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    METHOD OF TRANSFERRING BEADS
    34.
    发明公开
    METHOD OF TRANSFERRING BEADS 有权
    转移珠子的方法

    公开(公告)号：EP3158333A1

    公开(公告)日：2017-04-26

    申请号：EP15730768.7

    申请日：2015-06-19

    Applicant: Spinchip Diagnostics AS

    Inventor： BORCH, Stig Morten ,  HAMSUND, Torgeir ,  HOLTLUND, Jostein Geir ,  GULLIKSEN, Anja

    IPC: G01N33/543

    CPC classification number: G01N1/10 ,  B01L3/502753 ,  B01L3/502761 ,  B01L2200/0647 ,  B01L2200/10 ,  B01L2400/0409 ,  B01L2400/0487 ,  B03D3/00 ,  G01N33/54313 ,  G01N33/54333 ,  G01N33/54366 ,  G01N2001/1006 ,  G01N2035/0449

    Abstract: The present invention provides a method of analyzing a sample containing an analyte to be qualitatively and/or quantitatively determined, comprising a binding step and a washing step, wherein the binding step comprises: interacting the analyte with beads having a density m1; obtaining a structure of packed beads comprising quantifiable bead complexes having a density m2; and the washing step comprises: dispersing the packed beads in a liquid medium having a density d>m2 and m1; and separating the liquid medium and the beads comprising the quantifiable bead complexes.

    Abstract translation: 本发明提供了一种在流体芯片中转移珠子的方法，该流体芯片包括内部流体回路，其中至少一种反应物是珠粒的各种反应物可通过该内部流体回路通过使用离心力而移动，该方法包括以下步骤： 在所述流体回路的区段（7,15）中提供具有等于或小于ml的密度的珠（8），所述区段包括至少第一出口（16,13）; 向该部分提供第一液体介质，该液体介质具有密度d 2，使得d 2> ml; 并施加离心力使得珠子沿离心力的相反方向迁移。

    PROCESSING CARTRIDGE
    35.
    发明公开
    PROCESSING CARTRIDGE 审中-公开

    公开(公告)号：EP4501456A3

    公开(公告)日：2025-04-09

    申请号：EP24219203.7

    申请日：2021-11-30

    Applicant: SpinChip Diagnostics AS

    Inventor： STENMARK, Sebastian ,  BORCH, Stig, Morten ,  HAMSUND, Torgeir ,  MEYER, Erik L. ,  JAHREN, Rolf ,  KRISTIANSEN, Håvard ,  STAAL, Odd Martin ,  HILL, Steven ,  PAUS, Didrik ,  KAVLI, Ole-Andreas

    IPC: B01L3/00

    Abstract: The present invention provides a processing cartridge (1) comprising a main cartridge section (2) and an actuating cartridge section (3), the main cartridge section (2) comprises a liquid reservoir chamber (4), a liquid container (5), a container piercing element (6) and a resilient container holding element (9), wherein the actuating cartridge section (3) is configured to dock with the main cartridge section (2) and comprises an actuating member (10) configured to interact with the liquid container (5) during docking; the liquid container, the piercing element (6) and the container holding element (9) are arranged in the liquid reservoir chamber (4), the liquid container is filled with a suitable processing liquid and features a pierceable dispensing side (16), and the container piercing element faces the dispensing side; the liquid container (5) is held in a first position by the container holding element, wherein the dispensing side is separated from the container piercing element; and the actuating member (10) is configured to move the liquid container from the first position to a second position during docking of the cartridge actuating section, and in the second position the dispensing side (16) is pierced by the container piercing element.

    PROCESSING CARTRIDGE
    37.
    发明公开
    PROCESSING CARTRIDGE 审中-公开

    公开(公告)号：EP4501456A2

    公开(公告)日：2025-02-05

    申请号：EP24219203.7

    申请日：2021-11-30

    Applicant: SpinChip Diagnostics AS

    Inventor： STENMARK, Sebastian ,  BORCH, Stig, Morten ,  HAMSUND, Torgeir ,  MEYER, Erik L. ,  JAHREN, Rolf ,  KRISTIANSEN, Håvard ,  STAAL, Odd Martin ,  HILL, Steven ,  PAUS, Didrik ,  KAVLI, Ole-Andreas

    IPC: B01L3/00

    Abstract: The present invention provides a processing cartridge (1) comprising a main cartridge section (2) and an actuating cartridge section (3), the main cartridge section (2) comprises a liquid reservoir chamber (4), a liquid container (5), a container piercing element (6) and a resilient container holding element (9), wherein the actuating cartridge section (3) is configured to dock with the main cartridge section (2) and comprises an actuating member (10) configured to interact with the liquid container (5) during docking; the liquid container, the piercing element (6) and the container holding element (9) are arranged in the liquid reservoir chamber (4), the liquid container is filled with a suitable processing liquid and features a pierceable dispensing side (16), and the container piercing element faces the dispensing side; the liquid container (5) is held in a first position by the container holding element, wherein the dispensing side is separated from the container piercing element; and the actuating member (10) is configured to move the liquid container from the first position to a second position during docking of the cartridge actuating section, and in the second position the dispensing side (16) is pierced by the container piercing element.

    ANALYTICAL METHOD
    40.
    发明公开
    ANALYTICAL METHOD 有权
    分析方法

    公开(公告)号：EP3158332A1

    公开(公告)日：2017-04-26

    申请号：EP15730158.1

    申请日：2015-06-19

    Applicant: Spinchip Diagnostics AS

    Inventor： BORCH, Stig Morten ,  HAMSUND, Torgeir ,  HOLTLUND, Jostein Geir ,  GULLIKSEN, Anja

    IPC: G01N33/543

    CPC classification number: G01N1/10 ,  B01L3/502753 ,  B01L3/502761 ,  B01L2200/0647 ,  B01L2200/10 ,  B01L2400/0409 ,  B01L2400/0487 ,  B03D3/00 ,  G01N33/54313 ,  G01N33/54333 ,  G01N33/54366 ,  G01N2001/1006 ,  G01N2035/0449

    Abstract: The present invention provides a method of analyzing a sample containing an analyte to be qualitatively and/or quantitatively determined, comprising a binding step and a washing step, wherein the binding step comprises: interacting the analyte with beads having a density m1; obtaining a structure of packed beads comprising quantifiable bead complexes having a density m2; and the washing step comprises: dispersing the packed beads in a liquid medium having a density d>m2 and m1; and separating the liquid medium and the beads comprising the quantifiable bead complexes.

    Abstract translation: 本发明提供了一种在流体芯片中转移珠子的方法，该流体芯片包括内部流体回路，其中至少一种反应物是珠粒的各种反应物可通过该内部流体回路通过使用离心力而移动，该方法包括以下步骤： 在所述流体回路的区段（7,15）中提供具有等于或小于ml的密度的珠（8），所述区段包括至少第一出口（16,13）; 向该部分提供第一液体介质，该液体介质具有密度d 2，使得d 2> ml; 并施加离心力使得珠子沿离心力的相反方向迁移。

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