cell open channel (18), which gap volume may be calibrated such that radiant energy losses may be standardized in respective flow cells transporting fluids having various indices of refraction.

    Abstract translation: 用于在辐射能场中传送流体的流动池(10)包括具有延伸穿过其中的管(20)的电池体(12),其包括与其成一体的辐射能阻挡部分。 在特定实施例中,电池体(12)包括具有突起(40)的一个或多个端盖(14,16)可以插入管(20)中以产生流体密封,端盖(14,16) )包括用于输送流体(28,32)和通过其中的辐射能(26,30)的开放通道,并且电池体(12)中的管(20)包括有效的辐射能传输衬里,其与端盖突起 (40),从而在流动池开放通道(18)中形成间隙体积,该间隙体积可以被校准,使得辐射能损失可以在传输具有各种折射率的流体的流动池中标准化。

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