Detection method
    39.
    发明专利
    Detection method 审中-公开
    检测方法

    公开(公告)号:JP2014158468A

    公开(公告)日:2014-09-04

    申请号:JP2014043282

    申请日:2014-03-05

    Abstract: PROBLEM TO BE SOLVED: To provide a detection method using an array of nucleic acid molecules of which the expression profiles characterize an anatomical origin of a cell or a population of cells within the large intestine.SOLUTION: The invention relates to a method for determining an anatomical origin of a cell or a population of cells derived from a large intestine of an individual, comprising: obtaining an expression training data representing an expression of genes in cells or populations of cells derived from proximal-distal origins of at least one large intestine, and training data including a proximal-distal origin training data representing associations of the cells or the populations of cells with the proximal-distal origins; processing the training data to generate a classification data representing a linear or non-linear combination of expression levels of the genes.

    Abstract translation: 要解决的问题:提供使用核酸分子阵列的检测方法,所述核酸分子阵列的特征在于大肠细胞的解剖起源或大肠内的细胞群体。解决方案:本发明涉及一种确定 来自个体的大肠的细胞或细胞群的解剖学起源,包括:获得代表来自至少一个大肠的近端远端起源的细胞或细胞群体中的基因表达的表达训练数据, 以及训练数据,包括表示细胞或细胞群与近端远端起源的关联的近端远端起始训练数据; 处理训练数据以产生表示基因的表达水平的线性或非线性组合的分类数据。

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