公开(公告)号：US6008052A

公开(公告)日：1999-12-28

申请号：US897616

申请日：1992-06-10

Applicant: Kenneth A. Davis ,  Anthony J. Ward

Inventor： Kenneth A. Davis ,  Anthony J. Ward

IPC: G01N1/28 ,  C12N5/08 ,  G01N15/14 ,  G01N33/48 ,  G01N33/50 ,  G01N33/53 ,  G01N33/533 ,  G01N33/543 ,  G01N33/569 ,  G01N33/96

CPC classification number: G01N33/5005 ,  G01N33/5094 ,  G01N33/56972 ,  G01N33/56977 ,  G01N33/96 ,  G01N15/14 ,  G01N2496/05 ,  Y10T436/101666

Abstract: Cells fixed with a fixative, reduced with a Schiff's base reducing agent and then dried in the presence of .alpha.-.alpha.-trehalose retain their light scatter and fluorescence properties and may be used, when rehydrated, as standards or controls in cellular analysis.

Abstract translation: 用固定剂固定的细胞，用希夫碱还原剂还原，然后在α-α-海藻糖存在下干燥，保留其光散射和荧光性质，并可在细胞分析中作为标准品或对照进行再水合时使用。

公开(公告)号：US5869641A

公开(公告)日：1999-02-09

申请号：US799949

申请日：1997-02-14

Applicant: Sumedha Jayasena ,  Kenneth A. Davis ,  Larry Gold

Inventor： Sumedha Jayasena ,  Kenneth A. Davis ,  Larry Gold

IPC: C07B61/00 ,  C07H19/06 ,  C07H19/10 ,  C07H21/00 ,  C07K14/00 ,  C12N9/12 ,  C12N15/10 ,  C12Q1/37 ,  C12Q1/68 ,  C12Q1/70 ,  F02B75/02 ,  G01N33/531 ,  G01N33/532 ,  G01N33/535 ,  G01N33/569 ,  G01N33/68 ,  G01N33/76 ,  C07H21/02 ,  C12P19/34

CPC classification number: C12N15/115 ,  C07H19/06 ,  C07H19/10 ,  C07H21/00 ,  C07K14/001 ,  C12N15/1048 ,  C12N9/1276 ,  C12Q1/37 ,  G01N33/531 ,  G01N33/532 ,  G01N33/535 ,  G01N33/56988 ,  G01N33/68 ,  G01N33/76 ,  C12N2310/13 ,  C12N2310/16 ,  C12N2310/321 ,  C12N2310/322 ,  C12N2310/53 ,  C12N2320/13 ,  C40B40/00 ,  F02B2075/027 ,  G01N2333/163 ,  G01N2333/8125 ,  G01N2333/96433 ,  G01N2333/96436 ,  G01N2333/96486 ,  G01N2333/966 ,  G01N2333/974

Abstract: Methods are described for the identification and preparation of high-affinity nucleic acid ligands to CD4. Included in the invention are specific 2'F RNA ligands to CD4 identified by the SELEX method.

Abstract translation: 描述了用于鉴定和制备CD4的高亲和力核酸配体的方法。 包括在本发明中的是通过SELEX方法鉴定的特异性2'F RNA配体。