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    SPECIFIC AND HIGH AFFINITY BINDING PROTEINS COMPRISING MODIFIED SH3 DOMAINS OF FYN KINASE
    37.
    发明申请
    SPECIFIC AND HIGH AFFINITY BINDING PROTEINS COMPRISING MODIFIED SH3 DOMAINS OF FYN KINASE 审中-公开
    包含修饰的FYN激酶SH3结构域的特异性和高亲和力结合蛋白

    公开(公告)号：WO2008022759A3

    公开(公告)日：2008-04-17

    申请号：PCT/EP2007007324

    申请日：2007-08-20

    Applicant: EIDGENOESS TECH HOCHSCHULE ,  GRABULOVSKI DRAGAN ,  NERI DARIO

    Inventor： GRABULOVSKI DRAGAN ,  NERI DARIO

    IPC: C07K14/435

    CPC classification number: C12N9/1205

    Abstract: The present invention relates to a recombinant binding protein comprising at least one derivative of the Src homology 3 domain (SH3) of the FYN kinase, wherein at least one amino acid in or positioned up to two amino acids adjacent to the src loop and/or at least one amino acid in or positioned up to two amino acids adjacent to the RT loop is substituted, deleted or added. Furthermore, the invention is directed to fusion proteins comprising a binding protein according to the invention fused to a pharmaceutically and/or diagnostically active component. In addition, the invention concerns nucleotides coding for these binding and/or fusion proteins as well as corresponding vectors and host cells. Last but not least, the present invention relates to the use of binding and/or fusion proteins of the present invention for preparing a medicament or a diagnostic means as well as to pharmaceutical or diagnostic compositions comprising said binding and/or fusion proteins.

    Abstract translation: 本发明涉及包含FYN激酶的Src同源性3结构域（SH3）的至少一种衍生物的重组结合蛋白，其中至少一个位于或位于与src环相邻的两个氨基酸处的至少一个氨基酸和/或 在与RT环相邻的两个氨基酸中或位于其上的至少一个氨基酸被取代，缺失或添加。 此外，本发明涉及包含与药学和/或诊断活性组分融合的根据本发明的结合蛋白的融合蛋白。 另外，本发明涉及编码这些结合蛋白和/或融合蛋白的核苷酸以及相应的载体和宿主细胞。 最后但并非最不重要的是，本发明涉及本发明的结合蛋白和/或融合蛋白在制备药物或诊断手段中的用途以及包含所述结合蛋白和/或融合蛋白的药物或诊断组合物。

    DISPLAYING INFORMATION INTERACTIVELY
    38.
    发明申请
    DISPLAYING INFORMATION INTERACTIVELY 审中-公开
    显示信息互动

    公开(公告)号：WO2007131382A2

    公开(公告)日：2007-11-22

    申请号：PCT/CH2007000248

    申请日：2007-05-15

    Applicant: EIDGENOESS TECH HOCHSCHULE ,  GROSS MARKUS ,  COTTING DANIEL

    Inventor： GROSS MARKUS ,  COTTING DANIEL

    IPC: G06F3/042

    CPC classification number: G06F3/0425 ,  G06F3/033 ,  G06F3/0386 ,  H04N9/3194

    Abstract: An arrangement for displaying information on a display surface is provided, the arrangement comprising a computing unit and a projecting unit. The computing unit is capable of supplying a display control signal to the projecting unit and to thereby cause the projecting unit to project a display image calculated by the computing unit onto the display surface. The arrangement further includes a detecting unit, the detecting unit being capable of detecting a pointing signal applied to the display surface by a user and of supplying, depending on the pointing signal, a pointing information to the computing unit. The computing unit can calculate the display image including at least one image unit, wherein at least one of the position, the size and of the shape of the at least one image unit is dependent on the pointing information.

    Abstract translation: 提供了一种用于在显示表面上显示信息的装置，该装置包括计算单元和投影单元。 计算单元能够向投影单元提供显示控制信号，从而使投影单元将由计算单元计算的显示图像投影到显示表面上。 该装置还包括检测单元，该检测单元能够检测由用户施加到显示表面的指示信号，并且根据指向信号向计算单元提供指向信息。 计算单元可以计算包括至少一个图像单元的显示图像，其中至少一个图像单元的位置，大小和形状中的至少一个取决于指向信息。

    UNIQUE LABEL FOR IDENTIFICATION OR SECURITY SYSTEM
    39.
    发明申请
    UNIQUE LABEL FOR IDENTIFICATION OR SECURITY SYSTEM 审中-公开
    用于识别或安全系统的独特标签

    公开(公告)号：WO2007002873A2

    公开(公告)日：2007-01-04

    申请号：PCT/US2006025476

    申请日：2006-06-29

    Applicant: EIDGENOESS TECH HOCHSCHULE ,  SPENCER NICHOLAS ,  UGGOWITZER PETER ,  SMITH PAUL ,  FELDMAN KIRILL

    Inventor： SPENCER NICHOLAS ,  UGGOWITZER PETER ,  SMITH PAUL ,  FELDMAN KIRILL

    CPC classification number: G06K19/086 ,  B42D25/29 ,  G09F3/00 ,  G09F3/02 ,  G09F3/0292 ,  Y10S283/904 ,  Y10T29/49

    Abstract: Unique labels for security or identification purposes, methods of making the labels and uses for the labels are described herein. The label is formed from one or more crystalline materials, optionally in combination with a non¬ crystalline material, or from a combination of polymers, and has a unique, detectable pattern. In one embodiment, the label is formed from a crystalline material, preferably a metallic material, which naturally contains a unique grain structure, with unique reflective properties. In a preferred embodiment, the label is formed of a metallic material that has been recrystallized to enlarge the size of the grains so that they are visible to the unaided human eye. In another embodiment, the label is formed from a combination of two or more polymers, which are mixed together at elevated temperatures and/or in solvents and form a unique pattern upon removal of the solvent and/or cooling. Optionally, the label contains an identifier in the form of words, numbers, or letters, or a combination thereof. The label can be placed on any item or document. Following manufacture of the label, it is imaged with a particular light source or combination of light sources at one or more imaging angles; the label is numbered; and data describing the image, angle data and number are stored, hi an alternative embodiment, the pattern may be discernable by applying a liquid or vapor to the surface. Preferably the data includes a stored image. In the preferred use of the label and security system, this information is only known by the end user of the identification system. To verify the authenticity of the labeled item, the label is imaged at the same angles as the stored data and compared to the stored image using pattern-recognition software.

    Abstract translation: 本文描述了用于安全或识别目的的唯一标签，制作标签的标签和用途的方法。 标签由一种或多种结晶材料形成，任选地与非结晶材料组合，或由聚合物的组合形成，并且具有独特的可检测图案。 在一个实施方案中，标签由结晶材料形成，优选为金属材料，其天然含有独特的晶粒结构，具有独特的反射特性。 在优选的实施方案中，标签由已经重结晶的金属材料形成，以扩大颗粒的尺寸，使得它们对于肉眼可见。 在另一个实施方案中，标记由两种或更多种聚合物的组合形成，其在高温和/或溶剂下混合在一起，并且在除去溶剂和/或冷却时形成独特的图案。 可选地，标签包含字母，数字或字母形式的标识符，或其组合。 标签可以放在任何物品或文件上。 在制造标签之后，用一个或多个成像角度的特定光源或光源的组合对其进行成像; 标签编号; 并且存储描述图像，角度数据和数量的数据。在替代实施例中，可以通过将液体或蒸气施加到表面来识别图案。 优选地，数据包括存储的图像。 在标签和安全系统的优选使用中，该信息仅由识别系统的最终用户知道。 为了验证标签项目的真实性，标签以与存储的数据相同的角度成像，并使用模式识别软件与存储的图像进行比较。

    SYSTEM AND METHOD FOR A COOPERATIVE ARM THERAPY AND CORRESPONDING ROTATION MODULE
    40.
    发明申请
    SYSTEM AND METHOD FOR A COOPERATIVE ARM THERAPY AND CORRESPONDING ROTATION MODULE 审中-公开
    系统和方法，用于合作的ARM治疗和旋转模块

    公开(公告)号：WO2006058442A8

    公开(公告)日：2006-08-31

    申请号：PCT/CH2005000236

    申请日：2005-04-28

    Applicant: EIDGENOESS TECH HOCHSCHULE ,  UNIV ZUERICH ,  NEF TOBIAS ,  RIENER ROBERT ,  WEGMANN DANIEL ,  COLOMBO GERY

    Inventor： NEF TOBIAS ,  RIENER ROBERT ,  WEGMANN DANIEL ,  COLOMBO GERY

    IPC: A61H1/02 ,  B25J9/00

    CPC classification number: A61H1/0274 ,  A61H1/0277 ,  A61H1/0281 ,  A61H2001/0203 ,  A63B21/4017 ,  A63B21/4049 ,  A63B23/03508 ,  A63B23/1209 ,  A63B23/1245 ,  B25J9/0006

    Abstract: A system used in arm therapy comprises a plurality of drives. A first drive (11) and a second drive (26) determine the position of an upper arm rotation module (16, 17), the upper arm of a user being fixed by means of a cuff (10). The upper arm rotation module (16, 17) is a two-piece structure and is provided with a third rotation drive (29) for rotating the upper arm cuff (10), which is positioned inwards (17) and substantially has the shape of a hollow cylinder when closed, about its main axis in relation to the outer part (16) of the upper arm rotation module (16, 17). The upper arm rotation module (16, 17) is linked with a wrist rotation module (20, 21) via an elbow rotation module (22, 23) which can be rotated at an angle thereto and is embodied similar to the upper arm rotation module. The inventive system allows an internal and external shoulder rotation, flexion or extension of the elbow and pronation/supination of the forearm, which is effected as a relative movement of the cuffs (8, 9 and 10) due to the various drives.

    Abstract translation: 手臂治疗系统有几个驱动器。 第一驱动装置（11）和第二驱动装置（26）确定上臂旋转模块（16,17）的位置，可以用套环（10）固定使用者的上臂。 上臂旋转模块（16，17）是两个部分，和第三旋转驱动器（29）设置于所述内位于围绕其主相对于上臂旋转模块的外部部分（16）轴线的关闭状态（10）（17）大致为中空圆柱形的上部臂套 （16,17）转身。 上臂旋转模块16,17通过横向旋转的肘部旋转模块20,21与腕部旋转模块20,21连接，该肘部旋转模块20,21与前者相同地构成。 这允许由各种驱动器引起的内侧和外侧肩部旋转，肘的弯曲或伸展以及前臂的前/后旋转，从而使袖子（8,9和10）彼此相对移动。

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